Adamtsl5 (ADAMTS-like 5) - Rat Genome Database

Name: Adamtsl5
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Adamtsl5 (ADAMTS-like 5) Rattus norvegicus

Analyze

Symbol:

Adamtsl5

Name:

ADAMTS-like 5

RGD ID:

1305607

Description:

Predicted to enable heparin binding activity and microfibril binding activity. Predicted to be involved in extracellular matrix organization. Predicted to be located in extracellular region and microfibril. Orthologous to human ADAMTSL5 (ADAMTS like 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ADAMTS-like protein 5; LOC314626; thrombospondin, type I domain containing 6; Thsd6

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ADAMTSL5 (ADAMTS like 5)	HGNC	Ensembl, HomoloGene, NCBI, OrthoDB, Panther
Mus musculus (house mouse):	Adamtsl5 (ADAMTS-like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Adamtsl5 (ADAMTS like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ADAMTSL5 (ADAMTS like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ADAMTSL5 (ADAMTS like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Adamtsl5 (ADAMTS like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ADAMTSL5 (ADAMTS like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ADAMTSL5 (ADAMTS like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Adamtsl5 (ADAMTS like 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ADAMTSL5 (ADAMTS like 5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Adamtsl5 (ADAMTS-like 5)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	adamtsl5 (ADAMTS like 5)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	adamtsl5	Alliance	DIOPT (Ensembl Compara\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	XB995277 [provisional:adamtsl5]	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	10,013,306 - 10,021,924 (+)	NCBI		GRCr8
mRatBN7.2	7	9,362,623 - 9,371,248 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	9,363,237 - 9,370,285 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	12,240,171 - 12,248,160 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	14,115,513 - 14,123,502 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	11,982,872 - 11,990,862 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	12,228,706 - 12,237,382 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	12,229,379 - 12,234,576 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	12,398,544 - 12,407,177 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	10,874,586 - 10,879,783 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	10,874,856 - 10,881,378 (+)	NCBI
Celera	7	7,540,043 - 7,545,236 (+)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cerebral creatine deficiency syndrome (ISO)

cyclic hematopoiesis (ISO)

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

progressive myoclonus epilepsy 9 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (EXP)

amitrole (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cantharidin (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

clotrimazole (EXP)

diuron (EXP)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

folic acid (ISO)

gentamycin (EXP)

hydrogen cyanide (ISO)

L-methionine (ISO)

methamphetamine (ISO)

methimazole (EXP)

ozone (ISO)

paraquat (EXP)

perfluorohexanesulfonic acid (ISO)

perfluorooctanoic acid (ISO)

potassium cyanide (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

titanium dioxide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

extracellular matrix organization (IEA)

proteolysis (IEA)

Cellular Component

extracellular matrix (ISO)

extracellular region (ISO)

microfibril (ISO)

Molecular Function

heparin binding (ISO)

metalloendopeptidase activity (IEA)

microfibril binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:23010571

Genomics

Comparative Map Data

Adamtsl5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	10,013,306 - 10,021,924 (+)	NCBI		GRCr8
mRatBN7.2	7	9,362,623 - 9,371,248 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	9,363,237 - 9,370,285 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	12,240,171 - 12,248,160 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	14,115,513 - 14,123,502 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	11,982,872 - 11,990,862 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	12,228,706 - 12,237,382 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	12,229,379 - 12,234,576 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	12,398,544 - 12,407,177 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	10,874,586 - 10,879,783 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	10,874,856 - 10,881,378 (+)	NCBI
Celera	7	7,540,043 - 7,545,236 (+)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

ADAMTSL5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	1,505,022 - 1,513,019 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	1,505,022 - 1,513,604 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	1,505,021 - 1,513,018 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	1,456,023 - 1,464,019 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	1,439,031 - 1,447,215 (-)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	1,279,125 - 1,287,301 (-)	NCBI		HuRef
CHM1_1	19	1,505,011 - 1,513,186 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	1,475,471 - 1,483,468 (-)	NCBI		T2T-CHM13v2.0

Adamtsl5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	80,175,655 - 80,184,246 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	80,174,944 - 80,184,246 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	80,339,793 - 80,349,030 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	80,339,110 - 80,348,412 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	79,803,461 - 79,811,191 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	79,745,868 - 79,751,541 (-)	NCBI		MGSCv36	mm8
Celera	10	81,355,595 - 81,363,325 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Adamtsl5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955764	5,177 - 12,653 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955764	4,813 - 12,653 (+)	NCBI	ChiLan1.0	ChiLan1.0

