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Gene: Pafah2 (platelet-activating factor acetylhydrolase 2) Rattus norvegicus

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Symbol:

Pafah2

Name:

platelet-activating factor acetylhydrolase 2

RGD ID:

631399

Description:

Enables 1-alkyl-2-acetylglycerophosphocholine esterase activity and platelet-activating factor acetyltransferase activity. Involved in negative regulation of apoptotic process. Predicted to be located in cytoplasm. Orthologous to human PAFAH2 (platelet activating factor acetylhydrolase 2); PARTICIPATES IN ether lipid metabolic pathway; ether lipid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

PAF:lysophospholipid transacetylase; PAF:sphingosine transacetylase; platelet-activating factor acetylhydrolase 2 40kDa; platelet-activating factor acetylhydrolase 2, 40kDa; platelet-activating factor acetylhydrolase 2, cytoplasmic; platelet-activating factor acetyltransferase PAFAH2; SD-PLA2; serine-dependent phospholipase A2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	151,890,751 - 151,919,896 (+)	NCBI		GRCr8
mRatBN7.2	5	146,607,050 - 146,636,203 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	146,613,498 - 146,634,943 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	149,315,449 - 149,336,022 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	151,085,629 - 151,106,175 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	151,071,690 - 151,092,263 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	152,606,850 - 152,635,956 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	152,606,847 - 152,634,803 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	156,390,608 - 156,419,237 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	153,157,638 - 153,178,179 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	153,167,676 - 153,188,218 (+)	NCBI
Celera	5	145,029,049 - 145,049,591 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive hypercholesterolemia (ISO)

retinitis pigmentosa 59 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

8-epi-prostaglandin F2alpha (ISO)

acetamide (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

carbon nanotube (ISO)

choline (ISO)

clofibrate (ISO)

cocaine (EXP)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

epoxiconazole (ISO)

folic acid (ISO)

gentamycin (EXP)

indole-3-methanol (EXP)

inulin (ISO)

iron dichloride (ISO)

isotretinoin (ISO)

L-methionine (ISO)

methapyrilene (ISO)

methylmercury chloride (ISO)

N-methyl-N-nitrosourea (ISO)

N-nitrosodiethylamine (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

phosphatidylcholine (ISO)

pirinixic acid (ISO)

sodium fluoride (ISO)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

thiram (ISO)

triphenyl phosphate (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

lipid catabolic process (IEA)

negative regulation of apoptotic process (IMP)

Cellular Component

cytoplasm (ISS)

endoplasmic reticulum membrane (IEA)

mitochondrial membrane (IEA)

Molecular Function

1-alkyl-2-acetylglycerophosphocholine esterase activity (IBA,IDA,IEA,IMP,ISS)

platelet-activating factor acetyltransferase activity (IDA)

Molecular Pathway Annotations Click to see Annotation Detail View

ether lipid metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Anti-apoptotic actions of the platelet-activating factor acetylhydrolase I alpha2 catalytic subunit.	Bonin F, etal., J Biol Chem 2004 Dec 10;279(50):52425-36. Epub 2004 Sep 28.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Purification and characterization from rat kidney membranes of a novel platelet-activating factor (PAF)-dependent transacetylase that catalyzes the hydrolysis of PAF, formation of PAF analogs, and C2-ceramide.	Karasawa K, etal., J Biol Chem. 1999 Mar 26;274(13):8655-61. doi: 10.1074/jbc.274.13.8655.
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Pafah2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	151,890,751 - 151,919,896 (+)	NCBI		GRCr8
mRatBN7.2	5	146,607,050 - 146,636,203 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	146,613,498 - 146,634,943 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	149,315,449 - 149,336,022 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	151,085,629 - 151,106,175 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	151,071,690 - 151,092,263 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	152,606,850 - 152,635,956 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	152,606,847 - 152,634,803 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	156,390,608 - 156,419,237 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	153,157,638 - 153,178,179 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	153,167,676 - 153,188,218 (+)	NCBI
Celera	5	145,029,049 - 145,049,591 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

PAFAH2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	25,959,767 - 25,998,063 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	25,959,767 - 25,998,117 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	26,286,258 - 26,324,554 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	26,158,845 - 26,197,235 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	25,971,456 - 26,008,790	NCBI
Celera	1	24,682,324 - 24,720,714 (-)	NCBI		Celera
Cytogenetic Map	1	p36.11	NCBI
HuRef	1	24,540,816 - 24,578,700 (-)	NCBI		HuRef
CHM1_1	1	26,399,480 - 26,437,894 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	25,797,193 - 25,835,465 (-)	NCBI		T2T-CHM13v2.0

Pafah2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	134,123,631 - 134,154,723 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	134,123,631 - 134,154,724 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	134,396,320 - 134,427,412 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	134,396,320 - 134,427,413 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	133,952,275 - 133,983,327 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	133,669,545 - 133,699,484 (+)	NCBI		MGSCv36	mm8
Celera	4	132,570,680 - 132,602,137 (+)	NCBI		Celera
Cytogenetic Map	4	D2.3	NCBI
cM Map	4	66.68	NCBI

