(+)-taxifolin multiple interactions EXP 6480464 Fluvastatin promotes the reaction [taxifolin inhibits the reaction [bisphenol A results in increased expression of IL18 protein]] more ... CTD PMID:35465754 (1->4)-beta-D-glucan multiple interactions ISO Il18 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of IL18 mRNA CTD PMID:36331819 (4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid multiple interactions ISO Il18 (Mus musculus) 6480464 zopolrestat inhibits the reaction [Antigens and Plant results in increased expression of IL18 mRNA] CTD PMID:21334316 (E)-cinnamyl alcohol increases expression ISO IL18 (Homo sapiens) 6480464 cinnamyl alcohol results in increased expression of IL18 protein CTD PMID:23063874 (S)-nicotine increases secretion ISO IL18 (Homo sapiens) 6480464 Nicotine results in increased secretion of IL18 protein CTD PMID:35131329 (S)-nicotine multiple interactions ISO IL18 (Homo sapiens) 6480464 CHRNA5 protein affects the reaction [Nicotine results in increased secretion of IL18 protein] CTD PMID:35131329 (S)-ropivacaine increases expression ISO IL18 (Homo sapiens) 6480464 Ropivacaine results in increased expression of IL18 protein CTD PMID:36858639 (S)-ropivacaine multiple interactions ISO IL18 (Homo sapiens) 6480464 Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL18 protein] more ... CTD PMID:36858639 1,2-dichloroethane decreases expression ISO Il18 (Mus musculus) 6480464 ethylene dichloride results in decreased expression of IL18 mRNA CTD PMID:28189721 and PMID:28960355 1,2-dichloroethane multiple interactions ISO Il18 (Mus musculus) 6480464 [ethylene dichloride co-treated with Ethanol] results in increased expression of IL18 protein and allyl sulfide inhibits the reaction [[ethylene dichloride co-treated with Ethanol] results in increased expression of IL18 protein] CTD PMID:37150348 1,2-dimethylhydrazine multiple interactions ISO Il18 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of IL18 mRNA CTD PMID:22206623 1,2-dimethylhydrazine decreases expression ISO Il18 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of IL18 mRNA CTD PMID:22206623 1,3-benzothiazole-2-thiol increases expression ISO IL18 (Homo sapiens) 6480464 captax results in increased expression of IL18 protein CTD PMID:23063874 1,4-phenylenediamine increases expression ISO IL18 (Homo sapiens) 6480464 4-phenylenediamine results in increased expression of IL18 protein CTD PMID:23063874 and PMID:27585668 1,4-phenylenediamine multiple interactions ISO IL18 (Homo sapiens) 6480464 PRDM1 protein promotes the reaction [4-phenylenediamine results in increased expression of IL18 protein] CTD PMID:27585668 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine multiple interactions ISO Il18 (Mus musculus) 6480464 Trimetazidine inhibits the reaction [Folic Acid results in increased expression of IL18 protein] CTD PMID:35191561 1-chloro-2,4,6-trinitrobenzene multiple interactions ISO IL18 (Homo sapiens) 6480464 CASP1 protein promotes the reaction [Picryl Chloride results in increased cleavage of IL18 protein] CTD PMID:17429439 1-chloro-2,4,6-trinitrobenzene increases secretion ISO Il18 (Mus musculus) 6480464 Picryl Chloride results in increased secretion of IL18 protein CTD PMID:20381601 1-chloro-2,4,6-trinitrobenzene increases expression ISO Il18 (Mus musculus) 6480464 Picryl Chloride results in increased expression of IL18 mRNA and Picryl Chloride results in increased expression of IL18 protein CTD PMID:15734285 more ... 1-chloro-2,4,6-trinitrobenzene multiple interactions ISO Il18 (Mus musculus) 6480464 Cyclosporine inhibits the reaction [Picryl Chloride results in increased expression of IL18 protein] more ... CTD PMID:16442096 and PMID:20381601 1-chloro-2,4,6-trinitrobenzene increases cleavage ISO IL18 (Homo sapiens) 6480464 Picryl Chloride results in increased cleavage of IL18 protein CTD PMID:17429439 1-chloro-2,4-dinitrobenzene increases activity ISO Il18 (Mus musculus) 6480464 Dinitrochlorobenzene results in increased activity of IL18 protein CTD PMID:15840424 1-chloro-2,4-dinitrobenzene multiple interactions ISO IL18 (Homo sapiens) 6480464 PRDM1 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of IL18 protein] CTD PMID:27585668 1-chloro-2,4-dinitrobenzene increases expression ISO IL18 (Homo sapiens) 6480464 Dinitrochlorobenzene results in increased expression of IL18 protein CTD PMID:23063874 more ... 1-chloro-2,4-dinitrobenzene increases expression ISO Il18 (Mus musculus) 6480464 Dinitrochlorobenzene results in increased expression of IL18 mRNA CTD PMID:11708898 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of IL18 mRNA CTD PMID:12075121 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of IL18 mRNA CTD PMID:15576828 and PMID:17351261 17beta-estradiol affects expression ISO IL18 (Homo sapiens) 6480464 Estradiol affects the expression of IL18 mRNA CTD PMID:22574217 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of IL18 mRNA CTD PMID:35192832 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of IL18 mRNA CTD PMID:32145629 17beta-estradiol increases expression ISO IL18 (Homo sapiens) 6480464 Estradiol results in increased expression of IL18 mRNA CTD PMID:23373633 and PMID:25878060 17beta-estradiol decreases expression ISO IL18 (Homo sapiens) 6480464 Estradiol results in decreased expression of IL18 mRNA CTD PMID:25878060 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO IL18 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of IL18 mRNA CTD PMID:16039398 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of IL18 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Il18 (Mus musculus) 6480464 KL protein inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [lipopolysaccharide more ... CTD PMID:29885354 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of IL18 mRNA CTD PMID:20959002 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Il18 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of IL18 mRNA CTD PMID:12167310 and PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of IL18 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO IL18 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of IL18 mRNA CTD PMID:22298810 2,4,6-trinitrobenzenesulfonic acid increases expression ISO Il18 (Mus musculus) 6480464 Trinitrobenzenesulfonic Acid results in increased expression of IL18 mRNA CTD PMID:15973123 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP 6480464 bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL18 protein] CTD PMID:30365937 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of IL18 protein CTD PMID:30365937 2,4-D increases expression EXP 6480464 2 more ... CTD PMID:34464015 2,4-D increases expression ISO Il18 (Mus musculus) 6480464 2 more ... CTD PMID:35099110 2,4-D multiple interactions ISO Il18 (Mus musculus) 6480464 lycium barbarum polysaccharide inhibits the reaction [2 more ... CTD PMID:35099110 2,4-D multiple interactions EXP 6480464 lycium barbarum polysaccharide inhibits the reaction [2 more ... CTD PMID:34464015 2-amino-2-deoxy-D-galactopyranose increases expression ISO Il18 (Mus musculus) 6480464 Galactosamine results in increased expression of IL18 mRNA and Galactosamine results in increased expression of IL18 protein CTD PMID:20102673 2-amino-2-deoxy-D-galactopyranose increases expression EXP 6480464 Galactosamine results in increased expression of IL18 mRNA CTD PMID:22310181 2-amino-2-deoxy-D-galactopyranose multiple interactions EXP 6480464 mangiferin inhibits the reaction [Galactosamine results in increased expression of IL18 mRNA] CTD PMID:22310181 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO Il18 (Mus musculus) 6480464 [LEP gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL18 mRNA more ... CTD PMID:19913045 and PMID:20102673 2-bromo-2-(bromomethyl)pentanedinitrile increases expression ISO IL18 (Homo sapiens) 6480464 1 more ... CTD PMID:23063874 2-hydroxypropanoic acid decreases expression ISO IL18 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of IL18 mRNA CTD PMID:30851411 2-palmitoylglycerol increases expression ISO IL18 (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of IL18 mRNA CTD PMID:37199045 3,3',4,4',5-pentachlorobiphenyl affects expression ISO IL18 (Homo sapiens) 6480464 3 more ... CTD PMID:21703328 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of IL18 mRNA CTD PMID:28300664 3-chloropropane-1,2-diol decreases expression EXP 6480464 alpha-Chlorohydrin results in decreased expression of IL18 mRNA CTD PMID:28522335 3-methyladenine multiple interactions ISO IL18 (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [Patulin results in increased expression of IL18 protein] and 3-methyladenine promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] CTD PMID:30205151 and PMID:33217525 3-methyladenine multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [sphingosine 1-phosphate results in increased expression of IL18 protein] CTD PMID:37169277 3-methylcholanthrene increases expression ISO IL18 (Homo sapiens) 6480464 Methylcholanthrene results in increased expression of IL18 mRNA CTD PMID:14993811 3-Nitrobenzanthrone decreases expression ISO IL18 (Homo sapiens) 6480464 3-nitrobenzanthrone results in decreased expression of IL18 mRNA CTD PMID:34036453 3-phenylprop-2-enal increases expression ISO IL18 (Homo sapiens) 6480464 cinnamaldehyde results in increased expression of IL18 mRNA and cinnamaldehyde results in increased expression of IL18 protein CTD PMID:23063874 and PMID:30806763 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1 and 2-dithiol-3-thione results in decreased expression of IL18 mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane decreases expression ISO Il18 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of IL18 mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol decreases methylation ISO IL18 (Homo sapiens) 6480464 bisphenol S results in decreased methylation of IL18 gene CTD PMID:31601247 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression ISO IL18 (Homo sapiens) 6480464 Oxazolone results in increased expression of IL18 protein CTD PMID:23063874 4-hydroxynon-2-enal decreases expression ISO Il18 (Mus musculus) 6480464 4-hydroxy-2-nonenal results in decreased expression of IL18 mRNA CTD PMID:19191707 4-hydroxynon-2-enal decreases expression ISO IL18 (Homo sapiens) 6480464 4-hydroxy-2-nonenal results in decreased expression of IL18 mRNA CTD PMID:12419474 4-hydroxyphenyl retinamide decreases expression ISO Il18 (Mus musculus) 6480464 Fenretinide results in decreased expression of IL18 mRNA CTD PMID:28973697 4-methylhistamine multiple interactions ISO IL18 (Homo sapiens) 6480464 4-methylhistamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein] more ... CTD PMID:11752121 and PMID:12364868 4-nitrobenzyl bromide increases expression ISO IL18 (Homo sapiens) 6480464 4-nitrobenzyl bromide results in increased expression of IL18 protein CTD PMID:23063874 4-phenylbutyric acid multiple interactions ISO Il18 (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of IL18 mRNA] CTD PMID:30796460 4-phenylbutyric acid multiple interactions ISO IL18 (Homo sapiens) 6480464 4-phenylbutyric acid inhibits the reaction [7 more ... CTD PMID:35297523 and PMID:36646296 5-fluorouracil multiple interactions ISO IL18 (Homo sapiens) 6480464 [Fluorouracil co-treated with irinotecan] results in decreased expression of IL18 mRNA more ... CTD PMID:15162350 and PMID:16391804 5-fluorouracil affects expression ISO Il18 (Mus musculus) 6480464 Fluorouracil affects the expression of IL18 mRNA CTD PMID:20421339 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of IL18 mRNA CTD PMID:37047793 7,12-dimethyltetraphene multiple interactions ISO Il18 (Mus musculus) 6480464 dieckol inhibits the reaction [9 more ... CTD PMID:33347706 7,12-dimethyltetraphene increases expression ISO Il18 (Mus musculus) 6480464 9 more ... CTD PMID:33347706 8-Br-cAMP increases expression ISO IL18 (Homo sapiens) 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IL18 mRNA CTD PMID:22079614 8-chloro-2'-deoxyguanosine increases expression ISO Il18 (Mus musculus) 6480464 8-chloro-2'-deoxyguanosine results in increased expression of IL18 mRNA CTD PMID:31066272 acetamide increases expression EXP 6480464 acetamide results in increased expression of IL18 mRNA CTD PMID:31881176 acetic acid multiple interactions EXP 6480464 Plant Extracts inhibits the reaction [Acetic Acid results in increased expression of IL18 protein] and Sulfasalazine inhibits the reaction [Acetic Acid results in increased expression of IL18 protein] CTD PMID:35595039 acetic acid increases expression EXP 6480464 Acetic Acid results in increased expression of IL18 protein CTD PMID:35595039 acetylsalicylic acid multiple interactions ISO Il18 (Mus musculus) 6480464 Aspirin inhibits the reaction [Acetaminophen results in increased expression of IL18 mRNA] CTD PMID:19164858 acetylsalicylic acid affects