Selenop (selenoprotein P) - Rat Genome Database

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Gene: Selenop (selenoprotein P) Rattus norvegicus
Analyze
Symbol: Selenop
Name: selenoprotein P
RGD ID: 3660
Description: Predicted to enable selenium binding activity. Involved in response to selenium ion. Predicted to be located in extracellular space. Predicted to be active in extracellular region. Orthologous to human SELENOP (selenoprotein P); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: selenoprotein P, plasma, 1; seP; Sepp1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8254,225,736 - 54,236,022 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl254,225,152 - 54,236,019 (+)EnsemblGRCr8
mRatBN7.2252,498,123 - 52,508,409 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl252,498,339 - 52,508,852 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx259,598,067 - 59,608,378 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0257,656,824 - 57,667,108 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0252,686,704 - 52,697,013 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0253,105,912 - 53,116,198 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl253,109,684 - 53,114,858 (+)Ensemblrn6Rnor6.0
Rnor_5.0272,138,104 - 72,148,390 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4252,451,883 - 52,462,263 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera248,212,876 - 48,223,163 (+)NCBICelera
RGSC_v3.1252,380,331 - 52,390,794 (+)NCBI
Cytogenetic Map2q16NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(2,4,5-trichlorophenoxy)acetic acid  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
ammonium chloride  (EXP)
Aroclor 1254  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
Butylbenzyl phthalate  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
cerium trichloride  (ISO)
chlorpyrifos  (ISO)
clofibrate  (ISO)
clorgyline  (ISO)
colforsin daropate hydrochloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (EXP)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
DDT  (EXP)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
diethyl maleate  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (EXP,ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (EXP,ISO)
Enterolactone  (ISO)
entinostat  (ISO)
enzalutamide  (ISO)
ethanol  (ISO)
flutamide  (EXP)
furan  (EXP)
glucose  (EXP)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
indometacin  (ISO)
isoprenaline  (ISO)
lanthanum trichloride  (ISO)
lead diacetate  (EXP)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
lycopene  (ISO)
medroxyprogesterone acetate  (ISO)
menadione  (ISO)
mercury atom  (ISO)
mercury dibromide  (ISO)
mercury(0)  (ISO)
metformin  (EXP)
methamphetamine  (EXP)
methidathion  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
Muraglitazar  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nitrofen  (EXP)
ochratoxin A  (EXP)
okadaic acid  (ISO)
ozone  (EXP,ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (EXP)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
PhIP  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP,ISO)
progesterone  (EXP)
propanal  (ISO)
Pyridostigmine bromide  (EXP)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
selenium atom  (EXP,ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
streptozocin  (ISO)
sulforaphane  (ISO)
tamoxifen  (EXP,ISO)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (EXP)
testosterone  (EXP)
tetrachloromethane  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
tremolite asbestos  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
wortmannin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. The cDNA for rat selenoprotein P contains 10 TGA codons in the open reading frame. Hill KE, etal., J Biol Chem 1991 Jun 5;266(16):10050-3.
4. Expression of Selenoprotein Genes and Association with Selenium Status in Colorectal Adenoma and Colorectal Cancer. Hughes DJ, etal., Nutrients. 2018 Nov 21;10(11). pii: nu10111812. doi: 10.3390/nu10111812.
5. Mass spectrometric characterization of full-length rat selenoprotein P and three isoforms shortened at the C terminus. Evidence that three UGA codons in the mRNA open reading frame have alternative functions of specifying selenocysteine insertion or translation termination. Ma S, etal., J Biol Chem 2002 Apr 12;277(15):12749-54.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Molecular cloning of cDNA encoding a bovine selenoprotein P-like protein containing 12 selenocysteines and a (His-Pro) rich domain insertion, and its regional expression. Saijoh K, etal., Brain Res Mol Brain Res 1995 Jun;30(2):301-11.
12. Selenium requirements are higher for glutathione peroxidase-1 mRNA than gpx1 activity in rat testis. Schriever SC, etal., Exp Biol Med (Maywood). 2009 May;234(5):513-21. Epub 2009 Feb 20.
13. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
14. Selenium and Copper as Biomarkers for Pulmonary Arterial Hypertension in Systemic Sclerosis. Sun Q, etal., Nutrients. 2020 Jun 25;12(6):1894. doi: 10.3390/nu12061894.
Additional References at PubMed
PMID:7931697   PMID:8889548   PMID:12574155   PMID:12775843   PMID:12911312   PMID:14664694   PMID:14704310   PMID:15489334   PMID:15712351   PMID:17314095   PMID:17986386   PMID:18972406  
PMID:19199708   PMID:20360971   PMID:20959537   PMID:22479358   PMID:22761431   PMID:23064117   PMID:23533145   PMID:24157689   PMID:24257750   PMID:24274065   PMID:25063811   PMID:27645994  
PMID:28465347   PMID:29636330  


