Strain Report - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Strain Registration

Strain: BN.SHR-(Il6-Cd36)/Cub

Symbol: BN.SHR-(Il6-Cd36)/Cub
Strain: BN.SHR-(Il6-Cd36)
Substrain: Cub
RGD ID: 728142
Citation ID: RRID:RGD_728142
Ontology ID: RS:0000129
Also Known As: BN.SHR4; BN.SHR-(Il6-Cd36)/Cub; BN-SHR4
Type: congenic
Available Source: Not Available
Origination: Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic
Description: This congenic strain has a segment of chr 4 which was of SHR origin. The length of the differential segment is 10 cM and has a defective cd36 allele of SHR.
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.245,214,602 - 17,410,084RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.043,043,231 - 14,191,498RGD_MAPPER_PIPELINERnor6.0
Rnor_5.043,095,536 - 14,166,434RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.44456,799 - 13,554,416RGD_MAPPER_PIPELINERGSC3.4





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Pharmacogenetic interaction between dexamethasone and Cd36-deficient segment of spontaneously hypertensive rat chromosome 4 affects triacylglycerol and cholesterol distribution into lipoprotein fractions. Krupkova M, etal., Lipids Health Dis. 2010 Apr 16;9:38.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines
3. Metabolic characterization of insulin resistance syndrome feature loci in three brown Norway-derived congenic strains. Seda O, etal., Folia Biol (Praha) 2002;48(3):81-8.
4. Rosiglitazone fails to improve hypertriglyceridemia and glucose tolerance in CD36-deficient BN.SHR4 congenic rat strain. Seda O, etal., Physiol Genomics 2003 Jan 15;12(2):73-8.

Region

Position Markers

Flank 1 / 1 (Il6)
Rat AssemblyChrPosition (strand)Source
GRCr845,889,999 - 5,894,575 (-)NCBI
mRatBN7.245,214,602 - 5,219,178 (-)NCBI
mRatBN7.2 Ensembl45,213,394 - 5,219,178 (-)Ensembl
UTH_Rnor_SHR_Utx410,211,864 - 10,216,458 (-)NCBI
UTH_Rnor_SHRSP_BbbUtx_1.046,026,101 - 6,030,695 (-)NCBI
UTH_Rnor_WKY_Bbb_1.044,372,235 - 4,376,829 (-)NCBI
Rnor_6.043,043,231 - 3,047,807 (+)NCBI
Rnor_6.0 Ensembl43,043,231 - 3,047,807 (+)Ensembl
Rnor_5.043,095,536 - 3,100,112 (+)NCBI
RGSC_v3.44456,799 - 461,376 (-)NCBI
RGSC_v3.14456,798 - 461,376 (-)NCBI
Celera45,093,593 - 5,098,169 (+)NCBI
Cytogenetic Map4q11NCBI

Flank 2 / 1 (Cd36)
Rat AssemblyChrPosition (strand)Source
GRCr8418,209,088 - 18,302,142 (+)NCBI
mRatBN7.2417,317,343 - 17,410,084 (+)NCBI
mRatBN7.2 Ensembl417,354,466 - 17,513,903 (+)Ensembl
UTH_Rnor_SHR_Utx422,477,636 - 22,533,306 (+)NCBI
UTH_Rnor_SHRSP_BbbUtx_1.0418,290,445 - 18,348,857 (+)NCBI
UTH_Rnor_WKY_Bbb_1.0416,675,588 - 16,731,247 (+)NCBI
Rnor_6.0414,150,309 - 14,191,498 (+)NCBI
Rnor_6.0 Ensembl414,001,761 - 14,249,749 (+)Ensembl
Rnor_5.0414,125,297 - 14,166,434 (+)NCBI
RGSC_v3.4413,534,582 - 13,554,416 (+)NCBI
Celera412,880,238 - 12,941,086 (+)NCBI
Cytogenetic Map4q11NCBI

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Shows a significant increase in triglyceride level when fed a high-sucrose diet for 1 week. 632347
strain_life_disease This region is important for dyslipidemia and insulin resistance. 632347