(+)-taxifolin multiple interactions ISO XDH (Homo sapiens) 6480464 taxifolin inhibits the reaction [XDH protein results in increased chemical synthesis of Superoxides] CTD PMID:19555678 (+)-taxifolin multiple interactions EXP 6480464 taxifolin inhibits the reaction [Rotenone results in increased activity of XDH protein] CTD PMID:35187747 (R)-adrenaline multiple interactions EXP 6480464 [Epinephrine co-treated with Xanthine co-treated with XDH] affects the expression of MYL2 protein more ... CTD PMID:19135123 and PMID:19464573 (R)-lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [Valproic Acid results in increased activity of XDH protein] CTD PMID:32662911 (S)-naringenin multiple interactions EXP 6480464 naringenin inhibits the reaction [Benzo(a)pyrene results in increased activity of XDH protein] CTD PMID:27206700 (S)-nicotine increases activity EXP 6480464 Nicotine results in increased activity of XDH protein CTD PMID:31857090 (S)-nicotine multiple interactions EXP 6480464 Sodium Acetate inhibits the reaction [Nicotine results in increased activity of XDH protein] CTD PMID:31857090 1,1-dichloroethene increases expression ISO Xdh (Mus musculus) 6480464 vinylidene chloride results in increased expression of XDH mRNA CTD PMID:26682919 1,2-dichloroethane decreases expression ISO Xdh (Mus musculus) 6480464 ethylene dichloride results in decreased expression of XDH mRNA CTD PMID:28960355 1,2-dimethylhydrazine affects expression ISO Xdh (Mus musculus) 6480464 1 and 2-Dimethylhydrazine affects the expression of XDH mRNA CTD PMID:22206623 1,4-dithiothreitol multiple interactions EXP 6480464 Dithiothreitol inhibits the reaction [chloramine affects the activity of XDH protein] CTD PMID:19527742 1-methyl-7H-xanthine increases metabolic processing ISO XDH (Homo sapiens) 6480464 XDH protein alternative form results in increased metabolism of 1-methylxanthine CTD PMID:19215233 1-methyl-7H-xanthine multiple interactions ISO XDH (Homo sapiens) 6480464 [XDH protein alternative form results in increased metabolism of 1-methylxanthine] which results in increased chemical synthesis of 1-methyluric acid CTD PMID:19215233 1-methyluric acid multiple interactions ISO XDH (Homo sapiens) 6480464 [XDH protein alternative form results in increased metabolism of 1-methylxanthine] which results in increased chemical synthesis of 1-methyluric acid CTD PMID:19215233 1-naphthyl isothiocyanate multiple interactions ISO Xdh (Mus musculus) 6480464 [1-Naphthylisothiocyanate co-treated with Allopurinol] results in increased expression of XDH mRNA and [1-Naphthylisothiocyanate co-treated with Uric Acid] results in increased expression of XDH mRNA CTD PMID:33749747 1-naphthyl isothiocyanate increases expression ISO Xdh (Mus musculus) 6480464 1-Naphthylisothiocyanate results in increased expression of XDH mRNA CTD PMID:33749747 11-deoxycorticosterone increases activity EXP 6480464 Desoxycorticosterone results in increased activity of XDH protein CTD PMID:16271043 11-deoxycorticosterone multiple interactions EXP 6480464 Desoxycorticosterone promotes the reaction [XDH protein results in increased chemical synthesis of Reactive Oxygen Species] CTD PMID:16271043 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of XDH mRNA CTD PMID:15834898 and PMID:17557909 17beta-estradiol increases expression ISO Xdh (Mus musculus) 6480464 Estradiol results in increased expression of XDH mRNA CTD PMID:15289156 and PMID:19484750 17beta-estradiol multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of XDH mRNA CTD PMID:32741896 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of XDH mRNA CTD PMID:32145629 17beta-estradiol multiple interactions ISO XDH (Homo sapiens) 6480464 [Estradiol co-treated with Progesterone] results in increased expression of XDH mRNA and [Estradiol co-treated with TGFB1 protein] results in increased expression of XDH mRNA CTD PMID:20660070 and PMID:30165855 17beta-estradiol 3-benzoate multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of XDH mRNA CTD PMID:32741896 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO XDH (Homo sapiens) 6480464 [Tetrachlorodibenzodioxin co-treated with Mitomycin co-treated with Oxygen deficiency] affects the activity of XDH protein and [Tetrachlorodibenzodioxin co-treated with Oxygen deficiency] results in decreased activity of XDH protein CTD PMID:16226770 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of XDH mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Xdh (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of XDH mRNA CTD PMID:16962184 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Xdh (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of XDH mRNA CTD PMID:15251184 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO XDH (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of XDH mRNA CTD PMID:23152189 2,3,7,8-tetrachlorodibenzodioxine increases activity ISO Xdh (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased activity of XDH protein CTD PMID:11243847 and PMID:21846477 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of XDH mRNA CTD PMID:22298810 and PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of XDH mRNA CTD PMID:16054898 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Xdh (Mus musculus) 6480464 [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of XDH mRNA more ... CTD PMID:11243847 more ... 2,3,7,8-tetrachlorodibenzodioxine increases activity ISO XDH (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased activity of XDH protein CTD PMID:16226770 2,4-diaminotoluene increases expression ISO Xdh (Mus musculus) 6480464 2 and 4-diaminotoluene results in increased expression of XDH mRNA CTD PMID:20713471 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of XDH mRNA CTD PMID:21346803 2-acetamidofluorene increases activity EXP 6480464 2-Acetylaminofluorene results in increased activity of XDH protein CTD PMID:23665045 2-acetamidofluorene multiple interactions EXP 6480464 Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of XDH protein] CTD PMID:23665045 2-amino-2-deoxy-D-galactopyranose increases activity EXP 6480464 Galactosamine results in increased activity of XDH protein CTD PMID:35673974 2-amino-2-deoxy-D-galactopyranose multiple interactions EXP 6480464 Vitamin U inhibits the reaction [Galactosamine results in increased activity of XDH protein] CTD PMID:35673974 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased abundance of Proteoglycans] and [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA] CTD PMID:11801247 2-hydroxypropanoic acid decreases expression ISO XDH (Homo sapiens) 6480464 Lactic Acid results in decreased expression of XDH mRNA CTD PMID:30851411 2-nitroanisole increases reduction ISO XDH (Homo sapiens) 6480464 XDH protein results in increased reduction of 2-nitroanisole CTD PMID:14729594 2-nitrofluorene decreases expression EXP 6480464 2-nitrofluorene results in decreased expression of XDH mRNA CTD PMID:15890375 2-nitrofluorene increases reduction ISO Xdh (Mus musculus) 6480464 XDH protein results in increased reduction of 2-nitrofluorene CTD PMID:15932950 2-nitrofluorene increases reduction EXP 6480464 XDH protein results in increased reduction of 2-nitrofluorene CTD PMID:15932950 3',5'-cyclic GMP multiple interactions EXP 6480464 [Xanthine co-treated with XDH protein] inhibits the reaction [Nitroprusside results in increased abundance of Cyclic GMP] CTD PMID:17339839 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine increases activity EXP 6480464 Puromycin Aminonucleoside results in increased activity of XDH CTD PMID:11041286 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions EXP 6480464 [Tungsten co-treated with Puromycin Aminonucleoside] results in decreased activity of XDH protein CTD PMID:7583048 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Xdh (Mus musculus) 6480464 3 more ... CTD PMID:23994337 