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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:CDN1163
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Accession:CHEBI:150005 term browser browse the term
Definition:A secondary carboxamide resulting from the formal condensation of the carboxy group of 4-isopropoxybenzoic acid with the primary amino group of 2-methylquinolin-8-amine. An allosteric activator of sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA).
Synonyms:exact_synonym: N-(2-methylquinolin-8-yl)-4-(propan-2-yloxy)benzamide
 related_synonym: 4-(1-methylethoxy)-N-(2-methyl-8-quinolinyl)-benzamide;   CDN-1163;   Formula=C20H20N2O2;   InChI=1S/C20H20N2O2/c1-13(2)24-17-11-9-16(10-12-17)20(23)22-18-6-4-5-15-8-7-14(3)21-19(15)18/h4-13H,1-3H3,(H,22,23);   InChIKey=GVGVYDCVFBGALZ-UHFFFAOYSA-N;   SMILES=O=C(NC1=C2N=C(C=CC2=CC=C1)C)C3=CC=C(OC(C)C)C=C3
 xref: CAS:892711-75-0
 xref_mesh: MESH:C000609635
 xref: PMCID:PMC6227549;   PMID:26702054;   PMID:27776889;   PMID:29602679;   PMID:30296699;   PMID:30353146;   PMID:32007101


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CDN1163 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mttp microsomal triglyceride transfer protein multiple interactions ISO CDN1163 inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MTTP protein] CTD PMID:34516972 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      biological role 19782
        activator 107
          enzyme activator 68
            SERCA activator 1
              CDN1163 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbon oxoacid 18612
                                    carboxylic acid 18609
                                      carboacyl group 17677
                                        univalent carboacyl group 17677
                                          carbamoyl group 17526
                                            carboxamide 17526
                                              secondary carboxamide 1219
                                                CDN1163 1
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