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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:5-fluorouridine
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Accession:CHEBI:40154 term browser browse the term
Definition:An organofluorine compound that is uridine bearing a fluoro substituent at position 5 on the uracil ring.
Synonyms:related_synonym: 5-Fluoro-uridine;   5-Fluorouracil 1beta-D-ribofuranoside;   Formula=C9H11FN2O6;   InChI=1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1;   InChIKey=FHIDNBAQOFJWCA-UAKXSSHOSA-N;   SMILES=OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
 alt_id: CHEBI:46390;   CHEBI:73164
 xref: Beilstein:33662;   CAS:316-46-1;   DrugBank:DB01629;   Gmelin:466575;   KEGG:C16633
 xref_mesh: MESH:C001943
 xref: MetaCyc:CPD0-2367;   PDBeChem:5UD;   PMID:12039627;   PMID:21744792;   Patent:EP1600153;   Patent:EP927045;   Patent:US2005208122;   Patent:US5734042;   Patent:US6372725;   Reaxys:33662


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5-fluorouridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc5 ATP binding cassette subfamily C member 5 increases export ISO ABCC5 protein results in increased export of 5-fluorouridine CTD PMID:15897250 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Sod1 superoxide dismutase 1 affects binding ISO 5-fluorouridine binds to SOD1 protein; 5-fluorouridine binds to SOD1 protein mutant form CTD PMID:23612299 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      biological role 19815
        aetiopathogenetic role 19196
          genotoxin 17673
            mutagen 17592
              5-fluorouridine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            heteroorganic entity 19492
                              organochalcogen compound 19255
                                organooxygen compound 19172
                                  carbohydrates and carbohydrate derivatives 15285
                                    carbohydrate 15285
                                      carbohydrate derivative 14290
                                        glycosyl compound 13048
                                          N-glycosyl compound 5809
                                            nucleoside 5663
                                              ribonucleoside 1129
                                                pyrimidine ribonucleosides 417
                                                  uridines 57
                                                    5-fluorouridine 2
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