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Gene: Capzb (capping actin protein of muscle Z-line subunit beta) Rattus norvegicus

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Symbol:

Capzb

Name:

capping actin protein of muscle Z-line subunit beta

RGD ID:

1359099

Description:

Predicted to enable actin filament binding activity. Predicted to be involved in several processes, including barbed-end actin filament capping; regulation of cell morphogenesis; and regulation of plasma membrane bounded cell projection assembly. Predicted to act upstream of or within actin polymerization or depolymerization and lamellipodium assembly. Located in dendritic spine and neuronal cell body. Biomarker of dementia. Orthologous to human CAPZB (capping actin protein of muscle Z-line subunit beta); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

capping actin protein of muscle Z-line beta subunit; capping protein (actin filament) muscle Z-line, beta; capZ beta; F-actin capping protein beta subunit; F-actin-capping protein subunit beta; MGC95097

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	156,718,619 - 156,818,623 (+)	NCBI		GRCr8
mRatBN7.2	5	151,435,600 - 151,535,409 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	151,434,871 - 151,535,409 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	154,133,022 - 154,233,265 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	155,907,343 - 156,007,613 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	155,888,276 - 155,988,134 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	157,642,742 - 157,742,487 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	157,642,751 - 157,742,478 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	161,383,315 - 161,482,718 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	157,980,877 - 158,080,682 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	157,990,915 - 158,090,719 (+)	NCBI
Celera	5	149,816,061 - 149,915,748 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3-hydroxy-3-methylglutaryl-CoA lyase deficiency (ISO)

Acute Coronary Syndrome (ISO)

Animal Mammary Neoplasms (ISO)

carcinoma (ISO)

chromosome 1p36 deletion syndrome (ISO)

congenital disorder of glycosylation Ir (ISO)

dementia (IEP)

Experimental Mammary Neoplasms (ISO)

hyperprolinemia type 2 (ISO)

Parkinson's disease 6 (ISO)

Spinal Cord Injuries (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

4-hydroxynon-2-enal (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (EXP)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

choline (ISO)

cisplatin (ISO)

clofibrate (ISO)

cocaine (ISO)

CU-O LINKAGE (ISO)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fenthion (ISO)

fluorescein 5-isothiocyanate (ISO)

folic acid (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

ivermectin (ISO)

L-methionine (ISO)

mercury atom (ISO)

mercury(0) (ISO)

methamphetamine (ISO)

methapyrilene (ISO)

methidathion (ISO)

methimazole (EXP)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

microcystin-LR (ISO)

Nonylphenol (EXP)

ochratoxin A (ISO)

paracetamol (EXP,ISO)

phenobarbital (EXP)

resveratrol (ISO)

SB 431542 (ISO)

selenium atom (ISO)

sevoflurane (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

thapsigargin (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin cytoskeleton organization (IEA)

actin polymerization or depolymerization (IEA,ISO)

barbed-end actin filament capping (IBA,IEA)

biological_process (ND)

cell morphogenesis (IBA)

cell projection organization (ISO)

cytoskeleton organization (ISO,ISS)

lamellipodium assembly (IEA,ISO)

negative regulation of filopodium assembly (IBA)

regulation of cell morphogenesis (IEA,ISO,ISS)

regulation of lamellipodium assembly (IBA)

Cellular Component

asymmetric synapse (ISO)

brush border (IEA,ISO)

cortical cytoskeleton (IEA,ISO)

dendritic spine (IDA)

F-actin capping protein complex (IBA,IEA)

hippocampal mossy fiber to CA3 synapse (IEA,ISO)

lamellipodium (IEA,ISO)

membrane (IEA,ISO)

neuronal cell body (IDA)

postsynaptic density (IEA,ISO)

sarcomere (IEA)

Schaffer collateral - CA1 synapse (IEA,ISO)

sperm head-tail coupling apparatus (IEA,ISO)

WASH complex (IEA,ISO,ISS)

Molecular Function

actin binding (IEA,ISO,ISS)

actin filament binding (IBA)

protein binding (IPI,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Differential protein levels and post-translational modifications in spinal cord injury of the rat.	Afjehi-Sadat L, etal., J Proteome Res. 2010 Mar 5;9(3):1591-7. doi: 10.1021/pr901049a.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Vertebrate isoforms of actin capping protein beta have distinct functions In vivo.	Hart MC and Cooper JA, J Cell Biol 1999 Dec 13;147(6):1287-98.
5.	Activity-dependent localization in spines of the F-actin capping protein CapZ screened in a rat model of dementia.	Kitanishi T, etal., Genes Cells. 2010 Jun;15(7):737-47. doi: 10.1111/j.1365-2443.2010.01411.x. Epub 2010 Jun 10.
6.	Intracellular cAMP controls a physical association of V-1 with CapZ in cultured mammalian endocrine cells.	Kitazawa M, etal., Biochem Biophys Res Commun. 2005 May 27;331(1):181-6.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	GOA pipeline	RGD automated data pipeline
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Comprehensive gene review and curation	RGD comprehensive gene curation
11.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11604420	PMID:12089068	PMID:15294161	PMID:17656356	PMID:18076569	PMID:18272787	PMID:18723693	PMID:19056867	PMID:19199708	PMID:19267422	PMID:19295171	PMID:19341723
PMID:19806181	PMID:19922875	PMID:20458337	PMID:20884878	PMID:21834987	PMID:22114352	PMID:22871113	PMID:23376485	PMID:23493359	PMID:23533145	PMID:24043251	PMID:24093776
PMID:24625528	PMID:25468996	PMID:25810514	PMID:26237647	PMID:26429793	PMID:27185186	PMID:28493397	PMID:29476059	PMID:30026308	PMID:30053369	PMID:35352799

