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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(+)-(S)-ar-turmerone
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Accession:CHEBI:70159 term browser browse the term
Definition:A sesquiterpenoid that is 2-methylhept-2-en-4-one substituted by a 4-methylphenyl group at position 6. It has been isolated from Peltophorum dasyrachis.
Synonyms:exact_synonym: (6S)-2-methyl-6-(4-methylphenyl)hept-2-en-4-one
 related_synonym: Formula=C15H20O;   InChI=1S/C15H20O/c1-11(2)9-15(16)10-13(4)14-7-5-12(3)6-8-14/h5-9,13H,10H2,1-4H3/t13-/m0/s1;   InChIKey=NAAJVHHFAXWBOK-ZDUSSCGKSA-N;   SMILES=C[C@@H](CC(=O)C=C(C)C)c1ccc(C)cc1
 xref: CAS:532-65-0
 xref_mesh: MESH:C078098
 xref: PMID:21189039;   Reaxys:3606512


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(+)-(S)-ar-turmerone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO ar-turmerone results in increased expression of ABCB1 mRNA CTD PMID:22181075 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Ahr aryl hydrocarbon receptor increases activity
multiple interactions		 ISO ar-turmerone results in increased activity of AHR protein
ar-turmerone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]		 CTD PMID:29191726 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO ar-turmerone results in increased expression of BAX mRNA; ar-turmerone results in increased expression of BAX protein CTD PMID:19250610 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Casp3 caspase 3 increases activity ISO ar-turmerone results in increased activity of CASP3 protein CTD PMID:19250610 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions		 ISO ar-turmerone results in increased expression of CYP1A1 mRNA
ar-turmerone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]		 CTD PMID:29191726 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO ar-turmerone binds to PPARG protein CTD PMID:15713005 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO ar-turmerone results in increased expression of TP53 mRNA; ar-turmerone results in increased expression of TP53 protein CTD PMID:19250610 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      biological role 19782
        biochemical role 19496
          metabolite 19484
            eukaryotic metabolite 19307
              plant metabolite 17943
                (+)-(S)-ar-turmerone 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbonyl compound 18869
                                    ketone 17165
                                      alpha,beta-unsaturated ketone 9960
                                        enone 9960
                                          (+)-(S)-ar-turmerone 7
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