Gpr34 (G protein-coupled receptor 34)

Gene: Gpr34 (G protein-coupled receptor 34) Rattus norvegicus

Analyze

Symbol:

Gpr34

Name:

G protein-coupled receptor 34

RGD ID:

1563681

Description:

Predicted to enable G protein-coupled purinergic nucleotide receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Orthologous to human GPR34 (G protein-coupled receptor 34); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

G-protein-coupled receptor GPR34; probable G-protein coupled receptor 34

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GPR34 (G protein-coupled receptor 34)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, PhylomeDB, Treefam
Mus musculus (house mouse):	Gpr34 (G protein-coupled receptor 34)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gpr34 (G protein-coupled receptor 34)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GPR34 (G protein-coupled receptor 34)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GPR34 (G protein-coupled receptor 34)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gpr34 (G protein-coupled receptor 34)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GPR34 (G protein-coupled receptor 34)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GPR34 (G protein-coupled receptor 34)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gpr34 (G protein-coupled receptor 34)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	GPR34 (G protein-coupled receptor 34)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gpr34 (G protein-coupled receptor 34)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gpr34a (G protein-coupled receptor 34a)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)
Danio rerio (zebrafish):	gpr34b (G protein-coupled receptor 34b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	gpr34	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	11,777,667 - 11,786,640 (-)	NCBI		GRCr8
mRatBN7.2	X	9,104,829 - 9,113,796 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	9,104,565 - 9,148,601 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	9,290,159 - 9,297,836 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	12,787,294 - 12,794,971 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	9,059,046 - 9,066,723 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	10,022,986 - 10,043,504 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	10,023,489 - 10,031,167 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	10,820,883 - 10,841,190 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	21,117,225 - 21,124,903 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	9,644,793 - 9,652,471 (-)	NCBI		Celera
Cytogenetic Map	X	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

ovarian cyst (ISO)

syndromic X-linked intellectual disability Hedera type (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

syndromic X-linked intellectual disability Najm type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

all-trans-retinoic acid (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroprene (ISO)

dimethylarsinic acid (ISO)

furan (EXP)

genistein (EXP)

hydrogen peroxide (ISO)

iron atom (ISO)

iron(0) (ISO)

lidocaine (EXP)

lipopolysaccharide (ISO)

manganese atom (EXP)

manganese(0) (EXP)

manganese(II) chloride (EXP)

medroxyprogesterone acetate (ISO)

methylarsonic acid (ISO)

ozone (ISO)

perfluorohexanesulfonic acid (ISO)

potassium dichromate (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

testosterone (EXP)

titanium dioxide (EXP,ISO)

trovafloxacin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

G protein-coupled purinergic nucleotide receptor signaling pathway (IEA)

G protein-coupled receptor signaling pathway (IBA)

Cellular Component

plasma membrane (IEA)

Molecular Function

G protein-coupled purinergic nucleotide receptor activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	The structural evolution of a P2Y-like G-protein-coupled receptor.	Schulz A and Schoneberg T, J Biol Chem 2003 Sep 12;278(37):35531-41. Epub 2003 Jun 30.

Additional References at PubMed

PMID:12511555	PMID:14960569	PMID:16460680	PMID:22343749

Genomics

Comparative Map Data

Gpr34
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	11,777,667 - 11,786,640 (-)	NCBI		GRCr8
mRatBN7.2	X	9,104,829 - 9,113,796 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	9,104,565 - 9,148,601 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	9,290,159 - 9,297,836 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	12,787,294 - 12,794,971 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	9,059,046 - 9,066,723 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	10,022,986 - 10,043,504 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	10,023,489 - 10,031,167 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	10,820,883 - 10,841,190 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	21,117,225 - 21,124,903 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	9,644,793 - 9,652,471 (-)	NCBI		Celera
Cytogenetic Map	X	q12	NCBI

GPR34
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	41,688,973 - 41,697,275 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	41,688,973 - 41,697,275 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	41,548,226 - 41,556,528 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	41,433,170 - 41,441,474 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	41,304,512 - 41,312,780	NCBI
Celera	X	45,690,450 - 45,698,755 (+)	NCBI		Celera
Cytogenetic Map	X	p11.4	NCBI
HuRef	X	39,279,235 - 39,287,712 (+)	NCBI		HuRef
CHM1_1	X	41,580,698 - 41,589,003 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	41,093,901 - 41,102,205 (+)	NCBI		T2T-CHM13v2.0

