Dnaja2 (DnaJ heat shock protein family (Hsp40) member A2) - Rat Genome Database

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Gene: Dnaja2 (DnaJ heat shock protein family (Hsp40) member A2) Rattus norvegicus
Analyze
Symbol: Dnaja2
Name: DnaJ heat shock protein family (Hsp40) member A2
RGD ID: 71001
Description: Predicted to enable ATPase activator activity; protein-folding chaperone binding activity; and unfolded protein binding activity. Involved in carbon tetrachloride metabolic process. Predicted to be located in membrane. Predicted to be active in cytosol. Biomarker of liver disease. Orthologous to human DNAJA2 (DnaJ heat shock protein family (Hsp40) member A2); PARTICIPATES IN androgen signaling pathway; cortisol signaling pathway; estrogen signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Cpr3; Dj3; DjA2; DnaJ (Hsp40) homolog, subfamily A, member 2; dnaJ homolog subfamily A member 2; Dnj3; Hirip4; MGC93325; Rdj2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81937,671,019 - 37,689,163 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1937,670,945 - 37,690,120 (+)EnsemblGRCr8
mRatBN7.21921,497,792 - 21,516,904 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1921,497,729 - 21,516,901 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1923,187,280 - 23,205,448 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01928,381,803 - 28,399,971 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01931,344,590 - 31,362,759 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01922,569,999 - 22,588,143 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1922,569,999 - 22,588,137 (+)Ensemblrn6Rnor6.0
Rnor_5.01933,576,436 - 33,594,580 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41922,853,702 - 22,871,846 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1921,358,547 - 21,376,691 (+)NCBICelera
RGSC_v3.11922,858,527 - 22,876,671 (+)NCBI
Cytogenetic Map19p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,4-dihydrocoumarin  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
aniline  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
cobalt dichloride  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
ethanol  (ISO)
fenofibrate  (EXP,ISO)
fluoxetine  (EXP)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
hypochlorous acid  (ISO)
indometacin  (EXP,ISO)
ivermectin  (ISO)
kojic acid  (EXP)
limonene  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mercury atom  (EXP)
mercury(0)  (EXP)
Mesaconitine  (EXP)
methimazole  (EXP)
methoxychlor  (EXP)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nitrates  (ISO)
Nutlin-3  (ISO)
ochratoxin A  (ISO)
oxidopamine  (EXP)
ozone  (EXP)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
phlorizin  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
Rebamipide  (EXP)
resveratrol  (ISO)
rotenone  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sulfasalazine  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
uranium atom  (ISO)
valproic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,IEA,ISO)
membrane  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Expression cloning of a novel farnesylated protein, RDJ2, encoding a DnaJ protein homologue. Andres DA, etal., Arch Biochem Biophys 1997 Oct 1;346(1):113-24.
2. Rdj2, a J protein family member, interacts with cellular prion PrP(C). Beck KE, etal., Biochem Biophys Res Commun. 2006 Aug 4;346(3):866-71. Epub 2006 Jun 6.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Induction of molecular chaperones in carbon tetrachloride-treated rat liver: implications in protection against liver damage. Lee KJ, etal., Cell Stress Chaperones. 2004 Mar;9(1):58-68.
6. Gene Data Set MGD Curation, June 12, 2002
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. Chaperoning of glucocorticoid receptors. Pratt WB, etal., Handb Exp Pharmacol. 2006;(172):111-38.
10. Molecular chaperones throughout the life cycle of the androgen receptor. Prescott J and Coetzee GA, Cancer Lett. 2006 Jan 8;231(1):12-9.
11. GOA pipeline RGD automated data pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Comprehensive gene review and curation RGD comprehensive gene curation
14. Minireview: the intersection of steroid receptors with molecular chaperones: observations and questions. Smith DF and Toft DO, Mol Endocrinol. 2008 Oct;22(10):2229-40. Epub 2008 May 1.
15. Human DnaJ homologs dj2 and dj3, and bag-1 are positive cochaperones of hsc70. Terada K and Mori M, J Biol Chem. 2000 Aug 11;275(32):24728-34.
Additional References at PubMed
PMID:12477932   PMID:16169070   PMID:18595009   PMID:19056867   PMID:21231916   PMID:22871113   PMID:24318877   PMID:25002582   PMID:30053369  