response to substance ISO IL18 (Homo sapiens) 6480464 IL18 polymorphism affects the susceptibility to Aspirin CTD PMID:21692767 aconitine increases expression ISO Il18 (Mus musculus) 6480464 Aconitine results in increased expression of IL18 protein CTD PMID:33236894 aconitine multiple interactions EXP 6480464 NLRP3 protein affects the reaction [Aconitine results in increased expression of IL18 protein] more ... CTD PMID:33236894 aconitine increases expression EXP 6480464 Aconitine results in increased expression of IL18 protein CTD PMID:33236894 acrolein multiple interactions ISO IL18 (Homo sapiens) 6480464 3-methyladenine promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] more ... CTD PMID:30205151 and PMID:36055550 acrolein increases expression ISO IL18 (Homo sapiens) 6480464 Acrolein results in increased expression of IL18 protein CTD PMID:36055550 acrylamide multiple interactions ISO Il18 (Mus musculus) 6480464 N-(1 more ... CTD PMID:31073625 and PMID:32014472 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of IL18 mRNA and Acrylamide results in increased expression of IL18 protein CTD PMID:31073625 acrylamide increases expression ISO Il18 (Mus musculus) 6480464 Acrylamide results in increased expression of IL18 mRNA and Acrylamide results in increased expression of IL18 protein CTD PMID:31073625 and PMID:32014472 aflatoxin B1 affects expression ISO IL18 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of IL18 protein CTD PMID:20106945 aflatoxin B1 decreases expression ISO Il18 (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of IL18 mRNA CTD PMID:36603704 aflatoxin B1 increases expression ISO Il18 (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of IL18 mRNA CTD PMID:35063475 aflatoxin B1 multiple interactions ISO Il18 (Mus musculus) 6480464 Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of IL18 mRNA] and Curcumin inhibits the reaction [Aflatoxin B1 results in increased secretion of IL18 protein] CTD PMID:35063475 aflatoxin B1 increases secretion ISO Il18 (Mus musculus) 6480464 Aflatoxin B1 results in increased secretion of IL18 protein CTD PMID:35063475 aflatoxin B1 decreases methylation ISO IL18 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of IL18 gene CTD PMID:27153756 aldehydo-D-glucose increases expression ISO IL18 (Homo sapiens) 6480464 Glucose results in increased expression of IL18 mRNA and Glucose results in increased expression of IL18 protein CTD PMID:36066211 and PMID:37473909 aldehydo-D-glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL18 protein and diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL18 protein] CTD PMID:35191607 aldehydo-D-glucose multiple interactions ISO IL18 (Homo sapiens) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased secretion of IL18 protein more ... CTD PMID:35607288 more ... aldehydo-D-glucose increases secretion ISO IL18 (Homo sapiens) 6480464 Glucose results in increased secretion of IL18 protein CTD PMID:35607288 aldehydo-D-glucose increases secretion ISO Il18 (Mus musculus) 6480464 Glucose results in increased secretion of IL18 protein CTD PMID:34212273 aldehydo-D-glucose multiple interactions ISO Il18 (Mus musculus) 6480464 GSDMD protein affects the reaction [Glucose results in increased secretion of IL18 protein] and Hirudins inhibits the reaction [Glucose results in increased secretion of IL18 protein] CTD PMID:34212273 aldehydo-D-glucose increases expression ISO Il18 (Mus musculus) 6480464 Glucose results in increased expression of IL18 mRNA CTD PMID:34212273 aldosterone increases expression EXP 6480464 Aldosterone results in increased expression of IL18 mRNA and Aldosterone results in increased expression of IL18 protein CTD PMID:18660453 aldosterone multiple interactions EXP 6480464 [cyclo(Trp-Asp-Pro-Val-Leu) binds to and results in decreased activity of EDNRA protein] inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] more ... CTD PMID:18660453 alendronic acid multiple interactions ISO Il18 (Mus musculus) 6480464 [Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide more ... CTD PMID:21430599 all-trans-retinoic acid affects expression ISO Il18 (Mus musculus) 6480464 Tretinoin affects the expression of IL18 mRNA CTD PMID:20421339 allopurinol multiple interactions EXP 6480464 Allopurinol inhibits the reaction [Fructose results in increased expression of IL18 protein] and Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL18 protein] CTD PMID:22426011 and PMID:23647015 aluminium sulfate (anhydrous) increases expression ISO IL18 (Homo sapiens) 6480464 aluminum sulfate results in increased expression of IL18 protein CTD PMID:16100009 amiodarone multiple interactions ISO Il18 (Mus musculus) 6480464 Amiodarone promotes the reaction [Dexamethasone results in decreased expression of IL18 mRNA] CTD PMID:25900201 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of IL18 mRNA CTD PMID:16483693 amphibole asbestos increases expression ISO IL18 (Homo sapiens) 6480464 Asbestos and Amphibole results in increased expression of IL18 protein CTD PMID:20855422 amphibole asbestos increases expression EXP 6480464 Asbestos and Amphibole results in increased expression of IL18 mRNA CTD PMID:27083413 ampicillin multiple interactions ISO Il18 (Mus musculus) 6480464 [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased secretion of IL18 protein] CTD PMID:35390362 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO IL18 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [[Lipopolysaccharides co-treated with irinotecan] results in increased expression of and results in increased secretion of IL18 protein] CTD PMID:26431797 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO Il18 (Mus musculus) 6480464 pyrazolanthrone inhibits the reaction [Benzo(a)pyrene results in increased secretion of IL18 protein] more ... CTD PMID:20381601 more ... anthranilic acid multiple interactions ISO IL18 (Homo sapiens) 6480464 anthranilic acid analog inhibits the reaction [IL18 protein results in increased secretion of IFNG protein] CTD PMID:15799959 antirheumatic drug decreases expression ISO IL18 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of IL18 mRNA CTD PMID:24449571 apocynin multiple interactions ISO Il18 (Mus musculus) 6480464 acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL18 mRNA] CTD PMID:28539244 Aroclor 1254 decreases expression ISO IL18 (Homo sapiens) 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of IL18 mRNA CTD PMID:17851650 arsenite(3-) decreases expression ISO IL18 (Homo sapiens) 6480464 arsenite results in decreased expression of IL18 mRNA CTD PMID:16085347 arsenite(3-) multiple interactions ISO IL18 (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to IL18 mRNA] and caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL18 mRNA] CTD PMID:16085347 and PMID:32406909 arsenous acid decreases expression ISO Il18 (Mus musculus) 6480464 Arsenic Trioxide results in decreased expression of IL18 CTD PMID:20693187 arsenous acid increases secretion ISO Il18 (Mus musculus) 6480464 Arsenic Trioxide results in increased secretion of IL18 protein CTD PMID:35226250 arsenous acid increases secretion ISO IL18 (Homo sapiens) 6480464 Arsenic Trioxide results in increased secretion of IL18 protein CTD PMID:35226250 arsenous acid multiple interactions ISO IL18 (Homo sapiens) 6480464 IGF2BP2 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL18 protein] and METTL14 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL18 protein] CTD PMID:35226250 asperentin increases expression ISO Il18 (Mus musculus) 6480464 cladosporin results in increased expression of IL18 mRNA CTD PMID:19818335 atorvastatin calcium multiple interactions ISO Il18 (Mus musculus) 6480464 Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL18 protein] CTD PMID:37023836 ATP multiple interactions ISO IL18 (Homo sapiens) 6480464 [Adenosine Triphosphate co-treated with K-12 lipopolysaccharide] results in increased secretion of IL18 protein more ... CTD PMID:17404311 more ... ATP multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein more ... CTD PMID:35962723 ATP increases secretion ISO Il18 (Mus musculus) 6480464 Adenosine Triphosphate results in increased secretion of IL18 protein CTD PMID:27311643 ATP multiple interactions ISO Il18 (Mus musculus) 6480464 3-(5-(2 more ... CTD PMID:26431797 more ... atrazine decreases expression ISO IL18 (Homo sapiens) 6480464 Atrazine results in decreased expression of IL18 mRNA CTD PMID:22378314 aucubin multiple interactions ISO Il18 (Mus musculus) 6480464 aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 protein] CTD PMID:35961541 aurantio-obtusin increases expression ISO Il18 (Mus musculus) 6480464 aurantio-obtusin results in increased expression of IL18 mRNA and aurantio-obtusin results in increased expression of IL18 protein CTD PMID:34718095 bellidifolin multiple interactions ISO IL18 (Homo sapiens) 6480464 bellidifolin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased secretion of IL18 protein] CTD PMID:37127800 Belnacasan multiple interactions ISO IL18 (Homo sapiens) 6480464 belnacasan inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] CTD PMID:30205151 Belnacasan multiple interactions ISO Il18 (Mus musculus) 6480464 belnacasan inhibits the reaction [Toluene 2 and 4-Diisocyanate results in increased expression of IL18 protein] CTD PMID:31070765 benzalkonium chloride increases expression ISO Il18 (Mus musculus) 6480464 Benzalkonium Compounds results in increased expression of IL18 protein CTD PMID:30517752 benzalkonium chloride increases expression ISO IL18 (Homo sapiens) 6480464 Benzalkonium Compounds results in increased expression of IL18 mRNA CTD PMID:30806763 benzo[a]pyrene increases expression ISO IL18 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of IL18 mRNA and Benzo(a)pyrene results in increased expression of IL18 protein CTD PMID:21632981 more ... benzo[a]pyrene increases secretion ISO Il18 (Mus musculus) 6480464 Benzo(a)pyrene results in increased secretion of IL18 protein CTD PMID:35777681 benzo[a]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with Dibutyl Phthalate] results in increased expression of IL18 mRNA more ... CTD PMID:34999049 and PMID:36592837 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of IL18 mRNA CTD PMID:34999049 benzo[a]pyrene affects methylation ISO IL18 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of IL18 promoter CTD PMID:27901495 benzo[a]pyrene decreases methylation ISO IL18 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of IL18 5' UTR CTD PMID:27901495 benzo[a]pyrene multiple interactions ISO IL18 (Homo sapiens) 6480464 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Benzo(a)pyrene] results in increased expression of IL18 protein and IGF1 protein inhibits the reaction [Benzo(a)pyrene results in increased expression of IL18 protein] CTD PMID:30726812 benzo[a]pyrene multiple interactions ISO Il18 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased secretion of IL18 protein] more ... CTD PMID:22228805 and PMID:35777681 benzo[a]pyrene diol epoxide I multiple interactions ISO IL18 (Homo sapiens) 6480464 4-phenylbutyric acid inhibits the reaction [7 more ... CTD PMID:35297523 benzocaine increases activity ISO Il18 (Mus musculus) 6480464 Benzocaine results in increased activity of IL18 protein CTD PMID:15840424 benzylpenicillin increases expression ISO IL18 (Homo sapiens) 6480464 Penicillin G results in increased expression of IL18 protein CTD PMID:23063874 Bergenin multiple interactions EXP 6480464 bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL18 protein] CTD PMID:30365937 beryllium sulfate increases expression ISO IL18 (Homo sapiens) 6480464 beryllium sulfate results in increased expression of IL18 mRNA and beryllium sulfate results in increased expression of IL18 protein CTD PMID:16100009 beta-cyclodextrin multiple interactions ISO Il18 (Mus musculus) 6480464 [myelin oligodendrocyte glycoprotein (35-55) co-treated with Freund's Adjuvant co-treated with Pertussis Toxin co-treated with betadex] results in increased expression of IL18 protein and lonidamine inhibits the reaction [[myelin oligodendrocyte glycoprotein (35-55) co-treated with Freund's Adjuvant co-treated with Pertussis Toxin co-treated with betadex] results in increased expression of IL18 protein] CTD PMID:36577999 bexarotene decreases expression EXP 6480464 bexarotene results in decreased expression of IL18 mRNA CTD PMID:16648578 bezafibrate multiple interactions EXP 6480464 Bezafibrate inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 bilirubin IXalpha multiple interactions ISO IL18 (Homo sapiens) 6480464 Bilirubin inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein] and Bilirubin inhibits the reaction [IL18 protein results in increased expression of PTEN protein] CTD PMID:18215737 bilirubin IXalpha decreases response to substance ISO IL18 (Homo sapiens) 