Gpr34
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	13,489,777 - 13,507,098 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	13,498,328 - 13,507,097 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	13,622,650 - 13,640,859 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	13,632,089 - 13,640,858 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	13,209,895 - 13,217,984 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	12,789,750 - 12,797,796 (+)	NCBI		MGSCv36	mm8
Celera	X	11,302,257 - 11,310,346 (+)	NCBI		Celera
Cytogenetic Map	X	A1.1	NCBI
cM Map	X	8.55	NCBI

Gpr34
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955565	1,096,853 - 1,103,610 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955565	1,096,853 - 1,103,610 (-)	NCBI	ChiLan1.0	ChiLan1.0

GPR34
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	43,330,805 - 43,347,977 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	43,338,624 - 43,349,757 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	34,136,375 - 34,145,754 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	41,830,125 - 41,838,336 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	41,836,693 - 41,837,838 (+)	Ensembl	panpan1.1		panPan2

GPR34
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	36,080,912 - 36,087,759 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	23,428,720 - 23,435,676 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	36,162,479 - 36,169,440 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	X	36,208,871 - 36,215,832 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	36,187,128 - 36,194,089 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	36,224,804 - 36,231,765 (+)	NCBI		UU_Cfam_GSD_1.0

Gpr34
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	28,229,998 - 28,237,522 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936502	8,076,590 - 8,077,714 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936502	8,070,824 - 8,078,273 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPR34
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	37,306,509 - 37,313,923 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	37,306,490 - 37,313,626 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	41,532,877 - 41,541,103 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GPR34
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	38,887,666 - 38,897,066 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	38,895,425 - 38,896,567 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666076	4,053,208 - 4,061,888 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gpr34
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624762	13,934,377 - 13,941,445 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gpr34
12 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	74
Count of miRNA genes:	58
Interacting mature miRNAs:	65
Transcripts:	ENSRNOT00000060988
Prediction methods:	Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
731181	Uae27	Urinary albumin excretion QTL 27	2.7	0.0059	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	X	1	43491017	Rat
70166	Bp65	Blood pressure QTL 65	5.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	X	1447972	11374346	Rat
634325	Bw13	Body weight QTL 13	0		body mass (VT:0001259)	body weight (CMO:0000012)	X	1447972	20991088	Rat
70165	Bp64	Blood pressure QTL 64	5.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	X	1448129	31706553	Rat
631204	Gluco15	Glucose level QTL 15		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	X	1623715	22646544	Rat
1298071	Edpm12	Estrogen-dependent pituitary mass QTL 12	3.2		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	X	2927898	47927898	Rat
10755455	Coatc13	Coat color QTL 13		0	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	7	4406000	49406000	Rat
631666	Iddm5	Insulin dependent diabetes mellitus QTL 5			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	X	4494549	49494549	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			6		17				26		5	1
Low	3	33	46	36	2	36	8	10	46	34	35	10	8
Below cutoff		8	4	4		4		1	2	1	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001024925	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006256675	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006256676	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039099999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB159443	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY241083	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000060988 ⟹ ENSRNOP00000057707

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	9,105,126 - 9,148,601 (-)	Ensembl
Rnor_6.0 Ensembl	X	10,023,489 - 10,031,167 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000097428 ⟹ ENSRNOP00000093134

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	9,104,565 - 9,125,195 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099018 ⟹ ENSRNOP00000080963

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	9,104,565 - 9,113,960 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000106478 ⟹ ENSRNOP00000080929

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	9,104,565 - 9,113,732 (-)	Ensembl

RefSeq Acc Id:

NM_001024925 ⟹ NP_001020096

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	11,778,158 - 11,785,836 (-)	NCBI
mRatBN7.2	X	9,105,332 - 9,113,010 (-)	NCBI
Rnor_6.0	X	10,023,489 - 10,031,167 (-)	NCBI
Rnor_5.0	X	10,820,883 - 10,841,190 (-)	NCBI
RGSC_v3.4	X	21,117,225 - 21,124,903 (-)	RGD
Celera	X	9,644,793 - 9,652,471 (-)	RGD