Genomics

Comparative Map Data

Capzb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	156,718,619 - 156,818,623 (+)	NCBI		GRCr8
mRatBN7.2	5	151,435,600 - 151,535,409 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	151,434,871 - 151,535,409 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	154,133,022 - 154,233,265 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	155,907,343 - 156,007,613 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	155,888,276 - 155,988,134 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	157,642,742 - 157,742,487 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	157,642,751 - 157,742,478 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	161,383,315 - 161,482,718 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	157,980,877 - 158,080,682 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	157,990,915 - 158,090,719 (+)	NCBI
Celera	5	149,816,061 - 149,915,748 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

CAPZB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	19,338,775 - 19,485,539 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	19,338,775 - 19,485,539 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	19,665,269 - 19,812,033 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	19,537,860 - 19,684,579 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	19,411,069 - 19,491,551	NCBI
Celera	1	17,992,290 - 18,138,980 (-)	NCBI		Celera
Cytogenetic Map	1	p36.13	NCBI
HuRef	1	17,911,593 - 18,058,372 (-)	NCBI		HuRef
CHM1_1	1	19,774,569 - 19,921,335 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	19,162,310 - 19,308,992 (-)	NCBI		T2T-CHM13v2.0

Capzb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	138,920,210 - 139,019,131 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	138,920,210 - 139,019,129 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	139,192,899 - 139,291,820 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	139,192,899 - 139,291,818 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	138,748,846 - 138,847,727 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	138,465,007 - 138,563,888 (+)	NCBI		MGSCv36	mm8
Celera	4	140,979,100 - 141,078,244 (+)	NCBI		Celera
Cytogenetic Map	4	D3	NCBI
cM Map	4	70.59	NCBI

Capzb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	30,589 - 169,693 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	34,454 - 168,514 (-)	NCBI	ChiLan1.0	ChiLan1.0

CAPZB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	207,629,992 - 207,776,614 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	206,746,732 - 206,893,412 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	18,297,434 - 18,444,011 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	19,343,400 - 19,489,072 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	19,344,154 - 19,488,133 (-)	Ensembl	panpan1.1		panPan2

CAPZB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	79,182,668 - 79,311,529 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	79,181,851 - 79,311,518 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	75,695,344 - 75,825,750 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	79,804,060 - 79,934,792 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	79,804,081 - 79,934,830 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	76,565,507 - 76,695,821 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	77,575,195 - 77,705,390 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	78,644,515 - 78,775,092 (+)	NCBI		UU_Cfam_GSD_1.0

Capzb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	39,769,740 - 39,884,578 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	5,594,152 - 5,709,315 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	5,594,193 - 5,656,665 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CAPZB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	77,780,682 - 77,912,617 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	77,780,682 - 77,912,653 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	71,842,816 - 71,985,460 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CAPZB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	113,062,077 - 113,207,983 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	113,062,192 - 113,210,430 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	2,951,087 - 3,096,887 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Capzb
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	4,473,606 - 4,601,286 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	4,473,880 - 4,601,260 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Capzb
508 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	74
Count of miRNA genes:	56
Interacting mature miRNAs:	71
Transcripts:	ENSRNOT00000010308
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
2302369	Scl60	Serum cholesterol level QTL 60	3.13		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	143608201	161165651	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	135927956	166875058	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	135929696	166875058	Rat
1300119	Bp180	Blood pressure QTL 180	3.82		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	144358090	157869054	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
1354631	Swd2	Spike wave discharge measurement QTL 2	3.64	0.0002	brain electrophysiology trait (VT:0010557)	brain total spike-and-wave discharge duration (CMO:0001740)	5	151113452	164465185	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
631263	Cm24	Cardiac mass QTL 24	3.5		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	5	143799107	158428037	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	143069996	166846814	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
631272	Lanf1	Left ventricular atrial natriuretic factor QTL 1	12		heart left ventricle natriuretic peptide A amount (VT:0010596)	heart left ventricle natriuretic peptide A level (CMO:0002165)	5	151113452	166875058	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
2313096	Bmd78	Bone mineral density QTL 78	3.1	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	5	144377876	161317411	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
1298090	Bp155	Blood pressure QTL 155	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	151006154	161165494	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat

