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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tenoxicam
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Accession:CHEBI:32192 term browser browse the term
Definition:A thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for the treatment of pain and inflammation in osteoarthritis and rheumatoid arthritis. It is also indicated for short term treatment of acute musculoskeletal disorders including strains, sprains and other soft-tissue injuries.
Synonyms:exact_synonym: 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide
 related_synonym: Formula=C13H11N3O4S2;   InChI=1S/C13H11N3O4S2/c1-16-10(13(18)15-9-4-2-3-6-14-9)11(17)12-8(5-7-21-12)22(16,19)20/h2-7,17H,1H3,(H,14,15,18);   InChIKey=LZNWYQJJBLGYLT-UHFFFAOYSA-N;   Mobiflex;   SMILES=CN1C(C(=O)Nc2ccccn2)=C(O)c2sccc2S1(=O)=O;   Tilcotil;   tenoxicamum
 xref: CAS:59804-37-4;   DrugBank:DB00469;   Drug_Central:2595;   KEGG:D01767
 xref_mesh: MESH:C032801
 xref: PMID:21129461;   PMID:21327813;   PMID:21682312;   PMID:21712619;   PMID:21777594;   PMID:21929527;   PMID:21981557;   PMID:22095696;   PMID:22182582;   PMID:22306394;   PMID:22675955;   PMID:22841852;   PMID:22876956;   PMID:23204620;   PMID:23273940;   PMID:23340327;   PMID:23480456;   PMID:23656309;   PMID:23932198;   PMID:24037655;   PMID:24093711;   PMID:28166217;   Patent:US2008014272;   Patent:US4687766;   Reaxys:572193;   Wikipedia:Tenoxicam


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tenoxicam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a8 solute carrier family 22 member 8 multiple interactions ISO tenoxicam inhibits the reaction [SLC22A8 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:15100168 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      application 19627
        anti-inflammatory agent 16580
          anti-inflammatory drug 14922
            non-steroidal anti-inflammatory drug 14237
              tenoxicam 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbon oxoacid 18612
                                    carboxylic acid 18609
                                      carboacyl group 17677
                                        univalent carboacyl group 17677
                                          carbamoyl group 17526
                                            carboxamide 17526
                                              monocarboxylic acid amide 15662
                                                tenoxicam 1
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