Sequence:

show sequence

TTCAGCAAAGCCTCAACTCAGTTCCTGTGACTTCTGAAGTATGGCCTGAATAGATTCAATCATT
ATTAGTCCATTATCATATAGGAAAATCTGAAGACACCAAGAAGTATAAAAAGCATGTCATTTAG
CACCCTGTCCTGATAGTTACAGAAGACATTGAGAAGTTACAGTGTAACAATGACGACTACAGTT
GACAGCTGGCTTTGCTCCTCTCCTGGAATGCACTTTATAACTAATGACAGTGACCAAGTCTCAC
AAAATTTCTCAGGAGTGTCAAATGTCACTAGCTGTCCAATGGATGAAAAATTACTGTCTACTGT
GTTAACAACTTTCTACTCTGTGATATTCATCGTGGGACTGGTTGGAAACATCATTGCCCTTTAT
GTATTTCTGGGCATCCACCGCAAAAGAAATTCCATTCAAATTTATCTACTTAATGTGGCTGTTG
CAGACCTTCTACTCATCTTCTGCCTCCCTTTCCGCATAATGTATCACATCAACCAAAATAGGTG
GACACTAGGTGTGATTCTTTGCAAAGTTGTGGGGACACTATTTTACATGAACATGTACATTAGT
ATTATTCTGCTTGGGTTTATCAGTTTGGATCGATATATAAAAATCAACCGGTCTATACAACAAA
GAAGGGCAATAACCACCAAGCAAAGTGTTTACGTTTGCTGTGTAGTCTGGACAGTTGCTCTAGC
TGGATTTTTAACAATGATCATTTTGACACTGAAGAAGGGAGGGCACAATTCCACAATGTGTTTC
CATTACAGAGATAAGCATAATGCAAAGGGAGAAGCGATCTTTAACTTTGCTCTTGTAGTAATGT
TCTGGCTCATTTTCCTACTGATAATCCTTTCATATATTAAGATTGGCAAGAATCTACTGAGGAT
TTCTAAAAGGAGGTCAAAATTTCCTAACTCTGGCAAATATGCCACGACAGCCCGGAACTCCTTC
ATTGTACTAATCATTTTTACTATATGCTTCGTGCCTTATCATGCCTTTCGATTCATTTACATTT
CTTCACAGCTAAATGCATCTTCTTGCTACTGGAAGGAAATCATTCATAAAACCAATGAGATCAT
GTTGGTTCTCTCCTCTTTCAACAGCTGCTTGGATCCTGTCATGTATTTCCTAATGTCCAGTAAT
ATTCGCAAAATCATGTGTCAACTTCTTTTTAGAAGATTTCAAAGTGACACAAGCAGAAGTGAAA
GCACTTCAGAATTTAAGCCAGGATATTCCTTGCATGATCTATCTGTGACGGTCAAAATGCAGTA
CAGCACTAAGGGTAACTGA

hide sequence

RefSeq Acc Id:

XM_006256675 ⟹ XP_006256737

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	11,777,667 - 11,786,640 (-)	NCBI
mRatBN7.2	X	9,104,829 - 9,113,796 (-)	NCBI
Rnor_6.0	X	10,022,986 - 10,034,261 (-)	NCBI
Rnor_5.0	X	10,820,883 - 10,841,190 (-)	NCBI

Sequence:

