Plcb4 (phospholipase C, beta 4) - Rat Genome Database

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Gene: Plcb4 (phospholipase C, beta 4) Rattus norvegicus
Analyze
Symbol: Plcb4
Name: phospholipase C, beta 4
RGD ID: 3345
Description: Enables mitogen-activated protein kinase binding activity. Involved in negative regulation of potassium ion transport. Predicted to be located in dendrite; nucleus; and plasma membrane. Predicted to be active in several cellular components, including glutamatergic synapse; parallel fiber to Purkinje cell synapse; and postsynaptic density. Orthologous to human PLCB4 (phospholipase C beta 4); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; protein kinase C (PKC) signaling pathway; Alzheimer's disease pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4; Beta4aa; phosphoinositide phospholipase C; phosphoinositide phospholipase C-beta-4; Phospholipase C (BETA4); Phospholipase C beta4; phospholipase C-beta-4; PLC-beta-4; RATBETA4AA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Plcb4_v1 ; Plcb4_v2
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83143,405,721 - 143,775,129 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3143,405,950 - 143,775,113 (+)EnsemblGRCr8
mRatBN7.23122,952,965 - 123,322,522 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3122,953,196 - 123,322,392 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3126,861,256 - 127,230,065 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03135,448,283 - 135,807,045 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03133,116,870 - 133,485,687 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03128,601,163 - 128,971,720 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3128,756,799 - 128,971,746 (+)Ensemblrn6Rnor6.0
Rnor_5.03135,089,551 - 135,459,248 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43123,706,313 - 124,077,381 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3121,694,557 - 122,062,160 (+)NCBICelera
RGSC_v3.13123,611,885 - 123,982,941 (+)NCBI
Cytogenetic Map3q36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-pilocarpine  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
1,3-dinitrobenzene  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
6-propyl-2-thiouracil  (EXP)
aconitine  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aflatoxin M1  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
asbestos  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
crocidolite asbestos  (ISO)
decabromodiphenyl ether  (EXP)
dextran sulfate  (ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
fingolimod hydrochloride  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
FR900359  (ISO)
hexachlorophene  (ISO)
hydrogen cyanide  (ISO)
isoprenaline  (ISO)
malathion  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
mitoxantrone  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nickel atom  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenylarsine oxide  (ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
propiconazole  (EXP)
selenium atom  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
sphingosine 1-phosphate  (ISO)
succimer  (ISO)
sunitinib  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
topotecan  (EXP)
tributylstannane  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)
XL147  (ISO)
zinc atom  (EXP)
zinc sulfate  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. A unique isoform of phospholipase Cbeta4 highly expressed in the cerebellum and eye. Adamski FM, etal., Biochim Biophys Acta 1999 Jan 18;1444(1):55-60.
2. Fear conditioning is associated with altered integration of PLC and ERK signaling in the hippocampus. Buckley CT and Caldwell KK, Pharmacol Biochem Behav. 2004 Dec;79(4):633-40.
3. Stimulation of 5-HT(2) receptors in prefrontal pyramidal neurons inhibits Ca(v)1.2 L type Ca(2+) currents via a PLCbeta/IP3/calcineurin signaling cascade. Day M, etal., J Neurophysiol 2002 May;87(5):2490-504.
4. Stimulation of phospholipase Cbeta by membrane interactions, interdomain movement, and G protein binding--how many ways can you activate an enzyme? Drin G and Scarlata S, Cell Signal. 2007 Jul;19(7):1383-92. Epub 2007 Apr 29.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Bradykinin, but not muscarinic, inhibition of M-current in rat sympathetic ganglion neurons involves phospholipase C-beta 4. Haley JE, etal., J Neurosci. 2000 Nov 1;20(21):RC105.
7. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
8. Cloning of cDNA encoding rat phospholipase C-beta 4, a new member of the phospholipase C. Kim MJ, etal., Biochem Biophys Res Commun 1993 Jul 30;194(2):706-12.
9. A cytosolic, galphaq- and betagamma-insensitive splice variant of phospholipase C-beta4. Kim MJ, etal., J Biol Chem 1998 Feb 6;273(6):3618-24.
10. Purification, molecular cloning, and sequencing of phospholipase C-beta 4. Lee CW, etal., J Biol Chem 1993 Oct 5;268(28):21318-27.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
14. Translation of clock rhythmicity into neural firing in suprachiasmatic nucleus requires mGluR-PLCbeta4 signaling. Park D, etal., Nat Neurosci 2003 Apr;6(4):337-8.
15. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
16. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
17. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
18. Regulation of phosphoinositide-specific phospholipase C. Rhee SG Annu Rev Biochem. 2001;70:281-312.
19. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:11551922   PMID:15579147   PMID:15738151   PMID:19826069   PMID:19856080   PMID:23503970  


Genomics

Comparative Map Data
Plcb4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83143,405,721 - 143,775,129 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3143,405,950 - 143,775,113 (+)EnsemblGRCr8
mRatBN7.23122,952,965 - 123,322,522 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3122,953,196 - 123,322,392 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3126,861,256 - 127,230,065 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03135,448,283 - 135,807,045 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03133,116,870 - 133,485,687 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03128,601,163 - 128,971,720 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3128,756,799 - 128,971,746 (+)Ensemblrn6Rnor6.0
Rnor_5.03135,089,551 - 135,459,248 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43123,706,313 - 124,077,381 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3121,694,557 - 122,062,160 (+)NCBICelera
RGSC_v3.13123,611,885 - 123,982,941 (+)NCBI
Cytogenetic Map3q36NCBI
PLCB4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38209,068,678 - 9,480,808 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl209,067,825 - 9,504,593 (+)Ensemblhg38GRCh38
GRCh37209,049,325 - 9,461,455 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36209,024,932 - 9,409,463 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34209,024,931 - 9,409,460NCBI
Celera209,119,817 - 9,531,474 (+)NCBICelera
Cytogenetic Map20p12.3-p12.2NCBI
HuRef209,001,542 - 9,413,398 (+)NCBIHuRef
CHM1_1209,050,899 - 9,462,613 (+)NCBICHM1_1
T2T-CHM13v2.0209,111,633 - 9,523,716 (+)NCBIT2T-CHM13v2.0
Plcb4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392135,500,523 - 135,856,522 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2135,500,931 - 135,856,513 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382135,658,603 - 136,014,602 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2135,659,011 - 136,014,593 (+)Ensemblmm10GRCm38
MGSCv372135,567,566 - 135,838,804 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362135,433,271 - 135,704,509 (+)NCBIMGSCv36mm8
Celera2136,939,191 - 137,211,347 (+)NCBICelera
Cytogenetic Map2F3NCBI
cM Map266.64NCBI
Plcb4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541519,310,917 - 19,463,098 (+)Ensembl
ChiLan1.0NW_00495541519,108,120 - 19,462,084 (+)NCBIChiLan1.0ChiLan1.0
PLCB4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2219,967,849 - 10,403,434 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1209,964,676 - 10,400,261 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0209,042,127 - 9,454,207 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1208,846,152 - 9,456,443 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl209,192,061 - 9,456,443 (+)EnsemblpanPan2panpan1.1
PLCB4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12412,750,631 - 13,169,697 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2412,752,083 - 13,169,745 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2412,575,552 - 12,993,940 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02413,157,425 - 13,576,878 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2413,157,425 - 13,576,868 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12412,769,385 - 13,187,876 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02412,868,981 - 13,288,064 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02413,206,767 - 13,626,337 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Plcb4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640161,560,396 - 161,921,708 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364859,991,299 - 10,353,123 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364859,991,731 - 10,353,231 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCB4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1717,916,110 - 18,402,532 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11717,915,984 - 18,402,540 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21720,428,956 - 20,770,454 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLCB4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1228,650,604 - 29,059,435 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl228,650,421 - 28,915,290 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607115,510,020 - 15,919,543 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plcb4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474110,277,805 - 10,430,327 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474110,047,899 - 10,435,088 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Plcb4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15115,514,450 - 115,654,224 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Plcb4
2189 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:626
Count of miRNA genes:187
Interacting mature miRNAs:226
Transcripts:ENSRNOT00000042853, ENSRNOT00000045393, ENSRNOT00000049855
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
7387306Bw124Body weight QTL 1243.20.0003body mass (VT:0001259)body weight (CMO:0000012)3104545086149545086Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3141508991166376254Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)3112250810157250810Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)3117537367162537367Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3125116475170116475Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3110225882155225882Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3136091420155634702Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3122395989167395989Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)3131036586176036586Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)3131036586176036586Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)398651826167012663Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3110634702155634702Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)3116188400161188400Rat

Markers in Region
D3Wox21  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23123,321,035 - 123,321,202 (+)MAPPERmRatBN7.2
Rnor_6.03128,970,363 - 128,970,529NCBIRnor6.0
Rnor_5.03135,457,891 - 135,458,057UniSTSRnor5.0
RGSC_v3.43124,076,024 - 124,076,190UniSTSRGSC3.4
Celera3122,060,803 - 122,060,969UniSTS
Cytogenetic Map3q36UniSTS
D3Rat112  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23123,217,730 - 123,217,913 (+)MAPPERmRatBN7.2
Rnor_6.03128,867,047 - 128,867,229NCBIRnor6.0
Rnor_5.03135,354,182 - 135,354,364UniSTSRnor5.0
RGSC_v3.43123,971,720 - 123,971,902UniSTSRGSC3.4
RGSC_v3.43123,971,719 - 123,971,902RGDRGSC3.4
Celera3121,956,650 - 121,956,832UniSTS
RGSC_v3.13123,877,293 - 123,877,475RGD
RH 3.4 Map31081.6UniSTS
RH 3.4 Map31081.6RGD
RH 2.0 Map3724.8RGD
SHRSP x BN Map360.7499RGD
Cytogenetic Map3q36UniSTS
D3Rat157  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83143,520,350 - 143,520,503 (+)Marker Load Pipeline
mRatBN7.23123,067,607 - 123,067,760 (+)MAPPERmRatBN7.2
Rnor_6.03128,716,357 - 128,716,509NCBIRnor6.0
Rnor_5.03135,204,992 - 135,205,144UniSTSRnor5.0
RGSC_v3.43123,822,201 - 123,822,354RGDRGSC3.4
RGSC_v3.43123,822,202 - 123,822,354UniSTSRGSC3.4
Celera3121,808,597 - 121,808,709UniSTS
RGSC_v3.13123,727,775 - 123,727,927RGD
RH 3.4 Map31079.6RGD
RH 3.4 Map31079.6UniSTS
RH 2.0 Map3721.1RGD
SHRSP x BN Map360.7899RGD
FHH x ACI Map376.92RGD
Cytogenetic Map3q36UniSTS
D3Rat255  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23122,980,747 - 122,980,996 (+)MAPPERmRatBN7.2
Rnor_6.03128,628,848 - 128,629,098NCBIRnor6.0
Rnor_5.03135,117,504 - 135,117,754UniSTSRnor5.0
RGSC_v3.43123,734,009 - 123,734,258RGDRGSC3.4
RGSC_v3.43123,734,008 - 123,734,258UniSTSRGSC3.4
Celera3121,722,146 - 121,722,386UniSTS
RGSC_v3.13123,639,335 - 123,639,846RGD
SHRSP x BN Map359.6699RGD
SHRSP x BN Map359.6699UniSTS
Cytogenetic Map3q36UniSTS
RH143113  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83143,690,824 - 143,690,950 (+)Marker Load Pipeline
mRatBN7.23123,238,090 - 123,238,217 (+)MAPPERmRatBN7.2
Rnor_6.03128,887,410 - 128,887,536NCBIRnor6.0
Rnor_5.03135,374,545 - 135,374,671UniSTSRnor5.0
RGSC_v3.43123,992,083 - 123,992,209UniSTSRGSC3.4
Celera3121,977,081 - 121,977,207UniSTS
RH 3.4 Map31084.4UniSTS
Cytogenetic Map3q36UniSTS
AW534127  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83143,591,979 - 143,592,128 (+)Marker Load Pipeline
mRatBN7.23123,139,242 - 123,139,391 (+)MAPPERmRatBN7.2
Rnor_6.03128,788,971 - 128,789,119NCBIRnor6.0
Rnor_5.03135,276,034 - 135,276,182UniSTSRnor5.0
RGSC_v3.43123,893,184 - 123,893,332UniSTSRGSC3.4
Celera3121,878,575 - 121,878,723UniSTS
RH 3.4 Map31081.6UniSTS
Cytogenetic Map3q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
17 13 81 204 91 90 59 124 59 6 430 243 17 187 103 117 31 34 34

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001431415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_024353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283132 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF027571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF031370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY011767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L15556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L18962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U57836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000042853   ⟹   ENSRNOP00000048553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3143,406,021 - 143,775,113 (+)Ensembl
mRatBN7.2 Ensembl3123,107,067 - 123,322,377 (+)Ensembl
Rnor_6.0 Ensembl3128,756,799 - 128,971,704 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000045393   ⟹   ENSRNOP00000045972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3143,405,950 - 143,775,108 (+)Ensembl
mRatBN7.2 Ensembl3123,178,791 - 123,322,392 (+)Ensembl
Rnor_6.0 Ensembl3128,828,331 - 128,971,746 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000049855   ⟹   ENSRNOP00000048775
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3143,559,808 - 143,763,149 (+)Ensembl
mRatBN7.2 Ensembl3123,107,067 - 123,321,123 (+)Ensembl
Rnor_6.0 Ensembl3128,756,799 - 128,970,450 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095786   ⟹   ENSRNOP00000091621
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3143,406,021 - 143,775,113 (+)Ensembl
mRatBN7.2 Ensembl3123,107,067 - 123,322,377 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097572   ⟹   ENSRNOP00000087693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3143,633,922 - 143,775,108 (+)Ensembl
mRatBN7.2 Ensembl3122,953,196 - 123,320,907 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105709   ⟹   ENSRNOP00000076875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3143,405,950 - 143,775,108 (+)Ensembl
mRatBN7.2 Ensembl3123,040,696 - 123,322,383 (+)Ensembl
RefSeq Acc Id: NM_024353   ⟹   NP_077329
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,973 - 143,775,124 (+)NCBI
mRatBN7.23122,953,220 - 123,322,393 (+)NCBI
Rnor_6.03128,601,330 - 128,971,720 (+)NCBI
Rnor_5.03135,089,551 - 135,459,248 (+)NCBI
RGSC_v3.43123,706,313 - 124,077,381 (+)RGD
Celera3121,694,557 - 122,062,160 (+)RGD
Sequence:
RefSeq Acc Id: XM_006235083   ⟹   XP_006235145
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,406,022 - 143,775,129 (+)NCBI
mRatBN7.23122,953,169 - 123,320,907 (+)NCBI
Rnor_6.03128,601,284 - 128,971,720 (+)NCBI