Markers in Region

RH128327

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	151,535,126 - 151,535,346 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	157,742,202 - 157,742,421	NCBI	Rnor6.0
Rnor_5.0	5	161,482,436 - 161,482,655	UniSTS	Rnor5.0
RGSC_v3.4	5	158,080,400 - 158,080,619	UniSTS	RGSC3.4
Celera	5	149,915,466 - 149,915,685	UniSTS
RH 3.4 Map	5	1035.9	UniSTS
Cytogenetic Map	5	q36	UniSTS

RH143222

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	151,514,735 - 151,514,883 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	157,721,814 - 157,721,961	NCBI	Rnor6.0
Rnor_5.0	5	161,462,048 - 161,462,195	UniSTS	Rnor5.0
RGSC_v3.4	5	158,060,012 - 158,060,159	UniSTS	RGSC3.4
Celera	5	149,895,049 - 149,895,196	UniSTS
RH 3.4 Map	5	1036.4	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001005903	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239171	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239172	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239174	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239175	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006239177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109680	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109681	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109682	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC083861	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ218507	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227713	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233583	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000010308 ⟹ ENSRNOP00000010308

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,435,680 - 151,535,409 (+)	Ensembl
Rnor_6.0 Ensembl	5	157,642,777 - 157,742,478 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000083577 ⟹ ENSRNOP00000070586

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,458,196 - 151,535,409 (+)	Ensembl
Rnor_6.0 Ensembl	5	157,642,751 - 157,742,161 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099328 ⟹ ENSRNOP00000085427

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,436,582 - 151,535,409 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000100786 ⟹ ENSRNOP00000090455

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,435,934 - 151,535,344 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000101104 ⟹ ENSRNOP00000086771

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,434,871 - 151,535,409 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104673 ⟹ ENSRNOP00000093194

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,482,499 - 151,535,409 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106969 ⟹ ENSRNOP00000092671

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,436,582 - 151,535,409 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110243 ⟹ ENSRNOP00000093333

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,475,626 - 151,535,409 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115619 ⟹ ENSRNOP00000097982

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,441,001 - 151,535,409 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118044 ⟹ ENSRNOP00000092834

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	151,440,515 - 151,535,409 (+)	Ensembl

RefSeq Acc Id:

NM_001005903 ⟹ NP_001005903

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,718,921 - 156,818,623 (+)	NCBI
mRatBN7.2	5	151,435,704 - 151,535,409 (+)	NCBI
Rnor_6.0	5	157,642,777 - 157,742,484 (+)	NCBI
Rnor_5.0	5	161,383,315 - 161,482,718 (+)	NCBI
RGSC_v3.4	5	157,980,877 - 158,080,682 (+)	RGD
Celera	5	149,816,061 - 149,915,748 (+)	RGD

Sequence:

show sequence

CGGGGAAGTGGAAGCGCCGGGCCCTGCTGCGGGGGGGAGAGCCACAGACGCCGGGACTGGGACC
GTCGCCGCCGCCGCCACCATGAGCGATCAGCAGCTGGACTGCGCCTTGGACCTGATGAGGCGCC
TGCCTCCACAGCAGATTGAGAAAAACCTCAGCGATCTGATCGACCTGGTCCCCAGTCTGTGTGA
AGATCTCCTGTCTTCTGTTGACCAGCCCCTGAAAATTGCCAGAGACAAGGTGGTGGGCAAGGAC
TACCTTTTGTGTGACTACAACAGAGACGGGGACTCCTATAGGTCACCATGGAGTAACAAGTATG
ACCCTCCTTTGGAAGATGGGGCCATGCCATCTGCTCGGCTCAGAAAGCTGGAGGTAGAGGCCAA
CAATGCCTTCGACCAATACCGAGACCTGTATTTTGAAGGTGGTGTCTCATCAGTCTACCTCTGG
GATCTCGATCATGGCTTTGCTGGAGTGATCCTCATAAAGAAGGCTGGGGATGGATCAAAGAAGA
TCAAAGGCTGCTGGGATTCCATCCACGTGGTGGAAGTGCAGGAGAAGTCCAGTGGCCGTACTGC
CCATTACAAGTTGACCTCCACAGTGATGCTATGGCTGCAAACCAACAAATCCGGCTCAGGCACC
ATGAACCTGGGAGGCAGCCTAACCAGACAGATGGAGAAGGACGAAACTGTGAGTGACTGTTCCC
CACACATAGCCAACATTGGGCGCCTGGTGGAGGACATGGAAAACAAAATCAGAAGCACGCTGAA
TGAGATCTACTTTGGAAAAACAAAGGACATCGTCAACGGGCTGAGGTCTGTGCAGACGTTTGCA
GACAAATCAAAGCAGGAAGCCCTTAAGAATGACCTGGTGGAAGCCTTGAAGAGAAAGCAGCAGT
GTTAAAGACCTGCTTCACGCTAACCGGACACGCCATGCACTCGTTAGGTTCCTTTCTTTAGAAA
ACTCGTTTTCTGCTCCTTTTCCCTCTTCCTTTCCCTCCCTGACGGTCACATAACAGTTTGCATC
GACCACGCAGCGCCATCTCTCCCCCAAAATAAAGTCCAATAACCACCCTCTGGCTCCAAGGCCT
GCTTCCCACGACGTTTCCATAGAGACCGTGTGGCTTTGTTCGCCTGTCCCCTTCCTTCCCTTGC
CCGTTTGTAGGCACAGGCGCACTGTCTGACATCCTCCCTCCGTCTTTTTGTTACATTGGTGTAA
AAAATGTAAAACAAAAAAATTTTATGAACTAACTGGTGTGTGAAAGAAGGGAAACTGGAGCTCT
GATCCGTGTGTGTTTGGGGGTTGCTTGGAGCCGGGGGCCGGGGGACAGGGGACAGCTATGGAGG
AAGGAGACATGTCCTCAGCACTGTCCTGCGCAGAGCAGGTGTGCCCTTGTCCCAAGGAGACCGC
GGTGGGGGTGGGGGCGGGGCTGGCGACCGCTGCTCTCTGGCCAGGTGCTTTTCTGTCAAATTTT
TATGGAATGCAAAAGGAGTTTTTTGTTTTATTTTGTTTTTTGTAAAGCTTAAACAGACAAAAAA
AATCTACATCTTCTACTTGAGCCTCCATACTTAAAAAAAAAAAAGGAAAAAAAGAACAAAAAAA
ATAAATAAAAAGAAACTGGGACACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006239172 ⟹ XP_006239234

