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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1,2-dihexadecanoyl-sn-glycero-3-phosphocholine
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Accession:CHEBI:72999 term browser browse the term
Definition:A phosphatidylcholine 32:0 in which the 1- and 2-acyl groups are specified as hexadecanoyl (palmitoyl). A synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of pulmonary surfactants.
Synonyms:exact_synonym: (2R)-2,3-bis(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate;   (2R)-2,3-bis(hexadecanoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
 related_synonym: 1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine;   1,2-Dipalmitoyl-L-lecithin;   1,2-Dipalmitoyl-sn-glycero-3-phosphatidylcholine;   1,2-dipalmitoyl-sn-glycero-3-phosphocholine;   1,2-dipalmitoylphosphatidylcholine;   1-16:0-2-16:0-phosphatidylcholine;   16:0-16:0-PC;   Dipalmitoyl phosphatidylcholine;   Formula=C40H80NO8P;   GPC(16:0/16:0);   GPCho 16:0/16:0;   InChI=1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1;   InChIKey=KILNVBDSWZSGLL-KXQOOQHDSA-N;   PC(32:0);   Palmitato de colfoscerilo;   Phosphatidylcholine(32:0);   SMILES=CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC;   colfosceril palmitate;   colfoscerili palmitas;   dipalmitoyl-GPC;   dipalmitoylphosphatidylcholine;   palmitate de colfosceril;   phosphatidylcholine 16:0/16:0
 alt_id: CHEBI:44843;   CHEBI:73797;   CHEBI:77026
 xref: CAS:2644-64-6;   CAS:63-89-8;   Drug_Central:730;   HMDB:HMDB0000564;   LIPID_MAPS_instance:LMGP01010564
 xref_mesh: MESH:D015060
 xref: MetaCyc:1-2-DIPALMITOYLPHOSPHATIDYLCHOLINE;   PDBeChem:PCF;   PMID:12950167;   PMID:22888753;   Reaxys:1917966;   Reaxys:5799515;   Wikipedia:Dipalmitoylphosphatidylcholine
 cyclic_relationship: is_conjugate_base_of CHEBI:40265


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1,2-dihexadecanoyl-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 multiple interactions ISO 1,2-Dipalmitoylphosphatidylcholine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein] CTD PMID:19041333 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Prnp prion protein multiple interactions
affects folding		 ISO Copper affects the reaction [1,2-Dipalmitoylphosphatidylcholine affects the folding of PRNP protein modified form] CTD PMID:20936829 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      chemical role 19420
        emulsifier 7429
          surfactant 7429
            1,2-dihexadecanoyl-sn-glycero-3-phosphocholine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      chalcogen 19513
                        oxygen atom 19488
                          oxygen molecular entity 19488
                            hydroxides 19299
                              oxoacid 18736
                                pnictogen oxoacid 13211
                                  phosphorus oxoacid 12414
                                    phosphoric acids 11418
                                      phosphoric acid 11418
                                        phosphoric acid derivative 11227
                                          phosphate 11226
                                            organic phosphate 11226
                                              phospholipid 316
                                                glycerophospholipid 211
                                                  glycerophosphocholine 124
                                                    phosphatidylcholine 82
                                                      1,2-diacyl-sn-glycero-3-phosphocholine 23
                                                        phosphatidylcholine 32:0 2
                                                          1,2-dihexadecanoyl-sn-glycero-3-phosphocholine 2
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