ADAMTSL5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	5,872,800 - 5,881,392 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	5,103,655 - 5,111,344 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1	19	1,478,985 - 1,486,135 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

ADAMTSL5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	57,351,242 - 57,357,934 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	57,351,575 - 57,357,520 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	57,143,728 - 57,150,940 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	58,082,986 - 58,089,064 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	20	57,140,473 - 57,146,436 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	57,618,525 - 57,624,710 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	57,820,452 - 57,827,673 (+)	NCBI		UU_Cfam_GSD_1.0

Adamtsl5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	217,017,133 - 217,023,905 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	810,234 - 817,656 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	810,880 - 817,636 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADAMTSL5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	76,966,766 - 76,975,820 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	76,966,155 - 76,975,555 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	78,106,381 - 78,114,033 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ADAMTSL5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	1,278,045 - 1,287,257 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	1,279,036 - 1,284,946 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666081	7,565,647 - 7,574,933 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Adamtsl5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	7,192,191 - 7,199,035 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	7,192,160 - 7,201,832 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Adamtsl5
22 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	33
Count of miRNA genes:	29
Interacting mature miRNAs:	31
Transcripts:	ENSRNOT00000060811
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2298550	Neuinf6	Neuroinflammation QTL 6	3.3		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	7	1	27829089	Rat
7411566	Bw136	Body weight QTL 136	10.4	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	7	1	31962314	Rat
9590142	Scort5	Serum corticosterone level QTL 5	24.4	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	7	1	31962314	Rat
724560	Plsm3	Polydactyly-luxate syndrome (PLS) morphotypes QTL 3		0.0003	tibia length (VT:0004357)	tibia length (CMO:0000450)	7	1	34000259	Rat
2317047	Wbc4	White blood cell count QTL 4		0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	7	1	35342956	Rat
61410	Bw19	Body weight QTL 19	6.2	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	7	1	44782185	Rat
631503	Bp102	Blood pressure QTL 102	1.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	1	44822433	Rat
1300176	Hrtrt10	Heart rate QTL 10	3.19		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	7	664270	26029351	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
10755438	Coatc9	Coat color QTL 9		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	3529280	48529280	Rat
9590102	Sffal5	Serum free fatty acids level QTL 5	8.62	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	7	5329019	50329019	Rat
10755440	Coatc10	Coat color QTL 10		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	7496499	52496499	Rat
10059592	Kidm45	Kidney mass QTL 45	3.95	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	7	7573985	52573985	Rat

Markers in Region

BE112763

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	9,368,204 - 9,368,361 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	12,234,339 - 12,234,495	NCBI	Rnor6.0
Rnor_5.0	7	12,404,134 - 12,404,290	UniSTS	Rnor5.0
RGSC_v3.4	7	10,879,546 - 10,879,702	UniSTS	RGSC3.4
Celera	7	7,544,999 - 7,545,155	UniSTS
RH 3.4 Map	7	40.3	UniSTS
Cytogenetic Map	7	q11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		23			1			3			15	1
Low	3	20	53	37	18	37	8	8	37	35	22	10	8
Below cutoff			4	4		4			35		4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108071	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001400960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001400961	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001400962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001400963	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001400965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240917	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240918	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240919	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240920	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078990	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078992	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078993	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078994	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078998	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039078999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039079000	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039079002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063263416	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005486599	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005486600	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC120291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ224249	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000060811 ⟹ ENSRNOP00000057537

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	9,363,245 - 9,368,442 (+)	Ensembl
Rnor_6.0 Ensembl	7	12,229,379 - 12,234,576 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000101922 ⟹ ENSRNOP00000092372

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	9,363,237 - 9,370,285 (+)	Ensembl

RefSeq Acc Id:

NM_001108071 ⟹ NP_001101541

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,955 - 10,019,118 (+)	NCBI
mRatBN7.2	7	9,363,279 - 9,368,442 (+)	NCBI
Rnor_6.0	7	12,229,379 - 12,234,576 (+)	NCBI
Rnor_5.0	7	12,398,544 - 12,407,177 (+)	NCBI
RGSC_v3.4	7	10,874,586 - 10,879,783 (+)	RGD
Celera	7	7,540,043 - 7,545,236 (+)	RGD

