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Databases and Websites:

RGD Interactive Pathway Suite Network Diagrams

Balancing Blood Pressure Regulatory Mechanisms Pathway Suite Network Network includes:

    Mechanisms Mediating and Pertinent to Decreased Blood Pressure
    Pathway Suite Suite includes:
Kallikrein-kinin cascade pathway
Kinin signaling pathway
Angiotensin II signaling pathway via AT2 receptor

Mechanisms Mediating and Pertinent to Both Increased and Decreased
    Blood Pressure Pathway Suite Suite includes:
Renin-angiotensin cascade pathway
Angiotensin II signaling pathway
Protein kinase C (PKC) signaling pathway
Calcium transport pathway
Calcium/calcium-mediated signaling pathway

  Gene Expression and Regulation Pathway Suite Network Network includes:

Transcription and Transcription-Coupled Events Pathway Suite Suite includes:
RNA polymerase I transcription pathway
RNA polymerase II transcription pathway
RNA polymerase III transcription pathway
Spliceosomal pathway

Epigenetic Regulation/Control – Chromatin Modification/Remodeling
    Pathway Suite Suite includes:
Chromatin remodeling pathway
DNA modification pathway
Histone modification pathway

  Glucose Homeostasis Pathway Suite Network Network includes:

Pathway Suite for the Metabolism of Glucose and Related Molecules
    Pathways Suite includes:
Glycolysis pathway
Pyruvate metabolic pathway
Pentose phosphate pathway
Hexosamine biosynthetic pathway
Glycogen biosynthetic pathway
Gluconeogenesis pathway
Glycogen degradation pathway

RGD Interactive Pathway Suite Diagrams

Energy Homeostasis Suite Suite includes:
Citric acid cycle pathway
Insulin signaling pathway
Leptin system pathway
Melanocortin system pathway
mTOR signaling pathway
Adenosine monophosphate-activated protein kinase (AMPK) signaling

Mechanisms Mediating and Pertinent to Increased Blood Pressure Pathway Suite Suite includes:
Angiotensin II signaling pathway via AT1 receptor
Aldosterone signaling pathway
Aldosterone biosynthetic pathway
Cholesterol biosynthetic pathway
Sterol regulatory element-binding protein signaling pathway
Losartan drug pathway
Statin drug pathway

RNA Maturation, Transport and Surveillance (QC) and Protein Translation Pathway Suite Suite includes:
Spliceosomal pathway
mRNA nuclear export pathway
Ribosome biogenesis pathway
Translation pathway

Pathway Suite for the Glucose Homeostasis-related Regulatory and Signaling Pathways Suite includes:
Insulin Secretion Pathway
Insulin Responsive Facilitated Sugar Transporter Mediated Glucose Transport Pathway
Insulin Signaling Pathway
Glucagon Signaling Pathway

Beta Adrenergic Receptor Pathway Suite Suite includes:
    Epinephrine biosynthetic pathway
Epinephrine signaling via beta adrenergic receptors
Adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway

Calcium Homeostasis Pathway Suite Suite includes:
Calcium transport pathway
Calcium/calcium-mediated signaling pathway
Calcium signaling pathway via the calcium-sensing receptor
Parathyroid hormone signaling pathway
Calcium/calmodulin dependent kinase 2 signaling pathway


National Heart, Lung, and Blood Institute (NHLBI)

U.S. National Library of Medicine Genetics Home Reference
       Health Conditions A-Z
      Heart & Circulation A-Z 

National Organization for Rare Disorders
Rare Disease Information A-Z

Physgen – cardiovascular phenotype database


American Heart Association


Genetic Association Database Please note that the Genetic Association Database has been retired. This link will take you to a page with options to download the data from August 2014.

Human Gene Mutation Database

NCBI – Genes and Disease: The Heart and Blood Vessels

Online Mendelian Inheritance in Man (OMIM)

Med Assisting’s Learning Resources on the Cardiovascular System and its Diseases

Links to Cardiovascular Disease-Related Videos

Congestive Heart Failure
This is a 3D medical animation that describes and shows the causes of congestive heart failure.

Acute Coronary Syndrome
Symptoms of chest pain are due to insufficient blood supply to heart muscles caused by coronary heart disease. Watch this 3D animation to learn more.

Heart Attack
This is a 3D coronary artery disease video that describes what happens during a heart attack.

Angina Animation
Watch this helpful animation to learn more about angina, a symptom of coronary heart disease.


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