Or7g12 (olfactory receptor family 7 subfamily G member 12) - Rat Genome Database

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Gene: Or7g12 (olfactory receptor family 7 subfamily G member 12) Rattus norvegicus
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Symbol: Or7g12
Name: olfactory receptor family 7 subfamily G member 12
RGD ID: 1333031
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR7G3 (olfactory receptor family 7 subfamily G member 3); INTERACTS WITH bisphenol A; copper atom; copper(0).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1125; olfactory receptor gene Olr1125; olfactory receptor Olr1125; Olr1125
RGD Orthologs
Human
Mouse
Bonobo
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8824,850,668 - 24,851,606 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl824,850,668 - 24,851,606 (+)EnsemblGRCr8
mRatBN7.2816,574,372 - 16,575,310 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl816,574,372 - 16,575,310 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx820,559,065 - 20,560,003 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0818,856,902 - 18,857,840 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0816,788,984 - 16,789,922 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0818,845,579 - 18,846,517 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl818,845,579 - 18,846,517 (+)Ensemblrn6Rnor6.0
Rnor_5.0818,913,855 - 18,914,793 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4816,972,165 - 16,973,103 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera817,991,828 - 17,992,766 (+)NCBICelera
RGSC_v3.1816,972,164 - 16,973,103 (+)NCBI
Cytogenetic Map8q13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or7g12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8824,850,668 - 24,851,606 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl824,850,668 - 24,851,606 (+)EnsemblGRCr8
mRatBN7.2816,574,372 - 16,575,310 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl816,574,372 - 16,575,310 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx820,559,065 - 20,560,003 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0818,856,902 - 18,857,840 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0816,788,984 - 16,789,922 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0818,845,579 - 18,846,517 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl818,845,579 - 18,846,517 (+)Ensemblrn6Rnor6.0
Rnor_5.0818,913,855 - 18,914,793 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4816,972,165 - 16,973,103 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera817,991,828 - 17,992,766 (+)NCBICelera
RGSC_v3.1816,972,164 - 16,973,103 (+)NCBI
Cytogenetic Map8q13NCBI
OR7G3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38199,126,012 - 9,126,950 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl199,126,012 - 9,126,950 (-)Ensemblhg38GRCh38
GRCh37199,236,688 - 9,237,626 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36199,097,688 - 9,098,626 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34199,097,687 - 9,098,626NCBI
Celera199,132,131 - 9,133,069 (-)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef198,818,259 - 8,819,197 (-)NCBIHuRef
CHM1_1199,236,401 - 9,237,339 (-)NCBICHM1_1
T2T-CHM13v2.0199,252,207 - 9,253,145 (-)NCBIT2T-CHM13v2.0
Or7g12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39918,899,286 - 18,900,224 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl918,899,286 - 18,900,224 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38918,987,990 - 18,988,928 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl918,987,990 - 18,988,928 (+)Ensemblmm10GRCm38
MGSCv37918,792,434 - 18,793,372 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36918,738,392 - 18,739,330 (+)NCBIMGSCv36mm8
Celera916,265,803 - 16,266,741 (+)NCBICelera
Cytogenetic Map9A2NCBI
cM Map97.18NCBI
LOC100993304
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22014,063,968 - 14,066,905 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11913,048,770 - 13,051,707 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0198,682,570 - 8,683,951 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1199,371,174 - 9,372,379 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl199,371,435 - 9,372,373 (-)EnsemblpanPan2panpan1.1
OR7G3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12051,576,597 - 51,577,535 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2051,576,597 - 51,577,535 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2051,441,134 - 51,442,072 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02052,098,889 - 52,099,827 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2052,098,889 - 52,099,827 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12051,306,123 - 51,307,061 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02051,731,611 - 51,732,549 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02051,974,103 - 51,975,041 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:31
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000039181
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8132882639Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat


Expression

RNA-SEQ Expression

mesenchyme
renal system
reproductive system
1 1 1

Sequence


Ensembl Acc Id: ENSRNOT00000039181   ⟹   ENSRNOP00000030252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl824,850,668 - 24,851,606 (+)Ensembl
mRatBN7.2 Ensembl816,574,372 - 16,575,310 (+)Ensembl
Rnor_6.0 Ensembl818,845,579 - 18,846,517 (+)Ensembl
RefSeq Acc Id: NM_001000881   ⟹   NP_001000881
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8824,850,668 - 24,851,606 (+)NCBI
mRatBN7.2816,574,372 - 16,575,310 (+)NCBI
Rnor_6.0818,845,579 - 18,846,517 (+)NCBI
Rnor_5.0818,913,855 - 18,914,793 (+)NCBI
RGSC_v3.4816,972,165 - 16,973,103 (+)RGD
Celera817,991,828 - 17,992,766 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000881 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL78406 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000030252
  ENSRNOP00000030252.2
RefSeq Acc Id: NP_001000881   ⟸   NM_001000881
- UniProtKB: D4A8Q3 (UniProtKB/TrEMBL),   A6JNG0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000030252   ⟸   ENSRNOT00000039181
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A8Q3-F1-model_v2 AlphaFold D4A8Q3 1-312 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333031 AgrOrtholog
BioCyc Gene G2FUF-31567 BioCyc
Ensembl Genes ENSRNOG00000026489 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000039181 ENTREZGENE
  ENSRNOT00000039181.4 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:405180 UniProtKB/TrEMBL
NCBI Gene 405180 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or7g12 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000026489 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6JNG0 ENTREZGENE, UniProtKB/TrEMBL
  D4A8Q3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or7g12  olfactory receptor family 7 subfamily G member 12  Olr1125  olfactory receptor 1125  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1125  olfactory receptor 1125   Olr1125_predicted  olfactory receptor 1125 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1125_predicted  olfactory receptor 1125 (predicted)      Symbol and Name status set to approved 70820 APPROVED