Pafah2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	5,440,341 - 5,475,105 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	5,440,766 - 5,474,483 (-)	NCBI	ChiLan1.0	ChiLan1.0

PAFAH2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	200,875,077 - 200,914,083 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	199,972,891 - 200,011,889 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	25,218,632 - 25,256,751 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	26,284,649 - 26,322,693 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	26,284,649 - 26,323,031 (-)	Ensembl	panpan1.1		panPan2

PAFAH2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	73,963,313 - 73,994,901 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	73,963,360 - 73,994,127 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	70,539,571 - 70,571,480 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	74,526,565 - 74,558,631 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	74,526,608 - 74,558,157 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	71,349,804 - 71,382,134 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	72,356,132 - 72,388,661 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	73,359,961 - 73,391,856 (+)	NCBI		UU_Cfam_GSD_1.0

Pafah2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	44,699,581 - 44,730,072 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	10,520,184 - 10,554,840 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	10,523,605 - 10,554,868 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PAFAH2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	83,411,553 - 83,446,834 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	83,413,513 - 83,446,967 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	77,049,137 - 77,082,468 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PAFAH2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	106,771,206 - 106,833,670 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	106,771,173 - 106,810,420 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	9,583,028 - 9,646,222 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pafah2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	10,044,174 - 10,069,157 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	10,045,509 - 10,076,996 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Pafah2
143 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	39
Count of miRNA genes:	37
Interacting mature miRNAs:	39
Transcripts:	ENSRNOT00000037097
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	97059760	147465714	Rat
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
2302369	Scl60	Serum cholesterol level QTL 60	3.13		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	143608201	161165651	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	135927956	166875058	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	135929696	166875058	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	144358090	157869054	Rat
70156	Niddm30	Non-insulin dependent diabetes mellitus QTL 30	3.98		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	5	129132447	151006154	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
631263	Cm24	Cardiac mass QTL 24	3.5		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	143799107	158428037	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	143069996	166846814	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	105999803	150999803	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
2293642	Bss37	Bone structure and strength QTL 37	4.64	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	120740824	151018848	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	103689353	148689353	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
2313096	Bmd78	Bone mineral density QTL 78	3.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	5	144377876	161317411	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	99216724	148607142	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_177932	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239127	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039110041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001837842	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC099104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY225592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000037097 ⟹ ENSRNOP00000034439

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	5	152,613,255 - 152,633,795 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000089070 ⟹ ENSRNOP00000068571

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	146,613,498 - 146,634,943 (+)	Ensembl
Rnor_6.0 Ensembl	5	152,606,847 - 152,634,803 (+)	Ensembl

RefSeq Acc Id:

NM_177932 ⟹ NP_808793

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	151,897,195 - 151,917,735 (+)	NCBI
mRatBN7.2	5	146,613,498 - 146,634,042 (+)	NCBI
Rnor_6.0	5	152,613,255 - 152,633,795 (+)	NCBI
Rnor_5.0	5	156,390,608 - 156,419,237 (+)	NCBI
RGSC_v3.4	5	153,157,638 - 153,178,179 (+)	RGD
Celera	5	145,029,049 - 145,049,591 (+)	RGD

Sequence:

show sequence

CAGCTGGTGATGAGATGGGGGCCGGTCAGTCTATATGCTTCCCGCCCATCTCCGGGCCCCACCA
CATTGGCTGCACGGATGTGATGGAGGGTCACAGTCTTGAGGGGAGCCTCTTCCGACTCTTCTAC
CCCTGCGAAGCATCAGAGACGTGCGAGCAGCCCCTGTGGATTCCCCGCTATGAGTACTGCGTGG
GTCTGGCTGACTACCTGCAGTATAACAAGCGCTGGGTGGGGCTGCTGTTCAACGTGGGCATCGG
ATCCTGTCGCTTGCCTGTTAGCTGGAACGGCCCCTTTAAGACAAAGGAATCTGGATACCCTTTG
ATCATCTTGTCCCATGGCCTAGGGGGCTTCAGGGTGTCATACTCGGCCTTCTGCATGGAGCTGG
CCTCCCGTGGCTTTGTGGTTGCTGCCATAGAGCACAGGGACCAGTCAGCTGCAGCCACCTACTT
CTGCAAGCAGACCTCCCAGGAGAGTTCGCCCACTGAGTCTCTGGAGGAGGAATGGATCCCCTTC
CGTCGGATCAAGGAAGGGGAGAAGGAATTCCATGTTAGGAATCCCCAGGTGCACCAGCGGGCGA
AAGAGTGTGTGCGCGTGCTGCAGATCCTTCAGGACGCCTCTGCTGGCAAGCCTGTCATCAATGT
CTTCCCAGGAGGACTGGATCTGATGACCTTGAAGGGCAGCATCGACATGAGCCGAGTGGCTGTG
ATGGGACACTCCTTCGGAGGGGCTACGGCTATTCTTGCTTTGACCCAGGAGGCCCAGTTTCGGT
GTGCTATAGCCCTGGACGCTTGGATGTTCCCTCTGGAACACGACTTCTACCCCAAGGCCCGGGG
CCCCGTGTTCTTTATAAACGTTGAGAAATTCCAGACAGTGGAGAGCGTGAACTTGATGAAGAAG
ATATGTGCCCAGCACGAGCAATCCAGGATCGTGACTGTCCTAGGCGCTGTTCATCGGAGTCAAA
CTGACTTTGCCTTTGTCACGGGCAACATGATTGGTAAACTCTTTTCCAGCGGCACACGTGGGAC
TTTGGACCCTTATGAAGGTCAGGAAGTCATGGTGCGGGCCATGTTGGCCTTCCTGCAGAAGCAC
CTCGACCTGAAGGAGGACTATGATCAGTGGAACAGCTTCATCGAAGGCATCGGACCGTCGCTCA
TCCAAGGGGCCCCACACTATCTGTCCAGCCTCTAGGTTG

