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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2'-deoxyadenosine
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Accession:CHEBI:17256 term browser browse the term
Definition:A purine 2'-deoxyribonucleoside having adenine as the nucleobase.
Synonyms:related_synonym: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol;   5-(6-AMINO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-OL;   9-(2-Deoxy-beta-D-erythro-pentofuranosyl)adenine;   9-(2-deoxy-beta-D-ribofuranosyl)-9H-purin-6-amine;   Deoxyadenosine;   Formula=C10H13N5O3;   InChI=1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1;   InChIKey=OLXZPDWKRNYJJZ-RRKCRQDMSA-N;   SMILES=Nc1ncnc2n(cnc12)[C@H]1C[C@H](O)[C@@H](CO)O1;   adenine deoxyribonucleoside;   adenyldeoxyriboside;   dA
 alt_id: CHEBI:14112;   CHEBI:19234;   CHEBI:39863;   CHEBI:40535;   CHEBI:40560;   CHEBI:4405
 xref: Beilstein:91015;   CAS:958-09-8;   Gmelin:283189;   HMDB:HMDB0000101;   KEGG:C00559;   KNApSAcK:C00019281
 xref_mesh: MESH:C058118
 xref: MetaCyc:DEOXYADENOSINE;   PDBeChem:3D1;   PMID:14253484;   PMID:18508186;   PMID:24144081;   PMID:8171392;   PMID:9869364;   Reaxys:91015;   Wikipedia:Deoxyadenosine


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2'-deoxyadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO 2'-deoxyadenosine results in decreased expression of CDKN1A mRNA CTD PMID:24211769 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Polb DNA polymerase beta multiple interactions ISO [diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLB protein CTD PMID:26098310 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812 		JBrowse link
G Poli DNA polymerase iota multiple interactions ISO [diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLI protein; POLN protein inhibits the reaction [[diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLI protein] CTD PMID:26098310 NCBI chr18:64,116,774...64,134,373
Ensembl chr18:64,116,774...64,163,418 		JBrowse link
G Polk DNA polymerase kappa multiple interactions ISO [diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLK protein CTD PMID:26098310 NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313 		JBrowse link
G Poln DNA polymerase nu multiple interactions ISO [diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLN protein; POLN protein inhibits the reaction [[diepoxybutane binds to 2'-deoxyadenosine] which results in decreased activity of POLI protein] CTD PMID:26098310 NCBI chr14:76,579,983...76,752,460
Ensembl chr14:76,580,546...76,752,463 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 multiple interactions ISO 2'-deoxyadenosine inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine] CTD PMID:11085929 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203 		JBrowse link
G Slc29a2 solute carrier family 29 member 2 multiple interactions ISO 2'-deoxyadenosine inhibits the reaction [SLC29A2 protein results in increased uptake of Uridine] CTD PMID:11085929 NCBI chr 1:202,327,641...202,335,185
Ensembl chr 1:202,327,354...202,335,171 		JBrowse link
8,5'-cyclo-2'-deoxyadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neil1 nei-like DNA glycosylase 1 affects metabolic processing ISO NEIL1 protein affects the metabolism of 8,5'-cyclo-2'-deoxyadenosine CTD PMID:20067321 NCBI chr 8:57,550,142...57,556,884
Ensembl chr 8:57,550,147...57,556,258 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    chemical entity 19806
      atom 19806
        nonmetal atom 19744
          carbon atom 19702
            organic molecular entity 19702
              purines 2'-deoxy-D-ribonucleoside 14
                2'-deoxyadenosine 8
                  8,5'-cyclo-2'-deoxyadenosine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbohydrates and carbohydrate derivatives 15270
                                    carbohydrate 15270
                                      carbohydrate derivative 14278
                                        glycosyl compound 13035
                                          N-glycosyl compound 5806
                                            nucleoside 5660
                                              deoxyribonucleoside 2880
                                                2'-deoxyribonucleoside 2246
                                                  purine 2'-deoxyribonucleoside 34
                                                    purines 2'-deoxy-D-ribonucleoside 14
                                                      2'-deoxyadenosine 8
                                                        8,5'-cyclo-2'-deoxyadenosine 1
paths to the root