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Gene: Tnni1 (troponin I1, slow skeletal type) Rattus norvegicus

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Symbol:

Tnni1

Name:

troponin I1, slow skeletal type

RGD ID:

621765

Description:

Predicted to enable actin binding activity. Predicted to be involved in cardiac muscle contraction and skeletal muscle contraction. Predicted to act upstream of or within transition between fast and slow fiber and ventricular cardiac muscle tissue morphogenesis. Part of troponin complex. Orthologous to human TNNI1 (troponin I1, slow skeletal type); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

troponin I skeletal slow 1; troponin I type 1 (skeletal, slow); troponin I, skeletal, slow 1; Troponin I, slow isoform; troponin I, slow skeletal muscle; troponin I, slow-twitch isoform

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TNNI1 (troponin I1, slow skeletal type)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Tnni1 (troponin I, skeletal, slow 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tnni1 (troponin I1, slow skeletal type)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TNNI1 (troponin I1, slow skeletal type)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TNNI1 (troponin I1, slow skeletal type)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tnni1 (troponin I1, slow skeletal type)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TNNI1 (troponin I1, slow skeletal type)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TNNI1 (troponin I1, slow skeletal type)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tnni1 (troponin I1, slow skeletal type)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	HPS4 (HPS4 biogenesis of lysosomal organelles complex 3 subunit 2)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	TNNI1 (troponin I1, slow skeletal type)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tnni1 (troponin I, skeletal, slow 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tnni1a (troponin I type 1a (skeletal, slow))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tnni1b (troponin I type 1b (skeletal, slow))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	tni-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	wupA	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	tni-3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	tni-4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	unc-27	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tnni1	Alliance	DIOPT (OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	49,781,529 - 49,793,385 (+)	NCBI		GRCr8
mRatBN7.2	13	47,229,217 - 47,241,640 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	47,229,216 - 47,241,644 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	49,837,958 - 49,848,647 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	51,126,025 - 51,136,714 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	48,389,874 - 48,400,620 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	52,624,856 - 52,637,297 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	52,624,878 - 52,637,297 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	57,672,816 - 57,685,255 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	48,830,442 - 48,841,258 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	48,844,484 - 48,855,301 (+)	NCBI
Celera	13	47,546,945 - 47,557,674 (+)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

familial adult myoclonic epilepsy 5 (ISO)

gastrointestinal stromal tumor (ISO)

Hypokalemic Periodic Paralysis, Type 1 (ISO)

parathyroid carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

4,4'-sulfonyldiphenol (ISO)

5-fluorouracil (EXP)

aflatoxin B1 (ISO)

alpha-Zearalanol (EXP)

aluminium phosphide (EXP)

ammonium chloride (EXP)

Azoxymethane (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bosentan (EXP)

CGP 52608 (ISO)

dextran sulfate (ISO)

doxorubicin (EXP,ISO)

flavonoids (EXP)

graphite (EXP)

methamphetamine (EXP)

methylmercury chloride (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

N-methyl-4-phenylpyridinium (ISO)

nitrofen (EXP)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (EXP)

perfluorooctanoic acid (EXP)

pirinixic acid (ISO)

proanthocyanidin (EXP)

resveratrol (ISO)

sodium arsenite (EXP)

spermine (ISO)

sunitinib (ISO)

tebuconazole (ISO)

titanium dioxide (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cardiac muscle contraction (IBA)

skeletal muscle contraction (IBA)

transition between fast and slow fiber (IEA,ISO)

ventricular cardiac muscle tissue morphogenesis (IEA,ISO)

Cellular Component

troponin complex (IBA,IDA,IEA)