show sequence

TATAATTGTTAGAATCCAAAACCATCACCCAGCAGCTTTTCTCACATAATTGATCCATGTAAGA
ATTACTAAGGATGCTGACTAGATGGGCAAAGTTTGAAGAGTGACAGGATACTTATACATTCTCA
AAGTACCATCCTACAGGATACTTACTAATTACAAAATGGAATGGTAATATTTCAAGGGAGAAGC
CTAGAACAAAGTAGCCCAGAGAACAAAGCAAATAATGGGACTAGGCAATAATCCATCATCTTGA
TATGATGCATTGAGAAGCCAGACACACTGTCACGGTACCCTTGGCAATTAGATCTAGCAATGCC
CAAGAAGCATTCTAGAAAGTAGCAGGCTTATGCTCTTCAAAACTAGCCCTGGACTCAAGGGTTT
CAGGGAAACTAAAGGAGTATCACAGATAAATGTGATCATCTTATTATTTTTTGCTCTAGAAAGT
ATTAGGGCAGTTGATGAAATTTATAACAAGGATTGTCAAATATATTCTTTTAATGTAAATTTCC
TGATTTTGATTACTGCACTGTATAGTGTAGCTTTTTTTAAGTCTAAAAGTATGTCCCGAACCTG
CCCTTCCCATCCTATTTTAAAGGAACCTAAAATAGCTTTTCATGTGGTTATGCTTTTATTTTGT
CATATAATAAGGCTTATTTAGTTTAATTAGATTTGTACAGTTTGGTAATTACAGAAAACATGCC
TGTACTTCCAAATTCAGAACTGCAAAACAAATTATATTCAGAGGTCTAGTTTTCCTTTTCTTTT
ATTATGCTTCAATATCTCCCACCTTATTTGGAAGATTAAAACTAAGAAATAAAATGCATAGAAA
AATGCATATGTTTCCTGTAATGTGCCCTGTAGCTATGGAGGAGGTTCCTTTCTAAGTGTTTCTG
CTTTCTTAGGGAAATGAAAAGGAACTTCTAGGTGAGAGTGGGGAAGGAAATGGGGTAGCTGTCA
GTTTGAGAAGGTTGAAGGTGTGAAACACTATTTTTTAGGGAGGATGAACTAGGGTAATGGCGGT
TACATTTAAAACCAGAGTCACACAGACTGTTGGCCCTCATACCCAGATTTTCTGCTTGGGTCTG
GATGAGCTTAGAGTATACCTCAGTTGCAAGCTTCTGAATGTTTTTGACGTTAGTGGTCTGGAAG
TCATCTTTTGAGAATTACTGGGCTAAGGACATTAGAATTCACTCTAAGGAGTTCTGGCAGTGCA
GGGGACCCTTAAGGTTTCTGATTGGCAATCTGAAGACAGGCTACTGTGTCTGATTGAGTGCTTG
TACCCAGCCAGCAATCCTCATCTTCACTGTGGAGGTTCGGGACTGGAGGAGGTGGGAAGCTGAA
CTTCACTAGGGTTGGGTTTCACATAAAGAGGGGATGGTGACAAAGTTCAGAATGATCAGGAACT
AGGAAATAATACTCAAACCTTACATCAACAAGAAGATGTGACTACAATATGAGAACCCTAAAGC
TGAAAAACACAATTTTGAAATGGGGTGGCATAAGCGTGGGACAACAGTACAATACAAAAATAGT
ATTTCAGTAGATAAACAGCACTTCATGACTCATTTAGTCATGAAAATCCTGCCAGAATTTTAGA
GATATCTGCATATTCCTGCTTGTTGTAGCGATATTCATAATTGCCTGTGAGTGGAGATAACGTA
CATGTTTATTGAAAGATGATAAAGACAATTAAATATAGGCAAACAATGGAAATGTGCAGCCTTA
AAAACAAAGGAAACTATATTACATGCTATAGCTTGGGTGAACCTCAAGGATACTAGGCTAAATA
AAATTAACTAGTCACAAAAAGGTTGTATAATTTGACTCAATGTCCCAGAATCATGGTTGCTAAT
GTTGGGAATAGGGGCAGAGAAAATTTGTATGCCGTAGGTTTAGAGGTTTAATTTTGCAACACGA
AAATGTTACGGTGAAGTGCTGCATGATGACAGAAGTACACTGAGCACCACTGCATGACAGACTC
AAAACTGGCTATGTGGTAAATCTAGTGGTATGTGTCGCTTACCACAGTAAGACAAAAACATGCT
GCCGGACAAATACAGTAACCGTCTTCCTTCTCAAAGATTCTTAGGGGGAAGTAAGCATTCTAAA
ATATTTTTATTGTAACAATATAAAATTATGGTCTCATATATTATGACTCTTAAACAAACTAAAC