6480464 Bilirubin results in decreased susceptibility to IL18 protein CTD PMID:18215737 biliverdin multiple interactions ISO IL18 (Homo sapiens) 6480464 Biliverdine inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein] and Biliverdine inhibits the reaction [IL18 protein results in increased expression of PTEN protein] CTD PMID:18215737 biliverdin decreases response to substance ISO IL18 (Homo sapiens) 6480464 Biliverdine results in decreased susceptibility to IL18 protein CTD PMID:18215737 bis(2-chloroethyl) sulfide decreases expression ISO Il18 (Mus musculus) 6480464 Mustard Gas results in decreased expression of IL18 mRNA CTD PMID:18955075 bis(2-ethylhexyl) phthalate multiple interactions ISO Il18 (Mus musculus) 6480464 Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL18 protein] CTD PMID:36610486 bis(2-ethylhexyl) phthalate increases expression ISO Il18 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of IL18 protein CTD PMID:36610486 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of IL18 mRNA CTD PMID:12075121 bisphenol A multiple interactions ISO IL18 (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [bisphenol A affects the expression of IL18 mRNA] CTD PMID:35439536 bisphenol A decreases methylation ISO IL18 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of IL18 gene CTD PMID:31601247 bisphenol A increases expression ISO Il18 (Mus musculus) 6480464 bisphenol A results in increased expression of IL18 mRNA and bisphenol A results in increased expression of IL18 protein CTD PMID:32540565 bisphenol A multiple interactions EXP 6480464 Fluvastatin inhibits the reaction [bisphenol A results in increased expression of IL18 protein] more ... CTD PMID:28285737 and PMID:35465754 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of IL18 mRNA and bisphenol A results in increased expression of IL18 protein CTD PMID:28285737 more ... bisphenol A decreases expression ISO Il18 (Mus musculus) 6480464 bisphenol A results in decreased expression of IL18 mRNA CTD PMID:26063408 bisphenol A increases secretion ISO IL18 (Homo sapiens) 6480464 bisphenol A results in increased secretion of IL18 protein CTD PMID:25878060 bisphenol A increases expression ISO IL18 (Homo sapiens) 6480464 bisphenol A results in increased expression of IL18 mRNA CTD PMID:25878060 and PMID:35439536 bisphenol F decreases expression ISO Il18 (Mus musculus) 6480464 bisphenol F results in decreased expression of IL18 mRNA CTD PMID:30951980 boric acid multiple interactions EXP 6480464 [boric acid results in increased abundance of Boron] inhibits the reaction [Acetaminophen results in increased expression of IL18 protein] CTD PMID:35020164 boron atom multiple interactions EXP 6480464 [boric acid results in increased abundance of Boron] inhibits the reaction [Acetaminophen results in increased expression of IL18 protein] CTD PMID:35020164 BQ 123 multiple interactions EXP 6480464 [cyclo(Trp-Asp-Pro-Val-Leu) binds to and results in decreased activity of EDNRA protein] inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 Brevianamide A increases expression ISO Il18 (Mus musculus) 6480464 brevianamide A results in increased expression of IL18 mRNA CTD PMID:19818335 butyric acid increases expression ISO IL18 (Homo sapiens) 6480464 Butyric Acid results in increased expression of IL18 mRNA CTD PMID:17928716 cadmium atom increases expression ISO IL18 (Homo sapiens) 6480464 Cadmium results in increased expression of IL18 mRNA CTD PMID:33559965 cadmium atom multiple interactions ISO Il18 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL18 mRNA CTD PMID:33359024 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL18 mRNA CTD PMID:34510229 cadmium atom multiple interactions ISO IL18 (Homo sapiens) 6480464 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2 more ... CTD PMID:34510229 and PMID:37300869 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of IL18 protein CTD PMID:28759707 cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL18 mRNA CTD PMID:34510229 cadmium dichloride multiple interactions ISO Il18 (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of IL18 mRNA] and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL18 mRNA CTD PMID:30796460 and PMID:33359024 cadmium dichloride multiple interactions ISO IL18 (Homo sapiens) 6480464 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2 more ... CTD PMID:30796460 more ... cadmium dichloride increases secretion ISO IL18 (Homo sapiens) 6480464 Cadmium Chloride results in increased secretion of IL18 protein CTD PMID:30796460 cadmium dichloride increases expression ISO IL18 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of IL18 mRNA CTD PMID:30796460 cannabidiol decreases expression ISO IL18 (Homo sapiens) 6480464 Cannabidiol results in decreased expression of IL18 mRNA and Cannabidiol results in decreased expression of IL18 protein CTD PMID:27932991 and PMID:34269108 cannabidiol decreases expression ISO Il18 (Mus musculus) 6480464 Cannabidiol results in decreased expression of IL18 protein CTD PMID:34269108 cannabidiol multiple interactions ISO IL18 (Homo sapiens) 6480464 iodopravadoline inhibits the reaction [Cannabidiol results in decreased expression of IL18 protein] and Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of IL18 protein] CTD PMID:27932991 carbon monoxide decreases response to substance ISO IL18 (Homo sapiens) 6480464 Carbon Monoxide results in decreased susceptibility to IL18 protein CTD PMID:18215737 carbon monoxide multiple interactions ISO IL18 (Homo sapiens) 6480464 Carbon Monoxide inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein] and Carbon Monoxide inhibits the reaction [IL18 protein results in increased expression of PTEN protein] CTD PMID:18215737 carbon nanotube decreases expression ISO Il18 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 carbon nanotube increases secretion ISO Il18 (Mus musculus) 6480464 Nanotubes and Carbon results in increased secretion of IL18 protein CTD PMID:19371758 carbonyl cyanide p-trifluoromethoxyphenylhydrazone decreases expression ISO IL18 (Homo sapiens) 6480464 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of IL18 mRNA CTD PMID:16039398 cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of IL18 mRNA CTD PMID:18500788 celastrol multiple interactions EXP 6480464 celastrol inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein] more ... CTD PMID:32470352 cerium trichloride increases expression ISO Il18 (Mus musculus) 6480464 cerous chloride results in increased expression of IL18 CTD PMID:23712967 chloroethene decreases expression ISO Il18 (Mus musculus) 6480464 Vinyl Chloride results in decreased expression of IL18 mRNA CTD PMID:34717031 chloropicrin increases expression ISO IL18 (Homo sapiens) 6480464 chloropicrin results in increased expression of IL18 mRNA CTD PMID:26352163 chloroquine multiple interactions ISO IL18 (Homo sapiens) 6480464 Chloroquine promotes the reaction [[lipopolysaccharide and Escherichia coli O111 B4 co-treated with sodium arsenite] results in increased expression of IL18 protein] CTD PMID:34920032 chlorpyrifos multiple interactions ISO IL18 (Homo sapiens) 6480464 NFE2L2 protein inhibits the reaction [Chlorpyrifos results in increased expression of IL18 mRNA] and NFE2L2 protein inhibits the reaction [Chlorpyrifos results in increased expression of IL18 protein] CTD PMID:30835941 chlorpyrifos increases expression ISO IL18 (Homo sapiens) 6480464 Chlorpyrifos results in increased expression of IL18 mRNA and Chlorpyrifos results in increased expression of IL18 protein CTD PMID:30835941 choline increases methylation ISO IL18 (Homo sapiens) 6480464 Choline results in increased methylation of IL18 gene CTD PMID:30116142 choline multiple interactions ISO Il18 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL18 mRNA more ... CTD PMID:37023836 cimetidine multiple interactions ISO IL18 (Homo sapiens) 6480464 CASP1 protein affects the reaction [Cimetidine results in increased expression of IL18 protein] more ... CTD PMID:16723495 cimetidine multiple interactions ISO Il18 (Mus musculus) 6480464 HRH2 protein affects the reaction [Cimetidine results in increased expression of IL18 protein] CTD PMID:16723495 cimetidine increases expression ISO Il18 (Mus musculus) 6480464 Cimetidine results in increased expression of IL18 protein CTD PMID:16723495 cimetidine increases expression ISO IL18 (Homo sapiens) 6480464 Cimetidine results in increased expression of IL18 protein CTD PMID:16723495 cinnamyl alcohol increases expression ISO IL18 (Homo sapiens) 6480464 cinnamyl alcohol results in increased expression of IL18 protein CTD PMID:23063874 cisplatin decreases expression ISO IL18 (Homo sapiens) 6480464 Cisplatin results in decreased expression of IL18 CTD PMID:17021654 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of IL18 protein CTD PMID:29216766 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of IL18 mRNA CTD PMID:35842499 cisplatin multiple interactions EXP 6480464 vanillin inhibits the reaction [Cisplatin results in increased expression of IL18 protein] CTD PMID:29216766 cisplatin increases expression ISO IL18 (Homo sapiens) 6480464 Cisplatin results in increased expression of IL18 mRNA CTD PMID:27594783 cisplatin multiple interactions ISO IL18 (Homo sapiens) 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of IL18 mRNA CTD PMID:20705681 cisplatin increases expression ISO Il18 (Mus musculus) 6480464 Cisplatin results in increased expression of IL18 mRNA and Cisplatin results in increased expression of IL18 protein CTD PMID:21151649 more ... citral increases expression ISO IL18 (Homo sapiens) 6480464 citral results in increased expression of IL18 protein CTD PMID:23063874 clenbuterol increases expression ISO Il18 (Mus musculus) 6480464 Clenbuterol results in increased expression of IL18 mRNA and Clenbuterol results in increased expression of IL18 protein CTD PMID:15178407 clofibrate decreases expression ISO Il18 (Mus musculus) 6480464 Clofibrate results in decreased expression of IL18 mRNA CTD PMID:17585979 cobalt atom multiple interactions ISO Il18 (Mus musculus) 6480464 [Cobalt co-treated with Organometallic Compounds] results in increased expression of IL18 mRNA CTD PMID:22147119 cobalt atom multiple interactions ISO IL18 (Homo sapiens) 6480464 NLRP3 protein promotes the reaction [Cobalt results in increased secretion of IL18 protein] CTD PMID:32805375 cobalt atom increases secretion ISO IL18 (Homo sapiens) 6480464 Cobalt results in increased secretion of IL18 protein CTD PMID:32805375 cobalt atom increases expression ISO Il18 (Mus musculus) 6480464 Cobalt results in increased expression of IL18 mRNA CTD PMID:22147119 cobalt atom multiple interactions EXP 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in decreased expression of IL18 mRNA CTD PMID:22198552 cobalt dichloride increases expression ISO IL18 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of IL18 mRNA CTD PMID:19376846 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of IL18 mRNA CTD PMID:24386269 copper(II) sulfate increases expression ISO IL18 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of IL18 mRNA CTD PMID:19549813 copper(II) sulfate increases secretion ISO Il18 (Mus musculus) 6480464 Copper Sulfate results in increased secretion of IL18 protein CTD PMID:37353053 copper(II) sulfate multiple interactions ISO Il18 (Mus musculus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased secretion of IL18 protein] CTD PMID:37353053 corn oil increases expression ISO Il18 (Mus musculus) 6480464 Corn Oil results in increased expression of IL18 mRNA CTD PMID:33263755 crocidolite asbestos increases secretion ISO IL18 (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased secretion of IL18 protein CTD PMID:23937860 and PMID:28056339 crocidolite asbestos multiple interactions ISO Il18 (Mus musculus) 6480464 CASP1 protein affects the reaction [Asbestos and Crocidolite results in increased expression of IL18 protein] CTD PMID:28056339 crocidolite asbestos increases expression ISO Il18 (Mus musculus) 6480464 Asbestos and Crocidolite results in increased expression of IL18 protein CTD PMID:28056339 crocidolite asbestos multiple interactions ISO IL18 (Homo sapiens) 6480464 IL1RN protein inhibits the reaction [Asbestos and Crocidolite results in increased secretion of IL18 protein] CTD PMID:28056339 crocidolite asbestos decreases expression ISO IL18 (Homo sapiens) 6480464 Asbestos and Crocidolite results in decreased expression of IL18 mRNA CTD PMID:24160326 and PMID:29523930 curcumin multiple interactions ISO IL18 (Homo sapiens) 6480464 Curcumin inhibits the reaction [IL18 protein results in increased expression of VEGFA mRNA] more ... CTD PMID:16368150 and PMID:17399992 curcumin multiple interactions ISO Il18 (Mus musculus) 6480464 Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of IL18 mRNA] and Curcumin inhibits the