Molecular Function

actin binding (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

acebutolol pharmacodynamics pathway (ISO)

adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway (ISO)

amiodarone pharmacodynamics pathway (ISO)

amlodipine pharmacodynamics pathway (ISO)

atenolol pharmacodynamics pathway (ISO)

betaxolol pharmacodynamics pathway (ISO)

bisoprolol pharmacodynamics pathway (ISO)

bupranolol drug pathway (ISO)

bupranolol pharmacodynamics pathway (ISO)

carvedilol pharmacodynamics pathway (ISO)

diltiazem pharmacodynamics pathway (ISO)

disopyramide pharmacodynamics pathway (ISO)

dobutamine pharmacodynamics pathway (ISO)

esmolol pharmacodynamics pathway (ISO)

flecainde pharmacodynamics pathway (ISO)

fosphenytoin pharmacodynamics pathway (ISO)

ibutilide pharmacodynamics pathway (ISO)

isoprenaline pharmacodynamics pathway (ISO)

isradipine pharmacodynamics pathway (ISO)

levobunolol pharmacodynamics pathway (ISO)

lidocaine pharmacodynamics pathway (ISO)

metoprolol pharmacodynamics pathway (ISO)

mexiletine pharmacodynamics pathway (ISO)

nadolol pharmacodynamics pathway (ISO)

nebivolol pharmacodynamics pathway (ISO)

nifedipine pharmacodynamics pathway (ISO)

nimodipine pharmacodynamics pathway (ISO)

nisoldipine pharmacodynamics pathway (ISO)

nitrendipine pharmacodynamics pathway (ISO)

penbutolol pharmacodynamics pathway (ISO)

phenytoin pharmacodynamics pathway (ISO)

pindolol pharmacodynamics pathway (ISO)

procainamide pharmacodynamics pathway (ISO)

propranolol pharmacodynamics pathway (ISO)

quinidine pharmacodynamics pathway (ISO)

sotalol pharmacodynamics pathway (ISO)

timolol pharmacodynamics pathway (ISO)

verapamil pharmacodynamics pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Coupled expression of troponin T and troponin I isoforms in single skeletal muscle fibers correlates with contractility.	Brotto MA, etal., Am J Physiol Cell Physiol. 2006 Feb;290(2):C567-76. Epub 2005 Sep 28.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	cDNA clone and expression analysis of rodent fast and slow skeletal muscle troponin I mRNAs.	Koppe RI, etal., J Biol Chem 1989 Aug 25;264(24):14327-33.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
8.	GOA pipeline	RGD automated data pipeline
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9915769	PMID:12551900	PMID:12815045	PMID:14726477	PMID:15601779	PMID:16679402	PMID:17602701	PMID:18423659	PMID:18550549	PMID:18850076	PMID:18978355	PMID:19184367
PMID:19507043	PMID:26391394	PMID:28864299	PMID:30820991	PMID:31505169	PMID:31981571	PMID:35352799

Genomics

Comparative Map Data

Tnni1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	49,781,529 - 49,793,385 (+)	NCBI		GRCr8
mRatBN7.2	13	47,229,217 - 47,241,640 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	47,229,216 - 47,241,644 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	49,837,958 - 49,848,647 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	51,126,025 - 51,136,714 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	48,389,874 - 48,400,620 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	52,624,856 - 52,637,297 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	52,624,878 - 52,637,297 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	57,672,816 - 57,685,255 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	48,830,442 - 48,841,258 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	48,844,484 - 48,855,301 (+)	NCBI
Celera	13	47,546,945 - 47,557,674 (+)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

TNNI1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	201,403,784 - 201,421,730 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	201,403,784 - 201,429,866 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	201,372,912 - 201,390,858 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	199,639,518 - 199,657,497 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	198,104,552 - 198,122,531	NCBI
Celera	1	174,496,762 - 174,514,748 (-)	NCBI		Celera
Cytogenetic Map	1	q32.1	NCBI
HuRef	1	172,538,919 - 172,556,905 (-)	NCBI		HuRef
CHM1_1	1	202,795,059 - 202,813,037 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	200,661,585 - 200,679,520 (-)	NCBI		T2T-CHM13v2.0