TAAAAGCTCTGGAGAATATGAGGTTCAGAAGAACATTCCCAGAAATACAATGTTAGATGAAGCC
CAGGGAGTTAAATATTATTTAAACAAGGCTGCAAAGCTAGAGAATGACAATCATATTCTAAACA
ACAACCAAAAGGGGAAATGACACTCAAGTGCAGGGCCAGCAGTTACAAAAGAACCGATGGGGGT
TAAATAGTGAACTGGGCCAGAATGGACGCTGCAGAGCCTCATCATACTTTCCTTGAAATAGGAC
AGAGCACCCCGGCCTACTTGGCTCCAAACGGGGCCCAAGGGCTGTCACACTGAAAAAAGAAAGA
AAAGGGGAAAAACAACTGTACCACATGTGAATATAAAAAAGAAGAGAACTCTAGCCAATTGCAC
CAGCACCGGATGGAAGAGTCCAGCTGACACGACCTGGTCGAGGGAGCTTTGGGTTTCCTCCTTT
ACTTCAGCAAAGCCTCAACTCAGTTCCTGTGACTTCTGAAGTATGGCCTGAATAGATTCAATCA
TTATTAGTCCATTATCATATAGGAAAATCTGAAGACACCAAGAAGTATAAAGAGCATGTCATTT
AGCACCCTGTCCTGATAGTTACAGAAGACATTGAGAAGTTACAGTGTAACAATGACGACTACAG
TTGACAGCTGGCTTTGCTCCTCTCCTGGAATGCACTTTATAACTAATGACAGTGACCAAGTCTC
ACAAAATTTCTCAGGAGTGTCAAATGTCACTAGCTGTCCAATGGATGAAAAATTACTGTCTACT
GTGTTAACAACTTTCTACTCTGTGATATTCATCGTGGGACTGGTTGGAAACATCATTGCCCTTT
ATGTATTTCTGGGCATCCACCGCAAAAGAAATTCCATTCAAATTTATCTACTTAATGTGGCTGT
TGCAGACCTTCTACTCATCTTCTGCCTCCCTTTCCGCATAATGTATCACATCAACCAAAATAGG
TGGACACTAGGTGTGATTCTTTGCAAAGTTGTGGGGACACTATTTTACATGAACATGTACATTA
GTATTATTCTGCTTGGGTTTATCAGTTTGGATCGATATATAAAAATCAACCGGTCTATACAACA
AAGAAGGGCAATAACCACCAAGCAAAGTGTTTACGTTTGCTGTGTAGTCTGGACAGTTGCTCTA
GCTGGATTTTTAACAATGATCATTTTGACACTGAAGAAGGGAGGGCACAATTCCACAATGTGTT
TCCATTACAGAGATAAGCATAATGCAAAGGGAGAAGCGATCTTTAACTTTGCTCTTGTAGTAAT
GTTCTGGCTCATTTTCCTACTGATAATCCTTTCATATATTAAGATTGGCAAGAATCTACTGAGG
ATTTCTAAAAGGAGGTCAAAATTTCCTAACTCTGGCAAATATGCCACGACAGCCCGGAACTCCT
TCATTGTACTAATCATTTTTACTATATGCTTCGTGCCTTATCATGCCTTTCGATTCATTTACAT
TTCTTCACAGCTAAATGCGTCTTCTTGCTACTGGAAGGAAATCATTCATAAAACCAATGAGATC
ATGTTGGTTCTCTCCTCTTTCAACAGCTGCTTGGATCCTGTCATGTATTTCCTAATGTCCAGTA
ATATTCGCAAAATCATGTGTCAACTTCTTTTTAGAAGATTTCAAAGTGACACAAGCAGAAGTGA
AAGCACTTCAGAATTTAAGCCAGGATATTCCTTGCATGATCTATCTGTGACGGTCAAAATGCAG
TACAGCACTAAGGGTAACTGAGGCACATGCAGTAAAATGAACAACATAAACCAGCCTCTTCATT
CCTTGAGGTTGGTAAAATTATGGAACAAATTCCTAGCATGTTCAAAAACCAGATCTTTAGAAGT
GGTCTTTCACTTGCTTAACTGCAAAATAGTTCAAGGCAAAGAAAAGCTTACACTAATCCCTAGA
TTTTAGAACTATATGTAGAATCTTCACAGAATACATTGTTAAGCTAACACTTTTAACAATGGTT
ATAATGTTAAGTGAAGTTCATGGAATTAACAACGAAATGGATGAAATGTCATTGTTTCCTGAAG
TCACTAAAGAATTACTAAAGTTAGAAACTTGATACTAATTTTAAATATGTTTAAAATTAAGTAA
TTTGGGGACTGAGTTGAAATGTCAGTAAACATGAGTATTACTTCAAAATCTTACATCACTTGAT
GCTATATTCATTTATGTCTAAATCTCTGCTAACAGATGAAATAATAAAATTCTAATAAAAGTGA
GATTGCCCACTA