hide sequence

RefSeq Acc Id:

XM_006239127 ⟹ XP_006239189

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	151,890,755 - 151,919,896 (+)	NCBI
mRatBN7.2	5	146,607,055 - 146,636,201 (+)	NCBI
Rnor_6.0	5	152,606,852 - 152,635,956 (+)	NCBI
Rnor_5.0	5	156,390,608 - 156,419,237 (+)	NCBI

Sequence:

show sequence

AGACACCAGGGGGCGCAATCTCACCTGGTCTTGGCTGATTTCACGCCGCCCCAGGGTGTAGTCA
GGAAACCTGGGAATTGTAGTCCTGGAAATGATAAGGCGCCGCGTTGTGTCCCGGGACTTGTAGT
GTACATTTAGAGACAGGGAACGAGTTTAAGTTCGCAGGTTAAGTGAAAGAACTAGTATTCCCAG
AGGCCCACGGGCTCCTGGGCGGTGCCGGGTTTCTGTGGAGTGACCCTTCTGAGGTTGCCTTTGA
ATGATCAGCGTGACTGGCCAGCAAGTTCCTGAGCACCCGCCTTTGGTTCAGCTGGTGATGAGAT
GGGGGCCGGTCAGTCTATATGCTTCCCGCCCATCTCCGGGCCCCACCACATTGGCTGCACGGAT
GTGATGGAGGGTCACAGTCTTGAGGGGAGCCTCTTCCGACTCTTCTACCCCTGCGAAGCATCAG
AGACGTGCGAGCAGCCCCTGTGGATTCCCCGCTATGAGTACTGCGTGGGTCTGGCTGACTACCT
GCAGTATAACAAGCGCTGGGTGGGGCTGCTGTTCAACGTGGGCATCGGATCCTGTCGCTTGCCT
GTTAGCTGGAACGGCCCCTTTAAGACAAAGGAATCTGGATACCCTTTGATCATCTTGTCCCATG
GCCTAGGGGGCTTCAGGGTGTCATACTCGGCCTTCTGCATGGAGCTGGCCTCCCGTGGCTTTGT
GGTTGCTGCCATAGAGCACAGGGACCAGTCAGCTGCAGCCACCTACTTCTGCAAGCAGACCTCC
CAGGAGAGTTCGCCCACTGAGTCTCTGGAGGAGGAATGGATCCCCTTCCGTCGGATCAAGGAAG
GGGAGAAGGAATTCCATGTTAGGAATCCCCAGGTGCACCAGCGGGCGAAAGAGTGTGTGCGCGT
GCTGCAGATCCTTCAGGACGCCTCTGCTGGCAAGCCTGTCATCAATGTCTTCCCAGGAGGACTG
GATCTGATGACCTTGAAGGGCAGCATCGACATGAGCCGAGTGGCTGTGATGGGACACTCCTTCG
GAGGGGCTACGGCTATTCTTGCTTTGACCCAGGAGGCCCAGTTTCGGTGTGCTATAGCCCTGGA
CGCTTGGATGTTCCCTCTGGAACACGACTTCTACCCCAAGGCCCGGGGCCCCGTGTTCTTTATA
AACGTTGAGAAATTCCAGACAGTGGAGAGCGTGAACTTGATGAAGAAGATATGTGCCCAGCACG
AGCAATCCAGGATCGTGACTGTCCTAGGCGCTGTTCATCGGAGTCAAACTGACTTTGCCTTTGT
CACGGGCAACATGATTGGTAAACTCTTTTCCAGCGGCACACGTGGGACTTTGGACCCTTATGAA
GGTCAGGAAGTCATGGTGCGGGCCATGTTGGCCTTCCTGCAGAAGCACCTCGACCTGAAGGAGG
ACTATGATCAGTGGAACAGCTTCATCGAAGGCATCGGACCGTCGCTCATCCAAGGGGCCCCACA
CTATCTGTCCAGCCTCTAGGTTGCTTGACCTGAGTTTTCACTTAGGAGCTGCCCAGGGATACTT
GCAACCTATTGGCAGGACCTTTCTCCCCAGAATGAGAAGATATATATATAATCAGAGCGCTGAC
TGGGCAACCGGATACTCTGCCCTTGGGATTGTTGATCTTAAATGCACCTCAGAACAGATTGTGG