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:34256052 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP 6480464 AHR gene mutant form inhibits the reaction [3 more ... CTD PMID:34256052 3,7-dihydropurine-6-thione increases expression EXP 6480464 Mercaptopurine results in increased expression of XDH mRNA CTD PMID:22688000 3,7-dihydropurine-6-thione affects expression EXP 6480464 Mercaptopurine affects the expression of XDH mRNA CTD PMID:23358152 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Xdh (Mus musculus) 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of XDH mRNA more ... CTD PMID:16054899 3-methylcholanthrene multiple interactions ISO Xdh (Mus musculus) 6480464 AHR protein promotes the reaction [Methylcholanthrene results in increased activity of XDH protein] CTD PMID:11243847 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of XDH mRNA CTD PMID:23273579 3-methylcholanthrene increases expression ISO Xdh (Mus musculus) 6480464 Methylcholanthrene results in increased expression of XDH mRNA CTD PMID:20713471 and PMID:29554273 3-methylcholanthrene increases activity ISO Xdh (Mus musculus) 6480464 Methylcholanthrene results in increased activity of XDH protein CTD PMID:11243847 3-phenylprop-2-enal multiple interactions EXP 6480464 cinnamaldehyde inhibits the reaction [Testosterone results in increased activity of XDH protein modified form] CTD PMID:32628957 4'-epidoxorubicin increases activity EXP 6480464 Epirubicin results in increased activity of XDH protein CTD PMID:36822302 4'-epidoxorubicin multiple interactions EXP 6480464 3-(indol-3-yl)propionic acid inhibits the reaction [Epirubicin results in increased activity of XDH protein] CTD PMID:36822302 4,4'-sulfonyldiphenol affects methylation ISO Xdh (Mus musculus) 6480464 bisphenol S affects the methylation of XDH gene CTD PMID:31683443 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one decreases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of XDH mRNA CTD PMID:15890375 4-hydroxynon-2-enal increases expression ISO Xdh (Mus musculus) 6480464 4-hydroxy-2-nonenal results in increased expression of XDH mRNA CTD PMID:19191707 4-hydroxyphenyl retinamide decreases expression ISO Xdh (Mus musculus) 6480464 Fenretinide results in decreased expression of XDH mRNA CTD PMID:28973697 5-azaorotic acid multiple interactions ISO Xdh (Mus musculus) 6480464 [Oxonic Acid analog co-treated with Hypoxanthine] results in increased activity of XDH protein more ... CTD PMID:34687833 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of XDH mRNA CTD PMID:24780913 and PMID:30047161 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of XDH mRNA CTD PMID:25825206 7,12-dimethyltetraphene decreases expression EXP 6480464 9 more ... CTD PMID:12376462 7,12-dimethyltetraphene increases expression ISO Xdh (Mus musculus) 6480464 9 more ... CTD PMID:32553695 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO XDH (Homo sapiens) 6480464 Fructose promotes the reaction [XDH protein results in increased chemical synthesis of Uric Acid] CTD PMID:19158351 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases chemical synthesis ISO Xdh (Mus musculus) 6480464 XDH protein results in increased chemical synthesis of Uric Acid CTD PMID:22036979 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO Xdh (Mus musculus) 6480464 [1-Naphthylisothiocyanate co-treated with Uric Acid] results in increased expression of XDH mRNA more ... CTD PMID:22036979 more ... 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions EXP 6480464 [2 more ... CTD PMID:21920950 and PMID:37601897 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases chemical synthesis ISO XDH (Homo sapiens) 6480464 XDH protein results in increased chemical synthesis of Uric Acid CTD PMID:19158351 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases abundance EXP 6480464 XDH protein results in increased abundance of Uric Acid CTD PMID:17439425 7H-xanthine multiple interactions EXP 6480464 3 more ... CTD PMID:12595275 more ... 7H-xanthine multiple interactions ISO Xdh (Mus musculus) 6480464 [Xanthine co-treated with XDH protein] results in increased expression of SOD2 protein CTD PMID:22718889 7H-xanthine multiple interactions ISO XDH (Homo sapiens) 6480464 [[Xanthine co-treated with XDH protein] results in increased abundance of Superoxides] which results in increased secretion of TGFB1 protein more ... CTD PMID:12531891 more ... 9H-xanthine multiple interactions EXP 6480464 3 more ... CTD PMID:12595275 more ... 9H-xanthine multiple interactions ISO Xdh (Mus musculus) 6480464 [Xanthine co-treated with XDH protein] results in increased expression of SOD2 protein CTD PMID:22718889 9H-xanthine multiple interactions ISO XDH (Homo sapiens) 6480464 [[Xanthine co-treated with XDH protein] results in increased abundance of Superoxides] which results in increased secretion of TGFB1 protein more ... CTD PMID:12531891 more ... acetaldehyde increases expression ISO XDH (Homo sapiens) 6480464 Acetaldehyde results in increased expression of XDH mRNA and Acetaldehyde results in increased expression of XDH protein CTD PMID:18845238 acetaldehyde multiple interactions ISO XDH (Homo sapiens) 6480464 [MPO protein co-treated with XDH protein co-treated with Acetaldehyde co-treated with Serotonin] affects the metabolism of and binds to GAPDH protein and [MPO protein co-treated with XDH protein co-treated with Acetaldehyde] promotes the reaction [Serotonin binds to Acetylcysteine] CTD PMID:23009681 acetic acid increases activity ISO Xdh (Mus musculus) 6480464 Acetic Acid results in increased activity of XDH protein CTD PMID:3677084 aflatoxin B1 affects expression ISO XDH (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of XDH protein CTD PMID:20106945 aflatoxin B1 decreases methylation ISO XDH (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of XDH gene CTD PMID:27153756 aflatoxin B1 decreases expression ISO XDH (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of XDH mRNA CTD PMID:27153756 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of XDH mRNA CTD PMID:15890375 Aflatoxin B2 alpha increases methylation ISO XDH (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of XDH exon CTD PMID:30157460 aldehydo-D-glucosamine multiple interactions EXP 6480464 [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased abundance of Proteoglycans] and [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA] CTD PMID:11801247 aldehydo-D-glucose multiple interactions EXP 6480464 [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucose results in increased abundance of Proteoglycans] and [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucose results in increased expression of B3GAT3 mRNA] CTD PMID:11801247 all-trans-retinoic acid multiple interactions ISO Xdh (Mus musculus) 6480464 Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein] CTD PMID:3677084 allantoin multiple interactions EXP 6480464 [2 more ... CTD PMID:21920950 allopurinol multiple interactions EXP 6480464 Allopurinol inhibits the reaction [[Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide] more ... CTD PMID:12566098 more ... allopurinol decreases activity ISO Xdh (Mus musculus) 6480464 Allopurinol results in decreased activity of XDH protein CTD PMID:20142047 and PMID:3677084 allopurinol decreases activity EXP 6480464 Allopurinol results in decreased activity of XDH protein CTD PMID:12694877 more ... allopurinol affects activity EXP 6480464 Allopurinol affects the activity of XDH protein CTD PMID:12115777 allopurinol multiple interactions ISO Xdh (Mus musculus) 6480464 [1-Naphthylisothiocyanate co-treated with Allopurinol] results in increased expression of XDH mRNA more ... CTD PMID:33749747 more ... allopurinol decreases activity ISO XDH (Homo sapiens) 6480464 Allopurinol results in decreased activity of XDH protein CTD PMID:19933411 