CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: flumethrin
Accession: CHEBI:39361
browse the term
Definition: An organofluorine acaricide that has formula C28H22Cl2FNO3.
Synonyms: exact_synonym: cyano(4-fluoro-3-phenoxyphenyl)methyl 3-[2-chloro-2-(4-chlorophenyl)ethenyl]-2,2-dimethylcyclopropanecarboxylate
related_synonym: Formula=C28H22Cl2FNO3; InChI=1S/C28H22Cl2FNO3/c1-28(2)21(15-22(30)17-8-11-19(29)12-9-17)26(28)27(33)35-25(16-32)18-10-13-23(31)24(14-18)34-20-6-4-3-5-7-20/h3-15,21,25-26H,1-2H3; InChIKey=YXWCBRDRVXHABN-UHFFFAOYSA-N; SMILES=CC1(C)C(C=C(Cl)c2ccc(Cl)cc2)C1C(=O)OC(C#N)c1ccc(F)c(Oc2ccccc2)c1
xref: Beilstein:2925940; CAS:69770-45-2
xref_mesh: MESH:C041392
xref: VSDB:1480
G
Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
flumethrin results in increased expression of BAX mRNA
CTD
PMID:34142587
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
flumethrin results in decreased expression of BCL2 mRNA
CTD
PMID:34142587
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
flumethrin results in increased expression of CDKN1A mRNA
CTD
PMID:34142587
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
G
Esr1
estrogen receptor 1
increases expression
ISO
flumethrin results in increased expression of ESR1 mRNA
CTD
PMID:34142587
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Esr2
estrogen receptor 2
increases expression
ISO
flumethrin results in increased expression of ESR2 mRNA
CTD
PMID:34142587
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Pgr
progesterone receptor
increases expression
ISO
flumethrin results in increased expression of PGR mRNA
CTD
PMID:34142587
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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Tff1
trefoil factor 1
increases expression
ISO
flumethrin results in increased expression of TFF1 mRNA
CTD
PMID:34142587
NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
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Tp53
tumor protein p53
increases expression
ISO
flumethrin results in increased expression of TP53 mRNA
CTD
PMID:34142587
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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