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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:14-demethyllanosterol
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Accession:CHEBI:18364 term browser browse the term
Definition:A 3beta-sterol formed formally by loss of a methyl group from the 14-position of lanosterol.
Synonyms:related_synonym: (3beta,5alpha)-4,4-dimethylcholesta-8,24-dien-3-ol;   14-desmethyllanosterol;   4,4-Dimethyl-5alpha-cholesta-8,24-dien-3beta-ol;   4,4-Dimethyl-8,24-cholestadienol;   4,4-dimethylcholesta-8(9),24-dien-3beta-ol;   4,4-dimethylzymosterol;   Formula=C29H48O;   InChI=1S/C29H48O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,20,22-23,25-26,30H,8,10-18H2,1-7H3/t20-,22-,23+,25+,26+,28-,29-/m1/s1;   InChIKey=CHGIKSSZNBCNDW-QGBOJXOESA-N;   SMILES=C12=C([C@]3([C@]([C@](CC3)([C@@H](CCC=C(C)C)C)[H])(C)CC1)[H])CC[C@@]4([C@@]2(CC[C@@H](C4(C)C)O)C)[H]
 alt_id: CHEBI:11921;   CHEBI:19151;   CHEBI:755
 xref: Beilstein:2302110;   CAS:7448-02-4;   KEGG:C05108;   KNApSAcK:C00023776
 xref_mesh: MESH:C013499
 xref: Reaxys:2302110


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14-demethyllanosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Msmo1 methylsterol monooxygenase 1 decreases abundance ISO MSMO1 protein results in decreased abundance of 4,4-dimethyl-5-alpha-cholesta-(8,24)-dien-3-beta-ol CTD PMID:23125191 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      biological role 19782
        biochemical role 19496
          metabolite 19484
            eukaryotic metabolite 19307
              plant metabolite 17943
                lanosterol 7
                  14-demethyllanosterol 1
                    4beta-hydroxymethyl-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            organic molecule 19655
                              organic cyclic compound 19468
                                organic polycyclic compound 17225
                                  steroid 14678
                                    hydroxy steroid 14425
                                      3-hydroxy steroid 12764
                                        sterol 463
                                          3beta-sterol 457
                                            lanosterol 7
                                              14-demethyllanosterol 1
                                                4beta-hydroxymethyl-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 0
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