Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:MJN110
go back to main search page
Accession:CHEBI:228388 term browser browse the term
Synonyms:exact_synonym: (2,5-dioxopyrrolidin-1-yl) 4-[bis(4-chlorophenyl)methyl]piperazine-1-carboxylate
 related_synonym: Formula=C22H21Cl2N3O4;   InChI=1S/C22H21Cl2N3O4/c23-17-5-1-15(2-6-17)21(16-3-7-18(24)8-4-16)25-11-13-26(14-12-25)22(30)31-27-19(28)9-10-20(27)29/h1-8,21H,9-14H2;   InChIKey=BEADRWVIFHOSGN-UHFFFAOYSA-N;   SMILES=ClC1=CC=C(C(N2CCN(CC2)C(ON3C(=O)CCC3=O)=O)C4=CC=C(Cl)C=C4)C=C1
 xref: Chemspider:34975859;   HMDB:HMDB0254772;   KEGG:D81272
 xref_mesh: MESH:C587715


show annotations for term's descendants           Sort by:
MJN110 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg5 autophagy related 5 multiple interactions ISO ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of CCL2 protein]]; ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL1A protein]]; ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL1B protein]]; ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL6 protein]] CTD PMID:30301768 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of CCL2 protein]]; MJN110 affects the reaction [Lipopolysaccharides affects the secretion of CCL2 protein] CTD PMID:30301768 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL1A protein]]; MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL1A protein] CTD PMID:30301768 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL1B protein]]; MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL1B protein] CTD PMID:30301768 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO ATG5 protein affects the reaction [MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL6 protein]]; MJN110 affects the reaction [Lipopolysaccharides affects the secretion of IL6 protein] CTD PMID:30301768 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions
increases lipidation		 ISO MJN110 affects the reaction [Chloroquine results in increased lipidation of MAP1LC3B protein]
MJN110 results in increased lipidation of MAP1LC3B protein		 CTD PMID:30301768 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Mgll monoglyceride lipase multiple interactions
decreases activity		 ISO [MJN110 results in decreased activity of MGLL protein] which results in decreased hydrolysis of and results in increased abundance of glyceryl 2-arachidonate CTD PMID:26791602 PMID:27307500 NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19844
    chemical entity 19842
      group 19800
        polyatomic entity 19799
          molecule 19702
            cyclic compound 19516
              organic cyclic compound 19498
                organic aromatic compound 19366
                  diarylmethane 9439
                    MJN110 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19844
    subatomic particle 19842
      composite particle 19842
        hadron 19842
          baryon 19842
            nucleon 19809
              atomic nucleus 19842
                atom 19842
                  main group element atom 19792
                    p-block element atom 19792
                      p-block molecular entity 19792
                        carbon group molecular entity 19738
                          organic molecular entity 19734
                            organic molecule 19687
                              organic cyclic compound 19498
                                organic aromatic compound 19366
                                  diarylmethane 9439
                                    MJN110 7
paths to the root