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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cobamamide
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Accession:CHEBI:18408 term browser browse the term
Definition:A member of the class of cobalamins that is vitamin B12 in which the cyano group is replaced by a 5'-deoxyadenos-5'-yl moiety. It is one of the two metabolically active form of vitamin B12.
Synonyms:exact_synonym: Coalpha-[alpha-(5,6-dimethylbenzimidazolyl)]-Cobeta-(5'-deoxy-5'-adenosyl)cobamide
 related_synonym: (5,6-dimethylbenzimidazolyl)cobamide coenzyme;   5'-Deoxy-5'-adenosyl vitamin B12;   5'-Deoxy-5'-adenosyl-5,6-dimethylbenzimidazolylcobamide;   5'-Deoxy-5'-adenosylcobalamin;   5'-deoxyadenosyl vitamin B12;   5'-deoxyadenosyl-5,6-dimethylbenzimidazolylcobamide;   5'-deoxyadenosylcobalamin;   5,6-Dimethylbenzimidazolyl-5-deoxyadenosyl-cobamide;   5,6-Dimethylbenzimidazolyl-Co-5'-deoxy-5'-adenosylcobamide;   Adenosylcob(III)alamin;   AdoCbl;   Calomide;   Coalpha-[alpha-(5,6-dimethylbenzimidazolyl)]-Cobeta-adenosylcobamide;   Cobalamin coenzyme;   Coenzyme B12;   DBC coenzyme;   DMBC coenzyme;   Deoxyadenosylcobalamin;   Dibencozide;   Formula=C72H100CoN18O17P;   Funacomide;   InChI=1S/C62H90N13O14P.C10H12N5O3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);2-4,6-7,10,16-17H,1H2,(H2,11,12,13);/q;;+2/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56-,57+,59-,60+,61+,62+;4-,6-,7-,10-;/m11./s1;   InChIKey=ZIHHMGTYZOSFRC-OUCXYWSSSA-L;   SMILES=[H][C@]12[C@H](CC(N)=O)[C@@]3(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@@H]4[C@@H](CO)O[C@@H]([C@@H]4O)n4c[n+](c5cc(C)c(C)cc45)[Co-3]456(C[C@H]7O[C@H]([C@H](O)[C@@H]7O)n7cnc8c(N)ncnc78)N1C3=C(C)C1=[N+]4C(=CC3=[N+]5C(=C(C)C4=[N+]6[C@]2(C)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)[C@@](C)(CC(N)=O)[C@@H]3CCC(N)=O)C(C)(C)[C@@H]1CCC(N)=O;   Vitamin B12 coenzyme;   adenosylcobalamin;   alpha-(5,6-Dimethylbenzimidazolyl)cobamide coenzyme;   cobamamid;   cobamamida;   cobamamidum;   cobamide coenzyme;   coenzyme B-12
 alt_id: CHEBI:13739;   CHEBI:23340;   CHEBI:3797
 xref: Beilstein:4122932;   CAS:13870-90-1;   DrugBank:DB11191;   Gmelin:439994;   HMDB:HMDB0002086;   KEGG:C00194
 xref_mesh: MESH:C000913
 xref: MetaCyc:ADENOSYLCOBALAMIN;   PDBeChem:B1Z;   PMID:11792214;   PMID:12093296;   PMID:17011224;   Reaxys:4122932;   Wikipedia:Cobamamide


show annotations for term's descendants           Sort by:
cobamamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO cobamamide inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      biological role 19782
        biochemical role 19496
          cofactor 16151
            cobamamide 1
              adenosylcobalamin 5'-phosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            organic molecule 19655
                              organic cyclic compound 19468
                                organic heterocyclic compound 18848
                                  organonitrogen heterocyclic compound 18126
                                    polypyrrole 698
                                      tetrapyrrole 585
                                        cyclic tetrapyrrole 455
                                          metallotetrapyrrole 420
                                            cobalt corrinoid 110
                                              cobalt-corrinoid hexaamide 110
                                                cobamides 110
                                                  cobalamins 110
                                                    cobamamide 1
                                                      adenosylcobalamin 5'-phosphate 0
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