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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:8-epi-prostaglandin E2
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Accession:CHEBI:131888 term browser browse the term
Definition:A prostanoid that is prostaglandin E2 having inverted stereochemistry at the 8-position.
Synonyms:exact_synonym: (5Z,8beta,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
 related_synonym: 7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic acid;   8-epi-PGE2;   8-iso-PGE2;   8-isoprostaglandin E2;   Formula=C20H32O5;   InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16-,17+,19+/m0/s1;   InChIKey=XEYBRNLFEZDVAW-CLQOMRTCSA-N;   SMILES=C(\\[C@H]1[C@@H](CC([C@H]1C/C=C\\CCCC(O)=O)=O)O)=C/[C@H](CCCCC)O
 xref: CAS:27415-25-4;   Chemspider:4446334;   HMDB:HMDB0005844;   LIPID_MAPS_instance:LMFA03110003
 xref_mesh: MESH:C011987
 xref: PMID:10636418;   PMID:10718110;   PMID:11160628;   PMID:12376370;   PMID:12626646;   PMID:12716476;   PMID:12869634;   PMID:15257985;   PMID:17690331;   PMID:19088946;   PMID:19513831;   PMID:20036885;   PMID:22015024;   PMID:22565502;   PMID:22959706;   PMID:26209241;   PMID:9013211;   PMID:9099206;   PMID:9316826;   Reaxys:4709355


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8-epi-prostaglandin E2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger4 prostaglandin E receptor 4 affects response to substance ISO PTGER4 protein affects the susceptibility to 8-isoprostaglandin E2 CTD PMID:22565502 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      application 19627
        pharmaceutical 19468
          drug 19468
            bronchoconstrictor agent 67
              8-epi-prostaglandin E2 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbon oxoacid 18612
                                    carboxylic acid 18609
                                      monocarboxylic acid 17984
                                        fatty acid 16792
                                          fatty acid derivative 8960
                                            icosanoid 470
                                              prostanoid 406
                                                prostaglandin 399
                                                  prostaglandins E 236
                                                    prostaglandin E2 233
                                                      8-epi-prostaglandin E2 1
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