Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Pdk members

Pyruvate dehydrogenase kinase (Pdk) members phosphorylate and inhibit the activity of the pyruvate dehydrogenase complex (PDC). Serine residues in the E1 alpha component of PDC have been identified as phosphorylation sites. The four members of the family are listed with aliases in parentheses, full names and links to gene report pages:

Pdk1 – pyruvate dehydrogenase kinase isoform 1
Pdk2 (Pdhk2) – pyruvate dehydrogenase kinase isoform 2
Pdk3 – pyruvate dehydrogenase kinase isoform 3
Pdk4 – pyruvate dehydrogenase kinase isoform 4


NHLBI Logo

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.