C17h6orf62 (similar to human chromosome 6 open reading frame 62) - Rat Genome Database

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Gene: C17h6orf62 (similar to human chromosome 6 open reading frame 62) Rattus norvegicus
Analyze
Symbol: C17h6orf62 (Ensembl: C17h6orf62-ps1)
Name: similar to human chromosome 6 open reading frame 62 (Ensembl:similar to human chromosome 6 open reading frame 62, pseudogene 1)
RGD ID: 6491729
Description: Orthologous to human C6orf62 (chromosome 6 open reading frame 62); INTERACTS WITH bisphenol A; 2-hydroxypropanoic acid (ortholog); 5-azacytidine (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100911664; uncharacterized LOC100911664; uncharacterized protein C6orf62 homolog; uncharacterized protein LOC100911664
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: C17h6orf62-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81740,684,236 - 40,695,874 (-)NCBIGRCr8
mRatBN7.21740,256,211 - 40,267,851 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1740,256,211 - 40,276,020 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1740,324,398 - 40,336,037 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01741,928,443 - 41,940,082 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01740,211,495 - 40,223,115 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01742,256,971 - 42,268,607 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1742,257,019 - 42,276,797 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01744,124,742 - 44,136,371 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1739,893,497 - 39,905,141 (-)NCBICelera
Cytogenetic Map17p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
C17h6orf62
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81740,684,236 - 40,695,874 (-)NCBIGRCr8
mRatBN7.21740,256,211 - 40,267,851 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1740,256,211 - 40,276,020 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1740,324,398 - 40,336,037 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01741,928,443 - 41,940,082 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01740,211,495 - 40,223,115 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01742,256,971 - 42,268,607 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1742,257,019 - 42,276,797 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01744,124,742 - 44,136,371 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1739,893,497 - 39,905,141 (-)NCBICelera
Cytogenetic Map17p11NCBI
C6orf62
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38624,704,861 - 24,720,836 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl624,704,861 - 24,720,825 (-)EnsemblGRCh38hg38GRCh38
GRCh37624,705,089 - 24,721,064 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36624,813,137 - 24,827,382 (-)NCBINCBI36Build 36hg18NCBI36
Build 34624,813,144 - 24,827,382NCBI
Celera625,938,465 - 25,952,778 (-)NCBICelera
Cytogenetic Map6p22.3NCBI
HuRef624,654,519 - 24,668,831 (-)NCBIHuRef
CHM1_1624,709,233 - 24,723,547 (-)NCBICHM1_1
T2T-CHM13v2.0624,575,985 - 24,592,053 (-)NCBIT2T-CHM13v2.0
BC005537
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391324,985,640 - 24,996,882 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1324,985,640 - 25,000,180 (+)EnsemblGRCm39 Ensembl
GRCm381324,801,657 - 24,812,899 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1324,801,657 - 24,816,197 (+)EnsemblGRCm38mm10GRCm38
MGSCv371324,893,526 - 24,904,768 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361324,809,122 - 24,820,364 (+)NCBIMGSCv36mm8
Celera1325,032,322 - 25,043,564 (+)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map1310.68NCBI
LOC102009721
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554832,346,246 - 2,358,156 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554832,346,246 - 2,358,156 (+)NCBIChiLan1.0ChiLan1.0
C5H6orf62
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2539,355,474 - 39,372,837 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1635,355,011 - 35,372,360 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0624,543,074 - 24,559,096 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1624,874,941 - 24,891,081 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl624,875,047 - 24,891,081 (-)Ensemblpanpan1.1panPan2
C35H6orf62
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13522,725,186 - 22,741,526 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3522,726,357 - 22,741,119 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3522,692,529 - 22,708,852 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03522,847,340 - 22,863,737 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3522,846,861 - 22,864,328 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13522,652,800 - 22,669,174 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03522,700,379 - 22,716,750 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03524,136,690 - 24,153,084 (-)NCBIUU_Cfam_GSD_1.0
CUNH6orf62
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049462,644,372 - 2,655,961 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936671965,592 - 977,179 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936671965,598 - 977,181 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C7H6orf62
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl719,509,691 - 19,524,830 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1719,509,676 - 19,524,905 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2720,662,445 - 20,677,593 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CUNH6orf62
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11747,534,547 - 47,549,611 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1747,535,883 - 47,548,354 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604424,631,541 - 24,646,747 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH6orf62
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247562,335,958 - 2,347,944 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247562,335,394 - 2,349,823 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C17h6orf62
68 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172418489079524188Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
2313854Bp343Blood pressure QTL 3433.9life span trait (VT:0005372)age at time of death (CMO:0001193)173199078450909196Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172393042179524188Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2393042179524188Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172393042179524188Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat

Markers in Region
RH127745  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21740,256,256 - 40,256,461 (+)MAPPERmRatBN7.2
Rnor_6.01742,257,017 - 42,257,221NCBIRnor6.0
Rnor_5.01744,124,816 - 44,125,020UniSTSRnor5.0
RGSC_v3.41747,317,843 - 47,318,047UniSTSRGSC3.4
Celera1739,893,543 - 39,893,747UniSTS
Cytogenetic Map17p11UniSTS
RH140503  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21740,259,504 - 40,259,751 (+)MAPPERmRatBN7.2
Rnor_6.01742,260,263 - 42,260,509NCBIRnor6.0
Rnor_5.01744,128,062 - 44,128,308UniSTSRnor5.0
RGSC_v3.41747,321,090 - 47,321,336UniSTSRGSC3.4
Celera1739,896,790 - 39,897,036UniSTS
Cytogenetic Map17p11UniSTS
RH118352  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21740,259,415 - 40,259,585 (+)MAPPERmRatBN7.2
Rnor_6.01742,260,174 - 42,260,343NCBIRnor6.0
Rnor_5.01744,127,973 - 44,128,142UniSTSRnor5.0
RGSC_v3.41747,321,001 - 47,321,170UniSTSRGSC3.4
Celera1739,896,701 - 39,896,870UniSTS
Cytogenetic Map17p11UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000059564   ⟹   ENSRNOP00000056321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1740,256,211 - 40,267,603 (-)Ensembl
Rnor_6.0 Ensembl1742,257,019 - 42,267,079 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000083996   ⟹   ENSRNOP00000072694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1740,257,405 - 40,276,020 (-)Ensembl
Rnor_6.0 Ensembl1742,258,168 - 42,276,797 (-)Ensembl
RefSeq Acc Id: NM_001305277   ⟹   NP_001292206
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81740,684,236 - 40,695,874 (-)NCBI
mRatBN7.21740,256,211 - 40,267,851 (-)NCBI
Rnor_6.01742,256,971 - 42,268,607 (-)NCBI
Celera1739,893,497 - 39,905,141 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001292206 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH85940 (Get FASTA)   NCBI Sequence Viewer  
  AAH89212 (Get FASTA)   NCBI Sequence Viewer  
  AAP92627 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000056321.3
  ENSRNOP00000072694.1
RefSeq Acc Id: NP_001292206   ⟸   NM_001305277
- UniProtKB: Q7TP28 (UniProtKB/TrEMBL),   A0A0G2K3M0 (UniProtKB/TrEMBL),   F7ELW2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000056321   ⟸   ENSRNOT00000059564
Ensembl Acc Id: ENSRNOP00000072694   ⟸   ENSRNOT00000083996

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TP28-F1-model_v2 AlphaFold Q7TP28 1-229 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:6491729 AgrOrtholog
BioCyc Gene G2FUF-9421 BioCyc
Ensembl Genes ENSRNOG00000018456 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000059564.5 UniProtKB/TrEMBL
  ENSRNOT00000083996.2 UniProtKB/TrEMBL
InterPro DUF4566 UniProtKB/TrEMBL
KEGG Report rno:100911664 UniProtKB/TrEMBL
NCBI Gene LOC100911664 ENTREZGENE
PANTHER BA1-643 UniProtKB/TrEMBL
  PTHR28336 UniProtKB/TrEMBL
Pfam DUF4566 UniProtKB/TrEMBL
PhenoGen C17h6orf62 PhenoGen
RatGTEx ENSRNOG00000018456 RatGTEx
UniProt A0A0G2K3M0 ENTREZGENE, UniProtKB/TrEMBL
  F7ELW2 ENTREZGENE, UniProtKB/TrEMBL
  Q7TP28 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-12 C17h6orf62  similar to human chromosome 6 open reading frame 62  LOC100911664  uncharacterized LOC100911664  Name and Symbol changed 629549 APPROVED
2012-07-05 LOC100911664  uncharacterized LOC100911664      Symbol and Name status set to provisional 70820 PROVISIONAL