Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Epb41l2 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of EPB41L2 mRNA | CTD | PMID:22206623 | Epb41l2 | Rat | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of EPB41L2 mRNA | CTD | PMID:25380136 | Epb41l2 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Ethinyl Estradiol results in increased expression of EPB41L2 mRNA | CTD | PMID:18936297 | Epb41l2 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Epb41l2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of EPB41L2 mRNA | CTD | PMID:17942748 | Epb41l2 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of EPB41L2 mRNA | CTD | PMID:17942748 | Epb41l2 | Rat | 17beta-estradiol | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Estradiol results in increased expression of EPB41L2 mRNA | CTD | PMID:23019147 | Epb41l2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of EPB41L2 mRNA | CTD | PMID:20106945 and PMID:21632981 | Epb41l2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of EPB41L2 mRNA | CTD | PMID:33387578 | Epb41l2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of EPB41L2 mRNA | CTD | PMID:21570461 | Epb41l2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Epb41l2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of EPB41L2 mRNA | CTD | PMID:17942748 | Epb41l2 | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of EPB41L2 mRNA | CTD | PMID:26251327 | Epb41l2 | Rat | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of EPB41L2 mRNA | CTD | PMID:25380136 | Epb41l2 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of EPB41L2 mRNA | CTD | PMID:30047161 | Epb41l2 | Rat | aflatoxin B1 | decreases methylation | ISO | EPB41L2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of EPB41L2 gene | CTD | PMID:27153756 | Epb41l2 | Rat | all-trans-retinoic acid | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of EPB41L2 mRNA | CTD | PMID:33167477 | Epb41l2 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of EPB41L2 mRNA | CTD | PMID:30047161 | Epb41l2 | Rat | aristolochic acid A | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of EPB41L2 mRNA | CTD | PMID:33212167 | Epb41l2 | Rat | Aroclor 1254 | decreases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of EPB41L2 mRNA | CTD | PMID:23650126 | Epb41l2 | Rat | arsane | decreases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Arsenic results in decreased expression of EPB41L2 mRNA | CTD | PMID:19654921 | Epb41l2 | Rat | arsenic atom | decreases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Arsenic results in decreased expression of EPB41L2 mRNA | CTD | PMID:19654921 | Epb41l2 | Rat | arsenous acid | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of EPB41L2 mRNA | CTD | PMID:15761015 | Epb41l2 | Rat | azathioprine | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Azathioprine results in decreased expression of EPB41L2 mRNA | CTD | PMID:22623647 | Epb41l2 | Rat | benzo[a]pyrene | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of EPB41L2 mRNA | CTD | PMID:20106945 and PMID:21632981 | Epb41l2 | Rat | benzo[a]pyrene | affects methylation | ISO | EPB41L2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of EPB41L2 5' UTR | CTD | PMID:27901495 | Epb41l2 | Rat | benzo[a]pyrene | decreases methylation | ISO | EPB41L2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of EPB41L2 3' UTR | CTD | PMID:27901495 | Epb41l2 | Rat | benzo[a]pyrene | decreases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of EPB41L2 mRNA | CTD | PMID:19770486 | Epb41l2 | Rat | beta-lapachone | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of EPB41L2 mRNA | CTD | PMID:38218311 | Epb41l2 | Rat | bisphenol A | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of EPB41L2 mRNA and bisphenol A results in increased expression of EPB41L2 protein | CTD | PMID:19371625 more ... | Epb41l2 | Rat | bisphenol A | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of EPB41L2 protein | CTD | PMID:31675489 | Epb41l2 | Rat | bisphenol A | decreases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of EPB41L2 mRNA | CTD | PMID:33221593 | Epb41l2 | Rat | bisphenol A | affects expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | bisphenol A affects the expression of EPB41L2 mRNA | CTD | PMID:30903817 | Epb41l2 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of EPB41L2 mRNA | CTD | PMID:30816183 | Epb41l2 | Rat | bisphenol A | affects methylation | ISO | Epb41l2 (Mus musculus) | 6480464 | bisphenol A affects the methylation of EPB41L2 promoter | CTD | PMID:27334623 | Epb41l2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of EPB41L2 mRNA | CTD | PMID:25181051 and PMID:34947998 | Epb41l2 | Rat | Bisphenol B | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of EPB41L2 protein | CTD | PMID:34186270 | Epb41l2 | Rat | cadmium dichloride | decreases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of EPB41L2 protein | CTD | PMID:16041627 | Epb41l2 | Rat | caffeine | affects phosphorylation | ISO | EPB41L2 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of