Aktip (AKT interacting protein) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Aktip (AKT interacting protein) Rattus norvegicus
Analyze
Symbol: Aktip
Name: AKT interacting protein
RGD ID: 1311170
Description: Predicted to enable NEDD8 transferase activity. Predicted to be involved in several processes, including early endosome to late endosome transport; protein localization to perinuclear region of cytoplasm; and protein neddylation. Predicted to act upstream of or within positive regulation of protein phosphorylation. Predicted to be located in plasma membrane. Predicted to be part of FHF complex and HOPS complex. Predicted to be active in cytosol and nucleus. Orthologous to human AKTIP (AKT interacting protein); INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: AKT-interacting protein; Fts; fused toes; fused toes protein homolog; LOC291906; MGC109405
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81932,039,507 - 32,059,634 (+)NCBIGRCr8
mRatBN7.21915,866,811 - 15,877,123 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1915,866,928 - 15,886,663 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1917,555,540 - 17,565,425 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01922,750,095 - 22,759,980 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01925,697,676 - 25,707,547 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01917,290,048 - 17,300,054 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1917,290,178 - 17,300,050 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01928,354,053 - 28,373,178 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41917,035,220 - 17,045,096 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11917,040,045 - 17,049,918 (+)NCBI
Celera1915,772,238 - 15,782,114 (+)NCBICelera
Cytogenetic Map19p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
Benzo[k]fluoranthene  (ISO)
bisphenol A  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
diazinon  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
ethanol  (ISO)
fenthion  (ISO)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (EXP)
genistein  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
methidathion  (ISO)
methylmercury chloride  (ISO)
nickel atom  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
potassium chromate  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triptonide  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IBA)
FHF complex  (IEA,ISO,ISS)
HOPS complex  (IEA,ISO)
nucleus  (IBA)
plasma membrane  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14749367   PMID:18799622  


Genomics

Comparative Map Data
Aktip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81932,039,507 - 32,059,634 (+)NCBIGRCr8
mRatBN7.21915,866,811 - 15,877,123 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1915,866,928 - 15,886,663 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1917,555,540 - 17,565,425 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01922,750,095 - 22,759,980 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01925,697,676 - 25,707,547 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01917,290,048 - 17,300,054 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1917,290,178 - 17,300,050 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01928,354,053 - 28,373,178 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41917,035,220 - 17,045,096 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11917,040,045 - 17,049,918 (+)NCBI
Celera1915,772,238 - 15,782,114 (+)NCBICelera
Cytogenetic Map19p11NCBI
AKTIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381653,491,040 - 53,504,412 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1653,491,040 - 53,504,411 (-)EnsemblGRCh38hg38GRCh38
GRCh371653,524,952 - 53,537,121 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361652,082,693 - 52,094,671 (-)NCBINCBI36Build 36hg18NCBI36
Build 341652,083,103 - 52,094,652NCBI
Celera1638,040,003 - 38,051,981 (-)NCBICelera
Cytogenetic Map16q12.2NCBI
HuRef1639,412,663 - 39,424,641 (-)NCBIHuRef
CHM1_11654,932,327 - 54,944,305 (-)NCBICHM1_1
T2T-CHM13v2.01659,288,844 - 59,302,210 (-)NCBIT2T-CHM13v2.0
Aktip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39891,834,267 - 91,862,122 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl891,838,412 - 91,926,604 (-)EnsemblGRCm39 Ensembl
GRCm38891,111,781 - 91,135,494 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl891,111,784 - 91,199,976 (-)EnsemblGRCm38mm10GRCm38
MGSCv37893,647,398 - 93,659,395 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36894,013,604 - 94,025,601 (-)NCBIMGSCv36mm8
Celera895,438,579 - 95,450,369 (-)NCBICelera
Cytogenetic Map8C4NCBI
cM Map844.25NCBI
Aktip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543311,237,717 - 11,248,249 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543311,237,717 - 11,248,638 (-)NCBIChiLan1.0ChiLan1.0
AKTIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21862,926,407 - 62,937,985 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11668,845,024 - 68,856,614 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01633,731,652 - 33,743,571 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11652,815,573 - 52,827,807 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1652,815,559 - 52,827,750 (-)Ensemblpanpan1.1panPan2
AKTIP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1262,253,005 - 62,263,918 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl262,254,320 - 62,263,337 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha258,886,060 - 58,896,994 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0262,794,743 - 62,805,677 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl262,796,373 - 62,805,992 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1259,618,363 - 59,629,310 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0260,638,932 - 60,649,878 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0261,521,329 - 61,532,263 (+)NCBIUU_Cfam_GSD_1.0
Aktip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934953,438,840 - 53,449,200 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364756,139,875 - 6,150,130 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364756,139,875 - 6,150,132 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AKTIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl631,747,606 - 31,758,279 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1631,706,253 - 31,757,878 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
AKTIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1539,283,607 - 39,295,320 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl539,284,308 - 39,295,284 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604737,085,946 - 37,097,680 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aktip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247573,265,389 - 3,294,735 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247573,265,492 - 3,295,406 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Aktip
76 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:388
Count of miRNA genes:242
Interacting mature miRNAs:293
Transcripts:ENSRNOT00000060865
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)191392640130303727Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032318023069265Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat

Markers in Region
RH142012  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21915,876,718 - 15,876,928 (+)MAPPERmRatBN7.2
Rnor_6.01917,299,955 - 17,300,164NCBIRnor6.0
Rnor_5.01928,364,067 - 28,364,276UniSTSRnor5.0
RGSC_v3.41917,044,997 - 17,045,206UniSTSRGSC3.4
Celera1915,782,015 - 15,782,224UniSTS
Cytogenetic Map19p11UniSTS
AI501448  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21915,871,750 - 15,871,943 (+)MAPPERmRatBN7.2
Rnor_6.01917,294,987 - 17,295,179NCBIRnor6.0
Rnor_5.01928,359,099 - 28,359,291UniSTSRnor5.0
RGSC_v3.41917,040,029 - 17,040,221UniSTSRGSC3.4
Celera1915,777,047 - 15,777,239UniSTS
Cytogenetic Map19p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000060865   ⟹   ENSRNOP00000057588
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1915,866,928 - 15,877,121 (+)Ensembl
Rnor_6.0 Ensembl1917,290,178 - 17,300,050 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108713   ⟹   ENSRNOP00000091269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1915,867,224 - 15,877,121 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109943   ⟹   ENSRNOP00000092612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1915,866,939 - 15,886,663 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113279   ⟹   ENSRNOP00000082936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1915,870,699 - 15,877,119 (+)Ensembl
RefSeq Acc Id: NM_001011926   ⟹   NP_001011926
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,039,780 - 32,049,656 (+)NCBI
mRatBN7.21915,866,941 - 15,876,818 (+)NCBI
Rnor_6.01917,290,178 - 17,300,054 (+)NCBI
Rnor_5.01928,354,053 - 28,373,178 (+)NCBI
RGSC_v3.41917,035,220 - 17,045,096 (+)RGD
Celera1915,772,238 - 15,782,114 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255182   ⟹   XP_006255244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,039,746 - 32,049,656 (+)NCBI
mRatBN7.21915,866,907 - 15,876,808 (+)NCBI
Rnor_6.01917,290,177 - 17,300,054 (+)NCBI
Rnor_5.01928,354,053 - 28,373,178 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601205   ⟹   XP_017456694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,039,507 - 32,049,656 (+)NCBI
mRatBN7.21915,866,811 - 15,876,808 (+)NCBI
Rnor_6.01917,290,048 - 17,300,054 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601206   ⟹   XP_017456695
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,039,567 - 32,049,656 (+)NCBI
mRatBN7.21915,866,811 - 15,876,818 (+)NCBI
Rnor_6.01917,290,048 - 17,300,054 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097569   ⟹   XP_038953497
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,042,422 - 32,049,656 (+)NCBI
mRatBN7.21915,866,941 - 15,876,818 (+)NCBI
RefSeq Acc Id: XM_063277863   ⟹   XP_063133933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,039,993 - 32,049,656 (+)NCBI
RefSeq Acc Id: XM_063277864   ⟹   XP_063133934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,039,991 - 32,049,656 (+)NCBI
RefSeq Acc Id: XM_063277865   ⟹   XP_063133935
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81932,039,999 - 32,059,634 (+)NCBI
RefSeq Acc Id: NP_001011926   ⟸   NM_001011926
- UniProtKB: Q5FVH4 (UniProtKB/Swiss-Prot),   A6KD80 (UniProtKB/TrEMBL),   A0A8I6GA43 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255244   ⟸   XM_006255182
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AQ33 (UniProtKB/TrEMBL),   A0A8I6GA43 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456694   ⟸   XM_017601205
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GA43 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456695   ⟸   XM_017601206
- Peptide Label: isoform X2
- UniProtKB: A0A8I6GA43 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000057588   ⟸   ENSRNOT00000060865
RefSeq Acc Id: XP_038953497   ⟸   XM_039097569
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000091269   ⟸   ENSRNOT00000108713
Ensembl Acc Id: ENSRNOP00000082936   ⟸   ENSRNOT00000113279
Ensembl Acc Id: ENSRNOP00000092612   ⟸   ENSRNOT00000109943
RefSeq Acc Id: XP_063133934   ⟸   XM_063277864
- Peptide Label: isoform X4
- UniProtKB: Q5FVH4 (UniProtKB/Swiss-Prot),   A6KD80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133933   ⟸   XM_063277863
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AQ33 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133935   ⟸   XM_063277865
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AI00 (UniProtKB/TrEMBL),   A6KD77 (UniProtKB/TrEMBL)
Protein Domains
UBC core

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5FVH4-F1-model_v2 AlphaFold Q5FVH4 1-292 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700973
Promoter ID:EPDNEW_R11496
Type:initiation region
Name:Aktip_1
Description:AKT interacting protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01917,290,169 - 17,290,229EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311170 AgrOrtholog
BioCyc Gene G2FUF-6360 BioCyc
Ensembl Genes ENSRNOG00000011956 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000060865.3 UniProtKB/TrEMBL
  ENSRNOT00000108713.1 UniProtKB/TrEMBL
  ENSRNOT00000109943.1 UniProtKB/TrEMBL
  ENSRNOT00000113279.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.110.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7318380 IMAGE-MGC_LOAD
InterPro Ub_conjugating_enzyme UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBQ-conjugat_E2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBQ-conjugating_enzyme/RWD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:291906 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:109405 IMAGE-MGC_LOAD
NCBI Gene 291906 ENTREZGENE
PANTHER PROTEIN CROSSBRONX-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBIQUITIN-CONJUGATING ENZYME E2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam UQ_con UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Aktip PhenoGen
PROSITE UBC_2 UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000011956 RatGTEx
SMART UBCc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54495 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AI00 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AQ33 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GA43 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QUG0_RAT UniProtKB/TrEMBL
  A6KD77 ENTREZGENE, UniProtKB/TrEMBL
  A6KD80 ENTREZGENE, UniProtKB/TrEMBL
  AKTIP_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-20 Aktip  AKT interacting protein  Fts  fused toes  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Fts  fused toes  Fts_predicted  fused toes (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Fts_predicted  fused toes (predicted)      Symbol and Name status set to approved 70820 APPROVED