ATGGTCGCTGGCTGATTGGGAAGCTGATTTTTTTTTTTTAAAGTCAAGGACTCGTGACCCAGAC
TGGCTCTGAACTTACTGCATAACGAGGATGGCCTTCTTTCTGAATGACAGACATTACCACCAGG
CCTGGCTGGTATTCAGTGCTGGGGATTGGAACTGATGCGAGTCACTGTGCTGGACTAGACTTAA
AGACTACGAAGTGCTTAGGTGCTGAGGCCCTGTTCTCGGTAGTCCCCACCTCTGTCCCGGGTTT
GCCTTAAGTAAGAACAGTGTTTATCTGCTCAGCCGAGTTCTCTCTTGGCTTGGGCCATTTCTAA
TATTCCAGCCATGCAATTTATCATGTGGAACCCTTACCACTAGGTGCCATTCCCTCTGTGCCAC
CATAACCCCACGGCCAGTCTTTTTGGCATCCCAGAGCACATCTCAAGGAAAACACACTGGCCCT
GTGGCACCTACTTTGGACTGACTTTACAGTGAAGGCTGGGCAGACCACTGTACTAACTGACCAC
ATCCCCCACTCTCGGCAAGCTAACTTTCTTAGGCTGAACTGAGAGACTCAGTCATAGGCTGAGA
CTGGCTGAACCCCCCCAAGCCCCAGGCGGAGCCCCATGGAGCCTGAATATGACAACTTGGCTGG
GCGAGCCCACTCTCTCACCTTGGGCAATTGTTGCTTCCTGAAGCCAAAGGCCTGACAGACACCT
TAGGGCTTCCAGCCCTGCCTGGTGCTCTCCACATGCCCTCTCTCTCTCTCTCCAGGGCAGTCTT
CTCACTGTGTGAAATATAGTAGTGGACACTTTTTTTACTGTCATGCTTAGAAGCCCATGTAGGG
CAGACAGTATTGTCCTCAAAACACAGACACCAAGAAGCCCCTCAGAGGCTCAGTGTCTTTGAGA
TCTCCCAAGTATTTCTTGTCAGGAAACATCCTGAGTGAGTTGAGATGGGCTTGAACTATTAACA
GAGCGGAGTTGCCATTTGCACAGACCTCAGAGGGCACCGGGTTGGCCAGCTCAAATCCAGGAAT
GTTCTAGAGAAGTCTGAGGGCAGCTTGGTCTTGCCTCTTATTCCAAACCAGGGTGCTTTAGTTG
TCTGTCTTGCTTTGTTTCTGGTTTTGTTTTTCCTTTTCCTTTTTTCTTTTTTTCTTTTCTTTTT
TTTTTTTTTTTTGAGGCTATCCCCCAATTTAAGTCAAGGAACAGATCCAGCCTGTTTCATCCTG
TTTCACTGAATAGTGATGCTCATGTTGGCCTTCGGGCTCGCTGTAATTTCATCTGTTTAATTGA
CATTAGAGCGAGTTGGAGAACCATCTGGAAGTCACTTTCCTGATTCTCTTTGTTTGCTAATCGT
GTGCCCTGTGGAAAATGAAATCTTCCCAGAGTTCCAAGTCCAGTGAGAAGGCTCACCTAGGACT
GTACCTCTGCCACACAAGAGAAGTCACCTGAGTCCAAGGAGGGAAGAACCCCGGAGAGGCAAGT
ACAGAATGGAGACGTATCCCTGCACAGTAGTCCAAGGTCAGGGCCAGCAAAGCAATCCAAAGGG
ACGCGCATACATCGGGAGGCTCCTCAGGCTCCGTTCCGCAGCTGCACGACTGGGCGTGGAGTTC
TGGCTTCACCACTGCATCGATCGGAGCAAATTCTGTTGTCTTCCCAACCTCCATTACGAATGGT
CGGAATGATCGAGTGAAGAGATGGATAATCCCCGGGTTCTTAAATGAGCGTTCCCCACGCCCCA
CACATGTGCTTTCTTTTTTCTTTTTTCTTTTTTTTTTTTTTTTTGGTTCTTTTTTTCCGGAGCT
GGGGACCGAACCCAGGGCCTTGCGCTTTCTAGGTAAGCGCTCTACCACTGAGCTAAATCCCCAG
CCCCACGCATGTGCTTTCTAATTGTATGTTCAATGTTTCCCGTCAGAAAGATCTGTATGATCGC
TACACTCCAAGATTTGTTGGAACGTGATTGTTCGCCCACTCACTGTATGATTAAAAAGTATTTT
TTTCTGAA

hide sequence

RefSeq Acc Id:

XM_017593404 ⟹ XP_017448893

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	151,890,755 - 151,919,896 (+)	NCBI
mRatBN7.2	5	146,607,054 - 146,636,201 (+)	NCBI
Rnor_6.0	5	152,606,851 - 152,635,956 (+)	NCBI

Sequence:

show sequence

CAGACACCAGGGGGCGCAATCTCACCTGGTCTTGGCTGATTTCACGCCGCCCCAGGGTGTAGTC
AGGAAACCTGGGAATTGTAGTCCTGGAAATGATAAGGCGCCGCGTTGTGTCCCGGGACTTGTAG
TGTACATTTAGAGACAGGGAACGAGTTTAAGTTCGCAGGTTAAGTGAAAGAACTAGTATTCCCA
GAGGCCCACGGGCTCCTGGGCGGTGCCGGGTTTCTGTGGAGTGACCCTTCTGAGGTTGCCTTTG
AATGATCAGCGTGACTGGGTTTTGAGGGATCTGAGGCTCATCACCACCGTCTCCTCACCCCACC
AGAAGGAAATGAAGACTACAGTGCTCGGGGCTGGGAATGGAGTGGGTCACTAGCATATGTAAGG
CTCCCAGCTTCCTTCCCACCACTGCAGAAAGACAACAGAAGGATCAGCCTGTAAACGGAAAGTA
GCAAACGTAAATAATGCGTGCGCTTCAGTGAGTAGCTGGCAGGAAGGTCAGTTGGGGTGATAAG
GATGTCAGGAAGTACACAGGGTTGGCACATGACCTAGAGAAACAACAAGCGAGGAAGAGACCAG
CAGGAGGCTGTTCTGCGCTCTGCCTTCCAGCCAGCAAGTTCCTGAGCACCCGCCTTTGGTTCAG
CTGGTGATGAGATGGGGGCCGGTCAGTCTATATGCTTCCCGCCCATCTCCGGGCCCCACCACAT
TGGCTGCACGGATGTGATGGAGGGTCACAGTCTTGAGGGGAGCCTCTTCCGACTCTTCTACCCC
TGCGAAGCATCAGAGACGTGCGAGCAGCCCCTGTGGATTCCCCGCTATGAGTACTGCGTGGGTC
TGGCTGACTACCTGCAGTATAACAAGCGCTGGGTGGGGCTGCTGTTCAACGTGGGCATCGGATC
CTGTCGCTTGCCTGTTAGCTGGAACGGCCCCTTTAAGACAAAGGAATCTGGATACCCTTTGATC
ATCTTGTCCCATGGCCTAGGGGGCTTCAGGGTGTCATACTCGGCCTTCTGCATGGAGCTGGCCT
CCCGTGGCTTTGTGGTTGCTGCCATAGAGCACAGGGACCAGTCAGCTGCAGCCACCTACTTCTG
CAAGCAGACCTCCCAGGAGAGTTCGCCCACTGAGTCTCTGGAGGAGGAATGGATCCCCTTCCGT
CGGATCAAGGAAGGGGAGAAGGAATTCCATGTTAGGAATCCCCAGGTGCACCAGCGGGCGAAAG
AGTGTGTGCGCGTGCTGCAGATCCTTCAGGACGCCTCTGCTGGCAAGCCTGTCATCAATGTCTT
CCCAGGAGGACTGGATCTGATGACCTTGAAGGGCAGCATCGACATGAGCCGAGTGGCTGTGATG
GGACACTCCTTCGGAGGGGCTACGGCTATTCTTGCTTTGACCCAGGAGGCCCAGTTTCGGTGTG
CTATAGCCCTGGACGCTTGGATGTTCCCTCTGGAACACGACTTCTACCCCAAGGCCCGGGGCCC
CGTGTTCTTTATAAACGTTGAGAAATTCCAGACAGTGGAGAGCGTGAACTTGATGAAGAAGATA
TGTGCCCAGCACGAGCAATCCAGGATCGTGACTGTCCTAGGCGCTGTTCATCGGAGTCAAACTG
ACTTTGCCTTTGTCACGGGCAACATGATTGGTAAACTCTTTTCCAGCGGCACACGTGGGACTTT
GGACCCTTATGAAGGTCAGGAAGTCATGGTGCGGGCCATGTTGGCCTTCCTGCAGAAGCACCTC
GACCTGAAGGAGGACTATGATCAGTGGAACAGCTTCATCGAAGGCATCGGACCGTCGCTCATCC
AAGGGGCCCCACACTATCTGTCCAGCCTCTAGGTTGCTTGACCTGAGTTTTCACTTAGGAGCTG
