Nicn1 (nicolin 1, tubulin polyglutamylase complex subunit)

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Gene: Nicn1 (nicolin 1, tubulin polyglutamylase complex subunit) Rattus norvegicus

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Symbol:

Nicn1

Name:

nicolin 1, tubulin polyglutamylase complex subunit

RGD ID:

1589574

Description:

Predicted to be active in nucleoplasm. Orthologous to human NICN1 (nicolin 1, tubulin polyglutamylase complex subunit); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

nicolin 1; nicolin-1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	117,854,210 - 117,860,185 (+)	NCBI		GRCr8
mRatBN7.2	8	108,976,393 - 108,981,620 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	108,976,464 - 108,981,067 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	114,603,617 - 114,608,773 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	112,802,940 - 112,808,097 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	110,645,580 - 110,650,736 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	117,062,989 - 117,068,134 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	117,062,884 - 117,068,130 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	116,415,763 - 116,420,985 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	8	108,279,495 - 108,284,640 (+)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Aicardi-Goutieres Syndrome 1 (ISO)

autosomal recessive limb-girdle muscular dystrophy type 2P (ISO)

carnitine-acylcarnitine translocase deficiency (ISO)

genetic disease (ISO)

glycine encephalopathy (ISO)

glycine encephalopathy 1 (ISO)

glycine encephalopathy 2 (ISO)

Pierson syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

amitrole (EXP)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cisplatin (ISO)

clofibrate (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

dibutyl phthalate (EXP,ISO)

doxorubicin (ISO)

ethanol (ISO)

finasteride (EXP)

fipronil (EXP)

gentamycin (EXP)

indometacin (ISO)

methimazole (EXP)

methylmercury chloride (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

rotenone (EXP)

sulfadimethoxine (EXP)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

nucleoplasm (IBA,ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Nicn1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	117,854,210 - 117,860,185 (+)	NCBI		GRCr8
mRatBN7.2	8	108,976,393 - 108,981,620 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	108,976,464 - 108,981,067 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	114,603,617 - 114,608,773 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	112,802,940 - 112,808,097 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	110,645,580 - 110,650,736 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	117,062,989 - 117,068,134 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	117,062,884 - 117,068,130 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	116,415,763 - 116,420,985 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	8	108,279,495 - 108,284,640 (+)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

NICN1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	49,422,333 - 49,429,324 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	49,422,333 - 49,429,326 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	49,459,766 - 49,466,757 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	49,434,770 - 49,441,761 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	49,435,383 - 49,441,725	NCBI
Celera	3	49,424,553 - 49,431,543 (-)	NCBI		Celera
Cytogenetic Map	3	p21.31	NCBI
HuRef	3	49,519,494 - 49,526,483 (-)	NCBI		HuRef
CHM1_1	3	49,412,534 - 49,419,525 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	49,451,717 - 49,458,707 (-)	NCBI		T2T-CHM13v2.0

Nicn1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	108,167,642 - 108,173,697 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	108,167,628 - 108,173,697 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	108,290,443 - 108,296,498 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	108,290,429 - 108,296,498 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	108,192,788 - 108,198,827 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	108,148,550 - 108,154,589 (+)	NCBI		MGSCv36	mm8
Celera	9	107,899,500 - 107,905,538 (+)	NCBI		Celera
Cytogenetic Map	9	F2	NCBI
cM Map	9	59.18	NCBI

Nicn1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955532	1,358,251 - 1,363,470 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955532	1,358,251 - 1,363,481 (-)	NCBI	ChiLan1.0	ChiLan1.0

NICN1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	49,405,118 - 49,411,840 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	49,409,890 - 49,416,303 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	49,350,753 - 49,357,161 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	50,595,232 - 50,601,612 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	50,595,232 - 50,601,612 (-)	Ensembl	panpan1.1		panPan2

NICN1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	39,810,692 - 39,814,354 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	39,810,692 - 39,814,354 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	39,729,143 - 39,732,805 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	40,166,922 - 40,170,584 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	20	39,534,469 - 39,538,131 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	39,938,081 - 39,941,743 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	40,217,671 - 40,221,333 (+)	NCBI		UU_Cfam_GSD_1.0

Nicn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	64,294,071 - 64,299,078 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	1,052,090 - 1,059,617 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936529	1,054,568 - 1,059,575 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NICN1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	32,002,660 - 32,007,217 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	32,002,658 - 32,007,266 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

NICN1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	10,821,663 - 10,825,405 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	10,820,757 - 10,825,462 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	156,187,974 - 156,192,692 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nicn1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	3,372,676 - 3,377,279 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	3,372,456 - 3,377,308 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Nicn1
21 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	136
Count of miRNA genes:	106
Interacting mature miRNAs:	117
Transcripts:	ENSRNOT00000071540
Prediction methods:	Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	61290298	119084929	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	73473045	118473045	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	69349194	112783834	Rat
1358903	Bp252	Blood pressure QTL 252	7	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	93965141	123900184	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	40952565	123900184	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	71888757	116888757	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	71888757	116888757	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	10378157	112202585	Rat
631653	Bp125	Blood pressure QTL 125	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	66142385	111142385	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	8462195	110921472	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	93535351	123900184	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	100149864	120994388	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	46531639	119088626	Rat
738014	Anxrr15	Anxiety related response QTL 15	3.6	0.005	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	95718998	123900184	Rat
2300182	Bmd56	Bone mineral density QTL 56	5.4		femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	95718998	123900184	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	76468691	121468691	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	70513503	118219066	Rat
1358893	Bp263	Blood pressure QTL 263	5.01		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	93965141	123900184	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	89265192	114019816	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	71888757	116888757	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	71888757	116888757	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	82460758	122812818	Rat