Sequence:

show sequence

CAGTCCCGCACTTTGGGGCCCCGCCGCTTCCGCCAGTCCCTGGGGCGACCCAGGGAAGCTTGGA
CGCATTGCCTTGGGCTCTGAGCAACTGACCCTCTGGGCACCGCAGCCCGCACTCCTGGCTGATG
AGACCATGACGCACATGTTGGCAGGAGGCCAGAGACAAGAGGACCCAGAGAGGTTTGGCTACCA
TCGAAGACCACACAGTCAGCCAGGGCTGAGATGGCAGTTCACTCCGATTCTGCTGATCACTGCC
TCTTGGGAACCCAGTGCTCCCTCAGACCCCGCCTCTTCCCGCCTCTTCTGTTCTTGCTGTGGAT
TCTCCTGAGCTGTGATTTGAGGGGTGCTGCTCAGGGTCCGGGAGAGTGGACGCTCTGGGGGTCT
TGGAGCCGGTGTTCCAGCTCGTGTGGTCGGGGCGTCTCAGTGCGCAGACGCCACTGCGTCCGAC
TTCCTGAGGAGGAACTTTGCTGGGGGGACAGTCATGAATACCGGGTGTGCCAGCTGCCGGACTG
CCCCCCAGGGGCCATACCATTCCGAGACCTGCAGTGTTCTCTCTACAATGGCCACCCCGTCCTG
GGCACCCAGAAAACCTATCAATGGGTGCCCTTCCACGGGGCGCCCAATCTGTGTGACCTCAACT
GCCTGGCTGAAGGCCACGCCTTCTACCACAGCTTTGGCCGCGTGCTGGATGGCACCCCCTGCAC
CCCGGGGACCCAGGGTCTCTGCGTGGCAGGCCGCTGTCTGAGCGCAGGCTGTGACGGACTACTG
GGCTCCGGCACCCTCGAGGACCGCTGCGGCCTCTGTGGTGGTGCTAACGACTCTTGCCTGTTCG
TGCAGCGCGTGTTCCGCGACGCCGGTGACTGCCCCATCCCGCCTCACGGCCTGCACTTGAGGAG
CATGGTGGACAGGGGTCCCTTTAACGAGTTTGGCTCCTGGGAGCCAAGACTCTTGCTGATTGGA
CAGGTTAAGGCCCGGCTCCTCGAGGCCTTCCCCTGATTGGCCTCTGACAGAGCGTCCCACCCTC
CCTCGAATAGATGCGCTTTTAACCCCT

hide sequence

RefSeq Acc Id:

NM_001400960 ⟹ NP_001387889

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,955 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,363,279 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

NM_001400961 ⟹ NP_001387890

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,955 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,363,279 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

NM_001400962 ⟹ NP_001387891

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,955 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,363,279 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

NM_001400963 ⟹ NP_001387892

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,955 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,363,279 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

NM_001400965 ⟹ NP_001387894

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,955 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,363,279 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_039078986 ⟹ XP_038934914

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,313 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,362,628 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_039078987 ⟹ XP_038934915

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,318 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,362,632 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_039078988 ⟹ XP_038934916

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,872 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,363,197 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_039078989 ⟹ XP_038934917

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,014,479 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,363,803 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_039078990 ⟹ XP_038934918

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,014,027 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,363,348 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_039078991 ⟹ XP_038934919

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,872 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,363,197 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_039078992 ⟹ XP_038934920

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,320 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,362,632 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_039078993 ⟹ XP_038934921

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,307 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,362,623 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_039078994 ⟹ XP_038934922

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,322 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,362,637 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_039078996 ⟹ XP_038934924

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,872 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,363,045 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_039078998 ⟹ XP_038934926

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,314 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,362,628 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_039078999 ⟹ XP_038934927

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,872 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,363,197 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_039079000 ⟹ XP_038934928

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,991 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,363,314 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_039079002 ⟹ XP_038934930

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,016,139 - 10,021,924 (+)	NCBI
mRatBN7.2	7	9,365,461 - 9,371,248 (+)	NCBI

RefSeq Acc Id:

