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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:5'-hydroxyomeprazole
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Accession:CHEBI:63840 term browser browse the term
Definition:A sulfoxide that is omeprazole in which one of the methyl hydrogens at position 5 on the pyridine ring is substituted by a hydroxy group.
Synonyms:exact_synonym: (4-methoxy-6-{[(5-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl}-5-methylpyridin-3-yl)methanol
 related_synonym: 5-Methoxy-2-(((4-methoxy-3-methyl-5-hydroxymethyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole;   Formula=C17H19N3O4S;   Hydroxyomeprazole;   InChI=1S/C17H19N3O4S/c1-10-15(18-7-11(8-21)16(10)24-3)9-25(22)17-19-13-5-4-12(23-2)6-14(13)20-17/h4-7,21H,8-9H2,1-3H3,(H,19,20);   InChIKey=CMZHQFXXAAIBKE-UHFFFAOYSA-N;   SMILES=COc1ccc2[nH]c(nc2c1)S(=O)Cc1ncc(CO)c(OC)c1C
 xref: CAS:92340-57-3
 xref_mesh: MESH:C049963
 xref: PMID:19166730;   PMID:21546194;   PMID:7781266;   PMID:8550990;   PMID:9916309;   Reaxys:8439890


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5'-hydroxyomeprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP 5-hydroxymethylomeprazole results in increased expression of CYP1A1 protein CTD PMID:10103034 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    chemical entity 19839
      chemical substance 14405
        mixture 13722
          racemate 12097
            omeprazole 406
              5'-hydroxyomeprazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            organic molecule 19686
                              organic cyclic compound 19498
                                organic heterocyclic compound 18876
                                  organic heteropolycyclic compound 18301
                                    organic heterobicyclic compound 17235
                                      benzimidazoles 1178
                                        5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole 406
                                          esomeprazole 406
                                            omeprazole 406
                                              5'-hydroxyomeprazole 1
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