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,720,037 - 156,818,623 (+)	NCBI
mRatBN7.2	5	151,436,871 - 151,535,384 (+)	NCBI
Rnor_6.0	5	157,643,460 - 157,742,437 (+)	NCBI
Rnor_5.0	5	161,383,315 - 161,482,718 (+)	NCBI

Sequence:

show sequence

GACTTCTCACGACTTAAACCTAGCCTGCGTCAGCCCTGCGCTGCTCTTACCCTCACCCTCCCAT
CTAGACCCTGCTTGCTCGGTGTCCTGCTCCTAACCCAGGTGTCCCCTCCCCTGTTCCTAGGAGG
CTCTTCCTTGGCAGCCTCTGGTGAGCGGGGGAGAGCCCCAACCAGGGTGGGGGTAGTCCGGGTG
CTGTGCCTTTCCTAGGCTTGCCCCTTTCTGGGGAGGCCGCTTAGGTTCGGTGTGAGTGAACAAG
CGAGCAAGGGAGAGAAGGGCGGCATCTGTGTGCCCGGAAGGCAGAGCAGGGCATTTCCCTTGGG
AGGCCCTAGAGCAGCTAATACAGCGCGTATTTAGGGGTGCCCTGCCTGAGTCGGGGAGCAGAGT
GCTGACGGTGGGTAAGCCAAGTGGACAGGGGTGAACTCACAATCGCTCTTGTGAGGCCACAGCC
TTGGGGCTGGGGGACACCAAGCTCAGCAGCCCATCCTTCAGCCTGGACATGATGCATCCTAGCA
GGCGCAGCCTTCCTTTCCCCCTGAACTGTCAGCTTGTAAGGGTTGGAACTGCTGATTATGGAGG
TGCCGCTGATCAGACCATGTGCATCAACCAAGTGGAACAGTCTGAGGGCTTCACGTGGCAAGAC
GGACGGTCTGAAATGAACTCTAGCGATCAGCAGCTGGACTGCGCCTTGGACCTGATGAGGCGCC
TGCCTCCACAGCAGATTGAGAAAAACCTCAGCGATCTGATCGACCTGGTCCCCAGTCTGTGTGA
AGATCTCCTGTCTTCTGTTGACCAGCCCCTGAAAATTGCCAGAGACAAGGTGGTGGGCAAGGAC
TACCTTTTGTGTGACTACAACAGAGACGGGGACTCCTATAGGTCACCATGGAGTAACAAGTATG
ACCCTCCTTTGGAAGATGGGGCCATGCCATCTGCTCGGCTCAGAAAGCTGGAGGTAGAGGCCAA
CAATGCCTTCGACCAATACCGAGACCTGTATTTTGAAGGTGGTGTCTCATCAGTCTACCTCTGG
GATCTCGATCATGGCTTTGCTGGAGTGATCCTCATAAAGAAGGCTGGGGATGGATCAAAGAAGA
TCAAAGGCTGCTGGGATTCCATCCACGTGGTGGAAGTGCAGGAGAAGTCCAGTGGCCGTACTGC
CCATTACAAGTTGACCTCCACAGTGATGCTATGGCTGCAAACCAACAAATCCGGCTCAGGCACC
ATGAACCTGGGAGGCAGCCTAACCAGACAGATGGAGAAGGACGAAACTGTGAGTGACTGTTCCC
CACACATAGCCAACATTGGGCGCCTGGTGGAGGACATGGAAAACAAAATCAGAAGCACGCTGAA
TGAGATCTACTTTGGAAAAACAAAGGACATCGTCAACGGGCTGAGGTCTGTGCAGACGTTTGCA
GACAAATCAAAGCAGGAAGCCCTTAAGAATGACCTGGTGGAAGCCTTGAAGAGAAAGCAGCAGT
GTTAAAGACCTGCTTCACGCTAACCGGACACGCCATGCACTCGTTAGGTTCCTTTCTTTAGAAA
ACTCGTTTTCTGCTCCTTTTCCCTCTTCCTTTCCCTCCCTGACGGTCACATAACAGTTTGCATC
GACCACGCAGCGCCATCTCTCCCCCAAAATAAAGTCCAATAACCACCCTCTGGCTCCAAGGCCT
GCTTCCCACGACGTTTCCATAGAGACCGTGTGGCTTTGTTCGCCTGTCCCCTTCCTTCCCTTGC
CCGTTTGTAGGCACAGGCGCACTGTCTGACATCCTCCCTCCGTCTTTTTGTTACATTGGTGTAA
AAAATGTAAAACAAAAAAATTTTATGAACTAACTGGTGTGTGAAAGAAGGGAAACTGGAGCTCT
GATCCGTGTGTGTTTGGGGGTTGCTTGGAGCCGGGGGCCGGGGGACAGGGGACAGCTATGGAGG
AAGGAGACATGTCCTCAGCACTGTCCTGCGCAGAGCAGGTGTGCCCTTGTCCCAAGGAGACCGC
GGTGGGGGTGGGGGCGGGGCTGGCGACCGCTGCTCTCTGGCCAGGTGCTTTTCTGTCAAATTTT
TATGGAATGCAAAAGGAGTTTTTTGTTTTATTTTGTTTTTTGTAAAGCTTAAACAGACAAAAAA
AATCTACATCTTCTACTTGAGCCTCCATACTTAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006239175 ⟹ XP_006239237