XM_063263416 ⟹ XP_063119486

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,320 - 10,021,924 (+)	NCBI

RefSeq Acc Id:

XR_005486599

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,307 - 10,020,054 (+)	NCBI
mRatBN7.2	7	9,362,623 - 9,369,416 (+)	NCBI

RefSeq Acc Id:

XR_005486600

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	10,013,306 - 10,020,267 (+)	NCBI
mRatBN7.2	7	9,362,623 - 9,369,591 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101541	(Get FASTA)	NCBI Sequence Viewer
	NP_001387889	(Get FASTA)	NCBI Sequence Viewer
	NP_001387890	(Get FASTA)	NCBI Sequence Viewer
	NP_001387891	(Get FASTA)	NCBI Sequence Viewer
	NP_001387892	(Get FASTA)	NCBI Sequence Viewer
	NP_001387894	(Get FASTA)	NCBI Sequence Viewer
	XP_038934914	(Get FASTA)	NCBI Sequence Viewer
	XP_038934915	(Get FASTA)	NCBI Sequence Viewer
	XP_038934916	(Get FASTA)	NCBI Sequence Viewer
	XP_038934917	(Get FASTA)	NCBI Sequence Viewer
	XP_038934918	(Get FASTA)	NCBI Sequence Viewer
	XP_038934919	(Get FASTA)	NCBI Sequence Viewer
	XP_038934920	(Get FASTA)	NCBI Sequence Viewer
	XP_038934921	(Get FASTA)	NCBI Sequence Viewer
	XP_038934922	(Get FASTA)	NCBI Sequence Viewer
	XP_038934924	(Get FASTA)	NCBI Sequence Viewer
	XP_038934926	(Get FASTA)	NCBI Sequence Viewer
	XP_038934927	(Get FASTA)	NCBI Sequence Viewer
	XP_038934928	(Get FASTA)	NCBI Sequence Viewer
	XP_038934930	(Get FASTA)	NCBI Sequence Viewer
	XP_063119486	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL89289	(Get FASTA)	NCBI Sequence Viewer
	EDL89290	(Get FASTA)	NCBI Sequence Viewer
	EDL89291	(Get FASTA)	NCBI Sequence Viewer
	EDL89292	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000057537
	ENSRNOP00000057537.3
	ENSRNOP00000092372
	ENSRNOP00000092372.1

RefSeq Acc Id:	NP_001101541 ⟸ NM_001108071
- Peptide Label:	isoform 6 precursor
- UniProtKB:	F1M9K2 (UniProtKB/TrEMBL), A6K8M1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAVHSDSADHCLLGTQCSLRPRLFPPLLFLLWILLSCDLRGAAQGPGEWTLWGSWSRCSSSCGR GVSVRRRHCVRLPEEELCWGDSHEYRVCQLPDCPPGAIPFRDLQCSLYNGHPVLGTQKTYQWVP FHGAPNLCDLNCLAEGHAFYHSFGRVLDGTPCTPGTQGLCVAGRCLSAGCDGLLGSGTLEDRCG LCGGANDSCLFVQRVFRDAGDCPIPPHGLHLRSMVDRGPFNEFGSWEPRLLLIGQVKARLLEAF P hide sequence

RefSeq Acc Id:

ENSRNOP00000057537 ⟸ ENSRNOT00000060811

RefSeq Acc Id:	XP_038934921 ⟸ XM_039078993
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038934914 ⟸ XM_039078986
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038934926 ⟸ XM_039078998
- Peptide Label:	isoform X9

RefSeq Acc Id:	XP_038934920 ⟸ XM_039078992
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6GJQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934915 ⟸ XM_039078987
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038934922 ⟸ XM_039078994
- Peptide Label:	isoform X7
- UniProtKB:	A0A8I6GJQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934924 ⟸ XM_039078996
- Peptide Label:	isoform X8
- UniProtKB:	A0A8I6GJQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934916 ⟸ XM_039078988
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6GJQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934919 ⟸ XM_039078991
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6GJQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934927 ⟸ XM_039078999
- Peptide Label:	isoform X10
- UniProtKB:	A0A8I6GJQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934928 ⟸ XM_039079000
- Peptide Label:	isoform X10
- UniProtKB:	A0A8I6GJQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934918 ⟸ XM_039078990
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6GJQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934917 ⟸ XM_039078989
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6GJQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038934930 ⟸ XM_039079002
- Peptide Label:	isoform X12