Tnni1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	135,709,252 - 135,738,727 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	135,707,172 - 135,738,727 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	135,783,033 - 135,810,989 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	135,779,434 - 135,810,989 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	137,695,998 - 137,707,566 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	137,616,244 - 137,627,387 (+)	NCBI		MGSCv36	mm8
Celera	1	138,433,849 - 138,445,388 (+)	NCBI		Celera
Cytogenetic Map	1	E4	NCBI
cM Map	1	59.28	NCBI

Tnni1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	37,534,453 - 37,554,868 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	37,535,397 - 37,554,868 (-)	NCBI	ChiLan1.0	ChiLan1.0

TNNI1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	47,962,860 - 47,974,464 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	47,924,558 - 47,937,485 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	177,006,262 - 177,054,525 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	181,308,154 - 181,329,486 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	181,309,609 - 181,314,889 (-)	Ensembl	panpan1.1		panPan2

TNNI1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	1,647,138 - 1,658,648 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	1,647,377 - 1,658,724 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	1,521,941 - 1,533,380 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	1,478,422 - 1,490,139 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	1,482,036 - 1,489,861 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	1,466,030 - 1,477,462 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	1,545,747 - 1,585,433 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	1,598,424 - 1,609,860 (+)	NCBI		UU_Cfam_GSD_1.0

Tnni1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	73,761,666 - 73,790,461 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936567	3,013,342 - 3,025,171 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936567	3,013,359 - 3,025,137 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TNNI1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	23,788,279 - 23,804,119 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	23,788,279 - 23,800,554 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	28,197,736 - 28,209,608 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TNNI1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	27,989,743 - 28,009,234 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	27,997,709 - 28,002,646 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	28,788,564 - 28,801,513 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tnni1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624807	9,294,951 - 9,308,446 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624807	9,295,121 - 9,306,368 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tnni1
108 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	44
Count of miRNA genes:	39
Interacting mature miRNAs:	43
Transcripts:	ENSRNOT00000012095
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	46088046	91088046	Rat
10755495	Bp387	Blood pressure QTL 387	3.78		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	34663461	87525369	Rat
9589141	Insul28	Insulin level QTL 28	10.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	13	9313465	54313465	Rat
6893344	Cm79	Cardiac mass QTL 79	1.5	0.04	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	43720770	62022792	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	37374509	82374509	Rat
71119	Thym2	Thymus enlargement QTL 2	3.8		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	13	46197976	84753113	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	22301875	67301875	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	37415584	80753406	Rat
2317040	Aia21	Adjuvant induced arthritis QTL 21	2.75		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	9831541	54831541	Rat
631645	Bp121	Blood pressure QTL 121	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	14915655	59915655	Rat
2317046	Aia8	Adjuvant induced arthritis QTL 8	3.9700000286102295		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	9831541	54831541	Rat
12879441	Bp396	Blood pressure QTL 396			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45699983	90699983	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	39754544	84754544	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	8897350	101631289	Rat
70170	Eae14	Experimental allergic encephalomyelitis QTL 14		0.0024	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	23203448	68203448	Rat
1331784	Bp222	Blood pressure QTL 222	2.944		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	17694436	53050594	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	34535218	79535218	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	5994833	77046787	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	38433408	83433408	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	20605871	101339738	Rat
4145117	Mcs27	Mammary carcinoma susceptibility QTL 27		0.0001	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	13	43437904	47841255	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	23692969	68692969	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	31241331	93395974	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	37374509	82374509	Rat
2303563	Bw89	Body weight QTL 89	6		body mass (VT:0001259)	body weight (CMO:0000012)	13	32284471	77284471	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	30395351	101056920	Rat
2301962	Cm72	Cardiac mass QTL 72	4.12		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	13	31241331	58363171	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	5994833	77046787	Rat
12879477	Bp401	Blood pressure QTL 401			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	37262092	82262092	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	37415584	82415584	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	23692969	68692969	Rat
12879472	Bp399	Blood pressure QTL 399			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45228358	47841255	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	101056920	Rat
9589164	Gluco66	Glucose level QTL 66	6.67	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	13	15158722	60158722	Rat
7411662	Foco29	Food consumption QTL 29	20.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	13	9313465	54313465	Rat