Genomics

Comparative Map Data
Dnaja2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81937,671,019 - 37,689,163 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1937,670,945 - 37,690,120 (+)EnsemblGRCr8
mRatBN7.21921,497,792 - 21,516,904 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1921,497,729 - 21,516,901 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1923,187,280 - 23,205,448 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01928,381,803 - 28,399,971 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01931,344,590 - 31,362,759 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01922,569,999 - 22,588,143 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1922,569,999 - 22,588,137 (+)Ensemblrn6Rnor6.0
Rnor_5.01933,576,436 - 33,594,580 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41922,853,702 - 22,871,846 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1921,358,547 - 21,376,691 (+)NCBICelera
RGSC_v3.11922,858,527 - 22,876,671 (+)NCBI
Cytogenetic Map19p11NCBI
DNAJA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381646,955,362 - 46,973,674 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1646,955,362 - 46,973,704 (-)Ensemblhg38GRCh38
GRCh371646,989,274 - 47,007,585 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361645,546,775 - 45,565,126 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341645,547,795 - 45,565,036NCBI
Celera1631,497,392 - 31,515,743 (-)NCBICelera
Cytogenetic Map16q11.2NCBI
HuRef1632,879,590 - 32,897,952 (-)NCBIHuRef
CHM1_11648,396,273 - 48,414,621 (-)NCBICHM1_1
T2T-CHM13v2.01652,752,176 - 52,770,493 (-)NCBIT2T-CHM13v2.0
Dnaja2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39886,264,262 - 86,281,990 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl886,264,262 - 86,281,973 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38885,537,633 - 85,555,361 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl885,537,633 - 85,555,344 (-)Ensemblmm10GRCm38
MGSCv37888,061,539 - 88,079,170 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36888,427,745 - 88,445,376 (-)NCBIMGSCv36mm8
Celera889,834,255 - 89,851,758 (-)NCBICelera
Cytogenetic Map8C3NCBI
cM Map841.61NCBI
Dnaja2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554748,180,995 - 8,202,267 (+)Ensembl
ChiLan1.0NW_0049554748,180,995 - 8,202,169 (+)NCBIChiLan1.0ChiLan1.0
DNAJA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21856,417,398 - 56,436,339 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11662,322,325 - 62,341,277 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01627,223,414 - 27,240,726 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11646,113,238 - 46,130,028 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1646,113,088 - 46,130,028 (-)EnsemblpanPan2panpan1.1
DNAJA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1267,903,292 - 67,916,267 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha264,478,251 - 64,494,696 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0268,460,779 - 68,477,225 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl268,460,772 - 68,477,787 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1265,273,419 - 65,289,848 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0266,296,767 - 66,313,250 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,288,195 - 67,304,637 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dnaja2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934959,238,017 - 59,254,800 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936475335,851 - 350,933 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936475334,275 - 351,051 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAJA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl637,591,916 - 37,608,361 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1637,584,012 - 37,606,198 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2632,929,182 - 32,943,460 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNAJA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1532,815,641 - 32,834,385 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604743,735,497 - 43,753,794 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnaja2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624914517,961 - 534,512 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624914518,593 - 534,527 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Dnaja2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11714,203,910 - 14,222,624 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dnaja2
37 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:42
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000022573
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19799775052997750Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)191922068964220689Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19799775052997750Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)19574806450748064Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)192409397369093973Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat
2303628Vencon9Ventilatory control QTL 90.005respiration trait (VT:0001943)minute ventilation (CMO:0000132)192318858668188586Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)193128753251431640Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19799775052997750Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19799775052997750Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
1554318Bmd5Bone mineral density QTL 512.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)192318858668188586Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)192010930665109306Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)193009938347207961Rat

