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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:bupranolol
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Accession:CHEBI:135123 term browser browse the term
Synonyms:related_synonym: Formula=C14H22ClNO2;   InChI=1S/C14H22ClNO2/c1-10-5-6-12(15)13(7-10)18-9-11(17)8-16-14(2,3)4/h5-7,11,16-17H,8-9H2,1-4H3;   InChIKey=HQIRNZOQPUAHHV-UHFFFAOYSA-N;   SMILES=O(CC(CNC(C)(C)C)O)C1=C(Cl)C=CC(=C1)C;   bupranol;   bupranolol HCl;   bupranolol hydrochloride
 xref: CAS:14556-46-8;   Drug_Central:433;   HMDB:HMDB0015697
 xref_mesh: MESH:D002046


show annotations for term's descendants           Sort by:
bupranolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 multiple interactions
decreases activity		 ISO [Bupranolol co-treated with ADRB1] results in increased abundance of Cyclic AMP; Bupranolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]
Bupranolol results in decreased activity of ADRB1 protein		 CTD PMID:2565296 PMID:12761341 PMID:15060759 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19834
    chemical entity 19832
      group 19791
        polyatomic entity 19790
          molecule 19695
            organic molecule 19680
              organic cyclic compound 19493
                organic aromatic compound 19360
                  aromatic ether 16526
                    bupranolol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19834
    subatomic particle 19832
      composite particle 19832
        hadron 19832
          baryon 19832
            nucleon 19832
              atomic nucleus 19832
                atom 19832
                  main group element atom 19782
                    main group molecular entity 19782
                      p-block molecular entity 19782
                        carbon group molecular entity 19731
                          organic molecular entity 19727
                            heteroorganic entity 19484
                              organochalcogen compound 19248
                                organooxygen compound 19165
                                  ether 17280
                                    aromatic ether 16526
                                      bupranolol 1
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