alloxan multiple interactions EXP 6480464 Taurine inhibits the reaction [Alloxan results in increased activity of XDH protein] CTD PMID:22138235 alloxan increases activity EXP 6480464 Alloxan results in increased activity of XDH protein CTD PMID:22138235 alloxanthine decreases activity EXP 6480464 Oxypurinol results in decreased activity of XDH protein CTD PMID:26968635 aluminium atom increases activity EXP 6480464 Aluminum results in increased activity of XDH protein CTD PMID:11787993 aluminium(0) increases activity EXP 6480464 Aluminum results in increased activity of XDH protein CTD PMID:11787993 amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of XDH mRNA CTD PMID:30047161 ammonium acetate affects activity EXP 6480464 ammonium acetate affects the activity of XDH protein CTD PMID:12885441 ammonium acetate multiple interactions EXP 6480464 Dizocilpine Maleate inhibits the reaction [ammonium acetate affects the activity of XDH protein] CTD PMID:12885441 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of XDH mRNA CTD PMID:16483693 anthocyanin multiple interactions EXP 6480464 Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased activity of XDH protein] CTD PMID:30825423 apocynin multiple interactions EXP 6480464 acetovanillone inhibits the reaction [Cocaine results in increased activity of XDH protein] CTD PMID:17217956 aristolochic acid A increases expression ISO XDH (Homo sapiens) 6480464 aristolochic acid I results in increased expression of XDH mRNA CTD PMID:33212167 Aroclor 1254 decreases expression ISO Xdh (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of XDH mRNA CTD PMID:23650126 arsane affects methylation ISO XDH (Homo sapiens) 6480464 Arsenic affects the methylation of XDH gene CTD PMID:25304211 arsane multiple interactions ISO XDH (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of XDH mRNA CTD PMID:32525701 arsenic atom multiple interactions ISO XDH (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of XDH mRNA CTD PMID:32525701 arsenic atom affects methylation ISO XDH (Homo sapiens) 6480464 Arsenic affects the methylation of XDH gene CTD PMID:25304211 arsenite(3-) multiple interactions ISO XDH (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to XDH mRNA] CTD PMID:32406909 aspartame multiple interactions ISO Xdh (Mus musculus) 6480464 [Fats and Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of XDH mRNA CTD PMID:23783067 avobenzone increases expression ISO XDH (Homo sapiens) 6480464 avobenzone results in increased expression of XDH mRNA CTD PMID:31016361 baicalein multiple interactions ISO Xdh (Mus musculus) 6480464 baicalein inhibits the reaction [[Biological Products co-treated with potassium oxonate] results in increased activity of XDH protein] CTD PMID:34044073 baicalin multiple interactions ISO Xdh (Mus musculus) 6480464 baicalin inhibits the reaction [[Biological Products co-treated with potassium oxonate] results in increased activity of XDH protein] CTD PMID:34044073 Benoxacor increases expression ISO Xdh (Mus musculus) 6480464 benoxacor results in increased expression of XDH mRNA CTD PMID:34850242 benzo[a]pyrene increases expression ISO Xdh (Mus musculus) 6480464 Benzo(a)pyrene metabolite results in increased expression of XDH mRNA more ... CTD PMID:19770486 more ... benzo[a]pyrene increases activity EXP 6480464 Benzo(a)pyrene results in increased activity of XDH protein CTD PMID:27206700 benzo[a]pyrene multiple interactions EXP 6480464 naringenin inhibits the reaction [Benzo(a)pyrene results in increased activity of XDH protein] CTD PMID:27206700 benzo[a]pyrene decreases expression ISO XDH (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of XDH mRNA CTD PMID:32234424 benzo[a]pyrene affects methylation ISO XDH (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of XDH exon and Benzo(a)pyrene affects the methylation of XDH promoter CTD PMID:27901495 and PMID:30157460 benzo[a]pyrene increases activity ISO Xdh (Mus musculus) 6480464 Benzo(a)pyrene results in increased activity of XDH protein CTD PMID:28032951 and PMID:29019276 benzo[a]pyrene multiple interactions ISO Xdh (Mus musculus) 6480464 carvacrol inhibits the reaction [Benzo(a)pyrene results in increased activity of XDH protein] more ... CTD PMID:28032951 more ... benzo[a]pyrene affects expression ISO Xdh (Mus musculus) 6480464 Benzo(a)pyrene affects the expression of XDH mRNA CTD PMID:22342234 Benzoyl peroxide affects activity ISO Xdh (Mus musculus) 6480464 Benzoyl Peroxide affects the activity of XDH protein CTD PMID:15248479 Benzoyl peroxide multiple interactions ISO Xdh (Mus musculus) 6480464 cycloartenol inhibits the reaction [Benzoyl Peroxide results in increased activity of XDH protein] more ... CTD PMID:12804013 more ... Benzoyl peroxide increases activity ISO Xdh (Mus musculus) 6480464 Benzoyl Peroxide results in increased activity of XDH protein CTD PMID:12804013 more ... beta-D-glucosamine multiple interactions EXP 6480464 [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased abundance of Proteoglycans] and [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA] CTD PMID:11801247 beta-naphthoflavone increases expression ISO Xdh (Mus musculus) 6480464 beta-Naphthoflavone results in increased expression of XDH mRNA CTD PMID:23994337 bezafibrate decreases activity EXP 6480464 Bezafibrate results in decreased activity of XDH protein CTD PMID:8373410 bezafibrate multiple interactions EXP 6480464 Bezafibrate results in increased degradation of and results in decreased expression of XDH mRNA CTD PMID:8373410 bezafibrate decreases expression EXP 6480464 Bezafibrate results in decreased expression of XDH protein CTD PMID:8373410 bis(2-ethylhexyl) phthalate decreases activity EXP 6480464 Diethylhexyl Phthalate results in decreased activity of XDH protein CTD PMID:8373410 bisphenol A increases expression ISO Xdh (Mus musculus) 6480464 bisphenol A results in increased expression of XDH mRNA CTD PMID:26063408 and PMID:32156529 bisphenol A multiple interactions ISO Xdh (Mus musculus) 6480464 [bisphenol A results in increased activity of XDH protein] which results in increased chemical synthesis of Uric Acid CTD PMID:31574244 bisphenol A increases activity ISO Xdh (Mus musculus) 6480464 bisphenol A results in increased activity of XDH protein CTD PMID:31574244 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of XDH mRNA and bisphenol A results in decreased expression of XDH protein CTD PMID:24552547 more ... bisphenol F increases activity EXP 6480464 bisphenol F results in increased activity of XDH protein CTD PMID:37601897 bisphenol F multiple interactions EXP 6480464 [bisphenol F results in increased activity of XDH protein] which results in increased abundance of Uric Acid CTD PMID:37601897 bosentan decreases expression ISO XDH (Homo sapiens) 6480464 Bosentan results in decreased expression of XDH mRNA CTD PMID:29761207 buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of XDH mRNA CTD PMID:24136188 butanal increases expression ISO XDH (Homo sapiens) 6480464 butyraldehyde results in increased expression of XDH mRNA CTD PMID:26079696 C60 fullerene increases expression EXP 6480464 fullerene C60 results in increased expression of XDH mRNA CTD PMID:19167457 cadmium dichloride increases expression ISO XDH (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of XDH mRNA CTD PMID:25882684 caffeine affects metabolic processing ISO XDH (Homo sapiens) 6480464 XDH protein affects the metabolism of Caffeine CTD PMID:14586384 more ... carbon monoxide increases activity EXP 6480464 Carbon Monoxide results in increased activity of XDH protein CTD PMID:1447108 carbon monoxide increases metabolic processing EXP 6480464 Carbon Monoxide results in increased metabolism of XDH protein CTD PMID:1447108 carbon nanotube increases expression ISO Xdh (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 carboplatin affects