hide sequence

RefSeq Acc Id:

XM_039099999 ⟹ XP_038955927

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	11,777,667 - 11,786,634 (-)	NCBI
mRatBN7.2	X	9,104,829 - 9,113,796 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001020096	(Get FASTA)	NCBI Sequence Viewer
	XP_006256737	(Get FASTA)	NCBI Sequence Viewer
	XP_038955927	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAP04292	(Get FASTA)	NCBI Sequence Viewer
	BAE80685	(Get FASTA)	NCBI Sequence Viewer
	EDL97660	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000057707.2
	ENSRNOP00000080929
	ENSRNOP00000080929.1
	ENSRNOP00000080963
	ENSRNOP00000080963.1
	ENSRNOP00000093134.1

RefSeq Acc Id:

NP_001020096 ⟸ NM_001024925

- UniProtKB:

Q6XCE7 (UniProtKB/TrEMBL), A6JZX9 (UniProtKB/TrEMBL), A0A8I6AI22 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTTTVDSWLCSSPGMHFITNDSDQVSQNFSGVSNVTSCPMDEKLLSTVLTTFYSVIFIVGLVGN
IIALYVFLGIHRKRNSIQIYLLNVAVADLLLIFCLPFRIMYHINQNRWTLGVILCKVVGTLFYM
NMYISIILLGFISLDRYIKINRSIQQRRAITTKQSVYVCCVVWTVALAGFLTMIILTLKKGGHN
STMCFHYRDKHNAKGEAIFNFALVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATT
ARNSFIVLIIFTICFVPYHAFRFIYISSQLNASSCYWKEIIHKTNEIMLVLSSFNSCLDPVMYF
LMSSNIRKIMCQLLFRRFQSDTSRSESTSEFKPGYSLHDLSVTVKMQYSTKGN

hide sequence

RefSeq Acc Id:	XP_006256737 ⟸ XM_006256675
- Peptide Label:	isoform X1
- UniProtKB:	Q6XCE7 (UniProtKB/TrEMBL), A6JZX9 (UniProtKB/TrEMBL), A0A8I6AI22 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTTTVDSWLCSSPGMHFITNDSDQVSQNFSGVSNVTSCPMDEKLLSTVLTTFYSVIFIVGLVGN IIALYVFLGIHRKRNSIQIYLLNVAVADLLLIFCLPFRIMYHINQNRWTLGVILCKVVGTLFYM NMYISIILLGFISLDRYIKINRSIQQRRAITTKQSVYVCCVVWTVALAGFLTMIILTLKKGGHN STMCFHYRDKHNAKGEAIFNFALVVMFWLIFLLIILSYIKIGKNLLRISKRRSKFPNSGKYATT ARNSFIVLIIFTICFVPYHAFRFIYISSQLNASSCYWKEIIHKTNEIMLVLSSFNSCLDPVMYF LMSSNIRKIMCQLLFRRFQSDTSRSESTSEFKPGYSLHDLSVTVKMQYSTKGN hide sequence

RefSeq Acc Id:

ENSRNOP00000057707 ⟸ ENSRNOT00000060988

RefSeq Acc Id:	XP_038955927 ⟸ XM_039099999
- Peptide Label:	isoform X1
- UniProtKB:	Q6XCE7 (UniProtKB/TrEMBL), A6JZX9 (UniProtKB/TrEMBL), A0A8I6AI22 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000080929 ⟸ ENSRNOT00000106478

RefSeq Acc Id:

ENSRNOP00000080963 ⟸ ENSRNOT00000099018

RefSeq Acc Id:

ENSRNOP00000093134 ⟸ ENSRNOT00000097428

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6XCE7-F1-model_v2	AlphaFold	Q6XCE7	1-373	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563681	AgrOrtholog
BioCyc Gene	G2FUF-3094	BioCyc
Ensembl Genes	ENSRNOG00000039759	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000060988.3	UniProtKB/TrEMBL
	ENSRNOT00000097428.1	UniProtKB/TrEMBL
	ENSRNOT00000099018.1	UniProtKB/TrEMBL
	ENSRNOT00000106478	ENTREZGENE
	ENSRNOT00000106478.1	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	7TM_GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_supfam	UniProtKB/TrEMBL
	GPR34_7tmA	UniProtKB/TrEMBL
KEGG Report	rno:554353	UniProtKB/TrEMBL
NCBI Gene	554353	ENTREZGENE
PANTHER	G-PROTEIN COUPLED RECEPTOR 34-RELATED	UniProtKB/TrEMBL
	P2Y PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PhenoGen	Gpr34	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
	P2YPURNOCPTR	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000039759	RatGTEx
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A8I6AI22	ENTREZGENE, UniProtKB/TrEMBL
	A6JZX9	ENTREZGENE
	Q6XCE7	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	A6JZX9	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-04	Gpr34	G protein-coupled receptor 34	GPR34_predicted	G-protein-coupled receptor GPR34 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	GPR34_predicted	G-protein-coupled receptor GPR34 (predicted)	GPR34	G-protein-coupled receptor GPR34	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	GPR34	G-protein-coupled receptor GPR34			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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