RefSeq Acc Id:

ENSRNOP00000092372 ⟸ ENSRNOT00000101922

RefSeq Acc Id:	NP_001387894 ⟸ NM_001400965
- Peptide Label:	isoform 2 precursor
- UniProtKB:	A6K8M0 (UniProtKB/TrEMBL), A0A8I6GJQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001387889 ⟸ NM_001400960
- Peptide Label:	isoform 1 precursor
- UniProtKB:	A0A8I6GJQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001387890 ⟸ NM_001400961
- Peptide Label:	isoform 2 precursor
- UniProtKB:	A6K8M0 (UniProtKB/TrEMBL), A0A8I6GJQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001387892 ⟸ NM_001400963
- Peptide Label:	isoform 2 precursor
- UniProtKB:	A6K8M0 (UniProtKB/TrEMBL), A0A8I6GJQ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001387891 ⟸ NM_001400962
- Peptide Label:	isoform 3 precursor

RefSeq Acc Id:	XP_063119486 ⟸ XM_063263416
- Peptide Label:	isoform X11

Protein Domains

ADAMTS/ADAMTS-like cysteine-rich NTR

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M9K2-F1-model_v2	AlphaFold	F1M9K2	1-257	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695021

Promoter ID:

EPDNEW_R5546

Type:

initiation region

Name:

Adamtsl5_1

Description:

ADAMTS-like 5

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	12,229,413 - 12,229,473	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305607	AgrOrtholog
BioCyc Gene	G2FUF-34938	BioCyc
Ensembl Genes	ENSRNOG00000033787	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000060811	ENTREZGENE
	ENSRNOT00000060811.5	UniProtKB/TrEMBL
	ENSRNOT00000101922	ENTREZGENE
	ENSRNOT00000101922.1	UniProtKB/TrEMBL
Gene3D-CATH	2.20.100.10	UniProtKB/TrEMBL
	2.40.50.120	UniProtKB/TrEMBL
	2.60.120.830	UniProtKB/TrEMBL
	3.40.1620.60	UniProtKB/TrEMBL
InterPro	ADAMTS/ADAMTS-like	UniProtKB/TrEMBL
	ADAMTS_CR_3	UniProtKB/TrEMBL
	ADAMTS_spacer1	UniProtKB/TrEMBL
	Netrin_domain	UniProtKB/TrEMBL
	Netrin_module_non-TIMP	UniProtKB/TrEMBL
	Thrombospondin_1_rpt	UniProtKB/TrEMBL
	TIMP-like_OB-fold	UniProtKB/TrEMBL
	TSP1_rpt_sf	UniProtKB/TrEMBL
KEGG Report	rno:314626	UniProtKB/TrEMBL
NCBI Gene	314626	ENTREZGENE
PANTHER	ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE	UniProtKB/TrEMBL
	ADAMTS-LIKE PROTEIN 5	UniProtKB/TrEMBL
Pfam	ADAM_CR_3	UniProtKB/TrEMBL
	ADAM_spacer1	UniProtKB/TrEMBL
	NTR	UniProtKB/TrEMBL
	TSP_1	UniProtKB/TrEMBL
PhenoGen	Adamtsl5	PhenoGen
PRINTS	ADAMTSFAMILY	UniProtKB/TrEMBL
PROSITE	NTR	UniProtKB/TrEMBL
	TSP1	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000033787	RatGTEx
SMART	C345C	UniProtKB/TrEMBL
	TSP1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50242	UniProtKB/TrEMBL
	TSP1	UniProtKB/TrEMBL
UniProt	A0A8I6GJQ1	ENTREZGENE, UniProtKB/TrEMBL
	A6K8M0	ENTREZGENE, UniProtKB/TrEMBL
	A6K8M1	ENTREZGENE, UniProtKB/TrEMBL
	F1M9K2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Adamtsl5	ADAMTS-like 5	Adamtsl5_predicted	ADAMTS-like 5 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Adamtsl5_predicted	ADAMTS-like 5 (predicted)	Thsd6_predicted	thrombospondin, type I domain containing 6 (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-12	Thsd6_predicted	thrombospondin, type I domain containing 6 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar