Exoc3 (exocyst complex component 3) - Rat Genome Database

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Gene: Exoc3 (exocyst complex component 3) Rattus norvegicus
Analyze
Symbol: Exoc3
Name: exocyst complex component 3
RGD ID: 621790
Description: Predicted to enable SNARE binding activity. Predicted to be involved in exocyst localization and exocytosis. Is active in presynaptic membrane. Orthologous to human EXOC3 (exocyst complex component 3); PARTICIPATES IN E-cadherin signaling pathway; insulin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: exocyst complex component Sec6; rSec6; Sec6; SEC6-like 1; SEC6-like 1 (S. cerevisiae); Sec6l1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,919,871 - 30,950,624 (+)NCBIGRCr8
mRatBN7.2129,091,298 - 29,122,056 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,091,294 - 29,122,045 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx128,893,113 - 28,923,914 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0134,892,975 - 34,923,773 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,093,734 - 29,124,536 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0131,700,953 - 31,731,726 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl131,700,953 - 31,731,815 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0133,126,575 - 33,159,109 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,897,536 - 29,928,281 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1129,902,027 - 29,931,141 (+)NCBI
Celera127,743,063 - 27,773,955 (+)NCBICelera
Cytogenetic Map1p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
allethrin  (EXP)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyhalothrin  (EXP)
cypermethrin  (EXP)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
diuron  (EXP)
elemental selenium  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
finasteride  (EXP)
flutamide  (EXP)
formaldehyde  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP,ISO)
indometacin  (ISO)
ivermectin  (ISO)
leflunomide  (EXP)
methyl methanesulfonate  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
ozone  (ISO)
phenylmercury acetate  (ISO)
piroxicam  (ISO)
potassium dichromate  (ISO)
pyrethrins  (EXP)
selenium atom  (ISO)
sodium arsenite  (ISO)
sulindac  (EXP)
tamibarotene  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
tungsten  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
protein binding  (IPI,ISO)
SNARE binding  (IBA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The glycine transporter GLYT1 interacts with Sec3, a component of the exocyst complex. Cubelos B, etal., Neuropharmacology. 2005 Nov;49(6):935-44. doi: 10.1016/j.neuropharm.2005.07.021. Epub 2005 Sep 21.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. MyRIP anchors protein kinase A to the exocyst complex. Goehring AS, etal., J Biol Chem. 2007 Nov 9;282(45):33155-67. Epub 2007 Sep 7.
4. GRIP1 and 2 regulate activity-dependent AMPA receptor recycling via exocyst complex interactions. Mao L, etal., Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19038-43. doi: 10.1073/pnas.1013494107. Epub 2010 Oct 18.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. rSec6 and rSec8, mammalian homologs of yeast proteins essential for secretion. Ting AE, etal., Proc Natl Acad Sci U S A 1995 Oct 10;92(21):9613-7.
11. Sec6 is localized to the plasma membrane of mature synaptic terminals and is transported with secretogranin II-containing vesicles. Vik-Mo EO, etal., Neuroscience. 2003;119(1):73-85.
Additional References at PubMed
PMID:11406615   PMID:12477932   PMID:15489334   PMID:25468996  