Rnor_5.03135,089,551 - 135,459,248 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235085   ⟹   XP_006235147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,782 - 143,775,129 (+)NCBI
mRatBN7.23122,952,965 - 123,320,907 (+)NCBI
Rnor_6.03128,601,163 - 128,971,720 (+)NCBI
Rnor_5.03135,089,551 - 135,459,248 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235088   ⟹   XP_006235150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,515,131 - 143,775,129 (+)NCBI
mRatBN7.23123,060,160 - 123,320,907 (+)NCBI
Rnor_6.03128,711,100 - 128,971,720 (+)NCBI
Rnor_5.03135,089,551 - 135,459,248 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235094   ⟹   XP_006235156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,406,022 - 143,775,129 (+)NCBI
mRatBN7.23122,953,307 - 123,321,152 (+)NCBI
Rnor_6.03128,601,284 - 128,971,720 (+)NCBI
Rnor_5.03135,089,551 - 135,459,248 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039104317   ⟹   XP_038960245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,406,022 - 143,775,129 (+)NCBI
mRatBN7.23122,953,169 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104319   ⟹   XP_038960247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,523,410 - 143,775,129 (+)NCBI
mRatBN7.23123,070,667 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104320   ⟹   XP_038960248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,479,865 - 143,775,129 (+)NCBI
mRatBN7.23123,027,100 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104321   ⟹   XP_038960249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,934 - 143,775,129 (+)NCBI
mRatBN7.23122,953,169 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104322   ⟹   XP_038960250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,406,035 - 143,775,129 (+)NCBI
mRatBN7.23122,953,169 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104323   ⟹   XP_038960251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,934 - 143,775,129 (+)NCBI
mRatBN7.23122,953,169 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104324   ⟹   XP_038960252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,515,131 - 143,775,129 (+)NCBI
mRatBN7.23123,060,160 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104325   ⟹   XP_038960253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,786 - 143,775,129 (+)NCBI
mRatBN7.23122,952,965 - 123,320,907 (+)NCBI
RefSeq Acc Id: XM_039104328   ⟹   XP_038960256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,699,917 - 143,775,129 (+)NCBI
mRatBN7.23123,247,184 - 123,322,522 (+)NCBI
RefSeq Acc Id: XM_063283129   ⟹   XP_063139199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,721 - 143,775,129 (+)NCBI
RefSeq Acc Id: XM_063283130   ⟹   XP_063139200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,523,410 - 143,775,129 (+)NCBI
RefSeq Acc Id: XM_063283131   ⟹   XP_063139201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,782 - 143,775,129 (+)NCBI
RefSeq Acc Id: XM_063283132   ⟹   XP_063139202
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,721 - 143,775,129 (+)NCBI
RefSeq Acc Id: XM_063283133   ⟹   XP_063139203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,515,131 - 143,775,129 (+)NCBI
RefSeq Acc Id: XM_063283134   ⟹   XP_063139204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,405,932 - 143,775,129 (+)NCBI
RefSeq Acc Id: XM_063283135   ⟹   XP_063139205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,406,022 - 143,775,129 (+)NCBI
RefSeq Acc Id: XM_063283136   ⟹   XP_063139206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83143,406,022 - 143,775,129 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001418344 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418345 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418346 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418347 (Get FASTA)   NCBI Sequence Viewer  
  NP_001418348 (Get FASTA)   NCBI Sequence Viewer  
  NP_077329 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235145 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235147 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235150 (Get FASTA)   NCBI Sequence Viewer  