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,719,062 - 156,818,623 (+)	NCBI
mRatBN7.2	5	151,436,412 - 151,535,384 (+)	NCBI
Rnor_6.0	5	157,643,465 - 157,742,437 (+)	NCBI
Rnor_5.0	5	161,383,315 - 161,482,718 (+)	NCBI

Sequence:

show sequence

CTCACGACTTAAACCTAGCCTGCGTCAGCCCTGCGCTGCTCTTACCCTCACCCTCCCATCTAGA
CCCTGCTTGCTCGGTGTCCTGCTCCTAACCCAGGTGTCCCCTCCCCTGTTCCTAGGAGGCTCTT
CCTTGGCAGCCTCTGGTGAGCGGGGGAGAGCCCCAACCAGGGTGGGGGTAGTCCGGGTGCTGTG
CCTTTCCTAGGCTTGCCCCTTTCTGGGGAGGCCGCTTAGGTTCGGTGTGAGTGAACAAGCGAGC
AAGGGAGAGAAGGGCGGCATCTGTGTGCCCGGAAGGCAGAGCAGGGCATTTCCCTTGGGAGGCC
CTAGAGCAGCTAATACAGCGCGTATTTAGGGGTGCCCTGCCTGAGTCGGGGAGCAGAGTGCTGA
CGGTGGGTAAGCCAAGTGGACAGGGGTGAACTCACAATCGCTCTTGTGAGGCCACAGCCTTGGG
GCTGGGGGACACCAAGCTCAGCAGCCCATCCTTCAGCCTGGACATGATGCATCCTAGCAGGCGC
AGCCTTCCTTTCCCCCTGAACTGTCAGCTTGTAAGGGTTGGAACTGCTGATTATGGAGGTGCCG
CTGATCAGAGCGATCAGCAGCTGGACTGCGCCTTGGACCTGATGAGGCGCCTGCCTCCACAGCA
GATTGAGAAAAACCTCAGCGATCTGATCGACCTGGTCCCCAGTCTGTGTGAAGATCTCCTGTCT
TCTGTTGACCAGCCCCTGAAAATTGCCAGAGACAAGGTGGTGGGCAAGGACTACCTTTTGTGTG
ACTACAACAGAGACGGGGACTCCTATAGGTCACCATGGAGTAACAAGTATGACCCTCCTTTGGA
AGATGGGGCCATGCCATCTGCTCGGCTCAGAAAGCTGGAGGTAGAGGCCAACAATGCCTTCGAC
CAATACCGAGACCTGTATTTTGAAGGTGGTGTCTCATCAGTCTACCTCTGGGATCTCGATCATG
GCTTTGCTGGAGTGATCCTCATAAAGAAGGCTGGGGATGGATCAAAGAAGATCAAAGGCTGCTG
GGATTCCATCCACGTGGTGGAAGTGCAGGAGAAGTCCAGTGGCCGTACTGCCCATTACAAGTTG
ACCTCCACAGTGATGCTATGGCTGCAAACCAACAAATCCGGCTCAGGCACCATGAACCTGGGAG
GCAGCCTAACCAGACAGATGGAGAAGGACGAAACTGTGAGTGACTGTTCCCCACACATAGCCAA
CATTGGGCGCCTGGTGGAGGACATGGAAAACAAAATCAGAAGCACGCTGAATGAGATCTACTTT
GGAAAAACAAAGGACATCGTCAACGGGCTGAGGTCTGTGCAGACGTTTGCAGACAAATCAAAGC
AGGAAGCCCTTAAGAATGACCTGGTGGAAGCCTTGAAGAGAAAGCAGCAGTGTTAAAGACCTGC
TTCACGCTAACCGGACACGCCATGCACTCGTTAGGTTCCTTTCTTTAGAAAACTCGTTTTCTGC
TCCTTTTCCCTCTTCCTTTCCCTCCCTGACGGTCACATAACAGTTTGCATCGACCACGCAGCGC
CATCTCTCCCCCAAAATAAAGTCCAATAACCACCCTCTGGCTCCAAGGCCTGCTTCCCACGACG
TTTCCATAGAGACCGTGTGGCTTTGTTCGCCTGTCCCCTTCCTTCCCTTGCCCGTTTGTAGGCA
CAGGCGCACTGTCTGACATCCTCCCTCCGTCTTTTTGTTACATTGGTGTAAAAAATGTAAAACA
AAAAAATTTTATGAACTAACTGGTGTGTGAAAGAAGGGAAACTGGAGCTCTGATCCGTGTGTGT
TTGGGGGTTGCTTGGAGCCGGGGGCCGGGGGACAGGGGACAGCTATGGAGGAAGGAGACATGTC
CTCAGCACTGTCCTGCGCAGAGCAGGTGTGCCCTTGTCCCAAGGAGACCGCGGTGGGGGTGGGG
GCGGGGCTGGCGACCGCTGCTCTCTGGCCAGGTGCTTTTCTGTCAAATTTTTATGGAATGCAAA
AGGAGTTTTTTGTTTTATTTTGTTTTTTGTAAAGCTTAAACAGACAAAAAAAATCTACATCTTC
TACTTGAGCCTCCATACTTAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006239177 ⟹ XP_006239239

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,718,619 - 156,817,838 (+)	NCBI
mRatBN7.2	5	151,435,600 - 151,535,402 (+)	NCBI
Rnor_6.0	5	157,642,742 - 157,742,487 (+)	NCBI
Rnor_5.0	5	161,383,315 - 161,482,718 (+)	NCBI

Sequence:

show sequence

GGGGCNCTGTACCCGGATGTTCACTCTTGGGCACCCGGGGAAGTGGAAGCGCCGGGCCCTGCTG
CGGGGGGGAGAGCCACAGACGCCGGGACTGGGACCGTCGCCGCCGCCGCCACCATGAGCGATCA
GCAGCTGGACTGCGCCTTGGACCTGATGAGGCGCCTGCCTCCACAGCAGATTGAGAAAAACCTC
AGCGATCTGATCGACCTGGTCCCCAGTCTGTGTGAAGATCTCCTGTCTTCTGTTGACCAGCCCC
TGAAAATTGCCAGAGACAAGGTGGTGGGCAAGGACTACCTTTTGTGTGACTACAACAGAGACGG
GGACTCCTATAGGTCACCATGGAGTAACAAGTATGACCCTCCTTTGGAAGATGGGGCCATGCCA
TCTGCTCGGCTCAGAAAGCTGGAGGTAGAGGCCAACAATGCCTTCGACCAATACCGAGACCTGT
ATTTTGAAGGTGGTGTCTCATCAGTCTACCTCTGGGATCTCGATCATGGCTTTGCTGGAGTGAT
CCTCATAAAGAAGGCTGGGGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCATCCACGTG
GTGGAAGTGCAGGAGAAGTCCAGTGGCCGTACTGCCCATTACAAGTTGACCTCCACAGTGATGC
TATGGCTGCAAACCAACAAATCCGGCTCAGGCACCATGAACCTGGGAGGCAGCCTAACCAGACA
GATGGAGAAGGACGAAACTGTGAGTGACTGTTCCCCACACATAGCCAACATTGGGCGCCTGGTG
GAGGACATGGAAAACAAAATCAGAAGCACGCTGAATGAGATCTACTTTGGAAAAACAAAGGACA
TCGTCAACGGGCTGAGATCTCTTGACGCTATCCCCGACAACCACAAGTTTAAGCAGTTGCAGAG
GGAACTTTCTCAAGTGCTGACCCAGCGCCAGGTCTACATCCAGCCTGATAATTGAGCCGACCCA
GGTCTGTGCAGACGTTTGCAGACAAATCAAAGCAGGAAGCCCTTAAGAATGACCTGGTGGAAGC
CTTGAAGAGAAAGCAGCAGTGTTAAAGACCTGCTTCACGCTAACCGGACACGCCATGCACTCGT
TAGGTTCCTTTCTTTAGAAAACTCGTTTTCTGCTCCTTTTCCCTCTTCCTTTCCCTCCCTGACG
GTCACATAACAGTTTGCATCGACCACGCAGCGCCATCTCTCCCCCAAAATAAAGTCCAATAACC
ACCCTCTGGCTCCAAGGCCTGCTTCCCACGACGTTTCCATAGAGACCGTGTGGCTTTGTTCGCC
TGTCCCCTTCCTTCCCTTGCCCGTTTGTAGGCACAGGCGCACTGTCTGACATCCTCCCTCCGTC
TTTTTGTTACATTGGTGTAAAAAATGTAAAACAAAAAAATTTTATGAACTAACTGGTGTGTGAA
AGAAGGGAAACTGGAGCTCTGATCCGTGTGTGTTTGGGGGTTGCTTGGAGCCGGGGGCCGGGGG
ACAGGGGACAGCTATGGAGGAAGGAGACATGTCCTCAGCACTGTCCTGCGCAGAGCAGGTGTGC
CCTTGTCCCAAGGAGACCGCGGTGGGGGTGGGGGCGGGGCTGGCGACCGCTGCTCTCTGGCCAG
GTGCTTTTCTGTCAAATTTTTATGGAATGCAAAAGGAGTTTTTTGTTTTATTTTGTTTTTTGTA
AAGCTTAAACAGACAAAAAAAATCTACATCTTCTACTTGAGCCTCCATACTTAAAAAAAAAAAA
GGAAAAAAAAAACAAAAAAAATAAATAAAAAGAAACTGGGACACAATCA

hide sequence

RefSeq Acc Id:

XM_039109680 ⟹ XP_038965608

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,720,056 - 156,817,838 (+)	NCBI
mRatBN7.2	5	151,436,825 - 151,532,528 (+)	NCBI

RefSeq Acc Id:

XM_039109681 ⟹ XP_038965609

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,719,062 - 156,817,836 (+)	NCBI
mRatBN7.2	5	151,436,412 - 151,532,528 (+)	NCBI

RefSeq Acc Id:

XM_039109682 ⟹ XP_038965610

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	156,719,443 - 156,817,833 (+)	NCBI
