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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cyclooxygenase 2 inhibitor
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Accession:CHEBI:50629 term browser browse the term
Definition:A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2.
Synonyms:related_synonym: COX-2 inhibitor;   COX-2 inhibitors;   PGHS-2 inhibitor;   PGHS-2 inhibitors;   cyclo-oxygenase 2 inhibitor;   cyclo-oxygenase-2 inhibitors;   cyclooxygenase-2 inhibitors;   prostaglandin H synthase-2 inhibitor;   prostaglandin H synthase-2 inhibitors;   prostaglandin-endoperoxide synthase 2 inhibitor;   prostaglandin-endoperoxide synthase 2 inhibitors
 xref: Wikipedia:Prostaglandin-endoperoxide_synthase_2


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      CHEBI ontology 19808
        role 19784
          biological role 19782
            biochemical role 19496
              enzyme inhibitor 18704
                EC 1.* (oxidoreductase) inhibitor 17505
                  EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor 15945
                    EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor 14198
                      EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor 14197
                        cyclooxygenase 2 inhibitor 13631
                          (+)-conocarpan 2
                          (-)-larreatricin 0
                          (2S,3S)-2,3-dihydro-3-hydroxymethyl-2-(4-hydroxyphenyl)-5-(E)-propenylbenzofuran 0
                          (E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside 0
                          (RS)-mallotophilippen E 0
                          (S)-etodolac 0
                          (S)-ketorolac + 21
                          1-(4'-hydroxy-3'-methoxyphenyl)-7-phenyl-3-heptanone 0
                          1-(all-cis-docosa-7,10,13,16-tetraenoyl)glycerol 0
                          13,14,15,16-tetranorlabdane-8alpha,12,18-triol 0
                          2-(2,4-dihydroxyphenyl)-5-(E)-propenylbenzofuran 0
                          2-(2-hydroxy-4-methoxyphenyl)-5-(3-hydroxypropyl)benzofuran 0
                          2-(4-hydroxyphenyl)-5-(E)-propenylbenzofuran 0
                          5-(3-hydroxypropyl)-2-(2-methoxy-4-hydroxyphenyl)benzofuran 0
                          5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen 0
                          8alpha,19-dihydroxylabd-13E-ene-15-oic acid 0
                          LM-1685 6
                          NS-398 95
                          SC-58125 7
                          acetylsalicylic acid + 670
                          agnuside 0
                          alminoprofen 0
                          amfenac + 15
                          amfenac sodium hydrate 0
                          balsaminolate 0
                          bauhinoxepin F 0
                          bauhinoxepin I 0
                          cassiatannin A 0
                          celecoxib 219
                          centaureidin 0
                          cimicoxib 0
                          cinnamtannin B-1 0
                          cinnamtannin D-1 0
                          dehydrocostus lactone 9
                          deracoxib 0
                          dexketoprofen 0
                          etodolac + 30
                          etoricoxib 7
                          fenoprofen 15
                          fenoprofen calcium 0
                          fenoprofen calcium (anhydrous) + 0
                          firocoxib 0
                          fomitopinic acid A 0
                          fomitoside E 0
                          fomitoside F 0
                          gallic acid + 2721
                          ginkgetin 6
                          humulone 0
                          ibuprofen + 308
                          impatienol 0
                          impatienolate 0
                          ipomotaoside A 0
                          ketorolac 21
                          ketorolac tromethamine 12
                          lumiracoxib 16
                          lupulin A 0
                          mallotophilippen C 0
                          mallotophilippen D 0
                          matsudone A 0
                          mavacoxib 0
                          meloxicam 31
                          meso-3,3'-didemethoxynectandrin B 0
                          nabumetone 7
                          naproxen + 108
                          naproxen sodium 0
                          nepafenac 0
                          nimesulide 1252
                          nitroflurbiprofen 7
                          oleocanthal 0
                          paracetamol + 12945
                          parameritannin A-1 0
                          parecoxib 11
                          quercetin 4'-O-alpha-L-rhamnopyranosyl-3-O-beta-D-allopyranoside 0
                          rataniaphenol I 0
                          rataniaphenol II 0
                          rataniaphenol III 0
                          robenacoxib 0
                          rofecoxib 110
                          sodium (2-amino-3-benzoylphenyl)acetate + 0
                          sodium gallate 0
                          sulindac sulfone 51
                          tilmacoxib 0
                          valdecoxib + 733
                          wogonin + 78
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