Markers in Region

D13Wox16

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	47,227,783 - 47,228,023 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	52,623,446 - 52,623,685	NCBI	Rnor6.0
Rnor_5.0	13	57,671,404 - 57,671,643	UniSTS	Rnor5.0
RGSC_v3.4	13	48,828,447 - 48,828,686	UniSTS	RGSC3.4
Celera	13	47,544,962 - 47,545,189	UniSTS
Cytogenetic Map	13	q13	UniSTS

RH133325

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	47,240,297 - 47,241,401 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	52,635,956 - 52,637,059	NCBI	Rnor6.0
Rnor_5.0	13	57,683,914 - 57,685,017	UniSTS	Rnor5.0
RGSC_v3.4	13	48,840,957 - 48,842,060	UniSTS	RGSC3.4
Celera	13	47,557,373 - 47,558,476	UniSTS
RH 3.4 Map	13	128.2	UniSTS
Cytogenetic Map	13	q13	UniSTS

RH142414

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	47,241,382 - 47,241,591 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	52,637,041 - 52,637,249	NCBI	Rnor6.0
Rnor_5.0	13	57,684,999 - 57,685,207	UniSTS	Rnor5.0
RGSC_v3.4	13	48,842,042 - 48,842,250	UniSTS	RGSC3.4
Celera	13	47,558,458 - 47,558,666	UniSTS
Cytogenetic Map	13	q13	UniSTS

RH137504

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	47,241,386 - 47,241,612 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	52,637,045 - 52,637,270	NCBI	Rnor6.0
Rnor_5.0	13	57,685,003 - 57,685,228	UniSTS	Rnor5.0
RGSC_v3.4	13	48,842,046 - 48,842,271	UniSTS	RGSC3.4
Celera	13	47,558,462 - 47,558,687	UniSTS
Cytogenetic Map	13	q13	UniSTS

TNNI1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	47,239,328 - 47,240,318 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	52,634,987 - 52,635,976	NCBI	Rnor6.0
Rnor_5.0	13	57,682,945 - 57,683,934	UniSTS	Rnor5.0
RGSC_v3.4	13	48,839,988 - 48,840,977	UniSTS	RGSC3.4
Celera	13	47,556,404 - 47,557,393	UniSTS
Cytogenetic Map	13	q13	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	66	70	70	40	25	40	6	197	95	48	45	60	30

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_017184	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249868	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598771	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC096932	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214889	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215520	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215566	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ216822	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217390	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217411	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	J04993	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000012095 ⟹ ENSRNOP00000012096

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	47,233,038 - 47,241,644 (+)	Ensembl
Rnor_6.0 Ensembl	13	52,625,441 - 52,636,257 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076054 ⟹ ENSRNOP00000067933

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	47,229,216 - 47,241,623 (+)	Ensembl
Rnor_6.0 Ensembl	13	52,624,878 - 52,637,297 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076299 ⟹ ENSRNOP00000068337

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	47,236,001 - 47,241,644 (+)	Ensembl
Rnor_6.0 Ensembl	13	52,624,905 - 52,636,258 (+)	Ensembl

RefSeq Acc Id:

NM_017184 ⟹ NP_058880

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	49,781,529 - 49,792,345 (+)	NCBI
mRatBN7.2	13	47,229,779 - 47,240,599 (+)	NCBI
Rnor_6.0	13	52,625,441 - 52,636,257 (+)	NCBI
Rnor_5.0	13	57,672,816 - 57,685,255 (+)	NCBI
RGSC_v3.4	13	48,830,442 - 48,841,258 (+)	RGD
Celera	13	47,546,945 - 47,557,674 (+)	RGD

