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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:scatter factor/hepatocyte growth factor signaling pathway
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Accession:PW:0000578 term browser browse the term
Definition:Scatter factor/hepatocyte growth factor signaling impacts on various biological processes such as proliferation and survival, morphogenesis and motility. SF/HGF and its receptor c-Met have also been implicated in tumor growth and angiogenesis.
Synonyms:related_synonym: SF/HGF signaling pathway;   Signaling by MET;   hepatocyte growth factor receptor signaling pathway
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scatter factor/hepatocyte growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbl Cbl proto-oncogene ISO RGD PMID:18175071 RGD:2299174 NCBI chr 8:53,384,656...53,468,067
Ensembl chr 8:53,384,656...53,468,067 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein ISO RGD PMID:14685170 RGD:1642762 NCBI chr11:97,033,033...97,067,457
Ensembl chr11:97,024,782...97,067,457 		JBrowse link
G Gab1 GRB2-associated binding protein 1 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr19:44,035,693...44,143,617
Ensembl chr19:44,035,063...44,143,617 		JBrowse link
G Grb2 growth factor receptor bound protein 2 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138 		JBrowse link
G Hgf hepatocyte growth factor ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase ISO
IMP 		RGD PMID:14685170 PMID:18175071 PMID:17065554 RGD:1642762, RGD:2299174, RGD:2317513 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347 		JBrowse link
G Plcg1 phospholipase C, gamma 1 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:169,804,846...169,836,050 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr12:41,026,079...41,085,577
Ensembl chr12:41,043,785...41,085,577 		JBrowse link
G Shc1 SHC adaptor protein 1 ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:14685170 PMID:18175071 RGD:1642762, RGD:2299174 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462 		JBrowse link
altered scatter factor/hepatocyte growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Met MET proto-oncogene, receptor tyrosine kinase ISO RGD PMID:20519133 PMID:20951313 PMID:21277552 PMID:19506583 RGD:5133241, RGD:5133242, RGD:5133243, RGD:5490965 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    signaling pathway 2635
      growth factor signaling pathway 523
        scatter factor/hepatocyte growth factor signaling pathway 11
          altered scatter factor/hepatocyte growth factor signaling pathway 1
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