|
.0 |
.475 |
.992 |
.07 |
.0 |
.0 |
.828 |
.063 |
.036 |
.024 |
.017 |
.215 |
-- |
1.0 |
1.0 |
.982 |
.199 |
.681 |
.006 |
.013 |
.031 |
.222 |
.253 |
.125 |
.027 |
.912 |
.086 |
.087 |
.115 |
.001 |
.006 |
.816 |
.002 |
.128 |
.065 |
.01 |
.012 |
.005 |
.015 |
-- |
-- |
.671 |
.003 |
.0 |
.008 |
.036 |
.004 |
.005 |
.001 |
.0 |
.0 |
.643 |
-- |
-- |
-- |
.09 |
.006 |
.001 |
.011 |
.0 |
.154 |
.151 |
.058 |
.025 |
.004 |
.002 |
.0 |
.011 |
.013 |
.065 |
.017 |
.004 |
.303 |
.11 |
.217 |
.09 |
.389 |
-- |
-- |
.022 |
.0 |
.002 |
1.0 |
.191 |
.139 |
.975 |
.132 |
.001 |
.023 |
.01 |
.301 |
.0 |
-- |
.053 |
.008 |
-- |
-- |
-- |
-- |
.016 |
-- |
.0 |
.154 |
1.0 |
.044 |
|
Smad2
|
Smad2
|
Smad2
|
Smad2
|
Smad2
|
Smad2
|
Smad2
|
Smad2
|
Smad2
|
Smad2
|
Smad2
|
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
A |
A |
G |
T |
A |
C |
A |
A |
T |
T |
2 |
G |
G |
G |
G |
T |
T |
C |
T |
C |
G |
C |
2 |
T |
12 |
T |
T |
T |
7 |
G |
C |
5 |
G |
T |
A |
C |
C |
A |
C |
C |
A |
C |
T |
T |
T |
G |
T |
A |
G |
G |
C |
G |
A |
G |
12 |
T |
G |
A |
C |
C |
2 |
T |
A |
G |
A |
G |
G |
T |
G |
C |
G |
A |
T |
A |
C |
12 |
T |
G |
C |
A |
5 |
G |
A |
C |
G |
T |
A |
A |
A |
C |
G |
C |
A |
G |
G |
A |
G |
A |
2 |
G |
C |
C |
C |
T |
A |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
T
|
G
|
A
|
C
|
G
|
T
|
C
|
T
|
-
|
A
|
-
|
A
|
G/C
|
A
|
T
|
A
|
C
|
T
|
C
|
T
|
T
|
T
|
-
|
C
|
-
|
A
|
-
|
A
|
-
|
A
|
-
|
-
|
C
|
-
|
T
|
G
|
G
|
G
|
T
|
A
|
T
|
-
|
A
|
C
|
C
|
A
|
G
|
T
|
A
|
A
|
T
|
T
|
G
|
A
|
-
|
-
|
A
|
3
|
-
|
T
|
-
|
C
|
G
|
A
|
T
|
A
|
T
|
2
|
T
|
T
|
T
|
T
|
G
|
G
|
T
|
-
|
G
|
A
|
T
|
G
|
-
|
A
|
-
|
T
|
T
|
C
|
G
|
G
|
T
|
T
|
A
|
-
|
-
|
A
|
C
|
G
|
A
|
G
|
-
|
A
|
A
|
T
|
G
|
C
|
G
|
|