Genomics

Comparative Map Data
Exoc3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,919,871 - 30,950,624 (+)NCBIGRCr8
mRatBN7.2129,091,298 - 29,122,056 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,091,294 - 29,122,045 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx128,893,113 - 28,923,914 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0134,892,975 - 34,923,773 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,093,734 - 29,124,536 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0131,700,953 - 31,731,726 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl131,700,953 - 31,731,815 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0133,126,575 - 33,159,109 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,897,536 - 29,928,281 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1129,902,027 - 29,931,141 (+)NCBI
Celera127,743,063 - 27,773,955 (+)NCBICelera
Cytogenetic Map1p11NCBI
EXOC3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385443,176 - 467,290 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5443,175 - 471,937 (+)EnsemblGRCh38hg38GRCh38
GRCh375443,291 - 467,405 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365496,334 - 520,411 (+)NCBINCBI36Build 36hg18NCBI36
Build 345496,374 - 520,407NCBI
Celera5541,456 - 565,545 (+)NCBICelera
Cytogenetic Map5p15.33NCBI
HuRef5431,407 - 455,422 (+)NCBIHuRef
CHM1_15443,164 - 467,222 (+)NCBICHM1_1
T2T-CHM13v2.05438,418 - 462,555 (+)NCBIT2T-CHM13v2.0
Exoc3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391374,317,921 - 74,358,151 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1374,317,607 - 74,356,851 (-)EnsemblGRCm39 Ensembl
GRCm381374,169,802 - 74,210,032 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1374,169,488 - 74,208,732 (-)EnsemblGRCm38mm10GRCm38
MGSCv371374,307,253 - 74,346,148 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361374,635,807 - 74,674,702 (-)NCBIMGSCv36mm8
Celera1376,499,394 - 76,538,276 (-)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.15NCBI
Exoc3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955504196,695 - 223,812 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955504195,743 - 223,812 (+)NCBIChiLan1.0ChiLan1.0
EXOC3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24662,394 - 690,011 (+)NCBINHGRI_mPanPan1-v2
PanPan1.1 Ensembl5568,471 - 596,723 (+)Ensemblpanpan1.1panPan2
EXOC3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13411,790,927 - 11,811,566 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3411,791,926 - 11,811,561 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3416,304,626 - 16,325,902 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03411,695,749 - 11,716,848 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3411,694,759 - 11,716,578 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13411,746,203 - 11,767,708 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03411,727,053 - 11,748,335 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03411,937,421 - 11,958,497 (-)NCBIUU_Cfam_GSD_1.0
Exoc3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213244,844,352 - 244,861,748 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368151,005,560 - 1,023,070 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049368151,005,637 - 1,022,916 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXOC3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1679,705,750 - 79,730,047 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11679,705,743 - 79,730,272 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
EXOC3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.14320,067 - 359,647 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl4337,658 - 360,149 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606427,462,671 - 27,487,604 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Exoc3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624751215,821 - 255,104 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624751215,762 - 254,200 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Exoc3
248 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:116
Count of miRNA genes:86
Interacting mature miRNAs:92
Transcripts:ENSRNOT00000020251
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11620621049268520Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)11148148232355910Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1132356093Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)12076315844095856Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)11933357156983283Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1132356093Rat

Markers in Region
D1Got38  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2129,098,144 - 29,098,329 (+)MAPPERmRatBN7.2
Rnor_6.0131,707,798 - 31,707,982NCBIRnor6.0
Rnor_5.0133,133,228 - 33,133,412UniSTSRnor5.0
RGSC_v3.4129,904,378 - 29,904,563RGDRGSC3.4
RGSC_v3.4129,904,379 - 29,904,563UniSTSRGSC3.4
RGSC_v3.1129,907,323 - 29,907,508RGD
Celera127,749,908 - 27,750,092UniSTS
Cytogenetic Map1p11UniSTS
RH131026  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2129,121,898 - 29,122,081 (+)MAPPERmRatBN7.2
Rnor_6.0131,731,552 - 31,731,734NCBIRnor6.0
Rnor_5.0133,156,832 - 33,157,014UniSTSRnor5.0
RGSC_v3.4129,928,133 - 29,928,315UniSTSRGSC3.4
Celera127,773,807 - 27,773,989UniSTS
Cytogenetic Map1p11UniSTS
RH142744  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2129,103,267 - 29,103,539 (+)MAPPERmRatBN7.2
Rnor_6.0131,712,921 - 31,713,192NCBIRnor6.0
Rnor_5.0133,138,201 - 33,138,472UniSTSRnor5.0
RGSC_v3.4129,909,502 - 29,909,773UniSTSRGSC3.4
Celera127,755,181 - 27,755,452UniSTS
RH 3.4 Map1342.9UniSTS
Cytogenetic Map1p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000020251   ⟹   ENSRNOP00000020251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl129,091,298 - 29,122,045 (+)Ensembl
Rnor_6.0 Ensembl131,700,953 - 31,731,700 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077740   ⟹   ENSRNOP00000072705
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl129,091,294 - 29,122,045 (+)Ensembl
Rnor_6.0 Ensembl131,702,485 - 31,731,815 (+)Ensembl
RefSeq Acc Id: NM_001024964   ⟹   NP_001020135
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8130,919,875 - 30,950,622 (+)NCBI
mRatBN7.2129,091,298 - 29,122,047 (+)NCBI
Rnor_6.0131,700,953 - 31,731,700 (+)NCBI
Rnor_5.0133,126,575 - 33,159,109 (+)NCBI
RGSC_v3.4129,897,536 - 29,928,281 (+)RGD
Celera127,743,063 - 27,773,955 (+)RGD
Sequence:
RefSeq Acc Id: XM_006227767   ⟹   XP_006227829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8130,919,871 - 30,950,624 (+)NCBI
mRatBN7.2129,091,332 - 29,122,056 (+)NCBI
Rnor_6.0131,700,987 - 31,731,726 (+)NCBI
Rnor_5.0133,126,575 - 33,159,109 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006227768   ⟹   XP_006227830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8130,919,890 - 30,950,624 (+)NCBI
mRatBN7.2129,091,543 - 29,122,056 (+)NCBI
Rnor_6.0131,701,153 - 31,731,726 (+)NCBI
Rnor_5.0133,126,575 - 33,159,109 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001020135   ⟸   NM_001024964
- UniProtKB: Q4QQU2 (UniProtKB/Swiss-Prot),   Q62825 (UniProtKB/Swiss-Prot),   A6JUV0 (UniProtKB/TrEMBL),   A0A8L2QA79 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227829   ⟸   XM_006227767
- Peptide Label: isoform X1
- UniProtKB: Q4QQU2 (UniProtKB/Swiss-Prot),   Q62825 (UniProtKB/Swiss-Prot),   A6JUV0 (UniProtKB/TrEMBL),   A0A8L2QA79 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227830   ⟸   XM_006227768
- Peptide Label: isoform X1
- UniProtKB: Q4QQU2 (UniProtKB/Swiss-Prot),   Q62825 (UniProtKB/Swiss-Prot),   A6JUV0 (UniProtKB/TrEMBL),   A0A8L2QA79 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072705   ⟸   ENSRNOT00000077740
Ensembl Acc Id: ENSRNOP00000020251   ⟸   ENSRNOT00000020251