Sequence:

show sequence

TCTCATCTGCACAGGAACCAACAGGTGCTGCCTTGTTACCACCATGCCGGAAGTTGAGAGGAAA
TCTAAGATCACTGCCTCCCGTAAACTCATGCTGAAGAGCCTGATGCTAGCCAAGGCCAAGGAGT
GCTGGGAGCAGGAGCACGAGGAGCGAGAGGCTGAGAAGGTGCGTTACCTCTCGGAGCGCATCCC
TACGCTGCAGACCCGCGGTCTTTCCCTCAGCGCCCTTCAGGACTTATGCCGAGAGCTCCATGCC
AAGGTGGAGGTGGTGGATGAGGAGCGCTATGATATCGAAGCCAAATGCCTCCACAACACGAGAG
AGATCAAGGACCTGAAGCTGAAGGTGCTGGACCTCCGTGGGAAGTTCAAGCGTCCACCCCTGCG
CCGGGTCCGTGTCTCAGCCGACGCCATGCTCCGAGCCCTACTGGGTTCCAAACACAAGGTGTCC
ATGGATCTGCGGGCCAACCTCAAGTCTGTGAAGAAAGAAGACACAGAAAAGGAGCGGCCAGTGG
AGGTGGGAGACTGGAGGAAGAACGTGGAGGCCATGTCTGGCATGGAAGGTCGCAAGAAGATGTT
CGATGCTGCCAAGTCCCCAACCTTGCAGTAGAGGTGCTTAGAGTGCTCTTCTTGGTGCCCCTCA
GAATCCTGGGGCACTCAGGAGAAGGGATGGGAGGCTGACCCAACGTACAGAACTCTTAGGAGTC
AGCTCTCTTGGGTTCAAGCCTACTGCAGTGTCTTCAGACACTGGGCACAGCATGCCTGTGTCAG
GTCTTTTTTTGCTGTTGTTGTTCCCTCATCAATAAAACTTGGGCTTGTATGTG

hide sequence

RefSeq Acc Id:

XM_006249862 ⟹ XP_006249924

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	49,786,905 - 49,793,385 (+)	NCBI
mRatBN7.2	13	47,235,158 - 47,241,640 (+)	NCBI
Rnor_6.0	13	52,629,428 - 52,637,297 (+)	NCBI
Rnor_5.0	13	57,672,816 - 57,685,255 (+)	NCBI

Sequence:

show sequence

CTGCGCTGCTTAGTTCTTCTAACTGTTGAAGATGGGGTGGACCTGAGGGGAAGATGGAGATAGG
GTCAAAGCCAAGATAGGATGGGGATGCCAGTGACGGAGAAAACTCCCAGGAGAAGAGAAGCAAA
GACCAAAGCTGTCATGTGCTTGGATGCAGGGCTCCGGGATGCCCCTCACAGGTCTTCATGTTCT
CCCCTGGGCCTTCCTCAAGCTCCTGCATCCCCGGGGGCTTCATTCTACCTCTTGCAAAGCTGTT
GTCATTTGAAAAGCTTTATGGCTGAACACTGAGGAAGGAATGCAGGTGTGTCCTTAGGTTCCCC
TCAGGATCATGGCCACCCTCACTCTGGACACTGTCTAATCCAAATTTCAGGCCGCAGAGAAGAC
AGCCTGCATGTAGTCCAGGGGTGAGGGCTGAAGGAAAACTGGTGTGCTGACTCAAATGGAGAGG
TGATGTCACTGACAGAGGGGACACTTGGCCTGGCTAGTCTGAGCGAGAGGCAAATATAGCATTT
CCTCATGACCGTATGAGCCCTTCAGTTTTGGTGAGGCTCCTATCTGAGTGAAACCCTGGGAACC
ATTGTTTAGATGAAGAGTCAGCGAGTGGTGGGAGAACGACACTGCAAAAGGCCATTCCCCCAGG
GAGTATCTGGGAGGGTGAACCAGGTGCTGTCATGGCCCCAGCAACCGGCTGTTTCTCTCATTAC
CTGGAGCGTAAGCTTTCGAAGATAAAAAGATAAGCCCCCGGTGAGTAGATCGGGAGTCATACTC
TGTGTGCTAAAGCTCACTCATTGCCTTTCCCCTCACTGCCACAGAGCCCTGTCATGTCTGCCTG
ACATACTGAGGAGCAGACCCTAGCTGTGCTCTCCCAGGGCAGATAACACCTGAGATAGCCAGGC
TGCTCAATGGGACAGCAAAGAGGAAACCCAGGAGAGACACAAGGGCTCCAAGCCTCCTAAGCCT
AAGTCAGCAGTAAGGTGTCTCTGTCACCTTCACCATGCTGGGGGACACTGTCACAAGGCTGGAC
TTTGAAACATTTTTTAGATAGGTTCTTCCATATAGTCTATGATTTTCCATGATGGCCCTCGACA
TGTGAGCCTCCTGTCTTAGCTTCCGGACTGCTGAGGTTGCACATATGATCCACCATGCCTGGCC
TTGGAGGAGACTTACTAGGAGTTACCAAAACATACCTATTTGGTCGTCAAGAATTTGCCTGCTC
CTTTTGGCTGGAATATCCCCCAGCAATGTTTTTGTATCCTAGAGATTGGTGTGGATGAAGGTAA
CTCGTAAAGTAGTTCTGACGTCCACACAGACACACTTCCCTTCTCTGGGACACATACAGCATGT
ATCTCTGGCAGGAAGGAACACCCAGATAGAGCTGCGTTATCACCCGGGGTGCTAAAACATATGC
CTGTTTTGGGCTTTTCACGAAGGCTGCACATCTGTGCCCTCATTTGGTCCCGCTGGAGCTGTGG
ACTAACCACAGTTGTCAGCGTGCTCCTCCGCAGATGCAGAAGGTACCTGTGGGAGGACATCTGC
AGTTTCCCGAGGGATCCTTCCAGCAGTGAAAGGAAATCTAAGATCACTGCCTCCCGTAAACTCA
TGCTGAAGAGCCTGATGCTAGCCAAGGCCAAGGAGTGCTGGGAGCAGGAGCACGAGGAGCGAGA
GGCTGAGAAGGTGCGTTACCTCTCGGAGCGCATCCCTACGCTGCAGACCCGCGGTCTTTCCCTC
AGCGCCCTTCAGGACTTATGCCGAGAGCTCCATGCCAAGGTGGAGGTGGTGGATGAGGAGCGCT
ATGATATCGAAGCCAAATGCCTCCACAACACGAGAGAGATCAAGGACCTGAAGCTGAAGGTGCT
GGACCTCCGTGGGAAGTTCAAGCGTCCACCCCTGCGCCGGGTCCGTGTCTCAGCCGACGCCATG
CTCCGAGCCCTACTGGGTTCCAAACACAAGGTGTCCATGGATCTGCGGGCCAACCTCAAGTCTG
TGAAGAAAGAAGACACAGAAAAGGAGCGGCCAGTGGAGGTGGGAGACTGGAGGAAGAACGTGGA
GGCCATGTCTGGCATGGAAGGCCGCAAGAAGATGTTCGATGCTGCCAAGTCCCCAACCTCGCAG
TAGAGGTCGGCTTGCTGAATGGCACTCTGGGTCACGCTTTGGTCCCCTTCCAGCCCCACTCACC
TATCCTTCTGCCCATGCCTGGAGCCCTTCCTCCCTCCAGCTCTACTATGCCCACCTTTGAAGCC
AGGATGAGTGCACACAGAGGGGAAGAGAGACGCTGGTGCCTGAGACCTCATTCCGGCAGTGTGG
GCTTACAGTACCCACCGGGCATGCTGGGGTTATCCAGACACCCCAAGGGGCCCTAGGCTGAGGA
GGGAGGCAGAGAGAATGCCTTCGCAGCAGCCCCATATTGCTTCCCTCCACTTCTGTTGCTATCT
GCAGTGTTCCCAAGTTCTCCATTAAAAAAATCCAGGGTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_058880	(Get FASTA)	NCBI Sequence Viewer
	XP_006249924	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA42295	(Get FASTA)	NCBI Sequence Viewer
	EDM09682	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000012096.7
	ENSRNOP00000067933.2
	ENSRNOP00000068337.2
GenBank Protein	P13413	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_058880 ⟸ NM_017184
- UniProtKB:	P13413 (UniProtKB/Swiss-Prot), F1LMC6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPEVERKSKITASRKLMLKSLMLAKAKECWEQEHEEREAEKVRYLSERIPTLQTRGLSLSALQD LCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALL GSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTLQ hide sequence

