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Strain: WKY, Wistar/Kyoto

Source

Physical Features

Coat color

White (albino)

Behavior

Normal

Other distinguishing features

n/a

Growth/Development

Body weight

8 weeks 10 weeks 13 weeks
Male  118 ± 6 g 192 ± 4 g 242 ± 6 g
Female 151 ± 4 g 178 ± 3 g 174 ± 3 g

Reproduction

Average litter size n/a
Average generation time n/a
Fertility n/a

Phenotype Data

Clinical Measurement
heart rate
systolic blood pressure
diastolic blood pressure
mean arterial blood pressure
body weight
heart weight
blood glucose level
blood urea nitrogen level
serum creatinine level
plasma sodium level
plasma potassium level
heart wet weight
heart weight to body weight ratio
right kidney wet weight
lung wet weight
plasma renin activity level
urine potassium level
urine sodium level
ejection fraction
heart posterior wall thickness
timed urine volume
tibia length
serum potassium level
serum sodium level
heart left ventricle weight to body weight ratio
plasma creatinine level
plasma triglyceride level
plasma aldosterone level
plasma angiotensin II level
plasma total cholesterol level
left ventricular end-systolic blood pressure
left ventricular end-diastolic blood pressure
single kidney wet weight to body weight ratio
single kidney wet weight as percentage of body weight
plasma high density lipoprotein cholesterol level
plasma low density lipoprotein cholesterol level
plasma very low density lipoprotein cholesterol level
heart left ventricle infarction size to total heart left ventricle size ratio
urine protein excretion rate
urine calcium excretion rate
heart left ventricle weight
heart left ventricular end-diastolic diameter
heart left ventricle end-systolic diameter
heart left ventricle fractional shortening
heart ventricle septal wall thickness
kidney glomerulosclerotic lesion measurement
index of glomerular damage
plasma corticosterone level
heart weight to tibia length ratio
kidney fibrotic lesion area to total kidney area ratio
kidney sclerotic glomeruli count to total glomeruli count ratio
ethanol intake volume to total fluid intake volume ratio
liver cholesterol level
liver triglyceride level
ethanol drink intake rate to body weight ratio
maximum rate of positive change in left ventricular blood pressure
blood ethanol clearance rate
decrease in blood ethanol level to body weight ratio per unit time
kidney renin level
kidney glomerulus volume
heart angiotensin I converting enzyme 2 activity level
heart angiotensin I converting enzyme activity level
kidney angiotensin I converting enzyme 2 activity level
kidney angiotensin I converting enzyme activity level
lung angiotensin I converting enzyme 2 activity level
lung angiotensin I converting enzyme activity level
kidney sclerotic glomerular volume to total kidney glomerular volume ratio
heart left ventricle weight to tibia length ratio
E/A wave ratio
artery tunica media width to artery inner diameter ratio

Note: data from males, under standard conditions.


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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.