Markers in Region
D16S2601E  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24156,135,401 - 156,135,533 (+)MAPPERmRatBN7.2
mRatBN7.21921,514,290 - 21,514,554 (+)MAPPERmRatBN7.2
Rnor_6.01922,586,494 - 22,586,757NCBIRnor6.0
Rnor_6.04155,741,444 - 155,741,575NCBIRnor6.0
Rnor_5.01933,592,931 - 33,593,194UniSTSRnor5.0
Rnor_5.04222,762,210 - 222,762,341UniSTSRnor5.0
RGSC_v3.44159,385,925 - 159,386,056UniSTSRGSC3.4
RGSC_v3.41922,870,197 - 22,870,460UniSTSRGSC3.4
Celera1921,375,042 - 21,375,305UniSTS
Celera4144,955,665 - 144,955,796UniSTS
Cytogenetic Map19q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000022573   ⟹   ENSRNOP00000022573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1937,670,945 - 37,690,120 (+)Ensembl
mRatBN7.2 Ensembl1921,497,729 - 21,516,901 (+)Ensembl
Rnor_6.0 Ensembl1922,569,999 - 22,588,137 (+)Ensembl
RefSeq Acc Id: NM_032079   ⟹   NP_114468
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81937,671,019 - 37,689,163 (+)NCBI
mRatBN7.21921,497,792 - 21,515,940 (+)NCBI
Rnor_6.01922,569,999 - 22,588,143 (+)NCBI
Rnor_5.01933,576,436 - 33,594,580 (+)NCBI
RGSC_v3.41922,853,702 - 22,871,846 (+)RGD
Celera1921,358,547 - 21,376,691 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_114468 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB64094 (Get FASTA)   NCBI Sequence Viewer  
  AAH87010 (Get FASTA)   NCBI Sequence Viewer  
  EDL87491 (Get FASTA)   NCBI Sequence Viewer  
  EDL87492 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022573
GenBank Protein O35824 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_114468   ⟸   NM_032079
- UniProtKB: O35824 (UniProtKB/Swiss-Prot),   Q5M9H7 (UniProtKB/TrEMBL),   F7F428 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022573   ⟸   ENSRNOT00000022573
Protein Domains
CR-type   J

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35824-F1-model_v2 AlphaFold O35824 1-412 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700990
Promoter ID:EPDNEW_R11513
Type:initiation region
Name:Dnaja2_1
Description:DnaJ heat shock protein family member A2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01922,569,905 - 22,569,965EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:71001 AgrOrtholog
BioCyc Gene G2FUF-6212 BioCyc
Ensembl Genes ENSRNOG00000016251 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000022573 ENTREZGENE
Gene3D-CATH 1.10.287.110 UniProtKB/Swiss-Prot
  Heat shock protein DnaJ, cysteine-rich domain UniProtKB/Swiss-Prot
  Urease metallochaperone UreE, N-terminal domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7191358 IMAGE-MGC_LOAD
InterPro DnaJ UniProtKB/Swiss-Prot
  DnaJ_C UniProtKB/Swiss-Prot
  DnaJ_domain UniProtKB/Swiss-Prot
  DnaJ_domain_CS UniProtKB/Swiss-Prot
  DNJA1/2-like UniProtKB/Swiss-Prot
  HSP40/DnaJ_pept-bd UniProtKB/Swiss-Prot
  HSP_DnaJ_Cys-rich_dom UniProtKB/Swiss-Prot
  HSP_DnaJ_Cys-rich_dom_sf UniProtKB/Swiss-Prot
  J_dom_sf UniProtKB/Swiss-Prot
MGC_CLONE MGC:93325 IMAGE-MGC_LOAD
NCBI Gene 84026 ENTREZGENE
PANTHER PTHR43888 UniProtKB/Swiss-Prot
Pfam DnaJ UniProtKB/Swiss-Prot
  DnaJ_C UniProtKB/Swiss-Prot
  DnaJ_CXXCXGXG UniProtKB/Swiss-Prot
PhenoGen Dnaja2 PhenoGen
PRINTS JDOMAIN UniProtKB/Swiss-Prot
PROSITE DNAJ_1 UniProtKB/Swiss-Prot
  DNAJ_2 UniProtKB/Swiss-Prot
  ZF_CR UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016251 RatGTEx
SMART DnaJ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46565 UniProtKB/Swiss-Prot
  SSF49493 UniProtKB/Swiss-Prot
  SSF57938 UniProtKB/Swiss-Prot
UniProt A6KDD5_RAT UniProtKB/TrEMBL
  DNJA2_RAT UniProtKB/Swiss-Prot
  F7F428 ENTREZGENE, UniProtKB/TrEMBL
  O35824 ENTREZGENE
  Q5M9H7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Dnaja2  DnaJ heat shock protein family (Hsp40) member A2  Dnaja2  DnaJ (Hsp40) homolog, subfamily A, member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-07-09 Dnaja2  DnaJ (Hsp40) homolog, subfamily A, member 2      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression ubiquitously expressed 70722
gene_product member of the DnaJ-related proteins 70722