reaction [Aflatoxin B1 results in increased secretion of IL18 protein] CTD PMID:35063475 curcumin decreases expression ISO Il18 (Mus musculus) 6480464 Curcumin results in decreased expression of IL18 mRNA CTD PMID:16751071 curcumin decreases expression ISO IL18 (Homo sapiens) 6480464 Curcumin results in decreased expression of IL18 mRNA and Curcumin results in decreased expression of IL18 protein CTD PMID:17399992 Curcumol decreases expression ISO IL18 (Homo sapiens) 6480464 curcumol results in decreased expression of IL18 protein CTD PMID:32344006 cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 cyclophosphamide increases expression EXP 6480464 Cyclophosphamide results in increased expression of IL18 protein CTD PMID:18848347 cyclosporin A increases expression ISO IL18 (Homo sapiens) 6480464 Cyclosporine results in increased expression of IL18 mRNA CTD PMID:20106945 cyclosporin A decreases expression ISO IL18 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of IL18 mRNA CTD PMID:27989131 cyclosporin A multiple interactions ISO Il18 (Mus musculus) 6480464 Cyclosporine inhibits the reaction [Picryl Chloride results in increased expression of IL18 protein] CTD PMID:16442096 cypermethrin multiple interactions EXP 6480464 CXCL16 protein promotes the reaction [cypermethrin results in increased expression of IL18 mRNA] CTD PMID:35512476 cypermethrin increases expression EXP 6480464 cypermethrin results in increased expression of IL18 mRNA CTD PMID:35512476 D-glucose increases expression ISO IL18 (Homo sapiens) 6480464 Glucose results in increased expression of IL18 mRNA and Glucose results in increased expression of IL18 protein CTD PMID:36066211 and PMID:37473909 D-glucose increases secretion ISO IL18 (Homo sapiens) 6480464 Glucose results in increased secretion of IL18 protein CTD PMID:35607288 D-glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL18 protein and diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL18 protein] CTD PMID:35191607 D-glucose multiple interactions ISO IL18 (Homo sapiens) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased secretion of IL18 protein more ... CTD PMID:35607288 more ... D-glucose increases secretion ISO Il18 (Mus musculus) 6480464 Glucose results in increased secretion of IL18 protein CTD PMID:34212273 D-glucose increases expression ISO Il18 (Mus musculus) 6480464 Glucose results in increased expression of IL18 mRNA CTD PMID:34212273 D-glucose multiple interactions ISO Il18 (Mus musculus) 6480464 GSDMD protein affects the reaction [Glucose results in increased secretion of IL18 protein] and Hirudins inhibits the reaction [Glucose results in increased secretion of IL18 protein] CTD PMID:34212273 deoxynivalenol decreases expression ISO Il18 (Mus musculus) 6480464 deoxynivalenol results in decreased expression of IL18 mRNA CTD PMID:22968694 deoxynivalenol increases secretion ISO Il18 (Mus musculus) 6480464 deoxynivalenol results in increased secretion of IL18 protein CTD PMID:35925383 and PMID:36309173 deoxynivalenol increases expression ISO Il18 (Mus musculus) 6480464 deoxynivalenol results in increased expression of IL18 mRNA and deoxynivalenol results in increased expression of IL18 protein CTD PMID:35925383 and PMID:36309173 deoxynivalenol multiple interactions ISO Il18 (Mus musculus) 6480464 acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of IL18 mRNA] more ... CTD PMID:35925383 and PMID:36309173 dexamethasone multiple interactions ISO IL18 (Homo sapiens) 6480464 Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein] more ... CTD PMID:18951874 dexamethasone decreases expression ISO Il18 (Mus musculus) 6480464 Dexamethasone results in decreased expression of IL18 mRNA CTD PMID:25900201 dexamethasone multiple interactions ISO Il18 (Mus musculus) 6480464 Amiodarone promotes the reaction [Dexamethasone results in decreased expression of IL18 mRNA] and Dexamethasone inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein] CTD PMID:25448682 and PMID:25900201 dexamethasone increases expression ISO Il18 (Mus musculus) 6480464 Dexamethasone results in increased expression of IL18 mRNA CTD PMID:21041162 dexmedetomidine multiple interactions ISO IL18 (Homo sapiens) 6480464 Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL18 protein] more ... CTD PMID:36858639 dextran sulfate affects response to substance ISO Il18 (Mus musculus) 6480464 IL18 protein affects the susceptibility to Dextran Sulfate CTD PMID:12940437 dextran sulfate multiple interactions EXP 6480464 celastrol inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein] more ... CTD PMID:32470352 dextran sulfate increases secretion ISO Il18 (Mus musculus) 6480464 Dextran Sulfate results in increased secretion of IL18 protein CTD PMID:30270565 and PMID:37001609 dextran sulfate increases expression EXP 6480464 Dextran Sulfate results in increased expression of IL18 protein CTD PMID:32470352 dextran sulfate multiple interactions ISO Il18 (Mus musculus) 6480464 [Dextran Sulfate co-treated with Zearalenone] results in increased expression of IL18 mRNA more ... CTD PMID:25448682 more ... dextran sulfate increases expression ISO Il18 (Mus musculus) 6480464 Dextran Sulfate results in increased expression of IL18 mRNA and Dextran Sulfate results in increased expression of IL18 protein CTD PMID:25448682 and PMID:30270565 Diallyl sulfide multiple interactions ISO Il18 (Mus musculus) 6480464 allyl sulfide inhibits the reaction [[ethylene dichloride co-treated with Ethanol] results in increased expression of IL18 protein] CTD PMID:37150348 diarsenic trioxide decreases expression ISO Il18 (Mus musculus) 6480464 Arsenic Trioxide results in decreased expression of IL18 CTD PMID:20693187 diarsenic trioxide increases secretion ISO Il18 (Mus musculus) 6480464 Arsenic Trioxide results in increased secretion of IL18 protein CTD PMID:35226250 diarsenic trioxide multiple interactions ISO IL18 (Homo sapiens) 6480464 IGF2BP2 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL18 protein] and METTL14 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL18 protein] CTD PMID:35226250 diarsenic trioxide increases secretion ISO IL18 (Homo sapiens) 6480464 Arsenic Trioxide results in increased secretion of IL18 protein CTD PMID:35226250 dibenziodolium multiple interactions ISO IL18 (Homo sapiens) 6480464 diphenyleneiodonium inhibits the reaction [IL18 protein results in increased abundance of Reactive Oxygen Species] and diphenyleneiodonium inhibits the reaction [IL18 protein results in increased expression of BSG mRNA] CTD PMID:19561311 dibenziodolium multiple interactions ISO Il18 (Mus musculus) 6480464 diphenyleneiodonium inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein] and diphenyleneiodonium inhibits the reaction [Silicon Dioxide analog results in increased secretion of IL18 protein] CTD PMID:27311643 dibutyl phthalate multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with Dibutyl Phthalate] results in increased expression of IL18 mRNA and [Benzo(a)pyrene co-treated with Dibutyl Phthalate] results in increased expression of IL18 protein CTD PMID:36592837 dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of IL18 mRNA CTD PMID:18636392 dicrotophos decreases expression ISO IL18 (Homo sapiens) 6480464 dicrotophos results in decreased expression of IL18 mRNA CTD PMID:28302478 dieckol multiple interactions ISO Il18 (Mus musculus) 6480464 dieckol inhibits the reaction [9 more ... CTD PMID:33347706 dieldrin affects expression EXP 6480464 Dieldrin affects the expression of IL18 mRNA CTD PMID:22546817 diethyl malate affects expression ISO Il18 (Mus musculus) 6480464 diethyl malate affects the expression of IL18 mRNA CTD PMID:24814887 diethyl maleate increases expression ISO IL18 (Homo sapiens) 6480464 diethyl maleate results in increased expression of IL18 protein CTD PMID:23063874 diethyl phthalate increases expression ISO Il18 (Mus musculus) 6480464 diethyl phthalate results in increased expression of IL18 protein CTD PMID:37942807 diethylamine increases activity ISO Il18 (Mus musculus) 6480464 diethylamine results in increased activity of IL18 protein CTD PMID:15840424 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of IL18 mRNA CTD PMID:36653537 dihydroartemisinin multiple interactions ISO IL18 (Homo sapiens) 6480464 acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [artenimol results in increased secretion of IL18 protein] more ... CTD PMID:33689708 and PMID:34655567 dihydroartemisinin increases expression ISO IL18 (Homo sapiens) 6480464 artenimol results in increased expression of IL18 mRNA and artenimol results in increased expression of IL18 protein CTD PMID:33689708 dihydroartemisinin increases secretion ISO IL18 (Homo sapiens) 6480464 artenimol results in increased secretion of IL18 protein CTD PMID:33689708 and PMID:34655567 Dimaprit multiple interactions ISO IL18 (Homo sapiens) 6480464 Dimaprit inhibits the reaction [IL18 protein results in decreased expression of IL10 protein] more ... CTD PMID:11752121 and PMID:12364868 diosmetin multiple interactions EXP 6480464 diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL18 protein] and diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL18 protein] CTD PMID:35191607 dioxygen multiple interactions EXP 6480464 [dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of and results in increased secretion of IL18 protein] more ... CTD PMID:26464617 more ... dioxygen multiple interactions ISO IL18 (Homo sapiens) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased secretion of IL18 protein and bellidifolin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased secretion of IL18 protein] CTD PMID:37127800 disodium selenite multiple interactions EXP 6480464 Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IL18 mRNA] CTD PMID:28285737 disulfiram multiple interactions ISO IL18 (Homo sapiens) 6480464 [Disulfiram co-treated with Adenosine Triphosphate] inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein] and Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein] CTD PMID:33579316 and PMID:33851234 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of IL18 mRNA and Doxorubicin results in increased expression of IL18 protein CTD PMID:34343525 and PMID:35764897 doxorubicin multiple interactions EXP 6480464 geraniol inhibits the reaction [Doxorubicin results in increased expression of IL18 protein] more ... CTD PMID:34343525 and PMID:35764897 elemental boron multiple interactions EXP 6480464 [boric acid results in increased abundance of Boron] inhibits the reaction [Acetaminophen results in increased expression of IL18 protein] CTD PMID:35020164 emodin multiple interactions ISO Il18 (Mus musculus) 6480464 Emodin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL18 protein] CTD PMID:37023836 eplerenone multiple interactions EXP 6480464 eplerenone inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 epoxiconazole increases expression ISO Il18 (Mus musculus) 6480464 epoxiconazole results in increased expression of IL18 mRNA CTD PMID:35436446 ethanol affects response to substance ISO IL18 (Homo sapiens) 6480464 IL18 gene SNP affects the susceptibility to Ethanol CTD PMID:24349532 ethanol increases expression EXP 6480464 Ethanol results in increased expression of IL18 mRNA CTD PMID:34547370 ethanol affects expression ISO Il18 (Mus musculus) 6480464 Ethanol affects the expression of IL18 mRNA CTD PMID:30319688 ethanol multiple interactions ISO IL18 (Homo sapiens) 6480464 [Ethanol co-treated with Folic Acid] results in increased expression of IL18 mRNA more ... CTD PMID:23378141 more ... ethanol increases expression ISO IL18 (Homo sapiens) 6480464 Ethanol results in increased expression of IL18 mRNA and Ethanol results in increased expression of IL18 protein CTD PMID:28964808 and PMID:34474091 ethanol multiple interactions ISO Il18 (Mus musculus) 6480464 [ethylene dichloride co-treated with Ethanol] results in increased expression of IL18 protein more ... CTD PMID:28964808 and PMID:37150348 ethanol increases expression ISO Il18 (Mus musculus) 6480464 Ethanol results in increased expression of IL18 mRNA CTD PMID:28964808 eugenol increases expression ISO IL18 (Homo sapiens) 6480464 Eugenol results in increased expression of IL18 protein CTD PMID:23063874 famotidine multiple interactions ISO IL18 (Homo sapiens) 6480464 Famotidine inhibits the reaction [Cimetidine results in increased expression of IL18 protein] more ... CTD PMID:11752121 more ... fasudil multiple interactions EXP 6480464 fasudil inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 felodipine multiple interactions EXP 6480464 Felodipine inhibits the reaction [Fructose results in increased expression of IL18 mRNA] and Felodipine inhibits the reaction [Fructose results in increased expression of IL18 protein] CTD PMID:18504504 ferulic acid multiple interactions ISO Il18 (Mus musculus) 6480464 ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL18 mRNA] CTD PMID:31054998 fluvastatin multiple interactions EXP 6480464 Fluvastatin inhibits the reaction [bisphenol A results in increased expression of IL18 protein] more ... CTD PMID:35465754 folic acid multiple interactions ISO IL18 (Homo sapiens) 6480464 [Ethanol co-treated with Folic Acid] results in increased expression of IL18 mRNA CTD PMID:23378141 folic acid increases methylation ISO IL18 (Homo sapiens) 6480464 Folic Acid results in increased methylation of IL18 gene CTD PMID:30116142 folic acid increases expression ISO IL18 (Homo sapiens) 6480464 Folic Acid results in increased expression of IL18 mRNA CTD PMID:28752528 folic acid increases expression ISO Il18 (Mus musculus) 6480464 Folic Acid results in increased expression of IL18 protein CTD PMID:31593741 and PMID:35191561 folic acid multiple interactions ISO Il18 (Mus musculus) 6480464 [1 more ... CTD PMID:22206623 more ... folpet decreases expression ISO Il18 (Mus musculus) 6480464 folpet results in decreased expression of IL18 mRNA CTD PMID:31558096 formaldehyde increases expression ISO Il18 (Mus musculus) 6480464 Formaldehyde results in increased expression of IL18 mRNA CTD PMID:12161283 Fraxinellone multiple interactions ISO Il18 (Mus musculus) 6480464 fraxinellone inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein] and fraxinellone inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 protein] CTD PMID:25448682 Fraxinellone multiple interactions ISO IL18 (Homo sapiens) 6480464 fraxinellone inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 protein] CTD PMID:25448682 fructose increases expression EXP 6480464 Fructose results in increased expression of IL18 mRNA and Fructose results in increased expression of IL18 protein CTD PMID:18504504 and PMID:22426011 fructose multiple interactions EXP 6480464 Allopurinol inhibits the reaction [Fructose results in increased expression of IL18 protein] more ... CTD PMID:18504504 and PMID:22426011 fulvestrant multiple interactions ISO Il18 (Mus musculus) 6480464 [fulvestrant co-treated with Mifepristone] inhibits the reaction [[Progesterone co-treated with Estrogens] inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA]] CTD PMID:17850464 fulvestrant multiple interactions ISO IL18 (Homo sapiens) 6480464 Fulvestrant inhibits the reaction [bisphenol A affects the expression of IL18 mRNA] CTD PMID:35439536 fumonisin B1 increases secretion ISO Il18 (Mus musculus) 6480464 fumonisin B1 results in increased secretion of IL18 protein CTD PMID:36309173 fumonisin B1 multiple interactions ISO Il18 (Mus musculus) 6480464 deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL18 mRNA] more ... CTD PMID:36309173 fumonisin B1 increases expression ISO Il18 (Mus musculus) 6480464 fumonisin B1 results in increased expression of IL18 mRNA and fumonisin B1 results in increased expression of IL18 protein CTD PMID:36309173 furan decreases expression ISO Il18 (Mus musculus) 6480464 furan results in decreased expression of IL18 mRNA CTD PMID:20194422 furan increases expression ISO Il18 (Mus musculus) 6480464 furan results in increased expression of IL18 mRNA and furan results in increased expression of IL18 protein CTD PMID:34450210 furan multiple interactions ISO Il18 (Mus musculus) 6480464 rhodioloside inhibits the reaction [furan results in increased expression of IL18 mRNA] and rhodioloside inhibits the reaction [furan results in increased expression of IL18 protein] CTD PMID:34450210 genistein decreases expression EXP 6480464 Genistein results in decreased expression of IL18 mRNA CTD PMID:12075121 gentamycin decreases expression ISO IL18 (Homo sapiens) 6480464 Gentamicins results in decreased expression of IL18 mRNA CTD PMID:29992668 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of IL18 mRNA CTD PMID:33387578 geranial increases expression ISO IL18 (Homo sapiens) 6480464 citral results in increased expression of IL18 protein CTD PMID:23063874 geraniol multiple interactions ISO Il18 (Mus musculus) 6480464 geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide more ... CTD PMID:21430599 geraniol multiple interactions EXP 6480464 geraniol inhibits the reaction [Doxorubicin results in increased expression of IL18 protein] CTD PMID:34343525 glucose increases expression ISO IL18 (Homo sapiens) 6480464 Glucose results in increased expression of IL18 mRNA and Glucose results in increased expression of IL18 protein CTD PMID:36066211 and PMID:37473909 glucose multiple interactions ISO IL18 (Homo sapiens) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased secretion of IL18 protein more ... CTD PMID:35607288 more ... glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL18 protein and diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL18 protein] CTD PMID:35191607 glucose increases secretion ISO IL18 (Homo sapiens) 6480464 Glucose results in increased secretion of IL18 protein CTD PMID:35607288 glucose increases expression ISO Il18 (Mus musculus) 6480464 Glucose results in increased expression of IL18 mRNA CTD PMID:34212273 glucose increases secretion ISO Il18 (Mus musculus) 6480464 Glucose results in increased secretion of IL18 protein CTD PMID:34212273 glucose multiple interactions ISO Il18 (Mus musculus) 6480464 GSDMD protein affects the reaction [Glucose results in increased secretion of IL18 protein] and Hirudins inhibits the reaction [Glucose results in increased secretion of IL18 protein] CTD PMID:34212273 glyburide multiple interactions EXP 6480464 Glyburide inhibits the reaction [Paraquat results in increased expression of IL18 protein] CTD PMID:25338942 glyburide multiple interactions ISO Il18 (Mus musculus) 6480464 Glyburide inhibits the reaction [Ozone results in increased expression of IL18 protein] and Glyburide inhibits the reaction [Paraquat results in increased secretion of IL18 protein] CTD PMID:25338942 and PMID:32167222 glyoxal increases expression ISO IL18 (Homo sapiens) 6480464 Glyoxal results in increased expression of IL18 protein CTD PMID:23063874 gossypin multiple interactions EXP 6480464 gossypin inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 protein] CTD PMID:37148149 graphene oxide increases expression ISO Il18 (Mus musculus) 6480464 graphene oxide analog results in increased expression of IL18 mRNA and graphene oxide results in increased expression of IL18 mRNA CTD PMID:33227293 graphite increases expression EXP 6480464 Graphite results in increased expression of IL18 protein CTD PMID:29933104 hemin multiple interactions ISO IL18 (Homo sapiens) 6480464 Hemin inhibits the reaction [IL18 protein results in decreased expression of MAPK11 protein] more ... CTD PMID:18215737 hemin decreases response to substance ISO IL18 (Homo sapiens) 6480464 Hemin results in decreased susceptibility to IL18 protein CTD PMID:18215737 hexachlorobenzene increases expression EXP 6480464 Hexachlorobenzene results in increased expression of IL18 mRNA CTD PMID:15159207 hexadecanoic acid increases expression EXP 6480464 Palmitic Acid results in increased expression of IL18 mRNA and Palmitic Acid results in increased expression of IL18 protein CTD PMID:35235096 and PMID:37244597 hexadecanoic acid increases cleavage EXP 6480464 Palmitic Acid results in increased cleavage of IL18 protein CTD PMID:37244597 hexadecanoic acid multiple interactions EXP 6480464 Lead promotes the reaction [Palmitic Acid results in increased cleavage of IL18 protein] more ... CTD PMID:35235096 and PMID:37244597 histamine multiple interactions ISO IL18 (Homo sapiens) 6480464 [IL12A protein binds to IL12B protein] inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein]] more ... CTD PMID:11752121 more ... histamine increases expression ISO Il18 (Mus musculus) 6480464 Histamine results in increased expression of IL18 protein CTD PMID:16723495 histamine multiple interactions ISO Il18 (Mus musculus) 6480464 HRH2 protein affects the reaction [Histamine results in increased expression of IL18 protein] CTD PMID:16723495 histamine increases expression ISO IL18 (Homo sapiens) 6480464 Histamine results in increased expression of IL18 protein CTD PMID:16723495 Honokiol multiple interactions ISO IL18 (Homo sapiens) 6480464 honokiol inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 protein] CTD PMID:21147091 hydrocortisone succinate decreases secretion ISO IL18 (Homo sapiens) 6480464 hydrocortisone hemisuccinate results in decreased secretion of IL18 protein CTD PMID:20421217 hydrogen peroxide multiple interactions ISO IL18 (Homo sapiens) 6480464 Hydrogen Peroxide inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]] and Theophylline inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]]] CTD PMID:18951874 hydrogen peroxide decreases expression ISO IL18 (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased expression of IL18 mRNA CTD PMID:12419474 and PMID:26339600 hydrogen peroxide affects expression ISO IL18 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of IL18 mRNA CTD PMID:21179406 hydroquinone increases secretion ISO IL18 (Homo sapiens) 6480464 hydroquinone results in increased secretion of IL18 protein CTD PMID:36646296 hydroquinone multiple interactions ISO IL18 (Homo sapiens) 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased secretion of IL18 protein] more ... CTD PMID:36646296 hydroxysafflor yellow A multiple interactions ISO Il18 (Mus musculus) 6480464 hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased secretion of IL18 protein] CTD PMID:37001609 IC-87114 multiple interactions ISO Il18 (Mus musculus) 6480464 IC 87114 inhibits the reaction [Toluene 2 and 4-Diisocyanate results in increased secretion of IL18 protein] CTD PMID:33711354 ICI 118551 multiple interactions ISO Il18 (Mus musculus) 6480464 ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA] and ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of IL18 protein] CTD PMID:15178407 imiquimod increases expression ISO Il18 (Mus musculus) 6480464 Imiquimod results in increased expression of IL18 mRNA CTD PMID:31054998 imiquimod multiple interactions ISO Il18 (Mus musculus) 6480464 ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL18 mRNA] CTD PMID:31054998 immunological adjuvant multiple interactions ISO IL18 (Homo sapiens) 6480464 [Adjuvants more ... CTD PMID:17404311 indometacin increases expression EXP 6480464 Indomethacin results in increased expression of IL18 mRNA and Indomethacin results in increased expression of IL18 protein CTD PMID:18996434 irinotecan increases expression ISO Il18 (Mus musculus) 6480464 Irinotecan results in increased expression of IL18 mRNA and Irinotecan results in increased expression of IL18 protein CTD PMID:26431797 irinotecan multiple interactions ISO IL18 (Homo sapiens) 6480464 [Fluorouracil co-treated with Irinotecan] results in decreased expression of IL18 mRNA more ... CTD PMID:16391804 and PMID:26431797 irinotecan multiple interactions ISO Il18 (Mus musculus) 6480464 [Irinotecan co-treated with Lipopolysaccharides] results in increased expression of and results in increased secretion of IL18 protein more ... CTD PMID:26431797 iron atom multiple interactions ISO IL18 (Homo sapiens) 6480464 Iron affects the reaction [IL18 protein results in increased secretion of IFNG protein] CTD PMID:15799959 iron(0) multiple interactions ISO IL18 (Homo sapiens) 6480464 Iron affects the reaction [IL18 protein results in increased secretion of IFNG protein] CTD PMID:15799959 isoeugenol increases expression ISO IL18 (Homo sapiens) 6480464 isoeugenol results in increased expression of IL18 protein CTD PMID:23063874 isoflurane multiple interactions ISO Il18 (Mus musculus) 6480464 N-(1 more ... CTD PMID:35187972 isoflurane increases expression ISO Il18 (Mus musculus) 6480464 Isoflurane results in increased expression of IL18 protein CTD PMID:35187972 isoprenaline multiple interactions ISO Il18 (Mus musculus) 6480464 ADRB2 protein affects the reaction [Isoproterenol results in increased expression of IL18 mRNA] more ... CTD PMID:15178407 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of IL18 protein CTD PMID:24286936 isoprenaline decreases expression ISO Il18 (Mus musculus) 6480464 Isoproterenol results in decreased expression of IL18 mRNA CTD PMID:21335049 ivermectin decreases expression ISO IL18 (Homo sapiens) 6480464 Ivermectin results in decreased expression of IL18 protein CTD PMID:32959892 JTE-013 multiple interactions EXP 6480464 JTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased expression of IL18 protein] CTD PMID:37169277 L-methionine multiple interactions ISO Il18 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL18 mRNA more ... CTD PMID:37023836 lead diacetate affects expression ISO Il18 (Mus musculus) 6480464 lead acetate affects the expression of IL18 protein CTD PMID:21322097 lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of IL18 mRNA CTD PMID:33862172 lead(0) increases