negative regulators

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negative regulators

The negative regulators of Il-1 signaling include the specific natural antagonist and the decoy receptor (type 2) and the broader scope regulator. The three regulators are listed with aliases in parentheses, full names and links to gene report pages:

Il1rn (IL-1RN) – interleukin 1 receptor antagonist
Il1r2 (IL-1RT2, IL-1R2) – interleukin 1 receptor type 2
Sigirr (TIR8) – single Ig and TIR domain containing

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.