  XP_006235156 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960245 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960247 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960248 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960249 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960250 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960251 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960252 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960253 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960256 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139199 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139200 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139201 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139202 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139203 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139204 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139205 (Get FASTA)   NCBI Sequence Viewer  
  XP_063139206 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC24984 (Get FASTA)   NCBI Sequence Viewer  
  AAC98145 (Get FASTA)   NCBI Sequence Viewer  
  AAD10403 (Get FASTA)   NCBI Sequence Viewer  
  AAK13557 (Get FASTA)   NCBI Sequence Viewer  
  EDL80292 (Get FASTA)   NCBI Sequence Viewer  
  EDL80293 (Get FASTA)   NCBI Sequence Viewer  
  EDL80295 (Get FASTA)   NCBI Sequence Viewer  
  EDL80296 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000045972
  ENSRNOP00000048553
  ENSRNOP00000076875
  ENSRNOP00000087693
GenBank Protein Q9QW07 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_077329   ⟸   NM_024353
- UniProtKB: Q9Z0G6 (UniProtKB/Swiss-Prot),   Q9QW07 (UniProtKB/Swiss-Prot),   O88356 (UniProtKB/Swiss-Prot),   F1LNK2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235147   ⟸   XM_006235085
- Peptide Label: isoform X1
- UniProtKB: D4A8C5 (UniProtKB/TrEMBL),   A0A8I5Y961 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235145   ⟸   XM_006235083
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006235156   ⟸   XM_006235094
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006235150   ⟸   XM_006235088
- Peptide Label: isoform X1
- UniProtKB: D4A8C5 (UniProtKB/TrEMBL),   A0A8I5Y961 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000045972   ⟸   ENSRNOT00000045393
Ensembl Acc Id: ENSRNOP00000048775   ⟸   ENSRNOT00000049855
Ensembl Acc Id: ENSRNOP00000048553   ⟸   ENSRNOT00000042853
RefSeq Acc Id: XP_038960253   ⟸   XM_039104325
- Peptide Label: isoform X1
- UniProtKB: D4A8C5 (UniProtKB/TrEMBL),   A0A8I5Y961 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960245   ⟸   XM_039104317
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038960250   ⟸   XM_039104322
- Peptide Label: isoform X1
- UniProtKB: D4A8C5 (UniProtKB/TrEMBL),   A0A8I5Y961 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960251   ⟸   XM_039104323
- Peptide Label: isoform X1
- UniProtKB: D4A8C5 (UniProtKB/TrEMBL),   A0A8I5Y961 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960249   ⟸   XM_039104321
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038960248   ⟸   XM_039104320
- Peptide Label: isoform X1
- UniProtKB: D4A8C5 (UniProtKB/TrEMBL),   A0A8I5Y961 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960252   ⟸   XM_039104324
- Peptide Label: isoform X1
- UniProtKB: D4A8C5 (UniProtKB/TrEMBL),   A0A8I5Y961 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960247   ⟸   XM_039104319
- Peptide Label: isoform X1
- UniProtKB: D4A8C5 (UniProtKB/TrEMBL),   A0A8I5Y961 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038960256   ⟸   XM_039104328
- Peptide Label: isoform X5
Ensembl Acc Id: ENSRNOP00000091621   ⟸   ENSRNOT00000095786
Ensembl Acc Id: ENSRNOP00000076875   ⟸   ENSRNOT00000105709
Ensembl Acc Id: ENSRNOP00000087693   ⟸   ENSRNOT00000097572
RefSeq Acc Id: XP_063139199   ⟸   XM_063283129
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y961 (UniProtKB/TrEMBL),   D4A8C5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139202   ⟸   XM_063283132