Genomics

Comparative Map Data
Selenop
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8254,225,736 - 54,236,022 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl254,225,152 - 54,236,019 (+)EnsemblGRCr8
mRatBN7.2252,498,123 - 52,508,409 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl252,498,339 - 52,508,852 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx259,598,067 - 59,608,378 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0257,656,824 - 57,667,108 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0252,686,704 - 52,697,013 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0253,105,912 - 53,116,198 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl253,109,684 - 53,114,858 (+)Ensemblrn6Rnor6.0
Rnor_5.0272,138,104 - 72,148,390 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4252,451,883 - 52,462,263 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera248,212,876 - 48,223,163 (+)NCBICelera
RGSC_v3.1252,380,331 - 52,390,794 (+)NCBI
Cytogenetic Map2q16NCBI
SELENOP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38542,799,880 - 42,811,892 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl542,799,880 - 42,887,392 (-)Ensemblhg38GRCh38
GRCh37542,799,982 - 42,811,994 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36542,835,739 - 42,847,781 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34542,835,746 - 42,847,717NCBI
Celera542,689,516 - 42,701,558 (-)NCBICelera
Cytogenetic Map5p12NCBI
HuRef542,751,403 - 42,763,445 (-)NCBIHuRef
CHM1_1542,801,878 - 42,813,920 (-)NCBICHM1_1
T2T-CHM13v2.0543,052,823 - 43,064,836 (-)NCBIT2T-CHM13v2.0
Selenop
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39153,300,249 - 3,309,992 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl153,298,029 - 3,309,990 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38153,270,767 - 3,280,510 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl153,268,547 - 3,280,508 (+)Ensemblmm10GRCm38
MGSCv37153,220,767 - 3,230,508 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36153,220,996 - 3,230,508 (+)NCBIMGSCv36mm8
Celera153,135,278 - 3,145,023 (+)NCBICelera
Cytogenetic Map15A1NCBI
cM Map151.84NCBI
Selenop
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542626,954,317 - 26,958,569 (-)Ensembl
ChiLan1.0NW_00495542626,951,003 - 26,961,839 (-)NCBIChiLan1.0ChiLan1.0
SELENOP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2467,522,907 - 67,535,008 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1565,676,533 - 65,688,634 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0567,570,087 - 67,582,192 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1572,615,983 - 72,628,069 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl572,619,607 - 72,627,213 (+)EnsemblpanPan2panpan1.1
SELENOP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1466,953,060 - 66,964,162 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl466,956,405 - 66,959,043 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha466,635,228 - 66,646,329 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0467,462,747 - 67,473,870 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl467,466,077 - 67,468,723 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1467,206,571 - 67,217,687 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0467,337,043 - 67,348,110 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0467,872,590 - 67,883,663 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Selenop
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213231,204,901 - 231,215,935 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936518159,473 - 163,110 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936518155,905 - 166,932 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SELENOP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1627,537,885 - 27,631,130 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11627,537,885 - 27,547,863 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21629,021,931 - 29,031,923 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SELENOP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1441,544,098 - 41,556,152 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607131,987,207 - 31,999,405 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Selenop
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475912,207,251 - 12,218,857 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Selenop
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13176,747,324 - 176,757,328 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Selenop
48 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21332504158325041Rat
7387318Stl32Serum triglyceride level QTL 323.20.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)22411781369117813Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23675034481750344Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1579916Bp270Blood pressure QTL 2700.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21605188361051883Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22203804467038044Rat
731166Mamtr2Mammary tumor resistance QTL 20.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358154623581Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)240306867124537199Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22888999173889991Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)241801363104744824Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21436870759368707Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24490435585286097Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)244537979112567334Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979159440891Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266683465677Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)25126685996266859Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)238426449111295694Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21822713763227137Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23686864381868643Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)24490435589904355Rat
1582246Cm60Cardiac mass QTL 605.8heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)23326999678269996Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266673652666Rat

