Map3k7-Tab(s) complex

Map3k7-Tab(s) complex

Once dissociated from the receptor complex, Irak1-Traf6 interact with a pre-formed Map3k7-Tab1-Tab2-Tab3 complex at the membrane. The four components of this complex are listed with aliases in parentheses, full names and links to gene report pages:

Map3k7 (Tak1) – mitogen activated protein kinase kinase kinase 7
Tab1 (Map3k7ip1) – TGF-beta activated kinase 1/MAP3K7 binding protein 1
Tab2 (Map3k7ip2) – TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 (MAP3K7IP3) – TGF-beta activated kinase 1/MAP3K7 binding protein 3 (human gene)

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

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Map3k7-Tab(s) complex