Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Pitpnb (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PITPNB mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | increases expression | ISO | Pitpnb (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of PITPNB mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Estradiol results in increased expression of PITPNB mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Pitpnb (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PITPNB mRNA | CTD | PMID:21570461 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | ISO | Pitpnb (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:18550172 | 4,4'-sulfonyldiphenol | increases expression | ISO | PITPNB (Homo sapiens) | 6480464 | bisphenol S results in increased expression of PITPNB protein | CTD | PMID:34186270 | aconitine | decreases expression | EXP | | 6480464 | Aconitine results in decreased expression of PITPNB protein | CTD | PMID:33236894 | acrolein | multiple interactions | ISO | PITPNB (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PITPNB mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PITPNB mRNA | CTD | PMID:32699268 | aflatoxin B1 | decreases methylation | ISO | PITPNB (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of PITPNB gene | CTD | PMID:27153756 | aflatoxin B1 | increases methylation | ISO | PITPNB (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of PITPNB intron | CTD | PMID:30157460 | all-trans-retinoic acid | decreases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of PITPNB mRNA | CTD | PMID:15498508 and PMID:33167477 | alpha-pinene | multiple interactions | ISO | PITPNB (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PITPNB mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PITPNB mRNA | CTD | PMID:32699268 | aminoglutethimide | increases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Aminoglutethimide results in increased expression of PITPNB protein | CTD | PMID:26102013 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of PITPNB mRNA | CTD | PMID:16483693 | aristolochic acid A | decreases expression | ISO | PITPNB (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of PITPNB mRNA | CTD | PMID:33212167 | atrazine | decreases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Atrazine results in decreased expression of PITPNB mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of PITPNB protein | CTD | PMID:33278487 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | PITPNB (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 and PMID:20382639 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PITPNB mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | PITPNB (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of PITPNB mRNA | CTD | PMID:29275510 | bisphenol F | increases expression | ISO | PITPNB (Homo sapiens) | 6480464 | bisphenol F results in increased expression of PITPNB protein | CTD | PMID:34186270 | cadmium dichloride | increases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of PITPNB mRNA | CTD | PMID:26472689 | carbon nanotube | increases expression | ISO | Pitpnb (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of PITPNB mRNA | CTD | PMID:25554681 | chlorpyrifos | decreases expression | ISO | Pitpnb (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of PITPNB mRNA | CTD | PMID:37019170 | cisplatin | multiple interactions | ISO | PITPNB (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of PITPNB mRNA | CTD | PMID:27392435 | clozapine | increases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Clozapine results in increased expression of PITPNB protein | CTD | PMID:34122009 | copper(II) sulfate | increases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of PITPNB mRNA | CTD | PMID:19549813 | crocidolite asbestos | increases expression | ISO | Pitpnb (Mus musculus) | 6480464 | Asbestos and Crocidolite results in increased expression of PITPNB mRNA | CTD | PMID:19446018 | cyclosporin A | increases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PITPNB mRNA | CTD | PMID:20106945 | doxorubicin | decreases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PITPNB mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | PITPNB (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of PITPNB protein | CTD | PMID:23301498 | ethanol | multiple interactions | ISO | Pitpnb (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of PITPNB mRNA | CTD | PMID:30319688 | folic acid | decreases expression | ISO | Pitpnb (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PITPNB mRNA | CTD | PMID:25629700 | FR900359 | decreases phosphorylation | ISO | PITPNB (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of PITPNB protein | CTD | PMID:37730182 | gallic acid | decreases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Gallic Acid results in decreased expression of PITPNB mRNA | CTD | PMID:34408198 | glyphosate | increases methylation | EXP | | 6480464 | Glyphosate results in increased methylation of PITPNB gene | CTD | PMID:31011160 | hydrogen peroxide | affects expression | ISO | PITPNB (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of PITPNB mRNA | CTD | PMID:20044591 | hydrogen peroxide | multiple interactions | ISO | PITPNB (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PITPNB protein | CTD | PMID:18951874 | hydroquinone O-beta-D-glucopyranoside | increases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Arbutin results in increased expression of PITPNB mRNA | CTD | PMID:17103032 | ivermectin | decreases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of PITPNB protein | CTD | PMID:32959892 | kojic acid | increases expression | ISO | PITPNB (Homo sapiens) | 6480464 | kojic acid results in increased expression of PITPNB mRNA | CTD | PMID:16595896 | lithium chloride | increases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Lithium Chloride results in increased expression of PITPNB mRNA | CTD | PMID:15711924 | ochratoxin A | decreases expression | ISO | PITPNB (Homo sapiens) | 6480464 | ochratoxin A results in decreased expression of PITPNB protein | CTD | PMID:26861962 | ozone | multiple interactions | ISO | PITPNB (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PITPNB mRNA more ... | CTD | PMID:32699268 and PMID:35430440 | ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of PITPNB mRNA | CTD | PMID:35737395 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Pitpnb (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PITPNB mRNA | CTD | PMID:36331819 | perfluorooctanoic acid | increases expression | ISO | Pitpnb (Mus musculus) | 6480464 | perfluorooctanoic acid results in increased expression of PITPNB mRNA | CTD | PMID:17681415 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of PITPNB mRNA | CTD | PMID:19162173 | progesterone | affects expression | ISO | Pitpnb (Mus musculus) | 6480464 | Progesterone affects the expression of PITPNB mRNA | CTD | PMID:17251523 | resveratrol | multiple interactions | ISO | PITPNB (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of PITPNB mRNA | CTD | PMID:23557933 | sodium arsenite | increases expression | ISO | PITPNB (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PITPNB mRNA | CTD | PMID:17879257 | sodium dodecyl sulfate | decreases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Sodium Dodecyl Sulfate results in decreased expression of PITPNB protein | CTD | PMID:21469165 | sunitinib | increases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Sunitinib results in increased expression of PITPNB mRNA | CTD | PMID:31533062 | tamibarotene | affects expression | ISO | PITPNB (Homo sapiens) | 6480464 | tamibarotene affects the expression of PITPNB mRNA | CTD | PMID:15498508 | thapsigargin | increases expression | EXP | | 6480464 | Thapsigargin results in increased expression of PITPNB protein | CTD | PMID:35544339 | theophylline | multiple interactions | ISO | PITPNB (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of PITPNB protein | CTD | PMID:18951874 | titanium dioxide | decreases expression | ISO | Pitpnb (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of PITPNB mRNA | CTD | PMID:29264374 | valproic acid | decreases expression | ISO | Pitpnb (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of PITPNB mRNA | CTD | PMID:21427059 | valproic acid | decreases methylation | ISO | PITPNB (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of PITPNB gene | CTD | PMID:29154799 | vincristine | decreases expression | ISO | PITPNB (Homo sapiens) | 6480464 | Vincristine results in decreased expression of PITPNB mRNA | CTD | PMID:23649840 | |