|
.019 |
.0 |
.901 |
.081 |
.0 |
.394 |
.002 |
.009 |
.0 |
.007 |
.002 |
.001 |
.135 |
.12 |
.084 |
.01 |
.001 |
.001 |
.001 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.0 |
.114 |
.005 |
.0 |
.054 |
.131 |
.001 |
.998 |
.126 |
.0 |
.007 |
.007 |
.015 |
.004 |
.001 |
.024 |
.084 |
.004 |
-- |
-- |
-- |
.015 |
.008 |
.0 |
.002 |
.0 |
.068 |
-- |
.005 |
.274 |
.0 |
.052 |
.407 |
.022 |
.21 |
.002 |
.002 |
.108 |
.003 |
.001 |
.075 |
.001 |
.272 |
.014 |
.694 |
.002 |
-- |
-- |
-- |
-- |
-- |
.007 |
.003 |
.0 |
.003 |
.001 |
.0 |
.0 |
.002 |
.006 |
.001 |
.027 |
.004 |
.126 |
.008 |
.002 |
.002 |
.0 |
.001 |
.002 |
.001 |
.003 |
.001 |
.001 |
.0 |
.0 |
.001 |
.002 |
.0 |
.008 |
.144 |
-- |
-- |
-- |
.041 |
.0 |
.053 |
.017 |
.238 |
.0 |
.033 |
.024 |
.049 |
-- |
-- |
.001 |
.001 |
.957 |
.021 |
.001 |
.002 |
.002 |
.046 |
.126 |
-- |
.001 |
.755 |
.012 |
-- |
.003 |
.0 |
.001 |
.007 |
.027 |
.39 |
.061 |
.028 |
.003 |
.005 |
.043 |
.04 |
.012 |
.109 |
.038 |
.028 |
.861 |
.003 |
.001 |
.061 |
.003 |
-- |
-- |
.001 |
.001 |
.0 |
.005 |
.015 |
.059 |
.075 |
.001 |
.006 |
.162 |
.023 |
.104 |
.002 |
.248 |
.053 |
.004 |
.275 |
.131 |
.498 |
.121 |
.007 |
.001 |
.003 |
.001 |
.003 |
.345 |
.002 |
.0 |
.004 |
.74 |
.942 |
.945 |
.522 |
.102 |
.03 |
.008 |
.025 |
.259 |
.029 |
.078 |
-- |
-- |
-- |
-- |
-- |
.005 |
.335 |
.047 |
.046 |
.839 |
.9 |
.113 |
.388 |
.806 |
.003 |
.092 |
.094 |
.04 |
.018 |
.017 |
.036 |
.039 |
.009 |
.083 |
.08 |
.364 |
.366 |
.505 |
.003 |
.037 |
.013 |
.057 |
.089 |
.005 |
.036 |
.084 |
.009 |
.105 |
.013 |
.0 |
.006 |
.123 |
.006 |
.002 |
.101 |
.016 |
.001 |
.225 |
.016 |
.01 |
.085 |
.001 |
.005 |
.002 |
.145 |
.004 |
.071 |
-- |
-- |
-- |
-- |
.0 |
.003 |
.997 |
.001 |
.006 |
.918 |
.055 |
.114 |
.174 |
.214 |
.034 |
.001 |
.0 |
.001 |
.0 |
.001 |
.009 |
.027 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.004 |
.043 |
.67 |
.019 |
.0 |
.001 |
.006 |
.014 |
.013 |
.311 |
.001 |
.008 |
.066 |
.0 |
.04 |
.101 |
.058 |
.026 |
-- |
.018 |
.361 |
.183 |
.003 |
.002 |
.0 |
.0 |
.0 |
.0 |
.001 |
.692 |
.05 |
.015 |
.012 |
.001 |
.02 |
.002 |
.005 |
.002 |
.0 |
.0 |
.001 |
.036 |
.026 |
.001 |
.191 |
.017 |
.287 |
.293 |
.005 |
.75 |
.069 |
.142 |
.809 |
.37 |
.072 |
.071 |
.001 |
.31 |
.039 |
.015 |
.011 |
.008 |
.014 |
-- |
-- |
.039 |
.004 |
.946 |
-- |
-- |
-- |
-- |
.02 |
.003 |
-- |
.857 |
.854 |
.001 |
.408 |
.544 |
-- |
-- |
-- |
.456 |
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
Plcb1
|
|
--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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|
--
|
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|
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|
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|
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|