expression EXP 6480464 Lead results in increased expression of IL18 protein CTD PMID:37244597 lead(0) increases cleavage EXP 6480464 Lead results in increased cleavage of IL18 protein CTD PMID:37244597 lead(0) multiple interactions EXP 6480464 [Lead co-treated with Dietary Fats] results in increased cleavage of IL18 protein more ... CTD PMID:37244597 lipid As increases expression ISO IL18 (Homo sapiens) 6480464 Lipid A results in increased expression of IL18 mRNA CTD PMID:16299289 lipopolysaccharide multiple interactions ISO IL18 (Homo sapiens) 6480464 3-methyladenine promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] more ... CTD PMID:17399992 more ... lipopolysaccharide multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein more ... CTD PMID:35285579 more ... lipopolysaccharide increases secretion ISO IL18 (Homo sapiens) 6480464 Lipopolysaccharides results in increased secretion of IL18 protein CTD PMID:15289356 more ... lipopolysaccharide increases expression ISO IL18 (Homo sapiens) 6480464 Lipopolysaccharides results in increased expression of IL18 mRNA and Lipopolysaccharides results in increased expression of IL18 protein CTD PMID:16100009 more ... lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of IL18 mRNA and Lipopolysaccharides results in increased expression of IL18 protein CTD PMID:21882482 more ... lipopolysaccharide increases expression ISO Il18 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of IL18 mRNA and Lipopolysaccharides results in increased expression of IL18 protein CTD PMID:17321000 more ... lipopolysaccharide affects expression ISO Il18 (Mus musculus) 6480464 Lipopolysaccharides affects the expression of IL18 protein CTD PMID:21055422 lipopolysaccharide multiple interactions ISO Il18 (Mus musculus) 6480464 (+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA] more ... CTD PMID:15933225 more ... loganin multiple interactions ISO IL18 (Homo sapiens) 6480464 loganin inhibits the reaction [Glucose results in increased expression of IL18 mRNA] and loganin inhibits the reaction [Glucose results in increased expression of IL18 protein] CTD PMID:37473909 loganin multiple interactions ISO Il18 (Mus musculus) 6480464 loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL18 protein] and loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL18 mRNA] CTD PMID:37473909 lonafarnib multiple interactions ISO Il18 (Mus musculus) 6480464 geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide more ... CTD PMID:21430599 lonidamine multiple interactions ISO Il18 (Mus musculus) 6480464 lonidamine inhibits the reaction [[lipopolysaccharide more ... CTD PMID:36577999 lovastatin multiple interactions ISO Il18 (Mus musculus) 6480464 [Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide more ... CTD PMID:21430599 lucanthone decreases expression ISO IL18 (Homo sapiens) 6480464 Lucanthone results in decreased expression of IL18 mRNA CTD PMID:21148553 LY294002 increases expression ISO IL18 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of IL18 protein CTD PMID:30726812 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium bisulfide inhibits the reaction [uranyl acetate results in increased secretion of IL18 protein]] CTD PMID:36094782 LY294002 multiple interactions ISO IL18 (Homo sapiens) 6480464 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Benzo(a)pyrene] results in increased expression of IL18 protein CTD PMID:30726812 lycopene multiple interactions ISO Il18 (Mus musculus) 6480464 Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL18 protein] CTD PMID:36610486 lysophosphatidylcholine multiple interactions ISO IL18 (Homo sapiens) 6480464 GPR4 protein promotes the reaction [Lysophosphatidylcholines results in increased expression of IL18 protein] CTD PMID:34293432 lysophosphatidylcholine increases expression ISO IL18 (Homo sapiens) 6480464 Lysophosphatidylcholines results in increased expression of IL18 protein CTD PMID:34293432 m-xylene decreases expression EXP 6480464 3-xylene results in decreased expression of IL18 mRNA CTD PMID:12815608 manganese(II) chloride multiple interactions ISO Il18 (Mus musculus) 6480464 acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL18 mRNA] CTD PMID:28539244 manganese(II) chloride increases expression ISO Il18 (Mus musculus) 6480464 manganese chloride results in increased expression of IL18 mRNA CTD PMID:28539244 mangiferin multiple interactions EXP 6480464 mangiferin inhibits the reaction [Galactosamine results in increased expression of IL18 mRNA] CTD PMID:22310181 manumycin A multiple interactions ISO Il18 (Mus musculus) 6480464 geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide more ... CTD PMID:21430599 melatonin multiple interactions ISO Il18 (Mus musculus) 6480464 Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of IL18 mRNA] and Melatonin inhibits the reaction [Nickel results in increased expression of IL18 mRNA] CTD PMID:36504304 melittin increases expression ISO IL18 (Homo sapiens) 6480464 Melitten results in increased expression of IL18 protein CTD PMID:22973906 melittin multiple interactions ISO IL18 (Homo sapiens) 6480464 AIM2 protein promotes the reaction [Melitten results in increased expression of IL18 protein] CTD PMID:22973906 mesalamine multiple interactions ISO Il18 (Mus musculus) 6480464 Mesalamine inhibits the reaction [Dextran Sulfate results in increased secretion of IL18 protein] CTD PMID:37001609 metam multiple interactions ISO Il18 (Mus musculus) 6480464 methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA] CTD PMID:15933225 methamphetamine increases expression ISO Il18 (Mus musculus) 6480464 Methamphetamine results in increased expression of IL18 mRNA and Methamphetamine results in increased expression of IL18 protein CTD PMID:33359793 and PMID:35688268 methamphetamine multiple interactions ISO Il18 (Mus musculus) 6480464 [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased secretion of IL18 protein] and obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of IL18 mRNA] CTD PMID:35390362 and PMID:35688268 methamphetamine increases secretion ISO Il18 (Mus musculus) 6480464 Methamphetamine results in increased secretion of IL18 protein CTD PMID:35390362 methotrexate increases expression ISO IL18 (Homo sapiens) 6480464 Methotrexate results in increased expression of IL18 mRNA CTD PMID:17400583 methotrexate multiple interactions EXP 6480464 vanillin inhibits the reaction [Methotrexate results in increased expression of IL18 protein] CTD PMID:29216766 methotrexate multiple interactions ISO IL18 (Homo sapiens) 6480464 [Methotrexate co-treated with Glucocorticoids] results in decreased expression of IL18 mRNA CTD PMID:22133036 methoxyacetic acid affects expression ISO Il18 (Mus musculus) 6480464 methoxyacetic acid affects the expression of IL18 mRNA CTD PMID:20421339 metronidazole multiple interactions ISO Il18 (Mus musculus) 6480464 [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased secretion of IL18 protein] CTD PMID:35390362 mevalonic acid multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA]] CTD PMID:18660453 microcystin-LR increases expression EXP 6480464 cyanoginosin LR results in increased expression of IL18 protein CTD PMID:34740672 microcystin-LR multiple interactions EXP 6480464 [Dietary Fats co-treated with Cholesterol and Dietary co-treated with cyanoginosin LR] results in increased expression of IL18 protein CTD PMID:34740672 mifepristone multiple interactions ISO Il18 (Mus musculus) 6480464 [fulvestrant co-treated with Mifepristone] inhibits the reaction [[Progesterone co-treated with Estrogens] inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA]] CTD PMID:17850464 mitomycin C decreases expression ISO IL18 (Homo sapiens) 6480464 Mitomycin results in decreased expression of IL18 and Mitomycin results in decreased expression of IL18 protein CTD PMID:16019139 and PMID:17021654 Monobutylphthalate affects expression ISO Il18 (Mus musculus) 6480464 monobutyl phthalate affects the expression of IL18 mRNA CTD PMID:20421339 monocrotaline multiple interactions ISO Il18 (Mus musculus) 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA CTD PMID:21224054 muramyl dipeptide multiple interactions ISO Il18 (Mus musculus) 6480464 [Pamidronate results in increased susceptibility to Acetylmuramyl-Alanyl-Isoglutamine] which results in increased secretion of IL18 protein CTD PMID:21282739 mycophenolic acid decreases expression ISO Il18 (Mus musculus) 6480464 Mycophenolic Acid results in decreased expression of IL18 mRNA CTD PMID:19818335 mycotoxin increases expression ISO Il18 (Mus musculus) 6480464 Mycotoxins results in increased expression of IL18 mRNA CTD PMID:19818335 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO IL18 (Homo sapiens) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Cimetidine results in increased expression of IL18 protein] and N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Histamine results in increased expression of IL18 protein] CTD PMID:16723495 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO Il18 (Mus musculus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased secretion of IL18 protein] CTD PMID:37353053 N-acetyl-L-cysteine multiple interactions ISO Il18 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein] more ... CTD PMID:27311643 and PMID:35777681 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IL18 protein] and Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL18 protein] CTD PMID:35020164 and PMID:35285579 N-acetyl-L-cysteine multiple interactions ISO IL18 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] more ... CTD PMID:30205151 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Il18 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein] CTD PMID:15178407 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO IL18 (Homo sapiens) 6480464 [lipopolysaccharide more ... CTD PMID:34920032 N-nitrosodimethylamine multiple interactions ISO Il18 (Mus musculus) 6480464 CSF3 protein affects the reaction [Dimethylnitrosamine affects the expression of IL18 mRNA] CTD PMID:17869372 N-nitrosodimethylamine multiple interactions EXP 6480464 [Dietary Fats co-treated with Dimethylnitrosamine] results in increased expression of IL18 mRNA CTD PMID:32833043 N-nitrosodimethylamine affects expression ISO Il18 (Mus musculus) 6480464 Dimethylnitrosamine affects the expression of IL18 mRNA CTD PMID:17869372 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions ISO IL18 (Homo sapiens) 6480464 Ranitidine inhibits the reaction [Cimetidine results in increased expression of IL18 protein] more ... CTD PMID:11752121 and PMID:16723495 neomycin multiple interactions ISO Il18 (Mus musculus) 6480464 [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased secretion of IL18 protein] CTD PMID:35390362 nickel atom multiple interactions EXP 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in decreased expression of IL18 mRNA CTD PMID:22198552 nickel atom multiple interactions ISO Il18 (Mus musculus) 6480464 [SELENOM protein affects the susceptibility to Nickel] which affects the expression of IL18 mRNA more ... CTD PMID:36504304 nickel atom increases expression ISO Il18 (Mus musculus) 6480464 Nickel results in increased expression of IL18 mRNA CTD PMID:36504304 nickel atom decreases expression ISO IL18 (Homo sapiens) 6480464 Nickel results in decreased expression of IL18 mRNA CTD PMID:24768652 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of IL18 mRNA CTD PMID:22546817 nickel dichloride affects expression ISO Il18 (Mus musculus) 6480464 nickel chloride affects the expression of IL18 mRNA CTD PMID:24670797 nickel sulfate decreases expression ISO IL18 (Homo sapiens) 6480464 nickel sulfate results in decreased expression of IL18 mRNA CTD PMID:18651567 nickel sulfate increases expression ISO IL18 (Homo sapiens) 6480464 nickel sulfate results in increased expression of IL18 protein CTD PMID:23063874 nicotinamide multiple interactions EXP 6480464 [Streptozocin co-treated with Niacinamide co-treated with ENV-2 compound] results in decreased expression of IL18 mRNA CTD PMID:28322830 nicotine multiple interactions ISO IL18 (Homo sapiens) 6480464 CHRNA5 protein affects the reaction [Nicotine results in increased secretion of IL18 protein] CTD PMID:35131329 nicotine increases secretion ISO IL18 (Homo sapiens) 6480464 Nicotine results in increased secretion of IL18 protein CTD PMID:35131329 nifuroxazide multiple interactions EXP 6480464 nifuroxazide inhibits the reaction [Streptozocin results in increased expression of IL18 mRNA] CTD PMID:29291386 nilotinib multiple interactions ISO Il18 (Mus musculus) 6480464 nilotinib inhibits the reaction [Folic Acid results in increased expression of IL18 protein] CTD PMID:31593741 nitrofen increases expression EXP 6480464 nitrofen results in increased expression of IL18 mRNA CTD PMID:33484710 NMN zwitterion multiple interactions