EPB41L2 protein | CTD | PMID:35688186 | Epb41l2 | Rat | CGP 52608 | multiple interactions | ISO | EPB41L2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to EPB41L2 gene] | CTD | PMID:28238834 | Epb41l2 | Rat | cisplatin | multiple interactions | ISO | EPB41L2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of EPB41L2 mRNA and Cisplatin inhibits the reaction [Piroxicam results in decreased expression of EPB41L2 mRNA] | CTD | PMID:21858171 and PMID:27392435 | Epb41l2 | Rat | cisplatin | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of EPB41L2 mRNA | CTD | PMID:27392435 | Epb41l2 | Rat | clotrimazole | increases expression | EXP | | 6480464 | Clotrimazole results in increased expression of EPB41L2 mRNA | CTD | PMID:30047161 | Epb41l2 | Rat | copper atom | increases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Copper results in increased expression of EPB41L2 mRNA | CTD | PMID:16629173 | Epb41l2 | Rat | copper(0) | increases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Copper results in increased expression of EPB41L2 mRNA | CTD | PMID:16629173 | Epb41l2 | Rat | coumarin | affects phosphorylation | ISO | EPB41L2 (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of EPB41L2 protein | CTD | PMID:35688186 | Epb41l2 | Rat | coumestrol | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of EPB41L2 mRNA | CTD | PMID:19167446 | Epb41l2 | Rat | cyclophosphamide | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Cyclophosphamide results in decreased expression of EPB41L2 mRNA | CTD | PMID:17403535 | Epb41l2 | Rat | cyclosporin A | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of EPB41L2 mRNA | CTD | PMID:25562108 | Epb41l2 | Rat | deoxynivalenol | affects phosphorylation | ISO | Epb41l2 (Mus musculus) | 6480464 | deoxynivalenol affects the phosphorylation of EPB41L2 protein | CTD | PMID:23811945 | Epb41l2 | Rat | diarsenic trioxide | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of EPB41L2 mRNA | CTD | PMID:15761015 | Epb41l2 | Rat | Dibutyl phosphate | affects expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of EPB41L2 mRNA | CTD | PMID:37042841 | Epb41l2 | Rat | dibutyl phthalate | increases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of EPB41L2 mRNA | CTD | PMID:21266533 | Epb41l2 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of EPB41L2 mRNA | CTD | PMID:21266533 | Epb41l2 | Rat | dicrotophos | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of EPB41L2 mRNA | CTD | PMID:28302478 | Epb41l2 | Rat | diethylstilbestrol | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Diethylstilbestrol results in increased expression of EPB41L2 mRNA | CTD | PMID:19371625 | Epb41l2 | Rat | diquat | decreases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Diquat results in decreased expression of EPB41L2 mRNA | CTD | PMID:36851058 | Epb41l2 | Rat | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of EPB41L2 mRNA | CTD | PMID:25152437 | Epb41l2 | Rat | dorsomorphin | multiple interactions | ISO | EPB41L2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPB41L2 mRNA | CTD | PMID:27188386 | Epb41l2 | Rat | doxorubicin | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of EPB41L2 mRNA | CTD | PMID:29803840 | Epb41l2 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of EPB41L2 mRNA | CTD | PMID:29391264 | Epb41l2 | Rat | enzyme inhibitor | multiple interactions | ISO | EPB41L2 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of EPB41L2 protein | CTD | PMID:23301498 | Epb41l2 | Rat | ethanol | increases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Ethanol results in increased expression of EPB41L2 mRNA | CTD | PMID:30319688 | Epb41l2 | Rat | ethanol | multiple interactions | ISO | Epb41l2 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of EPB41L2 mRNA | CTD | PMID:30319688 | Epb41l2 | Rat | ethyl methanesulfonate | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of EPB41L2 mRNA | CTD | PMID:23649840 | Epb41l2 | Rat | FR900359 | affects phosphorylation | ISO | EPB41L2 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of EPB41L2 protein | CTD | PMID:37730182 | Epb41l2 | Rat | genistein | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Genistein results in increased expression of EPB41L2 mRNA | CTD | PMID:19371625 and PMID:23019147 | Epb41l2 | Rat | glyphosate | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Glyphosate results in increased expression of EPB41L2 mRNA | CTD | PMID:17984146 | Epb41l2 | Rat | ivermectin | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of EPB41L2 protein | CTD | PMID:32959892 | Epb41l2 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of EPB41L2 mRNA | CTD | PMID:30047161 | Epb41l2 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of EPB41L2 gene | CTD | PMID:35440735 | Epb41l2 | Rat | methyl methanesulfonate | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of EPB41L2 mRNA | CTD | PMID:23649840 | Epb41l2 | Rat | methylseleninic acid | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | methylselenic