Markers in Region
D2Got311  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2252,499,346 - 52,499,525 (+)MAPPERmRatBN7.2
Rnor_6.0253,107,136 - 53,107,314NCBIRnor6.0
Rnor_5.0272,139,328 - 72,139,506UniSTSRnor5.0
RGSC_v3.4252,453,107 - 52,453,285UniSTSRGSC3.4
Celera248,214,100 - 48,214,278UniSTS
Cytogenetic Map2q16UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001083911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC059137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC072539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF389559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB699091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB745388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D25221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN933732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ082498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M63574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000086590   ⟹   ENSRNOP00000069020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl254,225,152 - 54,236,019 (+)Ensembl
mRatBN7.2 Ensembl252,498,339 - 52,508,852 (+)Ensembl
Rnor_6.0 Ensembl253,109,684 - 53,114,858 (+)Ensembl
RefSeq Acc Id: NM_001083911   ⟹   NP_001077380
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8254,225,736 - 54,236,022 (+)NCBI
mRatBN7.2252,498,123 - 52,508,409 (+)NCBI
Rnor_6.0253,105,912 - 53,116,198 (+)NCBI
Rnor_5.0272,138,104 - 72,148,390 (+)NCBI
RGSC_v3.4252,451,883 - 52,462,263 (+)RGD
Celera248,212,876 - 48,223,163 (+)RGD
Sequence:
RefSeq Acc Id: NM_019192   ⟹   NP_062065
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8254,225,912 - 54,236,022 (+)NCBI
mRatBN7.2252,498,299 - 52,508,409 (+)NCBI
Rnor_6.0253,106,088 - 53,116,198 (+)NCBI
Rnor_5.0272,138,104 - 72,148,390 (+)NCBI
RGSC_v3.4252,451,883 - 52,462,263 (+)RGD
Celera248,213,052 - 48,223,163 (+)NCBI
Sequence:
RefSeq Acc Id: NP_062065   ⟸   NM_019192
- Peptide Label: precursor
- UniProtKB: P25236 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001077380   ⟸   NM_001083911
- Peptide Label: precursor
- UniProtKB: P25236 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069020   ⟸   ENSRNOT00000086590
Protein Domains
Selenoprotein P N-terminal

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3660 AgrOrtholog
BioCyc Gene G2FUF-54208 BioCyc
Ensembl Genes ENSRNOG00000053086 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000086590 ENTREZGENE
  ENSRNOT00000086590.2 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6890056 IMAGE-MGC_LOAD
  IMAGE:7104195 IMAGE-MGC_LOAD
InterPro Selenoprotein-P_N UniProtKB/Swiss-Prot
  SelP_C UniProtKB/Swiss-Prot
  SeP UniProtKB/Swiss-Prot
KEGG Report rno:29360 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72854 IMAGE-MGC_LOAD
  MGC:91714 IMAGE-MGC_LOAD
NCBI Gene 29360 ENTREZGENE
PANTHER PTHR10105 UniProtKB/Swiss-Prot
  SELENOPROTEIN P UniProtKB/Swiss-Prot
Pfam SelP_C UniProtKB/Swiss-Prot
  SelP_N UniProtKB/Swiss-Prot
PhenoGen Selenop PhenoGen
RatGTEx ENSRNOG00000053086 RatGTEx
UniProt A0A0G2JU99_RAT UniProtKB/TrEMBL
  P25236 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-09-28 Selenop  selenoprotein P  Sepp1  selenoprotein P, plasma, 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Sepp1  selenoprotein P, plasma, 1       Name updated 70584 APPROVED