Markers in Region

RH130709

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	108,981,353 - 108,981,571 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	117,067,870 - 117,068,087	NCBI	Rnor6.0
Rnor_5.0	8	116,420,719 - 116,420,936	UniSTS	Rnor5.0
Celera	8	108,284,376 - 108,284,593	UniSTS
RH 3.4 Map	8	1118.3	UniSTS
Cytogenetic Map	8	q32	UniSTS

RH140216

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	108,980,521 - 108,980,734 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	117,067,038 - 117,067,250	NCBI	Rnor6.0
Rnor_5.0	8	116,419,887 - 116,420,099	UniSTS	Rnor5.0
Celera	8	108,283,544 - 108,283,756	UniSTS
RH 3.4 Map	8	1120.8	UniSTS
Cytogenetic Map	8	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001034999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC101861	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229605	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229763	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000071540 ⟹ ENSRNOP00000066822

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	8	117,062,989 - 117,068,130 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000082452 ⟹ ENSRNOP00000069769

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	108,976,464 - 108,981,067 (+)	Ensembl
Rnor_6.0 Ensembl	8	117,062,884 - 117,067,781 (+)	Ensembl

RefSeq Acc Id:

NM_001034999 ⟹ NP_001030171

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	117,855,038 - 117,860,183 (+)	NCBI
mRatBN7.2	8	108,976,472 - 108,981,618 (+)	NCBI
Rnor_6.0	8	117,062,989 - 117,068,134 (+)	NCBI
Rnor_5.0	8	116,415,763 - 116,420,985 (+)	NCBI
Celera	8	108,279,495 - 108,284,640 (+)	RGD

Sequence:

show sequence

GGCGACGCCAATAAGGGCTAGTGGTTGGATGGAGACTGTTAGCGGTGATTTCGCTTGATTGTAG
CCTCCCAAATCATGTCCCGTGTAGTGGTGCCCTGTCATGTGAAAAGCACTGTCGCCCTGCAAGT
GGGCGACATGAGGACCTCCCAAGGTCGGCCTGGCGTGCTAGTCGTCGATGTCACTTTTCCCAAC
GTCGCGCCTTTCGAGCTGCAGGAGATCACGTTTAAGAATTACTACACAGCTTTTTTGAGCATCC
GCGTTCGTCAGCAGACCCTGATGCACACACCAGCCAAGTGGGTAACTTGTCTGCGGGACTACTG
TTTGATGCCTGACCCACACAGTGAGGAGGGAGCCCAGGAGTATGTGTCACTGTTCAAGCACCAG
ATGCTGTGTGACATGAACAGAATACTGGAGCTGCGTCTGATTCTGCGGCAGCCGTCACCACTGT
GGCTGTCTTTCTCCGTGGAGGAACTGCAAATCTACCAGCAAGGACCAAAGAGCCCCTCCTTGGC
TTTCCCCAAGTGGCTTTCCCACCCAGTGTCCAATGAGCAGCCTGCTCCCCGCCTTGAGGGTCTC
CCAGACCCCAGCAGAGTCTCCTCTGAGGTGCAGCAGATGTGGGCATTGACAGAGATGATCCGGG
CTAATCATACTTCCACAAGGATCGGCCGCTTTGACGTGGACGGCTGTTATGATCTGAATTTACT
CTCCTACACGTAAGCAGCAGCTTCTACTGGAGACATTGGCCTTCTGTGCCCATCTAGGTGGGGT
TTGGCCACCAGAGGCCGAAGCACGTTCCCTGTGCATCCAAGTTCTATCTGGGCAAAATCTACAG
ATTAGGAATTCTTGACATCCATCCAGTTGTTTTAGCATGAATTCCTCGTGGGGGGCACTTTCTG
CCTTTGACTGTCCGACATGTAAATCCAGTCTCTTCCTCTCAGAATTCACCGGTTCGAATTAGAA
TCCTTGAATCCTTGAGCTCCTCTGGATTGTCCTGTCAATATGCACACCCCAGTCCTCTACCCCT
TCCCCCATTGCCGAGATAAACCTGTCATATGTAGCTGAGGAAGACACTGCTGTTTTGACACTCC
TGACCTGGGAAGCTTGGGGAAGACACACCTTCTATTCCCACCTCACCCCCAGCCTCCCTTTTGC
TAATAGCCTTTGTCATTTCATCTTAGCGTTTTGTGAGTTCAAGAACAGCCTAGTCTACACAGTG
AATCCCAGGCCAATTAGGGCTACATAGTGATACTTCATATTAAAAAAGAAAGAAAAGGAAGGAA
GGAAGGAAGAAAAAGAGAAAGAAAGGAAAGAAGAAAGAAAATAGCCCCCTTTGAAATTGTCTGC
TACCAGCCTAGGGTGTGAAGATGAGATTCCTGGGAGCTTGAATGCTTATGTCCCTAGGCTGGCT
CCTGAAAAGTGTCCTGTGTCAGTTCTGGGCAGGTGCTGTTGGCACAGCCGGGGGCGGAGAACGA
GTCCTCCCTCCCTCCGGCCTGTTTGTCATCAGACTCAGCATGAAGCACTTCCGTGTTCCTCTTC
CCTTCTCTCAGTTGCTTCTGCCCATCCTGCCCAGAGTGACGAGAAAGCAACCCTGGGGGAGTGC
GTCCAAACAAACGTCTCACTGATATTCACTGAGGCTGAGGCTCTCCATTACCCCAGAGCAACCA
CTAAATGAAGACGACTGCTGCTCTTTCCCGTGATCAAACCGCTTCCCTCTAGTTCTTCCTGGGA
ACTATTCTTAAGCTATGCTGCAAGGTGTCTCAGAACTGGAAAACTGCACATGAGTAAGTGCAGC
AGTTCTGGGAAAGTCTGTCCACCTTTTGATAGCTACCCTGCATTCTTGCAGTCAGCCCTCTTAA
AGGTCCTGTCTTCAGCTACAGGACGGTAGTTTAAGCCCCACTCAGTTTTTTTTTGTTTTTTGTT
TTTTGGGTCTTTTGTTTGTTTGTTTGTTTTTTCTTTTCTGAAAGGATAATTAACACCGTCCTGT
GTTCAGGGAGTCAATGGTCTTCAGAAGGAATGAGTAAAGAGGGTCCTGAGGTGGCAGGGACTGT
GCATAATGCGCAGCTGTGTCCCTAAGTTCCCAGAGCAGGAGCTAGAGTGCAGCAAGATCAATAA
ACACTTGTGGAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039082065 ⟹ XP_038937993

