Imported Disease Annotations - ClinVarObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Adgrl3 | Rat | Neurodevelopmental Disorders | | ISO | ADGRL3 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Neurodevelopmental disorder | ClinVar | PMID:25741868 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Imported Disease Annotations - CTD
Imported Disease Annotations - MGI
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Involvement of the calcium-independent receptor for alpha-latrotoxin in brain ischemia. | Bin Sun H, etal., Brain Res Mol Brain Res. 2002 Aug 15;104(2):246-9. |
| 2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 3. | A novel ubiquitously expressed alpha-latrotoxin receptor is a member of the CIRL family of G-protein-coupled receptors. | Ichtchenko K, etal., J Biol Chem 1999 Feb 26;274(9):5491-8. |
| 4. | The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins. | Kreienkamp HJ, etal., J Biol Chem. 2000 Oct 20;275(42):32387-90. |
| 5. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
| 6. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 7. | Knockout of latrophilin-3 in Sprague-Dawley rats causes hyperactivity, hyper-reactivity, under-response to amphetamine, and disrupted dopamine markers. | Regan SL, etal., Neurobiol Dis. 2019 Oct;130:104494. doi: 10.1016/j.nbd.2019.104494. Epub 2019 Jun 6. |
| 8. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 9. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 10. | Comprehensive gene review and curation | RGD comprehensive gene curation |
Additional References at PubMed
| PMID:9830014 | PMID:22405201 | PMID:22575564 | PMID:24613359 | PMID:24739570 | PMID:25728924 | PMID:25931508 | PMID:26235030 | PMID:26235031 | PMID:32203648 | PMID:34352385 | PMID:35985692 |
Genomics
Comparative Map Data
| Adgrl3 (Rattus norvegicus - Norway rat) |
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| ADGRL3 (Homo sapiens - human) |
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| Adgrl3 (Mus musculus - house mouse) |
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| Adgrl3 (Chinchilla lanigera - long-tailed chinchilla) |
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| ADGRL3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| ADGRL3 (Canis lupus familiaris - dog) |
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| Adgrl3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| ADGRL3 (Sus scrofa - pig) |
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| ADGRL3 (Chlorocebus sabaeus - green monkey) |
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| Adgrl3 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Adgrl3
5747 total Variants 
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