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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:benazepril
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Accession:CHEBI:3011 term browser browse the term
Definition:A benzazepine that is benazeprilat in which the carboxy group of the 2-amino-4-phenylbutanoic acid moiety has been converted to the corresponding ethyl ester. It is used (generally as its hydrochloride salt) as a prodrug for the angiotensin-converting enzyme inhibitor benazeprilat in the treatment of hypertension and heart failure.
Synonyms:exact_synonym: [(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
 related_synonym: 1H-1-Benzazepine-1-acetic acid, 3-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-2,3,4,5-tetrahydro-2-oxo-, (S-(R*,R*))-;   Formula=C24H28N2O5;   InChI=1S/C24H28N2O5/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28)/t19-,20-/m0/s1;   InChIKey=XPCFTKFZXHTYIP-PMACEKPBSA-N;   SMILES=CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CCc2ccccc2N(CC(O)=O)C1=O;   benazeprilum
 xref: CAS:86541-75-5;   DrugBank:DB00542;   Drug_Central:299;   HMDB:HMDB0014682;   KEGG:C06843;   KEGG:D07499;   LINCS:LSM-5609
 xref_mesh: MESH:C044946
 xref: MetaCyc:CPD-15329;   PMID:25224804;   PMID:25738503;   PMID:25784709;   PMID:25912588;   Patent:EP72352;   Patent:US4410520;   Reaxys:4302258;   Wikipedia:Benazepril
 cyclic_relationship: is_conjugate_base_of CHEBI:88201


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Term Annotations click to browse term
  CHEBI ontology 0
    role 0
      application 0
        pro-agent 0
          prodrug 0
            benazepril 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    p-block element atom 0
                      carbon group element atom 0
                        carbon atom 0
                          organic molecular entity 0
                            heteroorganic entity 0
                              organochalcogen compound 0
                                organooxygen compound 0
                                  carbon oxoacid 0
                                    carboxylic acid 0
                                      carboacyl group 0
                                        univalent carboacyl group 0
                                          carbamoyl group 0
                                            carboxamide 0
                                              lactam 0
                                                benazeprilat 0
                                                  benazepril 0
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