activity EXP 6480464 Carboplatin affects the activity of XDH protein CTD PMID:15225673 carvacrol multiple interactions ISO Xdh (Mus musculus) 6480464 carvacrol inhibits the reaction [Benzo(a)pyrene results in increased activity of XDH protein] CTD PMID:29019276 Chloramine multiple interactions EXP 6480464 Dithiothreitol inhibits the reaction [chloramine affects the activity of XDH protein] and Methionine inhibits the reaction [chloramine affects the activity of XDH protein] CTD PMID:19527742 Chloramine affects activity EXP 6480464 chloramine affects the activity of XDH protein CTD PMID:19527742 chloroprene increases expression ISO Xdh (Mus musculus) 6480464 Chloroprene results in increased expression of XDH mRNA CTD PMID:23125180 chlorpyrifos multiple interactions EXP 6480464 3-(indol-3-yl)propionic acid inhibits the reaction [Chlorpyrifos results in increased activity of XDH protein] more ... CTD PMID:31400774 and PMID:34678318 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of XDH mRNA CTD PMID:31400774 chlorpyrifos increases activity EXP 6480464 Chlorpyrifos results in increased activity of XDH protein and Chlorpyrifos results in increased activity of XDH protein modified form CTD PMID:31400774 and PMID:34678318 chlorzoxazone affects metabolic processing ISO XDH (Homo sapiens) 6480464 XDH protein affects the metabolism of Chlorzoxazone CTD PMID:14586387 chromium(6+) affects expression ISO Xdh (Mus musculus) 6480464 chromium hexavalent ion affects the expression of XDH mRNA CTD PMID:28472532 cis-caffeic acid multiple interactions ISO Xdh (Mus musculus) 6480464 caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [XDH protein results in increased chemical synthesis of Uric Acid]] and caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein] CTD PMID:22036979 cisplatin increases expression ISO Xdh (Mus musculus) 6480464 Cisplatin results in increased expression of XDH mRNA CTD PMID:21151649 cisplatin multiple interactions ISO XDH (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of XDH mRNA CTD PMID:27392435 cisplatin increases expression ISO XDH (Homo sapiens) 6480464 Cisplatin results in increased expression of XDH mRNA CTD PMID:27392435 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of XDH protein CTD PMID:25640527 cisplatin multiple interactions EXP 6480464 Plant Extracts inhibits the reaction [Cisplatin results in increased expression of XDH protein] CTD PMID:25640527 clofibrate decreases activity EXP 6480464 Clofibrate results in decreased activity of XDH protein CTD PMID:8373410 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of XDH mRNA CTD PMID:17602206 cobalt dichloride multiple interactions EXP 6480464 [Xanthine co-treated with XDH protein] inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein] CTD PMID:12595275 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of XDH mRNA CTD PMID:24386269 cocaine multiple interactions EXP 6480464 acetovanillone inhibits the reaction [Cocaine results in increased activity of XDH protein] CTD PMID:17217956 cocaine increases activity EXP 6480464 Cocaine results in increased activity of XDH protein CTD PMID:17217956 copper atom decreases expression EXP 6480464 Copper results in decreased expression of XDH mRNA CTD PMID:30556269 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of XDH mRNA CTD PMID:30556269 cordycepin affects expression ISO XDH (Homo sapiens) 6480464 cordycepin affects the expression of XDH mRNA CTD PMID:28099944 crocidolite asbestos increases expression ISO XDH (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased expression of XDH mRNA CTD PMID:25351596 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Indomethacin results in increased activity of XDH protein] CTD PMID:17351913 cycloartenol multiple interactions ISO Xdh (Mus musculus) 6480464 cycloartenol inhibits the reaction [Benzoyl Peroxide results in increased activity of XDH protein] CTD PMID:12804013 cyclophosphamide increases activity EXP 6480464 Cyclophosphamide results in increased activity of XDH protein CTD PMID:25753322 cyclophosphamide multiple interactions EXP 6480464 Rutin inhibits the reaction [Cyclophosphamide results in increased activity of XDH protein] CTD PMID:25753322 cyclosporin A affects expression ISO XDH (Homo sapiens) 6480464 Cyclosporine affects the expression of XDH mRNA CTD PMID:20106945 cyclosporin A increases expression ISO XDH (Homo sapiens) 6480464 Cyclosporine results in increased expression of XDH mRNA CTD PMID:27989131 cyhalothrin decreases expression EXP 6480464 cyhalothrin results in decreased expression of XDH mRNA CTD PMID:29727961 D-glucose multiple interactions EXP 6480464 [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucose results in increased abundance of Proteoglycans] and [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucose results in increased expression of B3GAT3 mRNA] CTD PMID:11801247 DDT decreases expression EXP 6480464 DDT results in decreased expression of XDH mRNA CTD PMID:30207508 dehydroepiandrosterone decreases activity EXP 6480464 Dehydroepiandrosterone results in decreased activity of XDH protein CTD PMID:8373410 dexamethasone multiple interactions ISO Xdh (Mus musculus) 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of XDH mRNA more ... CTD PMID:16054899 dexamethasone increases expression ISO Xdh (Mus musculus) 6480464 Dexamethasone results in increased expression of XDH mRNA CTD PMID:22733784 dexamethasone multiple interactions EXP 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of XDH mRNA] CTD PMID:20032058 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of XDH mRNA and Dexamethasone results in increased expression of XDH protein CTD PMID:12826072 and PMID:20032058 dextromethorphan affects metabolic processing ISO XDH (Homo sapiens) 6480464 XDH protein affects the metabolism of Dextromethorphan CTD PMID:15199075 diallyl trisulfide multiple interactions ISO Xdh (Mus musculus) 6480464 diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased secretion of and results in increased activity of XDH protein] CTD PMID:36796188 diallyl trisulfide increases expression ISO XDH (Homo sapiens) 6480464 diallyl trisulfide results in increased expression of XDH mRNA CTD PMID:34995734 diethylstilbestrol increases expression ISO Xdh (Mus musculus) 6480464 Diethylstilbestrol results in increased expression of XDH mRNA CTD PMID:15289156 diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of XDH mRNA CTD PMID:15890375 diisopropyl fluorophosphate multiple interactions EXP 6480464 Isoflurophate promotes the reaction [XDH protein alternative form results in increased abundance of F2-Isoprostanes] more ... CTD PMID:9789800 diisopropyl fluorophosphate increases expression EXP 6480464 Isoflurophate results in increased expression of XDH protein alternative form CTD PMID:9789800 diosmin multiple interactions EXP 6480464 Diosmin inhibits the reaction [2-Acetylaminofluorene results in increased activity of XDH protein] CTD PMID:23665045 diosmin multiple interactions ISO Xdh (Mus musculus) 6480464 Diosmin inhibits the reaction [Benzo(a)pyrene results in increased expression of XDH protein] CTD PMID:32061149 dioxygen increases activity ISO XDH (Homo sapiens) 6480464 Oxygen deficiency results in increased activity of XDH protein CTD PMID:16226770 dioxygen multiple interactions EXP 6480464 [Xanthine co-treated with XDH protein] inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein] more ... CTD PMID:11278616 and PMID:12595275 dioxygen multiple interactions ISO XDH (Homo sapiens) 6480464 [[Oxygen deficiency results in increased abundance of Hypoxanthine] affects the reaction [XDH protein affects the metabolism of Hypoxanthine]] which affects the abundance of Hydroxyl Radical more ... CTD PMID:16226770 and PMID:7929072 diquat increases expression ISO Xdh (Mus musculus) 6480464 Diquat results in increased expression