Immune and Inflammatory Disease Portal – Related Links

Websites and Databases

RGD Interactive Pathway Suite Network Diagrams

Balancing Inflammatory Responses Pathway Suite Network
Network includes:

    Anti-inflammatory HPA Axis, Interleukin-10 and Related Pathways Suite
Suite includes:
Corticotropin-releasing hormone signaling pathway
Melanocortin system pathway
Protein kinase A (PKA) signaling pathway
Cortisol biosynthetic pathway
Cortisol signaling pathway
Cholesterol biosynthetic pathway
Sterol regulatory element-binding protein signaling pathway
Interleukin-10 signaling pathway

  Gene Expression and Regulation Pathway Suite Network
  Network includes:

Transcription and Transcription-Coupled Events Pathway Suite
Suite includes:
RNA polymerase I transcription pathway
RNA polymerase II transcription pathway
RNA polymerase III transcription pathway
Spliceosomal pathway

Epigenetic Regulation/Control – Chromatin Modification/Remodeling
    Pathway Suite Suite includes:
Chromatin remodeling pathway
DNA modification pathway
Histone modification pathway

  Glucose Homeostasis Pathway Suite Network Network includes:

Pathway Suite for the Metabolism of Glucose and Related Molecules
    Pathways Suite includes:
Glycolysis pathway
Pyruvate metabolic pathway
Pentose phosphate pathway
Hexosamine biosynthetic pathway
Glycogen biosynthetic pathway
Gluconeogenesis pathway
Glycogen degradation pathwayRGD Interactive Pathway Suite Diagrams

  Calcium Homeostasis Pathway Suite Suite includes:
Calcium transport pathway
Calcium/calcium-mediated signaling pathway
Calcium signaling pathway via the calcium-sensing receptor
Parathyroid hormone signaling pathway
Calcium/calmodulin dependent kinase 2 signaling pathway

NIH Institutes with information on diseases associated with immunity and inflammation:

National Institute of Allergy and Infectious Diseases (NIAID)
NIAID:  Allergic Diseases
NIAID:  Asthma
NIAID:  Autoimmune Diseases
NIAID:  Immune System
NIAID:  Immune Tolerance
NIAID:  Primary Immune Deficiency Diseases

National Heart, Lung and Blood Institute (NHLBI)
NHLBI:  Asthma
NHLBI:  Hypersensitivity pneumonitis
NHLBI:  Lymphocytopenia

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIAMS:  Pemphigus
NIAMS:  Rheumatoid Arthritis
NIAMS:  Systemic Lupus Erythematosus
NIAMS:  Understanding Autoimmune Diseases
NIAMS:  Understanding Autoinflammatory Diseases

National Human Genome Research Institute (NHGRI)
NHGRI:  Antiphospholipid Syndrome (APS)
NHGRI:  Familial Mediterranean Fever
NHGRI:  Severe Combined Immunodeficiency (SCID)

U. S. National Library of Medicine Genetics Home Reference
Health Conditions A-Z
    Immune system A-Z

Additional Resources (Pages listed for any particular resource are not exhaustive):

National Organization for Rare Disorders
    Rare Disease Information A-Z

European Society for Immunodeficiencies

European Society for Immunodeficiencies Registry (login required to access data)

Immune Disease Institute (Harvard Medical School Affiliate)

Immune Epitope Database and Analysis Resource (La Jolla Institute for Allergy and Immunology)

Kaiser Permanente Autoimmune Disease Registry

The Registry of Hereditary Auto-inflammatory Disorders Mutations (Infevers)

Medline Plus
Medline Plus:  Addison’s Disease
Medline Plus:  Allergy
Medline Plus:  Arthritis
Medline Plus:  Asthma
Medline Plus:  Ataxia Telangiectasia
Medline Plus:  Autoimmune Diseases
Medline Plus:  HIV/AIDS
Medline Plus:  Immune System and Disorders

Online Mendelian Inheritance in Man (OMIM)
    OMIM:  Asthma
OMIM:  Autoimmune Disease
OMIM:  Autoinflammatory Disease
OMIM:  Rheumatoid Arthritis

Centers for Disease Control and Prevention
CDC:  Arthritis
CDC:  Asthma
CDC:  HIV/AIDS

Genes and Disease
Genes and Disease:  Diseases of the Immune System
Genes and Disease:  Severe combined immunodeficiency
Genes and Disease:  Asthma
Genes and Disease:  Ataxia Telangiectasia
Genes and Disease:  Familial Mediterranean fever

World Health Organization (WHO)
WHO:  Asthma
WHO:  Global KnowledgeBase on Transplantation (GKT)
WHO:  HIV/AIDS
WHO:  Infectious diseases

Pro-inflammatory Nuclear Factor Kappa B, Toll-like Receptor, Interleukins and Related Signaling Pathways SuiteSuite includes:
  Nuclear factor kappa B signaling pathway
Toll-like receptor signaling pathway
Interleukin 1 signaling pathway
Interleukin-6 signaling pathway
Tumor necrosis factor signaling pathway

RNA Maturation, Transport and Surveillance (QC) and Protein Translation Pathway Suite Suite includes:
Spliceosomal pathway
mRNA nuclear export pathway
Ribosome biogenesis pathway
Translation pathway

Pathway Suite for the Glucose Homeostasis-related Regulatory and Signaling Pathways Suite includes:
Insulin Secretion Pathway
Insulin Responsive Facilitated Sugar Transporter Mediated Glucose
Transport Pathway
Insulin Signaling Pathway
Glucagon Signaling Pathway

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