mRatBN7.2	5	151,436,225 - 151,535,402 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001005903	(Get FASTA)	NCBI Sequence Viewer
	XP_006239234	(Get FASTA)	NCBI Sequence Viewer
	XP_006239237	(Get FASTA)	NCBI Sequence Viewer
	XP_006239239	(Get FASTA)	NCBI Sequence Viewer
	XP_038965608	(Get FASTA)	NCBI Sequence Viewer
	XP_038965609	(Get FASTA)	NCBI Sequence Viewer
	XP_038965610	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83861	(Get FASTA)	NCBI Sequence Viewer
	EDL80906	(Get FASTA)	NCBI Sequence Viewer
	EDL80907	(Get FASTA)	NCBI Sequence Viewer
	EDL80908	(Get FASTA)	NCBI Sequence Viewer
	EDL80909	(Get FASTA)	NCBI Sequence Viewer
	EDL80910	(Get FASTA)	NCBI Sequence Viewer
	EDL80911	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000010308.5
	ENSRNOP00000070586.2
	ENSRNOP00000085427.1
	ENSRNOP00000086771.1
	ENSRNOP00000090455.1
	ENSRNOP00000092671.1
	ENSRNOP00000092834.1
	ENSRNOP00000093194.1
	ENSRNOP00000093333.1
	ENSRNOP00000097982.1
GenBank Protein	Q5XI32	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001005903 ⟸ NM_001005903

- UniProtKB:

Q5XI32 (UniProtKB/Swiss-Prot), A6ITK5 (UniProtKB/TrEMBL), A0A8I6AWP4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDY
NRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGF
AGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGS
LTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSVQTFADKSKQE
ALKNDLVEALKRKQQC

hide sequence

RefSeq Acc Id:	XP_006239239 ⟸ XM_006239177
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6AWP4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDY NRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGF AGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGS LTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSLDAIPDNHKFK QLQRELSQVLTQRQVYIQPDN hide sequence

RefSeq Acc Id:	XP_006239237 ⟸ XM_006239175
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6A3B7 (UniProtKB/TrEMBL), A0A8I6AWP4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MMHPSRRSLPFPLNCQLVRVGTADYGGAADQSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPS LCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEV EANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSG RTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRS TLNEIYFGKTKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC hide sequence

