Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of ANKRA2 mRNA | CTD | PMID:23649840 | 1,2-dimethylhydrazine | multiple interactions | ISO | Ankra2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANKRA2 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | affects expression | ISO | Ankra2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine affects the expression of ANKRA2 mRNA | CTD | PMID:22206623 | 17beta-estradiol | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of ANKRA2 mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Ankra2 (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of ANKRA2 mRNA] | CTD | PMID:15034205 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ANKRA2 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Ankra2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ANKRA2 mRNA | CTD | PMID:15034205 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of ANKRA2 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of ANKRA2 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of ANKRA2 mRNA | CTD | PMID:30851411 | 2-methylcholine | affects expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of ANKRA2 mRNA | CTD | PMID:21179406 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of ANKRA2 mRNA | CTD | PMID:24780913 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of ANKRA2 mRNA | CTD | PMID:30047161 | aflatoxin B1 | affects expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of ANKRA2 protein | CTD | PMID:20106945 | aflatoxin B1 | decreases methylation | ISO | ANKRA2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ANKRA2 gene | CTD | PMID:27153756 | aflatoxin B1 | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of ANKRA2 mRNA | CTD | PMID:21632981 more ... | aflatoxin B1 | increases expression | ISO | Ankra2 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of ANKRA2 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ANKRA2 mRNA | CTD | PMID:23724009 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of ANKRA2 mRNA | CTD | PMID:30047161 | benzo[a]pyrene | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of ANKRA2 mRNA | CTD | PMID:20064835 more ... | benzo[a]pyrene | increases expression | ISO | Ankra2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of ANKRA2 mRNA | CTD | PMID:15034205 | benzo[a]pyrene | multiple interactions | ISO | Ankra2 (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Benzo(a)pyrene results in increased expression of ANKRA2 mRNA] | CTD | PMID:15034205 | benzo[a]pyrene diol epoxide I | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 and PMID:26238291 | bis(2-chloroethyl) sulfide | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Mustard Gas results in increased expression of ANKRA2 mRNA | CTD | PMID:25102026 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ANKRA2 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ANKRA2 mRNA | CTD | PMID:34947998 | carbon nanotube | decreases expression | ISO | Ankra2 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | ANKRA2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ANKRA2 gene] | CTD | PMID:28238834 | chloroacetaldehyde | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | chloroacetaldehyde results in decreased expression of ANKRA2 mRNA | CTD | PMID:25596134 | cidofovir anhydrous | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Cidofovir results in decreased expression of ANKRA2 mRNA | CTD | PMID:25596134 | cisplatin | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of ANKRA2 mRNA | CTD | PMID:25596134 | cisplatin | multiple interactions | ISO | ANKRA2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of ANKRA2 mRNA | CTD | PMID:27392435 | cisplatin | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of ANKRA2 mRNA | CTD | PMID:27392435 | clodronic acid | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Clodronic Acid results in decreased expression of ANKRA2 mRNA | CTD | PMID:25596134 | cyclosporin A | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of ANKRA2 mRNA | CTD | PMID:25596134 | dicrotophos | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of ANKRA2 mRNA | CTD | PMID:28302478 | dioxygen | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Oxygen deficiency results in decreased expression of ANKRA2 mRNA | CTD | PMID:25596134 | disodium selenite | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of ANKRA2 mRNA | CTD | PMID:24383545 | dorsomorphin | multiple interactions | ISO | ANKRA2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ANKRA2 mRNA | CTD | PMID:27188386 | elemental selenium | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Selenium results in decreased expression of ANKRA2 mRNA | CTD | PMID:19244175 | ethanol | affects splicing | ISO | Ankra2 (Mus musculus) | 6480464 | Ethanol affects the splicing of ANKRA2 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of ANKRA2 mRNA | CTD | PMID:23649840 | fenofibrate | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Fenofibrate results in increased expression of ANKRA2 mRNA | CTD | PMID:25596134 | folic acid | multiple interactions | ISO | ANKRA2 (Homo sapiens) | 6480464 | [Folic Acid deficiency co-treated with Methotrexate] results in increased expression of ANKRA2 mRNA | CTD | PMID:24657277 | folic acid | multiple interactions | ISO | Ankra2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ANKRA2 mRNA | CTD | PMID:22206623 | formaldehyde | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of ANKRA2 mRNA | CTD | PMID:23649840 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of ANKRA2 mRNA | CTD | PMID:33387578 | hydrogen peroxide | affects expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of ANKRA2 mRNA | CTD | PMID:23410634 | ifosfamide | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Ifosfamide results in decreased expression of ANKRA2 mRNA | CTD | PMID:25596134 | lead(0) | affects expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Lead affects the expression of ANKRA2 mRNA | CTD | PMID:28903495 | menadione | affects expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of ANKRA2 mRNA | CTD | PMID:23410634 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of ANKRA2 mRNA | CTD | PMID:30047161 | methotrexate | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of ANKRA2 mRNA | CTD | PMID:24657277 | methotrexate | multiple interactions | ISO | ANKRA2 (Homo sapiens) | 6480464 | [Folic Acid deficiency co-treated with Methotrexate] results in increased expression of ANKRA2 mRNA | CTD | PMID:24657277 | methyl methanesulfonate | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of ANKRA2 mRNA | CTD | PMID:23649840 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ANKRA2 mRNA | CTD | PMID:33387578 | potassium chromate | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of ANKRA2 mRNA | CTD | PMID:22714537 | quercetin | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Quercetin results in increased expression of ANKRA2 mRNA | CTD | PMID:21632981 | rac-lactic acid | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of ANKRA2 mRNA | CTD | PMID:30851411 | SB 431542 | multiple interactions | ISO | ANKRA2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ANKRA2 mRNA | CTD | PMID:27188386 | selenium atom | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Selenium results in decreased expression of ANKRA2 mRNA | CTD | PMID:19244175 | silicon dioxide | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of ANKRA2 mRNA | CTD | PMID:25895662 | simvastatin | increases expression | EXP | | 6480464 | Simvastatin results in increased expression of ANKRA2 mRNA | CTD | PMID:25055962 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of ANKRA2 mRNA | CTD | PMID:30047161 | tert-butyl hydroperoxide | affects expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide affects the expression of ANKRA2 mRNA | CTD | PMID:23410634 | triptonide | increases expression | ISO | Ankra2 (Mus musculus) | 6480464 | triptonide results in increased expression of ANKRA2 mRNA | CTD | PMID:33045310 | valproic acid | affects expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ANKRA2 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ANKRA2 mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | ANKRA2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ANKRA2 mRNA | CTD | PMID:27188386 | vincristine | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | Vincristine results in increased expression of ANKRA2 mRNA | CTD | PMID:23649840 | zoledronic acid | increases expression | ISO | ANKRA2 (Homo sapiens) | 6480464 | zoledronic acid results in increased expression of ANKRA2 mRNA | CTD | PMID:25596134 | |