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62825-F1-model_v2 AlphaFold Q62825 1-755 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689557
Promoter ID:EPDNEW_R82
Type:multiple initiation site
Name:Exoc3_1
Description:exocyst complex component 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0131,700,938 - 31,700,998EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621790 AgrOrtholog
BioCyc Gene G2FUF-61940 BioCyc
Ensembl Genes ENSRNOG00000039776 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055003263 UniProtKB/Swiss-Prot
  ENSRNOG00060024786 UniProtKB/Swiss-Prot
  ENSRNOG00065019332 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000020251.6 UniProtKB/TrEMBL
  ENSRNOT00000077740.2 UniProtKB/Swiss-Prot
  ENSRNOT00055005065 UniProtKB/Swiss-Prot
  ENSRNOT00060042911 UniProtKB/Swiss-Prot
  ENSRNOT00065032525 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.357.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.357.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7446619 IMAGE-MGC_LOAD
InterPro EXOC3/Sec6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EXOC3/Sec6_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:252881 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:116137 IMAGE-MGC_LOAD
NCBI Gene 252881 ENTREZGENE
PANTHER EXOCYST COMPLEX COMPONENT 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR21292 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sec6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Exoc3 PhenoGen
RatGTEx ENSRNOG00000039776 RatGTEx
  ENSRNOG00055003263 RatGTEx
  ENSRNOG00060024786 RatGTEx
  ENSRNOG00065019332 RatGTEx
UniProt A0A8L2QA79 ENTREZGENE, UniProtKB/TrEMBL
  A6JUV0 ENTREZGENE, UniProtKB/TrEMBL
  A6JUV2_RAT UniProtKB/TrEMBL
  EXOC3_RAT UniProtKB/Swiss-Prot
  Q4QQU2 ENTREZGENE
  Q62825 ENTREZGENE
UniProt Secondary Q4QQU2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Exoc3  exocyst complex component 3  Sec6l1  SEC6-like 1 (S. cerevisiae)  Symbol and Name updated 1299863 APPROVED
2004-09-10 Sec6l1  SEC6-like 1 (S. cerevisiae)  Sec6  RSec6 protein  Symbol and Name updated 1299863 APPROVED
2002-08-07 Sec6  RSec6 protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology shows 22% amino acid identity to yeast Sec6p 633933
gene_protein 87-kDa protein 633933