CCCAGGGATACTTGCAACCTATTGGCAGGACCTTTCTCCCCAGAATGAGAAGATATATATATAA
TCAGAGCGCTGACTGGGCAACCGGATACTCTGCCCTTGGGATTGTTGATCTTAAATGCACCTCA
GAACAGATTGTGGATGGTCGCTGGCTGATTGGGAAGCTGATTTTTTTTTTTTAAAGTCAAGGAC
TCGTGACCCAGACTGGCTCTGAACTTACTGCATAACGAGGATGGCCTTCTTTCTGAATGACAGA
CATTACCACCAGGCCTGGCTGGTATTCAGTGCTGGGGATTGGAACTGATGCGAGTCACTGTGCT
GGACTAGACTTAAAGACTACGAAGTGCTTAGGTGCTGAGGCCCTGTTCTCGGTAGTCCCCACCT
CTGTCCCGGGTTTGCCTTAAGTAAGAACAGTGTTTATCTGCTCAGCCGAGTTCTCTCTTGGCTT
GGGCCATTTCTAATATTCCAGCCATGCAATTTATCATGTGGAACCCTTACCACTAGGTGCCATT
CCCTCTGTGCCACCATAACCCCACGGCCAGTCTTTTTGGCATCCCAGAGCACATCTCAAGGAAA
ACACACTGGCCCTGTGGCACCTACTTTGGACTGACTTTACAGTGAAGGCTGGGCAGACCACTGT
ACTAACTGACCACATCCCCCACTCTCGGCAAGCTAACTTTCTTAGGCTGAACTGAGAGACTCAG
TCATAGGCTGAGACTGGCTGAACCCCCCCAAGCCCCAGGCGGAGCCCCATGGAGCCTGAATATG
ACAACTTGGCTGGGCGAGCCCACTCTCTCACCTTGGGCAATTGTTGCTTCCTGAAGCCAAAGGC
CTGACAGACACCTTAGGGCTTCCAGCCCTGCCTGGTGCTCTCCACATGCCCTCTCTCTCTCTCT
CCAGGGCAGTCTTCTCACTGTGTGAAATATAGTAGTGGACACTTTTTTTACTGTCATGCTTAGA
AGCCCATGTAGGGCAGACAGTATTGTCCTCAAAACACAGACACCAAGAAGCCCCTCAGAGGCTC
AGTGTCTTTGAGATCTCCCAAGTATTTCTTGTCAGGAAACATCCTGAGTGAGTTGAGATGGGCT
TGAACTATTAACAGAGCGGAGTTGCCATTTGCACAGACCTCAGAGGGCACCGGGTTGGCCAGCT
CAAATCCAGGAATGTTCTAGAGAAGTCTGAGGGCAGCTTGGTCTTGCCTCTTATTCCAAACCAG
GGTGCTTTAGTTGTCTGTCTTGCTTTGTTTCTGGTTTTGTTTTTCCTTTTCCTTTTTTCTTTTT
TTCTTTTCTTTTTTTTTTTTTTTTTGAGGCTATCCCCCAATTTAAGTCAAGGAACAGATCCAGC
CTGTTTCATCCTGTTTCACTGAATAGTGATGCTCATGTTGGCCTTCGGGCTCGCTGTAATTTCA
TCTGTTTAATTGACATTAGAGCGAGTTGGAGAACCATCTGGAAGTCACTTTCCTGATTCTCTTT
GTTTGCTAATCGTGTGCCCTGTGGAAAATGAAATCTTCCCAGAGTTCCAAGTCCAGTGAGAAGG
CTCACCTAGGACTGTACCTCTGCCACACAAGAGAAGTCACCTGAGTCCAAGGAGGGAAGAACCC
CGGAGAGGCAAGTACAGAATGGAGACGTATCCCTGCACAGTAGTCCAAGGTCAGGGCCAGCAAA
GCAATCCAAAGGGACGCGCATACATCGGGAGGCTCCTCAGGCTCCGTTCCGCAGCTGCACGACT
GGGCGTGGAGTTCTGGCTTCACCACTGCATCGATCGGAGCAAATTCTGTTGTCTTCCCAACCTC
CATTACGAATGGTCGGAATGATCGAGTGAAGAGATGGATAATCCCCGGGTTCTTAAATGAGCGT
TCCCCACGCCCCACACATGTGCTTTCTTTTTTCTTTTTTCTTTTTTTTTTTTTTTTTGGTTCTT
TTTTTCCGGAGCTGGGGACCGAACCCAGGGCCTTGCGCTTTCTAGGTAAGCGCTCTACCACTGA
GCTAAATCCCCAGCCCCACGCATGTGCTTTCTAATTGTATGTTCAATGTTTCCCGTCAGAAAGA
TCTGTATGATCGCTACACTCCAAGATTTGTTGGAACGTGATTGTTCGCCCACTCACTGTATGAT
TAAAAAGTATTTTTTTCTGAA

