Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

Physiological Pathway Diagrams

RGD’s Physiological Pathway Diagrams

RGD’s Physiological Pathway Diagrams present systems level pathways, allowing users to view the interactions at the whole animal level or drill down to explore the complex networks of signals and responses.  The Physiological Pathway Diagrams also link to the molecular and cellular pathways giving users a glimpse into how these pathways work together to build the physiological systems.  More pathways will be added soon so check back often.

Software requirements

Insulin Action Pathway

The systemic response to a glucose load begins with stimulation of pancreatic insulin release and proceeds with multiple insulin actions within many different organs and tissues.

Renal Fluid Reabsorption Pathway

One important response to a decrease in blood volume is fluid conservation by the kidney stimulated by vasopressin (an ADH, or anti-diuretic hormone) release.

Vascular Smooth Muscle Contraction Pathway

Control of vascular tone is a critical function that modulates local blood flow and blood pressure.  Many different vasoactive hormones and other factors converge on a common process.

   Also, we want your feedback!  Click here to let us know what you think of the physiological pathway diagrams, to report bugs, or to suggest other systems level pathways for which you would like to see diagrams.


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.