of XDH mRNA CTD PMID:36851058 diuron decreases expression EXP 6480464 Diuron results in decreased expression of XDH mRNA CTD PMID:25152437 dizocilpine maleate multiple interactions EXP 6480464 Dizocilpine Maleate inhibits the reaction [ammonium acetate affects the activity of XDH protein] CTD PMID:12885441 doxorubicin increases activity EXP 6480464 Doxorubicin results in increased activity of XDH protein CTD PMID:12965118 doxorubicin multiple interactions ISO Xdh (Mus musculus) 6480464 [[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of XDH mRNA CTD PMID:21040762 doxorubicin multiple interactions EXP 6480464 erdosteine inhibits the reaction [Doxorubicin results in increased activity of XDH protein] CTD PMID:12965118 doxorubicin increases expression ISO Xdh (Mus musculus) 6480464 Doxorubicin results in increased expression of XDH mRNA CTD PMID:19286953 edaravone multiple interactions EXP 6480464 Edaravone inhibits the reaction [Valproic Acid results in increased activity of XDH protein] CTD PMID:34309930 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of XDH mRNA CTD PMID:29391264 enzyme inhibitor increases activity EXP 6480464 Enzyme Inhibitors results in increased activity of XDH protein CTD PMID:12009427 epoxiconazole decreases expression ISO Xdh (Mus musculus) 6480464 epoxiconazole results in decreased expression of XDH mRNA CTD PMID:35436446 erdosteine multiple interactions EXP 6480464 erdosteine inhibits the reaction [Doxorubicin results in increased activity of XDH protein] CTD PMID:12965118 ethanol increases expression ISO XDH (Homo sapiens) 6480464 Ethanol results in increased expression of XDH mRNA and Ethanol results in increased expression of XDH protein CTD PMID:18845238 ethanol multiple interactions EXP 6480464 myricetin inhibits the reaction [Ethanol results in increased activity of XDH protein] CTD PMID:35156864 ethanol increases activity EXP 6480464 Ethanol results in increased activity of XDH protein CTD PMID:35156864 ethanol increases expression EXP 6480464 Ethanol results in increased expression of XDH mRNA CTD PMID:23273579 ethylenediaminetetraacetic acid multiple interactions ISO Xdh (Mus musculus) 6480464 [XDH protein co-treated with Edetic Acid analog] results in increased oxidation of Uroporphyrinogens and CAT inhibits the reaction [[XDH protein co-treated with Edetic Acid analog] results in increased oxidation of Uroporphyrinogens] CTD PMID:1567206 febuxostat decreases activity ISO XDH (Homo sapiens) 6480464 Febuxostat results in decreased activity of XDH protein CTD PMID:35866629 fipronil multiple interactions EXP 6480464 Allopurinol inhibits the reaction [fipronil results in increased activity of XDH protein] CTD PMID:36916050 fipronil increases activity EXP 6480464 fipronil results in increased activity of XDH protein CTD PMID:36916050 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of XDH mRNA CTD PMID:18035473 fluocinolone acetonide multiple interactions ISO Xdh (Mus musculus) 6480464 Fluocinolone Acetonide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein] CTD PMID:3677084 fluoranthene increases expression ISO Xdh (Mus musculus) 6480464 fluoranthene results in increased expression of XDH mRNA CTD PMID:28329830 fluoranthene multiple interactions ISO Xdh (Mus musculus) 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of XDH mRNA CTD PMID:28329830 formaldehyde increases expression ISO XDH (Homo sapiens) 6480464 Formaldehyde results in increased expression of XDH mRNA CTD PMID:27664576 fructose multiple interactions ISO XDH (Homo sapiens) 6480464 Fructose promotes the reaction [XDH protein results in increased chemical synthesis of Uric Acid] and XDH protein promotes the reaction [Fructose results in increased abundance of Reactive Oxygen Species] CTD PMID:19158351 fructose multiple interactions EXP 6480464 Glutamine inhibits the reaction [Fructose results in increased activity of XDH protein] CTD PMID:31233715 fructose increases activity EXP 6480464 Fructose results in increased activity of XDH protein CTD PMID:31233715 gallic acid multiple interactions EXP 6480464 Gallic Acid inhibits the reaction [Zearalenone results in increased activity of XDH protein] CTD PMID:34723416 genistein increases expression ISO Xdh (Mus musculus) 6480464 Genistein results in increased expression of XDH mRNA CTD PMID:15289156 glucose multiple interactions EXP 6480464 [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucose results in increased abundance of Proteoglycans] and [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucose results in increased expression of B3GAT3 mRNA] CTD PMID:11801247 glutathione multiple interactions EXP 6480464 [Xanthine co-treated with XDH protein] results in increased abundance of Glutathione CTD PMID:7743507 glyburide multiple interactions ISO Xdh (Mus musculus) 6480464 [Glyburide results in decreased activity of ABCC9 protein] which results in increased expression of XDH protein CTD PMID:22622455 hydrogen peroxide multiple interactions EXP 6480464 [Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide more ... CTD PMID:23647015 hydrogen peroxide increases activity ISO XDH (Homo sapiens) 6480464 Hydrogen Peroxide results in increased activity of XDH protein CTD PMID:28285367 hydrogen peroxide multiple interactions ISO XDH (Homo sapiens) 6480464 Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased activity of XDH protein] CTD PMID:28285367 hydroxyl multiple interactions ISO XDH (Homo sapiens) 6480464 [[Oxygen deficiency results in increased abundance of Hypoxanthine] affects the reaction [XDH protein affects the metabolism of Hypoxanthine]] which affects the abundance of Hydroxyl Radical CTD PMID:7929072 hydroxyl increases abundance ISO XDH (Homo sapiens) 6480464 XDH protein results in increased abundance of Hydroxyl Radical CTD PMID:7929072 hydroxytyrosol multiple interactions EXP 6480464 3 more ... CTD PMID:26374991 hypoxanthine multiple interactions ISO XDH (Homo sapiens) 6480464 [[Oxygen deficiency results in increased abundance of Hypoxanthine] affects the reaction [XDH protein affects the metabolism of Hypoxanthine]] which affects the abundance of Hydroxyl Radical and [XDH protein co-treated with Hypoxanthine] results in increased secretion of CXCL8 protein CTD PMID:7929072 and PMID:8969274 hypoxanthine multiple interactions ISO Xdh (Mus musculus) 6480464 [Oxonic Acid analog co-treated with Hypoxanthine] results in increased activity of XDH protein more ... CTD PMID:34687833 hypoxanthine multiple interactions EXP 6480464 [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased abundance of Proteoglycans] more ... CTD PMID:11801247 hypoxanthine affects metabolic processing ISO XDH (Homo sapiens) 6480464 XDH protein affects the metabolism of Hypoxanthine CTD PMID:7929072 indometacin multiple interactions EXP 6480464 Allopurinol inhibits the reaction [Indomethacin results in increased activity of XDH protein] more ... CTD PMID:12498302 more ... indometacin increases expression EXP 6480464 Indomethacin results in increased expression of XDH mRNA CTD PMID:36868495 indometacin multiple interactions ISO XDH (Homo sapiens) 6480464 methyl arachidonylfluorophosphonate inhibits the reaction [Indomethacin results in increased activity of XDH protein] CTD PMID:19470405 indometacin increases activity ISO XDH (Homo sapiens) 6480464 Indomethacin results in increased activity of XDH protein CTD PMID:19470405 indometacin increases activity EXP 6480464 Indomethacin results in increased activity of XDH protein CTD PMID:12498302 more ... isoprenaline increases expression ISO Xdh (Mus musculus) 6480464 Isoproterenol results in increased expression of XDH mRNA CTD PMID:20003209 isoprenaline multiple interactions EXP 6480464 [Isoproterenol co-treated with POSTN protein] results in decreased expression of XDH mRNA CTD PMID:30303030 isotretinoin multiple interactions ISO Xdh (Mus musculus) 6480464 Isotretinoin inhibits the reaction [Benzoyl Peroxide results in increased activity of XDH protein] CTD PMID:15225900 L-1,4-dithiothreitol multiple interactions EXP 6480464 Dithiothreitol inhibits the reaction [chloramine affects the activity of XDH protein] CTD PMID:19527742 L-ascorbic acid multiple interactions ISO XDH (Homo sapiens) 6480464 Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased activity of XDH protein] CTD PMID:28285367 L-glutamine multiple interactions EXP 6480464 Glutamine inhibits the reaction [Fructose results in increased activity of XDH protein] CTD PMID:31233715 L-methionine multiple interactions EXP 6480464 Methionine inhibits the reaction [chloramine affects the activity of XDH protein] CTD PMID:19527742 lead(0) decreases expression ISO XDH (Homo sapiens) 6480464 Lead results in decreased expression of XDH mRNA CTD PMID:19921347 lipoic acid multiple interactions EXP 6480464 Thioctic Acid inhibits the reaction [Valproic Acid results in increased activity of XDH protein] CTD PMID:32662911 lipopolysaccharide multiple interactions ISO Xdh (Mus musculus) 6480464 [Lipopolysaccharides co-treated with Uric Acid] results in increased secretion of and results in increased activity of XDH protein and diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased secretion of and results in increased activity of XDH protein] CTD PMID:36796188 liraglutide multiple interactions ISO XDH (Homo sapiens) 6480464 Liraglutide inhibits the reaction [Pyruvaldehyde results in increased expression of XDH mRNA] CTD PMID:35985417 Lithospermic acid decreases activity EXP 6480464 lithospermic acid results in decreased activity of XDH protein CTD PMID:18694741 lupeol multiple interactions ISO Xdh (Mus musculus) 6480464 lupeol inhibits the reaction [Benzoyl Peroxide affects the activity of XDH protein] CTD PMID:15248479 mercaptopurine increases expression EXP 6480464 Mercaptopurine results in increased expression of XDH mRNA CTD PMID:22688000 mercaptopurine affects expression EXP 6480464 Mercaptopurine affects the expression of XDH mRNA CTD PMID:23358152 Mesaconitine increases expression EXP 6480464 mesaconitine results in increased expression of XDH protein CTD PMID:37182599 methamphetamine increases expression ISO Xdh (Mus musculus) 6480464 Methamphetamine results in increased expression of XDH mRNA CTD PMID:26307267 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of XDH mRNA CTD PMID:15890375 methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of XDH mRNA CTD PMID:30047161 methylglyoxal increases expression ISO XDH (Homo sapiens) 6480464 Pyruvaldehyde results in increased expression of XDH mRNA CTD PMID:35985417 methylglyoxal multiple interactions ISO XDH (Homo sapiens) 6480464 Liraglutide inhibits the reaction [Pyruvaldehyde results in increased expression of XDH mRNA] CTD PMID:35985417 methylisothiazolinone increases expression ISO XDH (Homo sapiens) 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of XDH mRNA CTD PMID:31629900 mitomycin C multiple interactions ISO XDH (Homo sapiens) 6480464 [Oxygen deficiency co-treated with Mitomycin] results in decreased activity of XDH protein and [Tetrachlorodibenzodioxin co-treated with Mitomycin co-treated with Oxygen deficiency] affects the activity of XDH protein CTD PMID:16226770 mitomycin C decreases activity ISO XDH (Homo sapiens) 6480464 Mitomycin results in decreased activity of XDH protein CTD PMID:16226770 molybdate multiple interactions ISO XDH (Homo sapiens) 6480464 [sodium molybdate(VI) results in increased abundance of molybdate] which results in decreased activity of XDH protein CTD PMID:34320920 monosodium L-glutamate multiple interactions ISO Xdh (Mus musculus) 6480464 [Fats and Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of XDH mRNA CTD PMID:23783067 myo-inositol hexakisphosphate decreases activity EXP 6480464 Phytic Acid results in decreased activity of XDH protein CTD PMID:14738912 myricetin multiple interactions EXP 6480464 [Xanthine co-treated with XDH protein] promotes the reaction [myricetin results in decreased activity of TXNRD1 protein modified form] and myricetin inhibits the reaction [Ethanol results in increased activity of XDH protein] CTD PMID:16618767 and PMID:35156864 N-acetyl-L-cysteine multiple interactions ISO XDH (Homo sapiens) 6480464 [MPO protein co-treated with XDH protein co-treated with Acetaldehyde] promotes the reaction [Serotonin binds to Acetylcysteine] CTD PMID:23009681 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of XDH mRNA CTD PMID:17602206 N-nitrosodimethylamine decreases expression EXP 6480464 Dimethylnitrosamine results in decreased expression of XDH mRNA CTD PMID:15890375 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of XDH mRNA CTD PMID:24136188 nickel atom increases expression ISO XDH (Homo sapiens) 6480464 Nickel results in increased expression of XDH mRNA CTD PMID:24768652 and PMID:25583101 nicorandil multiple interactions ISO Xdh (Mus musculus) 6480464 Nicorandil inhibits the reaction [AGT protein modified form results in increased expression of XDH protein] CTD PMID:22622455 nicorandil decreases expression EXP 6480464 Nicorandil results in decreased expression of XDH protein CTD PMID:22622455 nicotine increases activity EXP 6480464 Nicotine results in increased activity of XDH protein CTD PMID:31857090 nicotine multiple interactions EXP 6480464 Sodium Acetate inhibits the reaction [Nicotine results in increased activity of XDH protein] CTD PMID:31857090 nitric oxide multiple interactions ISO XDH (Homo sapiens) 6480464 XDH protein promotes the reaction [[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide] CTD PMID:20888885 nitroprusside multiple interactions EXP 6480464 [Xanthine co-treated with XDH protein] inhibits the reaction [Nitroprusside results in increased abundance of Cyclic GMP] CTD PMID:17339839 O-methyleugenol decreases expression ISO XDH (Homo sapiens) 6480464 methyleugenol results in decreased expression of XDH mRNA CTD PMID:32234424 obeticholic acid increases expression ISO XDH (Homo sapiens) 6480464 obeticholic acid results in increased expression of XDH mRNA CTD PMID:27939613 ochratoxin A increases expression ISO XDH (Homo sapiens) 6480464 ochratoxin A results in increased expression of XDH mRNA CTD PMID:17316727 ochratoxin A decreases expression ISO XDH (Homo sapiens) 6480464 ochratoxin A results in decreased expression of XDH mRNA CTD PMID:30559759 palytoxin increases expression ISO XDH (Homo sapiens) 6480464 palytoxin results in increased expression of XDH mRNA CTD PMID:23142474 paracetamol decreases expression ISO XDH (Homo sapiens) 6480464 Acetaminophen results in decreased expression of XDH mRNA CTD PMID:21420995 and PMID:29067470 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of XDH mRNA CTD PMID:33387578 paraquat increases activity EXP 6480464 Paraquat results in increased activity of XDH protein CTD PMID:10699569 paraquat increases expression ISO Xdh (Mus musculus) 6480464 Paraquat results in increased expression of XDH mRNA CTD PMID:21463325 pentachlorophenol increases expression ISO Xdh (Mus musculus) 6480464 Pentachlorophenol results in increased expression of XDH mRNA CTD PMID:23892564 pentanal increases expression ISO XDH (Homo sapiens) 6480464 pentanal results in increased expression of XDH mRNA CTD PMID:26079696 pentetrazol multiple interactions EXP 6480464 Vitamin U inhibits the reaction [Pentylenetetrazole results in increased activity of XDH protein] CTD PMID:35833322 pentetrazol increases activity EXP 6480464 Pentylenetetrazole results in increased activity of XDH protein CTD PMID:35833322 perfluorononanoic acid decreases expression ISO XDH (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of XDH mRNA CTD PMID:32588087 perfluorooctanoic acid decreases activity EXP 6480464 perfluorooctanoic acid results in decreased activity