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|
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|
--
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--
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|
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|
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|
--
|
--
|
--
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--
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--
|
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|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
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|
--
|
--
|
--
|
--
|
--
|
--
|
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|
--
|
--
|
--
|
--
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--
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--
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|
--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
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--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
A |
T |
C |
T |
T |
A |
C |
C |
2 |
T |
A |
A |
G |
G |
A |
G |
T |
C |
3 |
T |
2 |
2 |
T |
C |
3 |
G |
G |
G |
A |
C |
2 |
T |
G |
T |
G |
6 |
G |
T |
2 |
C |
A |
3 |
T |
C |
C |
2 |
2 |
T |
T |
T |
C |
T |
G |
G |
2 |
G |
G |
T |
C |
T |
G |
2 |
T |
A |
T |
4 |
2 |
C |
6 |
2 |
2 |
T |
G |
C |
G |
C |
C |
C |
G |
C |
T |
C |
T |
T |
T |
C |
G |
A |
C |
G |
A |
G |
A |
G |
G |
G |
G |
G |
C |
G |
C |
C |
G |
C |
G |
G |
G |
5 |
A |
G |
C |
A |
C |
2 |
G |
A |
G |
2 |
T |
G |
6 |
G |
A |
G |
A |
G |
A |
G |
C |
C |
G |
G |
2 |
T |
14 |
A |
2 |
2 |
4 |
A |
3 |
T |
C |
T |
5 |
T |
T |
G |
3 |
4 |
3 |
G |
A |
C |
G |
T |
2 |
C |
A |
T |
9 |
T |
A |
A |
A |
T |
A |
G |
T |
C |
T |
T |
T |
T |
T |
C |
G |
A |
A |
G |
G |
G |
C |
T |
12 |
G |
C |
T |
A |
A |
G |
G |
C |
T |
G |
G |
C |
A |
T |
T |
C |
A |
C |
A |
C |
6 |
2 |
A |
A |
T |
T |
G |
T |
C |
T |
A |
4 |
A |
G |
T |
T |
A |
G |
T |
T |
C |
G |
T |
G |
G |
T |
G |
T |
A |
G |
A |
A |
A |
G |
G |
T |
G |
A |
3 |
G |
A |
G |
A |
T |
2 |
15 |
C |
T |
G |
T |
C |
T |
G |
C |
T |
T |
14 |
12 |
A |
A |
A |
16 |
C |
A |
C |
G |
A |
C |
T |
G |
G |
A |
G |
C |
T |
C |
8 |
A |
C |
A |
G |
2 |
G |
G |
T |
A |
T |
C |
4 |
A |
T |
T |
4 |
2 |
A |
A |
T |
C |
C |
C |
A |
A |
C |
C |
T |
A |
T |
T |
G |
C |
C |
G |
C |
T |
G |
A |
G |
T |
G |
G |
G |
T |
T |
C |
T |
T |
A |
A |
G |
2 |
A |
C |
A |
A |
T |
C |
C |
C |
G |
A |
C |
2 |
2 |
2 |
2 |
A |
A |
4 |
A |
4 |
4 |
3 |
G |
G |
T |
T |
G |
8 |
4 |
A |
C |
A |
A |
G |
2 |
G |
2 |
C |
G |
4 |
2 |
C |
18 |
2 |
72 |
G |
G |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
G
|
C
|
T
|
C
|
A
|
T
|
4
|
7
|
-
|
C
|
53
|
10
|
-
|
-
|
-
|
-
|
-
|
A
|
-
|
A
|
-
|
-
|
3
|
-
|
-
|
-
|
-
|
-
|
A/C
|
7
|
2/-
|
5/9
|
C
|
C
|
T
|
-
|
G/-
|
A
|
-
|
A
|
T
|
-
|
4
|
?