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	117,854,210 - 117,860,185 (+)	NCBI
mRatBN7.2	8	108,976,393 - 108,981,620 (+)	NCBI

RefSeq Acc Id:

XM_039082066 ⟹ XP_038937994

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	117,856,994 - 117,860,185 (+)	NCBI
mRatBN7.2	8	108,978,429 - 108,981,142 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001030171	(Get FASTA)	NCBI Sequence Viewer
	XP_038937993	(Get FASTA)	NCBI Sequence Viewer
	XP_038937994	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI01862	(Get FASTA)	NCBI Sequence Viewer
	EDL77186	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000069769.2

RefSeq Acc Id:

NP_001030171 ⟸ NM_001034999

- UniProtKB:

Q3T1K9 (UniProtKB/TrEMBL), A0A0G2JW73 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSRVVVPCHVKSTVALQVGDMRTSQGRPGVLVVDVTFPNVAPFELQEITFKNYYTAFLSIRVRQ
QTLMHTPAKWVTCLRDYCLMPDPHSEEGAQEYVSLFKHQMLCDMNRILELRLILRQPSPLWLSF
SVEELQIYQQGPKSPSLAFPKWLSHPVSNEQPAPRLEGLPDPSRVSSEVQQMWALTEMIRANHT
STRIGRFDVDGCYDLNLLSYT

hide sequence

Ensembl Acc Id:

ENSRNOP00000069769 ⟸ ENSRNOT00000082452

Ensembl Acc Id:

ENSRNOP00000066822 ⟸ ENSRNOT00000071540

RefSeq Acc Id:	XP_038937993 ⟸ XM_039082065
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JW73 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038937994 ⟸ XM_039082066
- Peptide Label:	isoform X2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2JW73-F1-model_v2	AlphaFold	A0A0G2JW73	1-221	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696292

Promoter ID:

EPDNEW_R6817

Type:

initiation region

Name:

Nicn1_1

Description:

nicolin 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	117,062,985 - 117,063,045	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1589574	AgrOrtholog
BioCyc Gene	G2FUF-29153	BioCyc
Ensembl Genes	ENSRNOG00000049083	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000082452.2	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7936966	IMAGE-MGC_LOAD
InterPro	Nicolin-1	UniProtKB/TrEMBL
KEGG Report	rno:619581	UniProtKB/TrEMBL
MGC_CLONE	MGC:124727	IMAGE-MGC_LOAD
NCBI Gene	619581	ENTREZGENE
PANTHER	NICOLIN-1	UniProtKB/TrEMBL
	PTHR31239	UniProtKB/TrEMBL
PhenoGen	Nicn1	PhenoGen
RatGTEx	ENSRNOG00000049083	RatGTEx
UniProt	A0A0G2JW73	ENTREZGENE, UniProtKB/TrEMBL
	A6I341_RAT	UniProtKB/TrEMBL
	Q3T1K9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-12-16	Nicn1	nicolin 1, tubulin polyglutamylase complex subunit	Nicn1	nicolin 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-19	Nicn1	nicolin 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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