of XDH protein CTD PMID:8373410 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of XDH mRNA CTD PMID:19162173 permethrin increases expression ISO XDH (Homo sapiens) 6480464 Permethrin results in increased expression of XDH mRNA CTD PMID:37047231 phenobarbital multiple interactions ISO Xdh (Mus musculus) 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of XDH mRNA] CTD PMID:19482888 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of XDH mRNA CTD PMID:23273579 phenobarbital increases expression ISO Xdh (Mus musculus) 6480464 Phenobarbital results in increased expression of XDH mRNA CTD PMID:19482888 PhIP decreases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in decreased expression of XDH mRNA CTD PMID:12376462 phorbol 13-acetate 12-myristate multiple interactions ISO Xdh (Mus musculus) 6480464 Allopurinol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein] more ... CTD PMID:22036979 and PMID:3677084 phorbol 13-acetate 12-myristate increases activity ISO Xdh (Mus musculus) 6480464 Tetradecanoylphorbol Acetate results in increased activity of XDH protein CTD PMID:22036979 and PMID:3677084 piperonyl butoxide decreases expression EXP 6480464 Piperonyl Butoxide results in decreased expression of XDH mRNA CTD PMID:15890375 pirinixic acid multiple interactions ISO XDH (Homo sapiens) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of XDH mRNA CTD PMID:19710929 pirinixic acid decreases expression ISO Xdh (Mus musculus) 6480464 pirinixic acid results in decreased expression of XDH mRNA CTD PMID:23811191 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of XDH mRNA CTD PMID:12832660 more ... pirinixic acid multiple interactions ISO Xdh (Mus musculus) 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of XDH mRNA] CTD PMID:20059764 pirinixic acid increases expression ISO Xdh (Mus musculus) 6480464 pirinixic acid results in increased expression of XDH mRNA CTD PMID:18301758 more ... Potassium 2,6-dihydroxytriazinecarboxylate multiple interactions ISO Xdh (Mus musculus) 6480464 [Biological Products co-treated with potassium oxonate] results in increased activity of XDH protein more ... CTD PMID:34044073 potassium bromate increases activity EXP 6480464 potassium bromate results in increased activity of XDH protein CTD PMID:25213677 potassium bromate multiple interactions EXP 6480464 Taurine inhibits the reaction [potassium bromate results in increased activity of XDH protein] CTD PMID:25213677 pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of XDH mRNA CTD PMID:19162173 and PMID:30047161 progesterone multiple interactions ISO XDH (Homo sapiens) 6480464 [Estradiol co-treated with Progesterone] results in increased expression of XDH mRNA CTD PMID:20660070 progesterone increases expression EXP 6480464 Progesterone results in increased expression of XDH mRNA CTD PMID:20726854 propanal increases expression ISO XDH (Homo sapiens) 6480464 propionaldehyde results in increased expression of XDH mRNA CTD PMID:26079696 propiconazole decreases expression ISO Xdh (Mus musculus) 6480464 propiconazole results in decreased expression of XDH mRNA CTD PMID:21278054 purine-6-thiol increases expression EXP 6480464 Mercaptopurine results in increased expression of XDH mRNA CTD PMID:22688000 purine-6-thiol affects expression EXP 6480464 Mercaptopurine affects the expression of XDH mRNA CTD PMID:23358152 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [[Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide] more ... CTD PMID:23647015 more ... quercetin increases activity ISO XDH (Homo sapiens) 6480464 Quercetin results in increased activity of XDH protein alternative form CTD PMID:19215233 rac-lactic acid decreases expression ISO XDH (Homo sapiens) 6480464 Lactic Acid results in decreased expression of XDH mRNA CTD PMID:30851411 raloxifene increases activity ISO XDH (Homo sapiens) 6480464 Raloxifene Hydrochloride results in increased activity of XDH protein CTD PMID:20888885 raloxifene multiple interactions ISO XDH (Homo sapiens) 6480464 XDH protein promotes the reaction [[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide] CTD PMID:20888885 reactive oxygen species increases abundance EXP 6480464 XDH protein alternative form results in increased abundance of Reactive Oxygen Species CTD PMID:9789800 reactive oxygen species multiple interactions ISO Xdh (Mus musculus) 6480464 [XDH protein results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of IL1B mRNA and [XDH protein results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of TNF mRNA CTD PMID:7695923 reactive oxygen species increases chemical synthesis ISO Xdh (Mus musculus) 6480464 XDH protein results in increased chemical synthesis of Reactive Oxygen Species CTD PMID:7695923 reactive oxygen species multiple interactions ISO XDH (Homo sapiens) 6480464 XDH protein promotes the reaction [Fructose results in increased abundance of Reactive Oxygen Species] CTD PMID:19158351 reactive oxygen species multiple interactions EXP 6480464 Desoxycorticosterone promotes the reaction [XDH protein results in increased chemical synthesis of Reactive Oxygen Species] and Isoflurophate promotes the reaction [XDH protein alternative form results in increased abundance of Reactive Oxygen Species] CTD PMID:16271043 and PMID:9789800 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [Rotenone results in increased activity of XDH protein] CTD PMID:27016191 rotenone decreases activity ISO XDH (Homo sapiens) 6480464 Rotenone results in decreased activity of XDH protein CTD PMID:21570952 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of XDH mRNA CTD PMID:28374803 rotenone multiple interactions EXP 6480464 Resveratrol inhibits the reaction [Rotenone results in increased activity of XDH protein] and taxifolin inhibits the reaction [Rotenone results in increased activity of XDH protein] CTD PMID:27016191 and PMID:35187747 rotenone increases activity EXP 6480464 Rotenone results in increased activity of XDH protein CTD PMID:27016191 and PMID:35187747 rutin multiple interactions EXP 6480464 Rutin inhibits the reaction [Cyclophosphamide results in increased activity of XDH protein] CTD PMID:25753322 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [Oxygen deficiency results in increased phosphorylation of and results in increased activity of XDH protein] CTD PMID:11278616 Senkirkine decreases expression ISO XDH (Homo sapiens) 6480464 senkirkine results in decreased expression of XDH mRNA CTD PMID:26100227 serotonin multiple interactions ISO XDH (Homo sapiens) 6480464 [MPO protein co-treated with XDH protein co-treated with Acetaldehyde co-treated with Serotonin] affects the metabolism of and binds to GAPDH protein and [MPO protein co-treated with XDH protein co-treated with Acetaldehyde] promotes the reaction [Serotonin binds to Acetylcysteine] CTD PMID:23009681 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of XDH mRNA CTD PMID:21602193 silicon dioxide increases expression ISO XDH (Homo sapiens) 6480464 Silicon Dioxide results in increased expression of XDH mRNA CTD PMID:25351596 silver atom increases expression ISO Xdh (Mus musculus) 6480464 Silver results in increased expression of XDH mRNA CTD PMID:27131904 silver(0) increases expression ISO Xdh (Mus musculus) 6480464 Silver results in increased expression of XDH mRNA CTD PMID:27131904 sodium acetate trihydrate multiple interactions EXP 6480464 Sodium Acetate inhibits the reaction [Nicotine results in increased activity of XDH protein] CTD PMID:31857090 sodium arsenate multiple interactions ISO XDH (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of XDH mRNA CTD PMID:32525701 sodium arsenite decreases methylation ISO XDH (Homo sapiens) 6480464 sodium arsenite results in decreased methylation of XDH gene CTD PMID:24570342 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of XDH protein CTD PMID:29459688 sodium