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Palmer, Abraham, Ph.D.

Professor, Department of Psychiatry
University of California, San Diego
9500 Gilman Drive #0667
La Jolla, CA  92093-0667


Research Interests:
   – quantitative genetics in outbred populations
– expression QTLs
– behavioral models related to drug abuse, ADHD, fear and anxiety

Since 2005 my laboratory has been developing methods to perform GWAS in outbred rodent populations. Until 2012 this work was done exclusively in mice. More recently I have been attracted to rats because they are capable of performing very sophisticated behavioral tasks that are difficult or impossible in mice. My goal is to replicate our prior successes performing GWAS for behavioral traits in mice with more sophisticated and interesting rat behavioral paradigms. We are leveraging the power of fine mapping populations like the N/NIH stock (from Dr. Leah Solberg Woods) and commercially available outbred stocks (e.g. Sprague Dawley). These populations allow us to identify very small regions that are associated with behavioral and other traits of interest. We can then incorporate eQTL information to parse among possible candidate genes within these regions. Our behavioral work is done in collaboration with well-established rat behavior labs that have the necessary theoretical and technical expertise.



RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.