RefSeq Acc Id:	XP_006239234 ⟸ XM_006239172
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AG02 (UniProtKB/TrEMBL), A0A8L2Q5I8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MMHPSRRSLPFPLNCQLVRVGTADYGGAADQTMCINQVEQSEGFTWQDGRSEMNSSDQQLDCAL DLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSP WSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAG DGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDET VSDCSPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSVQTFADKSKQEALKNDLVEAL KRKQQC hide sequence

Ensembl Acc Id:

ENSRNOP00000010308 ⟸ ENSRNOT00000010308

Ensembl Acc Id:

ENSRNOP00000070586 ⟸ ENSRNOT00000083577

RefSeq Acc Id:	XP_038965610 ⟸ XM_039109682
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6AWP4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038965609 ⟸ XM_039109681
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6AWP4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038965608 ⟸ XM_039109680
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2Q5I8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000092671 ⟸ ENSRNOT00000106969

Ensembl Acc Id:

ENSRNOP00000090455 ⟸ ENSRNOT00000100786

Ensembl Acc Id:

ENSRNOP00000093194 ⟸ ENSRNOT00000104673

Ensembl Acc Id:

ENSRNOP00000097982 ⟸ ENSRNOT00000115619

Ensembl Acc Id:

ENSRNOP00000092834 ⟸ ENSRNOT00000118044

Ensembl Acc Id:

ENSRNOP00000085427 ⟸ ENSRNOT00000099328

Ensembl Acc Id:

ENSRNOP00000086771 ⟸ ENSRNOT00000101104

Ensembl Acc Id:

ENSRNOP00000093333 ⟸ ENSRNOT00000110243

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XI32-F1-model_v2	AlphaFold	Q5XI32	1-272	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694203

Promoter ID:

EPDNEW_R4726

Type:

initiation region

Name:

Capzb_1

Description:

capping actin protein of muscle Z-line beta subunit

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	157,642,760 - 157,642,820	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359099	AgrOrtholog
BioCyc Gene	G2FUF-39422	BioCyc
Ensembl Genes	ENSRNOG00000007330	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000010308.8	UniProtKB/TrEMBL
	ENSRNOT00000083577.2	UniProtKB/TrEMBL
	ENSRNOT00000099328.1	UniProtKB/TrEMBL
	ENSRNOT00000100786.1	UniProtKB/TrEMBL
	ENSRNOT00000101104.1	UniProtKB/TrEMBL
	ENSRNOT00000104673.1	UniProtKB/TrEMBL
	ENSRNOT00000106969.1	UniProtKB/TrEMBL
	ENSRNOT00000110243.1	UniProtKB/TrEMBL
	ENSRNOT00000115619.1	UniProtKB/TrEMBL
	ENSRNOT00000118044.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.58.570	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	3.90.1150.210	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Capz alpha-1 subunit	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7126848	IMAGE-MGC_LOAD
InterPro	CapZ_alpha/beta	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CapZ_alpha/beta_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CAPZB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CAPZB_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	F-actin_capping_bsu_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:298584	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:95097	IMAGE-MGC_LOAD
NCBI Gene	298584	ENTREZGENE
PANTHER	F-ACTIN-CAPPING PROTEIN SUBUNIT BETA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10619	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	F_actin_cap_B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Capzb	PhenoGen
PRINTS	FACTINCAPB	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	F_ACTIN_CAPPING_BETA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000007330	RatGTEx
Superfamily-SCOP	SSF90096	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2JYB1_RAT	UniProtKB/TrEMBL
	A0A8I6A3B7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AG02	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AIB2_RAT	UniProtKB/TrEMBL
	A0A8I6ATR2_RAT	UniProtKB/TrEMBL
	A0A8I6AWP4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AWW7_RAT	UniProtKB/TrEMBL
	A0A8I6GFB3_RAT	UniProtKB/TrEMBL
	A0A8I6GIW5_RAT	UniProtKB/TrEMBL
	A0A8L2Q5I8	ENTREZGENE, UniProtKB/TrEMBL
	A6ITK5	ENTREZGENE, UniProtKB/TrEMBL
	A6ITK6_RAT	UniProtKB/TrEMBL
	A6ITK7_RAT	UniProtKB/TrEMBL
	A6ITL0_RAT	UniProtKB/TrEMBL
	CAPZB_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-05-03	Capzb	capping actin protein of muscle Z-line subunit beta	Capzb	capping actin protein of muscle Z-line beta subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-02-11	Capzb	capping actin protein of muscle Z-line beta subunit	Capzb	capping protein (actin filament) muscle Z-line, beta	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Capzb	capping protein (actin filament) muscle Z-line, beta		F-actin capping protein beta subunit	Name updated	1299863	APPROVED
2005-07-29	Capzb	F-actin capping protein beta subunit			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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