|
2
|
2/-
|
2/-
|
2
|
G
|
T/-
|
3
|
2
|
3/5
|
G/C
|
-
|
A
|
2
|
3
|
C/7
|
3
|
G/3
|
-
|
5/3
|
C
|
T/5
|
4/-
|
2/-
|
T
|
6/-
|
2/-
|
-
|
A
|
9
|
T
|
3/4
|
3
|
-
|
A
|
T
|
-
|
A
|
G
|
G
|
A
|
C
|
T
|
T
|
T
|
T
|
T
|
T
|
C
|
T
|
T
|
C
|
C
|
A
|
T
|
A
|
A
|
T
|
A
|
-
|
T
|
A
|
C
|
G/25
|
-
|
5
|
2
|
3
|
3
|
-
|
2/-
|
29
|
-
|
GT/3
|
2/-
|
T/3
|
G/-
|
-
|
C
|
G
|
G/5
|
A/-
|
2
|
-
|
-
|
C/A
|
C/A
|
-
|
2
|
2/-
|
-
|
14/-
|
G
|
-
|
2/-
|
-
|
41
|
-
|
A
|
C/4
|
T/-
|
-
|
C
|
A
|
A
|
-
|
-
|
3/-
|
A
|
C
|
A
|
2
|
C
|
-
|
A
|
T
|
G
|
-
|
G
|
G
|
G
|
G
|
C
|
C
|
A
|
2
|
2
|
C
|
A
|
G
|
G
|
C
|
A
|
C
|
C
|
G
|
C
|
2
|
A
|
A
|
C
|
-
|
T
|
A
|
G
|
G
|
C
|
A
|
A
|
6
|
20
|
2
|
A
|
T
|
G
|
C
|
C
|
T
|
G
|
9
|
G
|
T
|
-
|
-
|
2
|
G
|
A
|
C
|
A
|
C
|
A
|
G
|
G
|
-
|
G
|
T
|
C
|
-
|
-
|
A
|
C
|
C
|
T
|
A
|
C
|
2
|
A
|
C
|
A
|
C
|
C
|
T
|
G
|
G
|
2
|
2
|
2
|
G
|
T
|
G
|
-
|
C
|
C
|
A
|
G
|
C
|
-
|
-
|
16
|
C
|
C
|
C
|
T
|
C
|
T
|
T
|
C
|
2
|
14/-
|
12/-
|
G
|
G
|
G
|
-
|
T
|
G
|
T
|
A
|
G
|
T
|
51
|
8
|
T
|
G
|
C
|
T
|
G
|
2
|
-
|
G
|
A
|
-
|
2
|
-
|
2
|
-
|
C
|
G
|
A
|
T
|
-
|
G
|
C
|
C
|
4/-
|
2/-
|
G
|
G
|
C
|
21
|
T
|
T
|
G
|
G
|
G
|
4
|
A
|
-
|
-
|
A
|
A
|
T
|
T
|
A
|
G
|
C
|
A
|
T
|
A
|
C
|
A
|
C
|
A
|
C
|
C
|
A
|
G
|
A
|
2
|
21
|
A
|
-
|
T
|
A
|
G
|
G
|
C
|
T
|
T
|
3/CT
|
T
|
G
|
C/2
|
2/-
|
2/-
|
2/-
|
2/-
|
-
|
3
|
-
|
32
|
-
|
4/-
|
3/-
|
2
|
T
|
C
|
11
|
62
|
8/-
|
4/-
|
G
|
G
|
G
|
?
|
A
|
2/-
|
G/6
|
2/-
|
2
|
G/7
|
4/-
|
2/-
|
A
|
18/-
|
2/-
|
-
|
2
|
2
|
2/-
|
|