ISO Il18 (Mus musculus) 6480464 Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of IL18 protein] CTD PMID:30292833 NMN zwitterion multiple interactions EXP 6480464 Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of IL18 protein] CTD PMID:30292833 Nonylphenol increases expression ISO IL18 (Homo sapiens) 6480464 nonylphenol results in increased expression of IL18 protein CTD PMID:35998786 Nonylphenol increases expression EXP 6480464 nonylphenol results in increased expression of IL18 protein CTD PMID:35998786 obeticholic acid multiple interactions ISO Il18 (Mus musculus) 6480464 obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of IL18 mRNA] CTD PMID:35688268 ochratoxin A increases expression ISO Il18 (Mus musculus) 6480464 ochratoxin A results in increased expression of IL18 mRNA CTD PMID:33543323 oleic acid multiple interactions ISO IL18 (Homo sapiens) 6480464 [perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of IL18 mRNA and [perfluorodecanoic acid co-treated with Oleic Acid] results in increased secretion of IL18 protein CTD PMID:36423729 olmesartan multiple interactions EXP 6480464 olmesartan inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of IL18 mRNA CTD PMID:25729387 oxaliplatin increases expression EXP 6480464 oxaliplatin results in increased expression of IL18 mRNA CTD PMID:25729387 ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of IL18 mRNA CTD PMID:18636392 ozone increases expression ISO Il18 (Mus musculus) 6480464 Ozone results in increased expression of IL18 mRNA and Ozone results in increased expression of IL18 protein CTD PMID:32167222 and PMID:35928613 ozone multiple interactions ISO IL18 (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of Ozone] which results in increased expression of IL18 mRNA CTD PMID:22196529 ozone multiple interactions ISO Il18 (Mus musculus) 6480464 3-(4-t-butylphenyl)-N-(2 more ... CTD PMID:26731380 more ... ozone increases expression EXP 6480464 Ozone results in increased expression of IL18 protein CTD PMID:33383130 ozone decreases expression ISO Il18 (Mus musculus) 6480464 Ozone results in decreased expression of IL18 mRNA CTD PMID:26342085 paclitaxel increases expression ISO IL18 (Homo sapiens) 6480464 Paclitaxel results in increased expression of IL18 mRNA CTD PMID:31993881 paclitaxel multiple interactions ISO IL18 (Homo sapiens) 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of IL18 mRNA more ... CTD PMID:20705681 and PMID:31993881 paclitaxel increases secretion ISO IL18 (Homo sapiens) 6480464 Paclitaxel results in increased secretion of IL18 protein CTD PMID:31993881 Palbinone multiple interactions EXP 6480464 palbinone inhibits the reaction [Streptozocin results in increased expression of IL18 protein] CTD PMID:32202043 pamidronate multiple interactions ISO Il18 (Mus musculus) 6480464 [Pamidronate results in increased susceptibility to Acetylmuramyl-Alanyl-Isoglutamine] which results in increased secretion of IL18 protein CTD PMID:21282739 paracetamol affects expression ISO Il18 (Mus musculus) 6480464 Acetaminophen affects the expression of IL18 mRNA CTD PMID:17562736 paracetamol multiple interactions EXP 6480464 [boric acid results in increased abundance of Boron] inhibits the reaction [Acetaminophen results in increased expression of IL18 protein] and Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IL18 protein] CTD PMID:35020164 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of IL18 protein CTD PMID:35020164 paracetamol decreases expression ISO IL18 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of IL18 mRNA CTD PMID:31059760 paracetamol increases expression ISO IL18 (Homo sapiens) 6480464 Acetaminophen results in increased expression of IL18 mRNA CTD PMID:29067470 paracetamol multiple interactions ISO IL18 (Homo sapiens) 6480464 [Acetaminophen co-treated with Lipopolysaccharides] affects the expression of IL18 mRNA CTD PMID:31059760 paracetamol increases expression ISO Il18 (Mus musculus) 6480464 Acetaminophen results in increased expression of IL18 mRNA and Acetaminophen results in increased expression of IL18 protein CTD PMID:17585979 more ... paracetamol multiple interactions ISO Il18 (Mus musculus) 6480464 Aspirin inhibits the reaction [Acetaminophen results in increased expression of IL18 mRNA] more ... CTD PMID:19164858 and PMID:20102673 paraquat increases expression ISO IL18 (Homo sapiens) 6480464 Paraquat results in increased expression of IL18 mRNA CTD PMID:20883675 paraquat multiple interactions EXP 6480464 Glyburide inhibits the reaction [Paraquat results in increased expression of IL18 protein] more ... CTD PMID:25338942 and PMID:30025709 paraquat increases expression EXP 6480464 Paraquat results in increased expression of IL18 mRNA and Paraquat results in increased expression of IL18 protein CTD PMID:25338942 and PMID:30025709 paraquat multiple interactions ISO Il18 (Mus musculus) 6480464 Glyburide inhibits the reaction [Paraquat results in increased secretion of IL18 protein] and Silymarin inhibits the reaction [Paraquat results in increased secretion of IL18 protein] CTD PMID:25338942 and PMID:29054699 paraquat increases secretion ISO Il18 (Mus musculus) 6480464 Paraquat results in increased secretion of IL18 protein CTD PMID:25338942 and PMID:29054699 patulin multiple interactions ISO IL18 (Homo sapiens) 6480464 3-methyladenine inhibits the reaction [Patulin results in increased expression of IL18 protein] CTD PMID:33217525 PD 0325901 multiple interactions ISO IL18 (Homo sapiens) 6480464 mirdametinib inhibits the reaction [[IL15 protein co-treated with IL18 protein] results in increased secretion of IFNG protein] CTD PMID:27563819 pentachlorophenol increases expression ISO IL18 (Homo sapiens) 6480464 Pentachlorophenol results in increased expression of IL18 mRNA CTD PMID:35550411 pentane-2,3-dione increases expression EXP 6480464 2 and 3-pentanedione results in increased expression of IL18 mRNA CTD PMID:25710175 perfluorodecanoic acid increases expression ISO IL18 (Homo sapiens) 6480464 perfluorodecanoic acid results in increased expression of IL18 mRNA CTD PMID:36423729 perfluorodecanoic acid multiple interactions ISO IL18 (Homo sapiens) 6480464 [perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of IL18 mRNA and [perfluorodecanoic acid co-treated with Oleic Acid] results in increased secretion of IL18 protein CTD PMID:36423729 perfluorodecanoic acid increases secretion ISO IL18 (Homo sapiens) 6480464 perfluorodecanoic acid results in increased secretion of IL18 protein CTD PMID:36423729 perfluorohexanesulfonic acid increases expression ISO Il18 (Mus musculus) 6480464 perfluorohexanesulfonic acid results in increased expression of IL18 mRNA CTD PMID:37995155 perfluorooctane-1-sulfonic acid multiple interactions ISO Il18 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of IL18 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of IL18 mRNA CTD PMID:36331819 perfluoroundecanoic acid decreases expression ISO IL18 (Homo sapiens) 6480464 perfluoroundecanoic acid results in decreased expression of IL18 protein CTD PMID:32916415 permethrin multiple interactions ISO Il18 (Mus musculus) 6480464 [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL18 protein and NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL18 protein] CTD PMID:32832901 phenethyl caffeate multiple interactions ISO IL18 (Homo sapiens) 6480464 caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL18 mRNA] CTD PMID:16085347 phenytoin multiple interactions ISO Il18 (Mus musculus) 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA CTD PMID:21224054 phosgene increases expression EXP 6480464 Phosgene results in increased expression of IL18 protein CTD PMID:33012731 phosgene multiple interactions EXP 6480464 NLRP3 protein promotes the reaction [Phosgene results in increased expression of IL18 protein] CTD PMID:33012731 phthalic anhydride increases activity ISO Il18 (Mus musculus) 6480464 phthalic anhydride results in increased activity of IL18 protein CTD PMID:15840424 Phytolaccoside E increases secretion ISO IL18 (Homo sapiens) 6480464 esculentoside A results in increased secretion of IL18 protein CTD PMID:36460195 Phytolaccoside E increases expression ISO Il18 (Mus musculus) 6480464 esculentoside A results in increased expression of IL18 protein CTD PMID:36460195 pioglitazone multiple interactions EXP 6480464 pioglitazone inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 pirinixic acid multiple interactions ISO Il18 (Mus musculus) 6480464 [pirinixic acid co-treated with PPARA] results in decreased expression of IL18 mRNA and PPARA protein affects the reaction [pirinixic acid results in decreased expression of IL18 mRNA] CTD PMID:17321000 and PMID:20813756 pirinixic acid decreases expression ISO Il18 (Mus musculus) 6480464 pirinixic acid results in decreased expression of IL18 mRNA CTD PMID:17321000 more ... prednisolone multiple interactions ISO Il18 (Mus musculus) 6480464 Prednisolone inhibits the reaction [Picryl Chloride results in increased expression of IL18 protein] CTD PMID:16442096 procyanidin B2 multiple interactions EXP 6480464 procyanidin B2 inhibits the reaction [Paraquat results in increased expression of IL18 mRNA] and procyanidin B2 inhibits the reaction [Paraquat results in increased expression of IL18 protein] CTD PMID:30025709 progesterone multiple interactions ISO Il18 (Mus musculus) 6480464 [fulvestrant co-treated with Mifepristone] inhibits the reaction [[Progesterone co-treated with Estrogens] inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA]] more ... CTD PMID:17850464 propofol multiple interactions ISO IL18 (Homo sapiens) 6480464 Lipopolysaccharides promotes the reaction [Propofol results in increased expression of IL18 mRNA] CTD PMID:35953652 propofol increases expression ISO IL18 (Homo sapiens) 6480464 Propofol results in increased expression of IL18 mRNA CTD PMID:35953652 protein kinase inhibitor multiple interactions ISO IL18 (Homo sapiens) 6480464 Protein Kinase Inhibitors inhibits the reaction [IL18 protein results in increased expression of IFNG protein] CTD PMID:28003376 pterostilbene multiple interactions ISO IL18 (Homo sapiens) 6480464 pterostilbene inhibits the reaction [Ethanol results in increased expression of IL18 protein] and RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL18 protein]] CTD PMID:34474091 puerarin multiple interactions ISO IL18 (Homo sapiens) 6480464 PRKAA1 protein promotes the reaction [puerarin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein]] more ... CTD PMID:35331853 Pyridostigmine bromide multiple interactions ISO Il18 (Mus musculus) 6480464 [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL18 protein and NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL18 protein] CTD PMID:32832901 pyrrolidine dithiocarbamate multiple interactions ISO Il18 (Mus musculus) 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of IL18 protein] and pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA] CTD PMID:15178407 quartz multiple interactions EXP 6480464 Tobacco Smoke Pollution promotes the reaction [Quartz results in increased secretion of IL18 protein] CTD PMID:32976597 quartz increases secretion EXP 6480464 Quartz results in increased secretion of IL18 protein CTD PMID:32976597 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Fructose results in increased expression of IL18 protein] and Quercetin inhibits the reaction [Streptozocin results in increased expression of IL18 protein] CTD PMID:22426011 and PMID:23647015 quercetin multiple interactions ISO IL18 (Homo sapiens) 6480464 Quercetin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein] more ... CTD PMID:34791735 rac-lactic acid decreases expression ISO IL18 (Homo sapiens) 6480464 Lactic Acid results in decreased expression of IL18 mRNA CTD PMID:30851411 ranitidine multiple interactions ISO IL18 (Homo sapiens) 6480464 Ranitidine inhibits the reaction [Cimetidine results in increased expression of IL18 protein] more ... CTD PMID:11752121 and PMID:16723495 reactive oxygen species increases abundance ISO IL18 (Homo sapiens) 6480464 IL18 protein results in increased abundance of Reactive Oxygen Species CTD PMID:19561311 reactive oxygen species multiple interactions ISO IL18 (Homo sapiens) 6480464 diphenyleneiodonium inhibits the reaction [IL18 protein results in increased abundance of Reactive Oxygen Species] and resveratrol inhibits the reaction [IL18 protein results in increased abundance of Reactive Oxygen Species] CTD PMID:19561311 Rebamipide increases expression EXP 6480464 rebamipide results in increased expression of IL18 mRNA CTD PMID:18299717 reserpine increases expression EXP 6480464 Reserpine results in increased expression of IL18 mRNA CTD PMID:8999896 resorcinol increases expression ISO IL18 (Homo sapiens) 6480464 resorcinol results in increased expression of IL18 mRNA and resorcinol results in increased