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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dextromethorphan
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Accession:CHEBI:4470 term browser browse the term
Definition:A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough.
Synonyms:exact_synonym: (4aS,10S,10aS)-6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene
 related_synonym: (+)-3-methoxy-N-methylmorphinan;   (9alpha,13alpha,14alpha)-3-methoxy-17-methylmorphinan;   3-methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan;   Albutussin;   Antussan;   BA 2666;   Balminil DM;   Benylin DM;   Calmylin;   DXM;   Delsym;   Dextromorphan;   Formula=C18H25NO;   InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1;   InChIKey=MKXZASYAUGDDCJ-NJAFHUGGSA-N;   Medicon;   Romilar;   SMILES=C=1C=2C[C@H]3[C@@]4([C@](C2C=C(C1)OC)(CCCC4)CCN3C)[H];   Tusilan;   d-Methorphan;   destrometerfano;   dextromethorfan;   dextromethorphane;   dextromethorphanum;   dextrometorfano
 alt_id: CHEBI:92579
 xref: CAS:125-71-3;   DrugBank:DB00514;   Drug_Central:842;   HMDB:HMDB0001920;   KEGG:C06947;   KEGG:D03742;   LINCS:LSM-2726
 xref_mesh: MESH:D003915
 xref: PMID:10869398;   PMID:12711372;   PMID:15505150;   PMID:17157116;   PMID:17461892;   PMID:17573115;   PMID:18160193;   PMID:18198471;   PMID:24269965;   PMID:2660263;   PMID:31094746;   PMID:7976530;   PMID:8158182;   PMID:9705419;   Reaxys:88549;   Wikipedia:Dextromethorphan
 cyclic_relationship: is_enantiomer_of CHEBI:146176



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Path 1
Term Annotations click to browse term
  CHEBI ontology 0
    role 0
      biological role 0
        xenobiotic 0
          dextromethorphan 0
            dextromethorphan hydrobromide 0
            racemethorphan 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    p-block element atom 0
                      carbon group element atom 0
                        carbon atom 0
                          organic molecular entity 0
                            heteroorganic entity 0
                              organonitrogen compound 0
                                alkaloid 0
                                  isoquinoline alkaloid 0
                                    morphinane alkaloid 0
                                      6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene 0
                                        dextromethorphan 0
                                          dextromethorphan hydrobromide 0
                                          racemethorphan 0
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