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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:vorinostat
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Accession:CHEBI:45716 term browser browse the term
Definition:A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Synonyms:exact_synonym: N-hydroxy-N'-phenyloctanediamide
 related_synonym: Formula=C14H20N2O3;   InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18);   InChIKey=WAEXFXRVDQXREF-UHFFFAOYSA-N;   SAHA;   SHH;   SMILES=ONC(=O)CCCCCCC(=O)Nc1ccccc1;   Suberanilohydroxamic acid;   Zolinza;   octanedioic acid hydroxyamide phenylamide;   suberoylanilide hydroxamic acid;   vorinostatum
 xref: CAS:149647-78-9;   DrugBank:DB02546;   Drug_Central:4124;   HMDB:HMDB0015568;   KEGG:D06320;   LINCS:LSM-3828
 xref_mesh: MESH:C111237
 xref: PDBeChem:SHH;   PMID:21657958;   PMID:22887890;   PMID:23320102;   PMID:23348693;   PMID:23708756;   PMID:23758082;   PMID:23820962;   PMID:23864881;   Patent:CN102641261;   Patent:KR20110045493;   Patent:NZ592686;   Patent:US2011039937;   Patent:WO2008106524;   Reaxys:7213017;   Wikipedia:Vorinostat


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      CHEBI ontology 26040
        role 25956
          biological role 25935
            biochemical role 25168
              apoptosis inducer 15003
                vorinostat 2758
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 26040
        subatomic particle 26015
          composite particle 26015
            hadron 26015
              baryon 26015
                nucleon 26015
                  atomic nucleus 26015
                    atom 26015
                      main group element atom 25840
                        p-block element atom 25840
                          carbon group element atom 25437
                            carbon atom 25395
                              organic molecular entity 25395
                                heteroorganic entity 24770
                                  organochalcogen compound 24383
                                    organooxygen compound 24060
                                      carbon oxoacid 22761
                                        carboxylic acid 22741
                                          carboacyl group 20058
                                            univalent carboacyl group 20058
                                              carbamoyl group 19571
                                                carboxamide 19571
                                                  dicarboxylic acid amide 3330
                                                    dicarboxylic acid diamide 2860
                                                      vorinostat 2758
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