hide sequence

RefSeq Acc Id:

XM_039110041 ⟹ XP_038965969

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	151,890,755 - 151,919,896 (+)	NCBI
mRatBN7.2	5	146,607,054 - 146,636,201 (+)	NCBI

RefSeq Acc Id:

XR_001837842

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	151,890,751 - 151,917,772 (+)	NCBI
mRatBN7.2	5	146,607,050 - 146,636,203 (+)	NCBI
Rnor_6.0	5	152,606,850 - 152,633,785 (+)	NCBI

Sequence:

show sequence

TCAGACACCAGGGGGCGCAATCTCACCTGGTCTTGGCTGATTTCACGCCGCCCCAGGGTGTAGT
CAGGAAACCTGGGAATTGTAGTCCTGGAAATGATAAGGCGCCGCGTTGTGTCCCGGGACTTGTA
GTGTACATTTAGAGACAGGGAACGAGTTTAAGTTCGCAGGTTAAGTGAAAGAACTAGTATTCCC
AGAGGCCCACGGGCTCCTGGGCGGTGCCGGGTTTCTGTGGAGTGACCCTTCTGAGGTTGCCTTT
GAATGATCAGCGTGACTGGCCAGCAAGTTCCTGAGCACCCGCCTTTGGTTCAGCTGGTGATGAG
ATGGGGGCCGGTCAGTCTATATGCTTCCCGCCCATCTCCGGGCCCCACCACATTGGCTGCACGG
ATGTGATGGAGGGTCACAGTCTTGAGGGGAGCCTCTTCCGACTCTTCTACCCCTGCGAAGCATC
AGAGACGTGCGAGCAGCCCCTGTGGATTCCCCGCTATGAGTACTGCGTGGGTCTGGCTGACTAC
CTGCAGTATAACAAGCGCTGGGTGGGGCTGCTGTTCAACGTGGGCATCGGATCCTGTCGCTTGC
CTGTTAGCTGGAACGGCCCCTTTAAGACAAAGGAATCTGGATACCCTTTGATCATCTTGTCCCA
TGGCCTAGGGGGCTTCAGGGTGTCATACTCGGCCTTCTGCATGGAGCTGGCCTCCCGTGGCTTT
GTGGTTGCTGCCATAGAGCACAGGGACCAGTCAGCTGCAGCCACCTACTTCTGCAAGCAGACCT
CCCAGGAGAGTTCGCCCACTGAGTCTCTGGAGGAGGAATGGATCCCCTTCCGTCGGATCAAGGA
AGGGGAGAAGGAATTCCATGTTAGGAATCCCCAGGTGCACCAGCGGGCGAAAGAGTGTGTGCGC
GTGCTGCAGATCCTTCAGGACGCCTCTGCTGGCAAGCCTGTCATCAATGTCTTCCCAGGAGGAC
TGGATCTGATGACCTTGAAGGGCAGCATCGACATGAGCCGAGTGGCTGTGATGGGACACTCCTT
CGGAGGGGCTACGGCTATTCTTGCTTTGACCCAGGAGGCCCAGTTTCGGTGTGCTATAGCCCTG
GACGCTTGGATGTTCCCTCTGGAACACGACTTCTACCCCAAGGCCCGGGGCCCCGTGTTCTTTA
TAAACGTTGAGAAATTCCAGACAGTGGAGAGCGTGAACTTGATGAAGAAGATATGTGCCCAGCA
CGAGCAATCCAGGATCGTGACTGTCCTAGGCGCTGTTCATCGGAGTCAAACTGACTTTGCCTTT
GTCACGGGCAACATGATTGGTAAACTCTTTTCCAGCGGCACACGTGGGACTTTGGACCCTTATG
AAGGTCAGGAAGTCATGGTGCGGGCCATGTTGGCCTTCCTGCAGAAGCACCTCGCGTCTGTTTG
TTCACTCTCTGACTCCTCAGAACTTGGCTTAGCTCCTGCCACCGATGGCTGGTTCTCTCCTTGA
GGGTCCACGTCTTCCTCTCCAGAGCCCTCTCTTCACGATGTATTTGAGGGGACCTGAAGGAGGA
CTATGATCAGTGGAACAGCTTCATCGAAGGCATCGGACCGTCGCTCATCCAAGGGGCCCCACAC
TATCTGTCCAGC

hide sequence

Protein Sequences


Protein RefSeqs	NP_808793	(Get FASTA)	NCBI Sequence Viewer
	XP_006239189	(Get FASTA)	NCBI Sequence Viewer
	XP_017448893	(Get FASTA)	NCBI Sequence Viewer
	XP_038965969	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAO62314	(Get FASTA)	NCBI Sequence Viewer
	EDL80720	(Get FASTA)	NCBI Sequence Viewer
	EDL80721	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000068571.1
GenBank Protein	P83006	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_808793 ⟸ NM_177932

- UniProtKB:

Q80Z89 (UniProtKB/Swiss-Prot), P83006 (UniProtKB/Swiss-Prot), A6IT19 (UniProtKB/TrEMBL), A6IT20 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGAGQSICFPPISGPHHIGCTDVMEGHSLEGSLFRLFYPCEASETCEQPLWIPRYEYCVGLADY
LQYNKRWVGLLFNVGIGSCRLPVSWNGPFKTKESGYPLIILSHGLGGFRVSYSAFCMELASRGF
VVAAIEHRDQSAAATYFCKQTSQESSPTESLEEEWIPFRRIKEGEKEFHVRNPQVHQRAKECVR
VLQILQDASAGKPVINVFPGGLDLMTLKGSIDMSRVAVMGHSFGGATAILALTQEAQFRCAIAL
DAWMFPLEHDFYPKARGPVFFINVEKFQTVESVNLMKKICAQHEQSRIVTVLGAVHRSQTDFAF
VTGNMIGKLFSSGTRGTLDPYEGQEVMVRAMLAFLQKHLDLKEDYDQWNSFIEGIGPSLIQGAP
HYLSSL