acid results in increased expression of EPB41L2 mRNA | CTD | PMID:18548127 | Epb41l2 | Rat | mitoxantrone | affects response to substance | ISO | EPB41L2 (Homo sapiens) | 6480464 | EPB41L2 mRNA affects the susceptibility to Mitoxantrone | CTD | PMID:16044152 | Epb41l2 | Rat | N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of EPB41L2 mRNA | CTD | PMID:25380136 | Epb41l2 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of EPB41L2 mRNA | CTD | PMID:25729387 | Epb41l2 | Rat | ozone | multiple interactions | ISO | Epb41l2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of EPB41L2 mRNA | CTD | PMID:34911549 | Epb41l2 | Rat | pirinixic acid | decreases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of EPB41L2 mRNA | CTD | PMID:17426115 | Epb41l2 | Rat | piroxicam | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Piroxicam results in decreased expression of EPB41L2 mRNA | CTD | PMID:21858171 | Epb41l2 | Rat | piroxicam | multiple interactions | ISO | EPB41L2 (Homo sapiens) | 6480464 | Cisplatin inhibits the reaction [Piroxicam results in decreased expression of EPB41L2 mRNA] | CTD | PMID:21858171 | Epb41l2 | Rat | resveratrol | increases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | resveratrol results in increased expression of EPB41L2 protein | CTD | PMID:25505154 | Epb41l2 | Rat | resveratrol | multiple interactions | ISO | EPB41L2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of EPB41L2 mRNA | CTD | PMID:23557933 | Epb41l2 | Rat | SB 431542 | multiple interactions | ISO | EPB41L2 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | Epb41l2 | Rat | silicon dioxide | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of EPB41L2 mRNA and Silicon Dioxide results in increased expression of EPB41L2 mRNA | CTD | PMID:25351596 and PMID:25895662 | Epb41l2 | Rat | sodium arsenite | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of EPB41L2 mRNA | CTD | PMID:38568856 | Epb41l2 | Rat | sodium fluoride | decreases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Sodium Fluoride results in decreased expression of EPB41L2 mRNA | CTD | PMID:27862939 | Epb41l2 | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of EPB41L2 mRNA | CTD | PMID:19281266 | Epb41l2 | Rat | succimer | multiple interactions | ISO | Epb41l2 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of EPB41L2 mRNA | CTD | PMID:21641980 | Epb41l2 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of EPB41L2 mRNA | CTD | PMID:30047161 | Epb41l2 | Rat | T-2 toxin | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | T-2 Toxin results in decreased expression of EPB41L2 mRNA | CTD | PMID:34581912 | Epb41l2 | Rat | tamoxifen | affects expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Tamoxifen affects the expression of EPB41L2 mRNA | CTD | PMID:14699072 | Epb41l2 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of EPB41L2 mRNA | CTD | PMID:15336504 | Epb41l2 | Rat | tetrachloromethane | decreases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of EPB41L2 mRNA | CTD | PMID:17484886 | Epb41l2 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of EPB41L2 mRNA | CTD | PMID:34492290 | Epb41l2 | Rat | titanium dioxide | increases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of EPB41L2 mRNA | CTD | PMID:29264374 | Epb41l2 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of EPB41L2 mRNA | CTD | PMID:25729387 | Epb41l2 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of EPB41L2 mRNA | CTD | PMID:33387578 | Epb41l2 | Rat | trichostatin A | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of EPB41L2 mRNA | CTD | PMID:26272509 | Epb41l2 | Rat | trichostatin A | multiple interactions | ISO | EPB41L2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPB41L2 mRNA | CTD | PMID:27188386 | Epb41l2 | Rat | triclosan | decreases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of EPB41L2 mRNA | CTD | PMID:30510588 | Epb41l2 | Rat | triphenyl phosphate | affects expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of EPB41L2 mRNA | CTD | PMID:37042841 | Epb41l2 | Rat | tungsten | decreases expression | ISO | Epb41l2 (Mus musculus) | 6480464 | Tungsten results in decreased expression of EPB41L2 mRNA | CTD | PMID:30912803 | Epb41l2 | Rat | valproic acid | affects expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of EPB41L2 mRNA | CTD | PMID:25979313 | Epb41l2 | Rat | valproic acid | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of EPB41L2 mRNA | CTD | PMID:29154799 | Epb41l2 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of EPB41L2 mRNA | CTD | PMID:19015723 | Epb41l2 | Rat | vitamin E | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of EPB41L2 mRNA | CTD | PMID:19244175 | Epb41l2 | Rat | vorinostat | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | vorinostat results in increased expression of EPB41L2 mRNA | CTD | PMID:27188386 | Epb41l2 | Rat | zearalenone | increases expression | ISO | EPB41L2 (Homo sapiens) | 6480464 | Zearalenone results in increased expression of EPB41L2 mRNA | CTD | PMID:19371625 | |