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General

Strain: BBDP.WF-(D8Rat59-D8Sunn1467)/Sunn

Symbol:

BBDP.WF-(D8Rat59-D8Sunn1467)/Sunn

Strain:

BBDP.WF-(D8Rat59-D8Sunn1467)

Substrain:

Sunn

RGD ID:

1599674

Citation ID:

RRID:RGD_1599674

Ontology ID:

RS:0001176

Also Known As:

8e; BBDP.WF-(D8Rat59-D8Sunn1467)/Sunn

Type:

congenic

Available Source:

Not Available

Origination:

Department of Medicine and Immunology, University of Toronto, Toronto, Ontario, Canada

Description:

WF RT7.2 allele was introgressed onto the genetic background of BBDP rats and these were crossed with BBDP

Last Known Status:

Unknown

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	123,815,688 - 123,815,899	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	8	133,272,922 - 133,273,132	RGD_MAPPER_PIPELINE	Rnor_6.0
Rnor_5.0	8	115,112,735 - 132,425,312	RGD_MAPPER_PIPELINE	Rnor_5.0
RGSC_v3.4	8	112,242,639 - 128,970,675	RGD_MAPPER_PIPELINE	RGSC_v3.4

Annotation Click to see Annotation Detail View

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

decreased susceptibility to autoimmune diabetes (IAGP)

Phenotype Values via PhenoMiner Click to see Annotation Detail View

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Clinical Measurement

percentage of study population developing type 1 diabetes mellitus during a period of time

References

References - curated

#	Reference Title	Reference Citation
1.	RGD Strain RSO annotation pipeline	RGD Automated Pipelines
2.	A novel susceptibility locus on rat chromosome 8 affects spontaneous but not experimentally induced type 1 diabetes.	Wallis RH, etal., Diabetes. 2007 Jun;56(6):1731-6. Epub 2007 Mar 27

Region

Position Markers

Flank 1 / 1 (D8Rat59)

Rat Assembly	Chr	Position (strand)	Source
Rnor_5.0	8	115,112,735 - 115,113,003	NCBI
RGSC_v3.4	8	112,242,639 - 112,242,906	RGD
RGSC_v3.1	8	112,262,094 - 112,262,361	RGD
RH 3.4 Map	8	1127.5	UniSTS
RH 3.4 Map	8	1127.5	RGD
RH 2.0 Map	8	872.8	RGD
SHRSP x BN Map	8	71.0	RGD
FHH x ACI Map	8	79.01	RGD

Flank 2 / 1 (D8Sunn1467)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	123,815,688 - 123,815,899 (+)	MAPPER
Rnor_6.0	8	133,272,922 - 133,273,132	NCBI
Rnor_5.0	8	132,425,102 - 132,425,312	UniSTS
RGSC_v3.4	8	128,970,465 - 128,970,675	UniSTS
Celera	8	122,910,769 - 122,910,987	UniSTS
Cytogenetic Map	8		RGD

Strain QTL Data

Symbol	Name	Trait
Iddm24	Insulin dependent diabetes mellitus QTL 24	blood glucose amount (VT:0000188)

Additional Information

RGD Curation Notes

Note Type	Note	Reference
strain_characteristics	incorporates the region from D8Rat121 to the telomere harboring QTL Iddm24	1624306
strain_other	this strain shows no significant difference in age of type 1 diabetes onset between BBDP.WF-(D8Rat16-D8Sunn1467)/Sunn	1624306

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: BBDP.WF-(D8Rat59-D8Sunn1467)/Sunn

Mammalian Phenotype

Related Phenotype Data for Term "BBDP.WF-(D8Rat59-D8Sunn1467)/Sunn" (RS:0001176)