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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:PD-146176
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Accession:CHEBI:173098 term browser browse the term
Definition:An organic heterotetracyclic compound that is 1H-indole which is ortho-fused to a 2H-1-benzothiopyran group at positions 2-3. It is an inhibitor of 15-lipoxygenase that limits atherosclerotic lesion development in rabbits.
Synonyms:exact_synonym: 6,11-dihydrothiochromeno[4,3-b]indole
 related_synonym: 6,11-dihydro[1]benzothiopyrano[4,3-b]indole;   Formula=C15H11NS;   InChI=1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2;   InChIKey=ZGOOPZVQMLHPFM-UHFFFAOYSA-N;   PD146176;   SMILES=C1SC2=CC=CC=C2C2=C1C1=C(N2)C=CC=C1
 xref: CAS:4079-26-9;   PMID:15713402;   PMID:17378609;   PMID:21619415;   PMID:23382512;   PMID:25560760;   PMID:26040494;   PMID:26331552;   PMID:27477687;   PMID:27499089;   PMID:29546268;   PMID:30964295;   PMID:32945449;   PMID:9105693;   PMID:9543090


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Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      biological role 19815
        inhibitor 18907
          ferroptosis inhibitor 8054
            PD-146176 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            organic molecule 19686
                              organic cyclic compound 19498
                                organic heterocyclic compound 18876
                                  organic heteropolycyclic compound 18301
                                    organic heterotetracyclic compound 9220
                                      PD-146176 0
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