hide sequence

RefSeq Acc Id:	XP_006239189 ⟸ XM_006239127
- Peptide Label:	isoform X1
- UniProtKB:	Q80Z89 (UniProtKB/Swiss-Prot), P83006 (UniProtKB/Swiss-Prot), A6IT19 (UniProtKB/TrEMBL), A6IT20 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGAGQSICFPPISGPHHIGCTDVMEGHSLEGSLFRLFYPCEASETCEQPLWIPRYEYCVGLADY LQYNKRWVGLLFNVGIGSCRLPVSWNGPFKTKESGYPLIILSHGLGGFRVSYSAFCMELASRGF VVAAIEHRDQSAAATYFCKQTSQESSPTESLEEEWIPFRRIKEGEKEFHVRNPQVHQRAKECVR VLQILQDASAGKPVINVFPGGLDLMTLKGSIDMSRVAVMGHSFGGATAILALTQEAQFRCAIAL DAWMFPLEHDFYPKARGPVFFINVEKFQTVESVNLMKKICAQHEQSRIVTVLGAVHRSQTDFAF VTGNMIGKLFSSGTRGTLDPYEGQEVMVRAMLAFLQKHLDLKEDYDQWNSFIEGIGPSLIQGAP HYLSSL hide sequence

RefSeq Acc Id:	XP_017448893 ⟸ XM_017593404
- Peptide Label:	isoform X1
- UniProtKB:	Q80Z89 (UniProtKB/Swiss-Prot), P83006 (UniProtKB/Swiss-Prot), A6IT19 (UniProtKB/TrEMBL), A6IT20 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGAGQSICFPPISGPHHIGCTDVMEGHSLEGSLFRLFYPCEASETCEQPLWIPRYEYCVGLADY LQYNKRWVGLLFNVGIGSCRLPVSWNGPFKTKESGYPLIILSHGLGGFRVSYSAFCMELASRGF VVAAIEHRDQSAAATYFCKQTSQESSPTESLEEEWIPFRRIKEGEKEFHVRNPQVHQRAKECVR VLQILQDASAGKPVINVFPGGLDLMTLKGSIDMSRVAVMGHSFGGATAILALTQEAQFRCAIAL DAWMFPLEHDFYPKARGPVFFINVEKFQTVESVNLMKKICAQHEQSRIVTVLGAVHRSQTDFAF VTGNMIGKLFSSGTRGTLDPYEGQEVMVRAMLAFLQKHLDLKEDYDQWNSFIEGIGPSLIQGAP HYLSSL hide sequence

Ensembl Acc Id:

ENSRNOP00000068571 ⟸ ENSRNOT00000089070

Ensembl Acc Id:

ENSRNOP00000034439 ⟸ ENSRNOT00000037097

RefSeq Acc Id:	XP_038965969 ⟸ XM_039110041
- Peptide Label:	isoform X1
- UniProtKB:	P83006 (UniProtKB/Swiss-Prot), Q80Z89 (UniProtKB/Swiss-Prot), A6IT19 (UniProtKB/TrEMBL), A6IT20 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P83006-F1-model_v2	AlphaFold	P83006	1-390	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694137

Promoter ID:

EPDNEW_R4662

Type:

multiple initiation site

Name:

Pafah2_1

Description:

platelet-activating factor acetylhydrolase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	152,607,100 - 152,607,160	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:631399	AgrOrtholog
BioCyc Gene	G2FUF-39573	BioCyc
Ensembl Genes	ENSRNOG00000022288	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000089070.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1820	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	AB_hydrolase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ac_Ohase_PAF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:313611	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	313611	ENTREZGENE
PANTHER	PAF_acetylhydro_II	UniProtKB/Swiss-Prot
	PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE 2, CYTOPLASMIC	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10272	UniProtKB/TrEMBL
Pfam	PAF-AH_p_II	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Pafah2	PhenoGen
PIRSF	PAF_acetylhydrolase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	LIPASE_SER	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000022288	RatGTEx
Superfamily-SCOP	SSF53474	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2JT51_RAT	UniProtKB/TrEMBL
	A6IT19	ENTREZGENE, UniProtKB/TrEMBL
	A6IT20	ENTREZGENE, UniProtKB/TrEMBL
	P83006	ENTREZGENE, UniProtKB/Swiss-Prot
	Q80Z89	ENTREZGENE
UniProt Secondary	Q80Z89	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-02-11	Slc1a7	platelet-activating factor acetylhydrolase 2	Pafah2	platelet-activating factor acetylhydrolase 2, 40kDa	Name updated to reflect Human and Mouse nomenclature	625702	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_product	one of three serine esterase isoenzymes that catalyze the inactivation of platelet-activating factor	1540381

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)