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y961 (UniProtKB/TrEMBL),   D4A8C5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139201   ⟸   XM_063283131
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y961 (UniProtKB/TrEMBL),   D4A8C5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139204   ⟸   XM_063283134
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y961 (UniProtKB/TrEMBL),   A6HQJ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139206   ⟸   XM_063283136
- Peptide Label: isoform X3
- UniProtKB: Q9Z0G6 (UniProtKB/Swiss-Prot),   Q9QW07 (UniProtKB/Swiss-Prot),   O88356 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063139205   ⟸   XM_063283135
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063139203   ⟸   XM_063283133
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y961 (UniProtKB/TrEMBL),   A6HQJ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139200   ⟸   XM_063283130
- Peptide Label: isoform X1
- UniProtKB: A0A8I5Y961 (UniProtKB/TrEMBL),   D4A8C5 (UniProtKB/TrEMBL)
Protein Domains
C2   PI-PLC X-box   PI-PLC Y-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QW07-F1-model_v2 AlphaFold Q9QW07 1-1175 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3345 AgrOrtholog
BioCyc Gene G2FUF-47732 BioCyc
BioCyc Pathway PWY-6351 [D-myo-inositol (1,4,5)-trisphosphate biosynthesis] BioCyc
  PWY-6367 [D-myo-inositol-5-phosphate metabolism] BioCyc
  PWY-8052 [2-arachidonoylglycerol biosynthesis] BioCyc
BioCyc Pathway Image PWY-6351 BioCyc
  PWY-6367 BioCyc
  PWY-8052 BioCyc
Ensembl Genes ENSRNOG00000033119 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000042853 ENTREZGENE
  ENSRNOT00000045393 ENTREZGENE
  ENSRNOT00000097572 ENTREZGENE
  ENSRNOT00000105709 ENTREZGENE
Gene3D-CATH 1.20.1230.10 UniProtKB/Swiss-Prot
  2.30.29.240 UniProtKB/Swiss-Prot
  2.60.40.150 UniProtKB/Swiss-Prot
  3.20.20.190 UniProtKB/Swiss-Prot
  EF-hand UniProtKB/Swiss-Prot
InterPro C2_dom UniProtKB/Swiss-Prot
  C2_domain_sf UniProtKB/Swiss-Prot
  EF-hand-dom_pair UniProtKB/Swiss-Prot
  PI-PLC_fam UniProtKB/Swiss-Prot
  PLC-beta UniProtKB/Swiss-Prot
  PLC-beta_C UniProtKB/Swiss-Prot
  PLC-beta_C_sf UniProtKB/Swiss-Prot
  PLC-beta_PH UniProtKB/Swiss-Prot
  PLC-like_Pdiesterase_TIM-brl UniProtKB/Swiss-Prot
  PLCB1-4-like_EFh UniProtKB/Swiss-Prot
  PLipase_C_PInositol-sp_X_dom UniProtKB/Swiss-Prot
  PLipase_C_Pinositol-sp_Y UniProtKB/Swiss-Prot
KEGG Report rno:25031 UniProtKB/Swiss-Prot
NCBI Gene 25031 ENTREZGENE
PANTHER 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4 UniProtKB/Swiss-Prot
  PTHR10336 UniProtKB/Swiss-Prot
Pfam PF00168 UniProtKB/Swiss-Prot
  PH_14 UniProtKB/Swiss-Prot
  PI-PLC-X UniProtKB/Swiss-Prot
  PI-PLC-Y UniProtKB/Swiss-Prot
  PLC-beta_C UniProtKB/Swiss-Prot
  PLCB1-4-like_EFh UniProtKB/Swiss-Prot
PhenoGen Plcb4 PhenoGen
PIRSF PLC-beta UniProtKB/Swiss-Prot
PRINTS PHPHLIPASEC UniProtKB/Swiss-Prot
PROSITE PIPLC_X_DOMAIN UniProtKB/Swiss-Prot
  PIPLC_Y_DOMAIN UniProtKB/Swiss-Prot
  PS50004 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000033119 RatGTEx
SMART PLCXc UniProtKB/Swiss-Prot
  PLCYc UniProtKB/Swiss-Prot
  SM00239 UniProtKB/Swiss-Prot
Superfamily-SCOP C-terminal domain of PLC-beta UniProtKB/Swiss-Prot
  PH domain-like UniProtKB/Swiss-Prot
  SSF47473 UniProtKB/Swiss-Prot
  SSF49562 UniProtKB/Swiss-Prot
  SSF51695 UniProtKB/Swiss-Prot
TIGR TC217862
UniProt A0A8I5Y961 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A4W1_RAT UniProtKB/TrEMBL
  A0A8I6AGH0_RAT UniProtKB/TrEMBL
  A6HQJ1 ENTREZGENE, UniProtKB/TrEMBL
  A6HQJ4 ENTREZGENE, UniProtKB/TrEMBL
  D3ZCI6_RAT UniProtKB/TrEMBL
  D4A8C5 ENTREZGENE, UniProtKB/TrEMBL
  F1LNK2 ENTREZGENE, UniProtKB/TrEMBL
  O88356 ENTREZGENE
  PLCB4_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9Z0G6 ENTREZGENE
UniProt Secondary O88356 UniProtKB/Swiss-Prot
  Q9Z0G6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Plcb4  Phospholipase C , beta4      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_homology has 50% amino acid identity with D. melanogastar norpA 633574