expression of IL18 protein CTD PMID:23063874 and PMID:30806763 resveratrol multiple interactions ISO IL18 (Homo sapiens) 6480464 resveratrol inhibits the reaction [BSG protein results in increased expression of and results in increased secretion of IL18 protein] more ... CTD PMID:19561311 and PMID:24149798 resveratrol multiple interactions ISO Il18 (Mus musculus) 6480464 Resveratrol inhibits the reaction [Aluminum Chloride results in increased expression of IL18 protein] CTD PMID:34614429 and PMID:35156769 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL18 mRNA] and resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL18 protein] CTD PMID:26464617 Rhein multiple interactions ISO Il18 (Mus musculus) 6480464 rhein inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL18 protein] CTD PMID:37023836 rifampicin multiple interactions ISO Il18 (Mus musculus) 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA CTD PMID:21224054 rimonabant multiple interactions ISO IL18 (Homo sapiens) 6480464 Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of IL18 protein] CTD PMID:27932991 rolipram multiple interactions ISO Il18 (Mus musculus) 6480464 Rolipram inhibits the reaction [Picryl Chloride results in increased expression of IL18 protein] CTD PMID:16442096 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of IL18 mRNA CTD PMID:28374803 rotenone multiple interactions ISO IL18 (Homo sapiens) 6480464 Rotenone promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased cleavage of IL18 protein] and Rotenone promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] CTD PMID:30205151 rutin multiple interactions EXP 6480464 Rutin inhibits the reaction [Fructose results in increased expression of IL18 protein] CTD PMID:22426011 rutin decreases expression EXP 6480464 Rutin results in decreased expression of IL18 mRNA CTD PMID:28693884 Salidroside multiple interactions ISO Il18 (Mus musculus) 6480464 rhodioloside inhibits the reaction [furan results in increased expression of IL18 mRNA] and rhodioloside inhibits the reaction [furan results in increased expression of IL18 protein] CTD PMID:34450210 sarpogrelate decreases expression ISO IL18 (Homo sapiens) 6480464 sarpogrelate results in decreased expression of IL18 protein CTD PMID:15080020 SB 203580 multiple interactions ISO IL18 (Homo sapiens) 6480464 SB 203580 inhibits the reaction [IL18 protein results in increased expression of PTEN mRNA] more ... CTD PMID:18215737 scutellarin multiple interactions EXP 6480464 scutellarin inhibits the reaction [Streptozocin results in increased expression of IL18 protein] CTD PMID:37081038 serpentine asbestos decreases expression ISO IL18 (Homo sapiens) 6480464 Asbestos and Serpentine results in decreased expression of IL18 mRNA CTD PMID:24160326 sevoflurane increases expression EXP 6480464 Sevoflurane results in increased expression of IL18 mRNA and Sevoflurane results in increased expression of IL18 protein CTD PMID:36047109 and PMID:36155068 sevoflurane increases expression ISO IL18 (Homo sapiens) 6480464 Sevoflurane results in increased expression of IL18 mRNA CTD PMID:35953652 sevoflurane multiple interactions EXP 6480464 PHLDA1 protein promotes the reaction [Sevoflurane results in increased expression of IL18 protein] more ... CTD PMID:36047109 and PMID:36155068 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of IL18 mRNA CTD PMID:32721576 silicon dioxide multiple interactions ISO Il18 (Mus musculus) 6480464 3-(5-(2 more ... CTD PMID:27311643 silicon dioxide increases secretion ISO Il18 (Mus musculus) 6480464 Silicon Dioxide analog results in increased secretion of IL18 protein CTD PMID:27311643 silicon dioxide increases expression ISO IL18 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of IL18 mRNA and Silicon Dioxide results in increased expression of IL18 protein CTD PMID:23806026 and PMID:34766707 silver atom decreases expression ISO Il18 (Mus musculus) 6480464 Silver results in decreased expression of IL18 mRNA CTD PMID:27131904 silver(0) decreases expression ISO Il18 (Mus musculus) 6480464 Silver results in decreased expression of IL18 mRNA CTD PMID:27131904 simvastatin multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA]] and Simvastatin inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 simvastatin multiple interactions ISO IL18 (Homo sapiens) 6480464 Simvastatin promotes the reaction [Lipopolysaccharides results in increased secretion of IL18 protein] CTD PMID:27377765 sirolimus multiple interactions ISO IL18 (Homo sapiens) 6480464 Sirolimus inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] CTD PMID:30205151 sodium arsenite decreases expression ISO Il18 (Mus musculus) 6480464 sodium arsenite results in decreased expression of IL18 mRNA CTD PMID:21911445 sodium arsenite increases expression ISO Il18 (Mus musculus) 6480464 sodium arsenite results in increased expression of IL18 mRNA CTD PMID:37682722 sodium arsenite multiple interactions ISO IL18 (Homo sapiens) 6480464 [lipopolysaccharide more ... CTD PMID:34920032 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of IL18 protein CTD PMID:32593899 more ... sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of IL18 mRNA CTD PMID:22561333 Soman increases expression EXP 6480464 Soman results in increased expression of IL18 mRNA CTD PMID:19281266 sphingosine 1-phosphate multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [sphingosine 1-phosphate results in increased expression of IL18 protein] more ... CTD PMID:37169277 spironolactone multiple interactions EXP 6480464 Spironolactone inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 sterigmatocystin increases expression ISO Il18 (Mus musculus) 6480464 Sterigmatocystin results in increased expression of IL18 mRNA CTD PMID:19818335 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of IL18 mRNA and Streptozocin results in increased expression of IL18 protein CTD PMID:23647015 more ... streptozocin increases expression ISO Il18 (Mus musculus) 6480464 Streptozocin results in increased expression of IL18 mRNA and Streptozocin results in increased expression of IL18 protein CTD PMID:34212273 streptozocin multiple interactions ISO Il18 (Mus musculus) 6480464 [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL18 protein more ... CTD PMID:34212273 more ... streptozocin multiple interactions EXP 6480464 [Streptozocin co-treated with Niacinamide co-treated with ENV-2 compound] results in decreased expression of IL18 mRNA more ... CTD PMID:23647015 more ... sulfamic acid increases expression ISO IL18 (Homo sapiens) 6480464 sulfamic acid results in increased expression of IL18 protein CTD PMID:23063874 sulfasalazine multiple interactions EXP 6480464 Sulfasalazine inhibits the reaction [Acetic Acid results in increased expression of IL18 protein] CTD PMID:35595039 sulfur dioxide increases expression EXP 6480464 Sulfur Dioxide results in increased expression of IL18 protein CTD PMID:27565714 tetrachloromethane decreases expression ISO Il18 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of IL18 mRNA CTD PMID:27339419 and PMID:31919559 thalidomide increases expression ISO Il18 (Mus musculus) 6480464 Thalidomide results in increased expression of IL18 CTD PMID:17089043 thapsigargin increases expression ISO IL18 (Homo sapiens) 6480464 Thapsigargin results in increased expression of IL18 mRNA CTD PMID:30796460 theophylline multiple interactions ISO IL18 (Homo sapiens) 6480464 Theophylline inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]]] and Theophylline inhibits the reaction [Tobacco Smoke Pollution inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]]] CTD PMID:18951874 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of IL18 mRNA CTD PMID:34492290 thiram increases expression ISO IL18 (Homo sapiens) 6480464 Thiram results in increased expression of IL18 protein CTD PMID:23063874 tipifarnib multiple interactions ISO Il18 (Mus musculus) 6480464 geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide more ... CTD PMID:21430599 titanium dioxide multiple interactions ISO Il18 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL18 mRNA CTD PMID:29950665 TMC-120A increases expression ISO Il18 (Mus musculus) 6480464 TMC 120A results in increased expression of IL18 mRNA CTD PMID:19818335 toluene 2,4-diisocyanate increases expression ISO Il18 (Mus musculus) 6480464 Toluene 2 and 4-Diisocyanate results in increased expression of IL18 protein CTD PMID:31070765 toluene 2,4-diisocyanate multiple interactions ISO Il18 (Mus musculus) 6480464 2-(1 more ... CTD PMID:30517707 more ... toluene 2,4-diisocyanate increases secretion ISO Il18 (Mus musculus) 6480464 Toluene 2 and 4-Diisocyanate results in increased secretion of IL18 protein CTD PMID:30517707 and PMID:33711354 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of IL18 mRNA CTD PMID:25729387 topotecan increases expression EXP 6480464 Topotecan results in increased expression of IL18 mRNA CTD PMID:25729387 trans-isoeugenol increases expression ISO IL18 (Homo sapiens) 6480464 isoeugenol results in increased expression of IL18 protein CTD PMID:23063874 trichostatin A increases expression ISO IL18 (Homo sapiens) 6480464 trichostatin A results in increased expression of IL18 mRNA CTD PMID:24935251 Triptolide decreases expression ISO Il18 (Mus musculus) 6480464 triptolide results in decreased expression of IL18 mRNA CTD PMID:32835833 Triptolide multiple interactions ISO Il18 (Mus musculus) 6480464 [triptolide co-treated with Lipopolysaccharides] results in increased expression of IL18 mRNA and [triptolide co-treated with Lipopolysaccharides] results in increased secretion of IL18 protein CTD PMID:36328986 trovafloxacin multiple interactions ISO Il18 (Mus musculus) 6480464 IL18 protein results in increased susceptibility to [trovafloxacin co-treated with lipopolysaccharide more ... CTD PMID:18930950 and PMID:19638433 tungsten multiple interactions EXP 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in decreased expression of IL18 mRNA CTD PMID:22198552 ubiquinone-0 multiple interactions ISO IL18 (Homo sapiens) 6480464 ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein] CTD PMID:36847822 ubiquinone-0 decreases expression ISO IL18 (Homo sapiens) 6480464 ubiquinone-O results in decreased expression of IL18 protein CTD PMID:36847822 undecan-2-one multiple interactions ISO Il18 (Mus musculus) 6480464 undecan-2-one inhibits the reaction [Particulate Matter results in increased expression of IL18 protein] CTD PMID:35285579 uranium atom decreases secretion ISO Il18 (Mus musculus) 6480464 Uranium results in decreased secretion of IL18 protein CTD PMID:23659960 usnic acid multiple interactions ISO IL18 (Homo sapiens) 6480464 [usnic acid co-treated with Lipopolysaccharides] results in increased expression of IL18 mRNA CTD PMID:22777745 valproic acid affects expression ISO Il18 (Mus musculus) 6480464 Valproic Acid affects the expression of IL18 mRNA CTD PMID:20421339 valproic acid increases expression ISO IL18 (Homo sapiens) 6480464 Valproic Acid results in increased expression of IL18 mRNA CTD PMID:23179753 vancomycin multiple interactions ISO Il18 (Mus musculus) 6480464 [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased secretion of IL18 protein] CTD PMID:35390362 vanillin multiple interactions EXP 6480464 vanillin inhibits the reaction [Cisplatin results in increased expression of IL18 protein] and vanillin inhibits the reaction [Methotrexate results in increased expression of IL18 protein] CTD PMID:29216766 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of IL18 mRNA CTD PMID:18629315 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of IL18 mRNA CTD PMID:19015723 vorinostat decreases expression ISO IL18 (Homo sapiens) 6480464 vorinostat results in decreased expression of IL18 protein CTD PMID:17593366 wortmannin multiple interactions ISO Il18 (Mus musculus) 6480464 wortmannin inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein] CTD PMID:15178407 zearalenone increases secretion ISO Il18 (Mus musculus) 6480464 Zearalenone results in increased secretion of IL18 protein CTD PMID:30270565 zearalenone multiple interactions ISO Il18 (Mus musculus) 6480464 [Dextran Sulfate co-treated with Zearalenone] results in increased expression of IL18 mRNA more ... CTD PMID:30270565 zearalenone increases expression ISO Il18 (Mus musculus) 6480464 Zearalenone results in increased expression of IL18 mRNA CTD PMID:30270565 zinc protoporphyrin multiple interactions ISO IL18 (Homo sapiens) 6480464 zinc protoporphyrin inhibits the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL18 protein]] and zinc protoporphyrin inhibits the reaction [Hemin results in decreased susceptibility to IL18 protein] CTD PMID:18215737 and PMID:36858639 zirconium atom increases expression ISO IL18 (Homo sapiens) 6480464 Zirconium results in increased expression of IL18 protein CTD PMID:16100009