arsenite decreases expression ISO XDH (Homo sapiens) 6480464 sodium arsenite results in decreased expression of XDH mRNA CTD PMID:29301061 sodium arsenite increases expression ISO XDH (Homo sapiens) 6480464 sodium arsenite results in increased expression of XDH mRNA CTD PMID:24570342 sodium benzoate increases activity EXP 6480464 Sodium Benzoate results in increased activity of XDH protein CTD PMID:32911041 sodium disulfite multiple interactions EXP 6480464 GHRL protein inhibits the reaction [sodium metabisulfite results in increased activity of XDH protein] CTD PMID:25486021 sodium disulfite increases activity EXP 6480464 sodium metabisulfite results in increased activity of XDH protein CTD PMID:25486021 sodium fluoride decreases expression ISO Xdh (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of XDH mRNA CTD PMID:27862939 sodium molybdate (anhydrous) multiple interactions ISO XDH (Homo sapiens) 6480464 [sodium molybdate(VI) results in increased abundance of molybdate] which results in decreased activity of XDH protein CTD PMID:34320920 sodium nitrate increases metabolic processing ISO Xdh (Mus musculus) 6480464 XDH protein results in increased metabolism of sodium nitrate CTD PMID:20142047 sodium tungstate multiple interactions EXP 6480464 sodium tungstate(VI) inhibits the reaction [Carbon Tetrachloride results in increased activity of XDH protein] CTD PMID:17727797 sodium tungstate multiple interactions ISO XDH (Homo sapiens) 6480464 [sodium tungstate(VI) results in increased abundance of Tungsten] which results in decreased activity of XDH protein CTD PMID:34320920 streptozocin affects activity EXP 6480464 Streptozocin affects the activity of XDH protein CTD PMID:23647015 streptozocin increases activity EXP 6480464 Streptozocin results in increased activity of XDH protein modified form CTD PMID:31400774 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of XDH mRNA CTD PMID:31400774 streptozocin multiple interactions EXP 6480464 [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased activity of XDH protein modified form more ... CTD PMID:23647015 and PMID:31400774 sulfadimethoxine decreases expression EXP 6480464 Sulfadimethoxine results in decreased expression of XDH mRNA CTD PMID:30047161 superoxide multiple interactions ISO XDH (Homo sapiens) 6480464 [[Xanthine co-treated with XDH protein] results in increased abundance of Superoxides] which results in increased secretion of TGFB1 protein more ... CTD PMID:19268487 and PMID:19555678 superoxide increases chemical synthesis ISO XDH (Homo sapiens) 6480464 XDH protein results in increased chemical synthesis of Superoxides CTD PMID:19555678 taurine multiple interactions EXP 6480464 Taurine inhibits the reaction [Alloxan results in increased activity of XDH protein] and Taurine inhibits the reaction [potassium bromate results in increased activity of XDH protein] CTD PMID:22138235 and PMID:25213677 testosterone multiple interactions EXP 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of XDH mRNA more ... CTD PMID:20032058 more ... testosterone increases activity EXP 6480464 Testosterone results in increased activity of XDH protein modified form CTD PMID:32628957 tetrachloromethane affects expression ISO Xdh (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of XDH mRNA CTD PMID:17484886 tetrachloromethane increases activity EXP 6480464 Carbon Tetrachloride results in increased activity of XDH protein CTD PMID:30825423 tetrachloromethane multiple interactions EXP 6480464 12-tungstophosphoric acid inhibits the reaction [Carbon Tetrachloride results in increased activity of XDH protein] more ... CTD PMID:17727797 and PMID:30825423 thioacetamide multiple interactions EXP 6480464 12-tungstophosphoric acid inhibits the reaction [Thioacetamide results in increased activity of XDH protein] and Thioacetamide results in increased expression of and results in increased activity of XDH protein CTD PMID:17727797 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of XDH mRNA CTD PMID:34492290 toluene affects expression EXP 6480464 Toluene affects the expression of XDH mRNA CTD PMID:21827849 toluene increases expression EXP 6480464 Toluene results in increased expression of XDH mRNA CTD PMID:22967744 trans-caffeic acid multiple interactions ISO Xdh (Mus musculus) 6480464 caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [XDH protein results in increased chemical synthesis of Uric Acid]] and caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein] CTD PMID:22036979 trichostatin A decreases expression ISO XDH (Homo sapiens) 6480464 trichostatin A results in decreased expression of XDH mRNA CTD PMID:24935251 trimellitic anhydride decreases methylation ISO Xdh (Mus musculus) 6480464 trimellitic anhydride results in decreased methylation of XDH promoter CTD PMID:24675093 trovafloxacin multiple interactions ISO Xdh (Mus musculus) 6480464 [trovafloxacin co-treated with lipopolysaccharide and E coli O55-B5] results in increased expression of XDH mRNA CTD PMID:18930950 tubocurarine multiple interactions EXP 6480464 Tubocurarine inhibits the reaction [Isoflurophate results in increased expression of XDH protein alternative form] CTD PMID:9789800 tungsten decreases activity ISO Xdh (Mus musculus) 6480464 Tungsten results in decreased activity of XDH protein CTD PMID:17023262 tungsten multiple interactions ISO XDH (Homo sapiens) 6480464 [sodium tungstate(VI) results in increased abundance of Tungsten] which results in decreased activity of XDH protein CTD PMID:34320920 tungsten decreases activity EXP 6480464 Tungsten results in decreased activity of XDH protein CTD PMID:1447108 tungsten multiple interactions EXP 6480464 [Tungsten co-treated with Puromycin Aminonucleoside] results in decreased activity of XDH protein CTD PMID:7583048 valproic acid increases expression ISO XDH (Homo sapiens) 6480464 Valproic Acid results in increased expression of XDH mRNA CTD PMID:29154799 valproic acid multiple interactions EXP 6480464 Edaravone inhibits the reaction [Valproic Acid results in increased activity of XDH protein] and Thioctic Acid inhibits the reaction [Valproic Acid results in increased activity of XDH protein] CTD PMID:32662911 and PMID:34309930 valproic acid increases activity EXP 6480464 Valproic Acid results in increased activity of XDH protein CTD PMID:32662911 more ... vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of XDH mRNA CTD PMID:19015723 vitamin E multiple interactions EXP 6480464 Vitamin E inhibits the reaction [Petroleum results in increased activity of XDH protein] CTD PMID:25046308 zearalenone multiple interactions EXP 6480464 Gallic Acid inhibits the reaction [Zearalenone results in increased activity of XDH protein] CTD PMID:34723416 zearalenone increases activity EXP 6480464 Zearalenone results in increased activity of XDH protein CTD PMID:34723416 zinc atom multiple interactions EXP 6480464 Zinc inhibits the reaction [Indomethacin results in increased activity of XDH protein] CTD PMID:12566098 zinc atom multiple interactions ISO XDH (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of XDH mRNA CTD PMID:18593933 zinc atom increases expression EXP 6480464 Zinc results in increased expression of XDH mRNA CTD PMID:17074742 zinc sulfate increases expression EXP 6480464 Zinc Sulfate results in increased expression of XDH mRNA CTD PMID:17074742 zinc(0) multiple interactions EXP 6480464 Zinc inhibits the reaction [Indomethacin results in increased activity of XDH protein] CTD PMID:12566098 zinc(0) increases expression EXP 6480464 Zinc results in increased expression of XDH mRNA CTD PMID:17074742 zinc(0) multiple interactions ISO XDH (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of XDH mRNA CTD PMID:18593933 zoledronic acid increases expression ISO XDH (Homo sapiens) 6480464 zoledronic acid results in increased expression of XDH mRNA CTD PMID:24714768