RefSeq Acc Id:

XP_006249924 ⟸ XM_006249862

- Peptide Label:

isoform X1

- Sequence:

show sequence

MPVLGFSRRLHICALIWSRWSCGLTTVVSVLLRRCRRYLWEDICSFPRDPSSSERKSKITASRK
LMLKSLMLAKAKECWEQEHEEREAEKVRYLSERIPTLQTRGLSLSALQDLCRELHAKVEVVDEE
RYDIEAKCLHNTREIKDLKLKVLDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLK
SVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ

hide sequence

Ensembl Acc Id:

ENSRNOP00000012096 ⟸ ENSRNOT00000012095

Ensembl Acc Id:

ENSRNOP00000068337 ⟸ ENSRNOT00000076299

Ensembl Acc Id:

ENSRNOP00000067933 ⟸ ENSRNOT00000076054

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P13413-F1-model_v2	AlphaFold	P13413	1-187	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698851

Promoter ID:

EPDNEW_R9372

Type:

initiation region

Name:

Tnni1_1

Description:

troponin I1, slow skeletal type

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	52,624,905 - 52,624,965	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621765	AgrOrtholog
BioCyc Gene	G2FUF-18191	BioCyc
Ensembl Genes	ENSRNOG00000009073	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000012095.9	UniProtKB/TrEMBL
	ENSRNOT00000076054.3	UniProtKB/TrEMBL
	ENSRNOT00000076299.3	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.350	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	6.10.250.180	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Troponin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Troponin_I	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Troponin_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:29388	UniProtKB/Swiss-Prot
NCBI Gene	29388	ENTREZGENE
PANTHER	TROPONIN I	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TROPONIN I, SLOW SKELETAL MUSCLE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Troponin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Tnni1	PhenoGen
RatGTEx	ENSRNOG00000009073	RatGTEx
Superfamily-SCOP	SSF90250	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A096MIZ5_RAT	UniProtKB/TrEMBL
	A0A096MK09_RAT	UniProtKB/TrEMBL
	A6ICG5_RAT	UniProtKB/TrEMBL
	F1LMC6	ENTREZGENE, UniProtKB/TrEMBL
	P13413	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-24	Tnni1	troponin I1, slow skeletal type	Tnni1	troponin I type 1 (skeletal, slow)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-10-23	Tnni1	troponin I type 1 (skeletal, slow)	Tnni1	troponin I, skeletal, slow 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-12-14	Tnni1	troponin I, skeletal, slow 1		Troponin I, slow isoform	Name updated	1299863	APPROVED
2002-08-07	Tnni1				Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	different isoforms are expressed in the various classes of vertebrate striated muscle cells	729969

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Annotations - SMPDB